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https://www.readbyqxmd.com/read/28721093/gout-mimicking-spondyloarthritis-case-report-and-literature-review
#1
Wenji Chen, Yanyan Wang, Yan Li, Zheng Zhao, Lixia Feng, Jian Zhu, Jianglin Zhang, Feng Huang
Gout is clinically characterized by episodes of monoarthritis, which not only typically affects the peripheral joints but also occasionally affect the axial joint, such as the sacroiliac joint (SIJ), and often mimics spondyloarthritis (SpA). Two cases of gout mimicking SpA are presented in the current paper. One patient was a 32-year-old man with a history of asymmetrical oligoarthritis of ankle and metatarsophalangeal joints (MTPJ). He had left gluteal pain for 2 weeks. Computed tomography (CT) and magnetic resonance imaging (MRI) revealed the bone erosion of the left SIJ...
2017: Journal of Pain Research
https://www.readbyqxmd.com/read/28698330/clinical-characteristics-of-importance-to-outcome-in-patients-with-axial-spondyloarthritis-protocol-for-a-prospective-descriptive-and-exploratory-cohort-study
#2
Rikke Asmussen Andreasen, Lars Erik Kristensen, Torkell Ellingsen, Robin Christensen, Xenofon Baraliakos, Jimmi Wied, Claus Aalykke, Thomas Ulstrup, Berit Schiøttz-Christensen, Hans Christian Horn, Amir Emamifar, Bent Duerlund, Lars Fischer, Inger Marie Jensen Hansen
INTRODUCTION: Spondyloarthritis (SpA) is a heterogeneous spectrum of rheumatic diseases with either predominantly axial inflammatory symptoms of the spine and sacroiliac joints or predominantly peripheral arthritis. The two main entities of axial SpA (axSpA) are ankylosing spondylitis or non-radiographic axSpA (nr-axSpA). Tumour necrosis factor-α inhibitors have revolutionised the treatment of patients with axSpA who failed to respond to non-steroidal anti-inflammatory drugs and physical therapy...
July 10, 2017: BMJ Open
https://www.readbyqxmd.com/read/28693033/axial-involvement-according-to-asas-criteria-in-an-observational-psoriatic-arthritis-cohort
#3
Pedro David Carvalho, Florencia Savy, Carmen Moragues, Xavier Juanola, Jesus Rodriguez-Moreno
The definition of axial involvement in psoriatic arthritis (PsA) is still under debate. Currently, the axial spondyloarthritis (SpA) criteria defined by Assessment of Spondyloarthritis International Society (ASAS) may be the most adequate.(1) The aims of present study were to assess axial involvement according to ASAS criteria in an observational PsA cohort and define the clinical characteristics more associated with this kind of involvement. Our study included consecutive patients who had a visit in a tertiary Rheumatology centre...
April 2017: Acta Reumatológica Portuguesa
https://www.readbyqxmd.com/read/28684559/treating-axial-spondyloarthritis-and-peripheral-spondyloarthritis-especially-psoriatic-arthritis-to-target-2017-update-of-recommendations-by-an-international-task-force
#4
Josef S Smolen, Monika Schöls, Jürgen Braun, Maxime Dougados, Oliver FitzGerald, Dafna D Gladman, Arthur Kavanaugh, Robert Landewé, Philip Mease, Joachim Sieper, Tanja Stamm, Maarten de Wit, Daniel Aletaha, Xenofon Baraliakos, Neil Betteridge, Filip van den Bosch, Laura C Coates, Paul Emery, Lianne S Gensler, Laure Gossec, Philip Helliwell, Merryn Jongkees, Tore K Kvien, Robert D Inman, Iain B McInnes, Mara Maccarone, Pedro M Machado, Anna Molto, Alexis Ogdie, Denis Poddubnyy, Christopher Ritchlin, Martin Rudwaleit, Adrian Tanew, Bing Thio, Douglas Veale, Kurt de Vlam, Désirée van der Heijde
Therapeutic targets have been defined for axial and peripheral spondyloarthritis (SpA) in 2012, but the evidence for these recommendations was only of indirect nature. These recommendations were re-evaluated in light of new insights. Based on the results of a systematic literature review and expert opinion, a task force of rheumatologists, dermatologists, patients and a health professional developed an update of the 2012 recommendations. These underwent intensive discussions, on site voting and subsequent anonymous electronic voting on levels of agreement with each item...
July 6, 2017: Annals of the Rheumatic Diseases
https://www.readbyqxmd.com/read/28682112/etanercept-for-treating-axial-spondyloarthritis
#5
Xavier Guillot, Clément Prati, Maxime Sondag, Daniel Wendling
Axial spondyloarthritis is an inflammatory rheumatic disease causing back pain, functional impairment and potential ankylosis in the advanced stage. In this context, TNF blockers have been a major therapeutic advance. Etanercept is a soluble recombinant TNF receptor fusion protein in this vain. Areas covered: The aim of this review is to summarize the current published data concerning the efficacy and tolerance of etanercept in axial spondyloarthrits. The authors performed a systematic review on PubMed, using 'etanercept' and 'spondyloarthritis', 'axial spondyloarthritis' or 'ankylosing spondylitis' keywords...
July 6, 2017: Expert Opinion on Biological Therapy
https://www.readbyqxmd.com/read/28662723/hla-b27-antigen-in-middle-eastern-and-arab-countries-systematic-review-of-the-strength-of-association-with-axial-spondyloarthritis-and-methodological-gaps
#6
Nelly Raymond Ziade
BACKGROUND: Axial spondyloarthritis (AxSpA) is a relatively frequent and debilitating disease, with a prevalence ranging from 0.1 to 2% in the Caucasian population. Current Assessment of Spondyloarthritis International Society (ASAS) classification criteria of AxSpA rely either on sacroiliitis on imaging plus one SpA feature or positive HLAB27 antigen plus two SpA features, in a patient with chronic low back pain and age at onset of less than 45 years. Therefore, HLA-B27 is a central feature in SpA classification and plays a pivotal role in referral strategies and early diagnosis...
June 29, 2017: BMC Musculoskeletal Disorders
https://www.readbyqxmd.com/read/28612240/clinical-characteristics-of-peripheral-spondyloarthritis-without-psoriasis-inflammatory-enteropathy-or-preceding-infection-from-a-single-rheumatology-clinic-in-northern-india
#7
Anand Narayan Malaviya, Neha Agrawal, Nilesh Sahebrao Patil
The objective of this study was to characterise the peripheral arthritis of spondyloarthritis (pSpA) excluding psoriatic-, inflammatory enteropathy-related, post-infectious reactive-SpA and arthritis associated with axial SpA/ankylosing spondylitis (axSpA/AS). Patients presenting with the clinical features of the broad spectrum of SpA were screened for the presence of peripheral arthritis using the Assessment of SpondyloArthritis International Society (ASAS) criteria. The other conditions that could cause pSpA, e...
June 13, 2017: Clinical Rheumatology
https://www.readbyqxmd.com/read/28593426/-spondyloarthritides
#8
M Rudwaleit
Spondyloarthritides (SpA) are inflammatory rheumatic diseases affecting the axial skeleton, peripheral joints and entheses, and also manifest at extraskeletal sites. According to the more recently introduced nomenclature, predominant axial SpA is distinguished from predominant peripheral SpA. Axial SpA is further divided into radiographic and nonradiographic axial SpA. Genetic factors are relevant, with HLA-B27 being most important. The interleukin 23/17 pathway seems to be relevant and points towards new therapeutic targets...
June 7, 2017: Der Internist
https://www.readbyqxmd.com/read/28569568/performance-of-the-classification-criteria-in-patients-with-late-onset-axial-spondyloarthritis
#9
Louise T Bendahan, Natália P Machado, Jamille G Mendes, Thauana L Oliveira, Marcelo M Pinheiro
AIM: To evaluate the performance of four different classification criteria for spondyloarthritis (SpA) in patients with late-onset symptoms and to compare the clinical, laboratory and radiographic outcomes among the patients with symptoms before and after 45 years of age. PATIENTS AND METHODS: A total of 329 patients with SpA were enrolled in this prospective cohort. Patients with psoriatic arthritis, reactive arthritis, colitis associated arthritis and peripheral or undifferentiated SpA were excluded...
June 1, 2017: Modern Rheumatology
https://www.readbyqxmd.com/read/28569222/is-the-current-asas-expert-definition-of-a-positive-family-history-useful-in-identifying-axial-spondyloarthritis-results-from-the-space-and-desir-cohorts
#10
Zineb Ez-Zaitouni, Andrea Hilkens, Laure Gossec, Inger Jorid Berg, Robert Landewé, Roberta Ramonda, Maxime Dougados, Désirée van der Heijde, Floris van Gaalen
BACKGROUND: The Assessment of SpondyloArthritis international Society (ASAS) definition of a positive family history (PFH) of spondyloarthritis (SpA) includes the following diseases in first- or second-degree relatives: ankylosing spondylitis (AS), acute anterior uveitis (AAU), reactive arthritis (ReA), inflammatory bowel disease (IBD), and psoriasis. However, it is not known if a PFH for each of these diseases contributes to making a diagnosis of axSpA, sacroiliitis on imaging, or fulfilling the ASAS criteria in patients presenting with chronic back pain (CBP)...
May 31, 2017: Arthritis Research & Therapy
https://www.readbyqxmd.com/read/28555158/the-nonradiographic-axial-spondyloarthritis-the-radiographic-axial-spondyloarthritis-and-ankylosing-spondylitis-the-tangled-skein-of-rheumatology
#11
REVIEW
Anand N Malaviya, Roopa Rawat, Neha Agrawal, Nilesh S Patil
Since 1984 the diagnosis of ankylosing spondylitis (AS) has been based upon the modified New York (mNY) criteria with mandatory presence of radiographic sacroiliitis, without which the diagnosis is not tenable. However, it may take years or decades for radiographic sacroiliitis to develop delaying the diagnosis for long periods. It did not matter in the past because no effective treatment was available. However, with the availability of a highly effective treatment, namely, tumour necrosis factor-α inhibitors (TNFi), the issue of early diagnosis of AS acquired an urgency...
2017: International Journal of Rheumatology
https://www.readbyqxmd.com/read/28539676/results-from-polish-spondyloarthritis-initiative-registry-polspi-methodology-and-data-from-the-first-year-of-observation
#12
Zofia Guła, Tacjana Barczyńska, Marek Brzosko, Jerzy Gąsowski, Sławomir Jeka, Katarzyna Jodłowska-Cicio, Beata Kwaśny-Krochin, Piotr Leszczyński, Łukasz Lubiński, Katarzyna Łosińska, Katarzyna Pawlak-Buś, Hanna Przepiera-Będzak, Włodzimierz Samborski, Małgorzata Schlabs, Maciej Siedlar, Dorota Sikorska, Jerzy Świerkot, Małgorzata Węgierska, Piotr Wiland, Mariusz Korkosz
OBJECTIVES: Report on one-year results from the Polish Spondyloarthritis Initiative registry (PolSPI), containing the cross-sectional analysis of clinical and imaging data as well as database methodology. MATERIAL AND METHODS: The PolSPI registry includes patients with axial (axSpA) and peripheral (perSpA) spondyloarthritis according to ASAS classification criteria, and/or patients with ankylosing spondylitis according to modified New York criteria, psoriatic arthritis according to CASPAR criteria, arthropathy in inflammatory bowel disease, reactive arthritis, juvenile spondyloarthritis or undifferentiated spondyloarthritis...
2017: Reumatologia
https://www.readbyqxmd.com/read/28511725/the-performance-of-different-classification-criteria-sets-for-spondyloarthritis-in-the-worldwide-asas-comospa-study
#13
Pauline Bakker, Anna Moltó, Adrien Etcheto, Filip Van den Bosch, Robert Landewé, Floris van Gaalen, Maxime Dougados, Désirée van der Heijde
BACKGROUND: In this study, we sought to compare the performance of spondyloarthritis (SpA) classification criteria sets in an international SpA cohort with patients included from five continents around the world. METHODS: Data from the (ASAS) COMOrbidities in SPondyloArthritis (ASAS-COMOSPA) study were used. ASAS-COMOSPA is a multinational, cross-sectional study with consecutive patients diagnosed with SpA by rheumatologists worldwide. Patients were classified according to the European Spondyloarthropathy Study Group (ESSG), modified European Spondyloarthropathy Study Group (mESSG), Amor, modified Amor, Assessment of SpondyloArthritis international Society (ASAS) axial Spondyloarthritis (axSpA), ASAS peripheral spondyloarthritis (pSpA) and ClASsification criteria for Psoriatic Arthritis (CASPAR) criteria...
May 16, 2017: Arthritis Research & Therapy
https://www.readbyqxmd.com/read/28497237/efficacy-of-long-term-nonsteroidal-antiinflammatory-drug-treatment-on-magnetic-resonance-imaging-determined-bone-marrow-oedema-in-early-active-axial-spondyloarthritis-patients
#14
Mei Tang, Leixi Xue, Yueping Shen, Lin Bo, Ru Yang, Jian Wen, Yi Zhang, Zhichun Liu, Jinxiang Fu
To assess the efficacy of long-term treatment with nonsteroidal antiinflammatory drugs (NSAIDs) on bone marrow oedema (BMO) of the sacroiliac joint in newly diagnosed axial spondyloarthritis (SpA) with a symptom duration of less than 4 years, a single-center, open-label study in a cohort of consecutive patients with newly diagnosed axial SpA was conducted. Eligible patients had magnetic resonance imaging (MRI)-determined BMO of the sacroiliac joint at baseline, had a symptom duration of less than 4 years, and were naïve to NSAIDs...
May 11, 2017: Clinical Rheumatology
https://www.readbyqxmd.com/read/28488046/features-of-the-achilles-tendon-paratenon-and-enthesis-in-inflammatory-rheumatic-diseases-a%C3%A2-clinical-and-ultrasonographic-study
#15
H Harman, E Süleyman
AIM: We analyzed the ultrasonographic (US) features of the Achilles tendon (AT), paratenon (AP), and enthesis in patients with axial spondyloarthropathies (SpA) and rheumatoid arthritis (RA), and compared these to healthy subjects. Relationships between these findings and clinical and functional parameters were identified. METHODS: The study included 40 axial SpA and 27 RA patients, as well as 30 healthy subjects. Clinical evaluation relied on the Bath Ankylosing Spondylitis Disease Activity Index (BASDAI), Bath AS Functional Index (BASFI), AS Quality of Life Questionnaire (ASQoL), Disease Activity Score 28 (DAS28), and Health Assessment Questionnaire (HAQ), as well as on a visual analog scale (VAS) for entheseal pain and the Madrid Sonographic Enthesistis Index (MASEI)...
May 9, 2017: Zeitschrift Für Rheumatologie
https://www.readbyqxmd.com/read/28487138/a-systematic-review-of-quality-of-life-domains-and-items-relevant-to-patients-with-spondyloarthritis
#16
Yu Heng Kwan, Warren Fong, Victoria Ie Ching Tan, Nai Lee Lui, Rahul Malhotra, Truls Østbye, Julian Thumboo
OBJECTIVES: To summarize, from the literature, quality-of-life (QoL) domains and items relevant to patients with spondyloarthritis (SpA), and to determine if commonly used SpA patient-reported outcome (PRO) instruments include the identified domains. METHODS: We used PRISMA statement for systematic review and searched Medline(®) , Embase(®), and PsycInfo(®) using relevant keywords. In addition, hand searches of references of the included articles were conducted...
April 18, 2017: Seminars in Arthritis and Rheumatism
https://www.readbyqxmd.com/read/28464949/monosodium-urate-crystal-deposition-associated-with-the-progress-of-radiographic-grade-at-the-sacroiliac-joint-in-axial-spa-a-dual-energy-ct-study
#17
Junqing Zhu, Aiwu Li, Ertao Jia, Yi Zhou, Juan Xu, Shixian Chen, Yinger Huang, Xiang Xiao, Juan Li
BACKGROUND: Previous studies have revealed that ankylosing spondylitis (AS), as the progenitor of axial spondyloarthritis (AxSpA), has been characterized by the insidiously progressive nature of sacroiliitis and spondylitis. Dual-energy computed tomography (DECT) has recently been used to analyse the deposition of monosodium urate (MSU) crystals with higher sensitivity and specificity. However, it remains unclear whether the existence of the MSU crystal deposition detected by DECT at the sacroiliac joint in patients with AxSpA also is associated with the existing structural damage...
May 2, 2017: Arthritis Research & Therapy
https://www.readbyqxmd.com/read/28412702/case-control-study-on-dactylitis-enthesitis-and-anterior-uveitis-in-spondyloarthritis-associated-with-inflammatory-bowel-diseases-role-of-coexistent-psoriasis
#18
Fabrizio Cantini, Laura Niccoli, Carlotta Nannini, Emanuele Cassarà, Olga Kaloudi, Fernando Rizzello, Paolo Gionchetti
OBJECTIVE: To evaluate the frequency of dactylitis, enthesitis, and anterior uveitis (AU) in spondyloarthritis (SpA) associated with inflammatory bowel disease (IBD-SpA) compared with other SpA, and to assess the role of associated psoriasis in the occurrence of dactylitis and enthesitis. METHODS: In a 12-month case-control study, the frequency of dactylitis and enthesitis in 29 patients with ulcerative colitis (UC) and 59 with Crohn disease (CD) who satisfied the Spondyloarthritis international Society criteria for axial or peripheral SpA was compared with 176 controls, including 97 (55...
April 15, 2017: Journal of Rheumatology
https://www.readbyqxmd.com/read/28393709/profile-of-patients-with-spondyloarthritis-in-morocco
#19
Jamila Essouiri, Abourazzak Fatima Ezzahra, Kona Irene, Khoussar Ikram, Harzy Taoufik
OBJECTIVES: to describe the characteristics of our population with spondyloarthritis: diagnostic time, clinical manifestations and laboratory investigations, activity, functional impairment, severity and therapeutic management. The authors were also interested to investigate factors associated with severe disease. METHODS: A retrospective observational study, conducted in the rheumatology department at university hospital center Hassan II of Fez, analyzing the records of patients diagnosed as spondylarthritis during the period extending from January 2009 to June 2014...
April 6, 2017: Current Rheumatology Reviews
https://www.readbyqxmd.com/read/28376062/axial-spondyloarthritis-classification-criteria-the-debate-continues
#20
Maureen Dubreuil, Atul A Deodhar
PURPOSE OF REVIEW: The Assessment of Spondyloarthritis International Society (ASAS) axial spondyloarthritis (axSpA) classification criteria marked a major step forward in SpA research, distinguishing axial from peripheral disease, and allowing earlier identification through MRI. This facilitated all aspects of research including epidemiology, therapeutics and patient outcomes. RECENT FINDINGS: The ASAS axSpA classification criteria have been applied broadly in research, and were validated in a recent meta-analysis of international studies...
July 2017: Current Opinion in Rheumatology
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