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Abnormal uterine bleeding

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https://www.readbyqxmd.com/read/29454147/factors-associated-with-malignancy-in-hysteroscopically-resected-endometrial-polyps-a-systematic-review-and-meta-analysis
#1
Lizandra M Paravidine Sasaki, Keitty R C Andrade, Ana Claudia Morais Godoy Figueiredo, Miriam da S Wanderley, Maurício G Pereira
The objective of our study was to estimate the frequency of pre-malignant and malignant lesions in endometrial polyps and to evaluate associated clinical and demographic factors. A literature search was performed in major databases and the gray literature using the terms polyps OR endometrial polyp AND endometrial neoplasms OR endometrial cancer OR endometrial hyperplasia OR malignan*. Studies describing the frequency of pre-malignant and malignant lesions in endometrial polyps and any clinical or demographic factors associated with malignant lesions extracted using hysteroscopy were considered eligible...
February 14, 2018: Journal of Minimally Invasive Gynecology
https://www.readbyqxmd.com/read/29454033/cause-or-coincidence-spontaneous-hematometra-in-young-women-on-depomedroxyprogesterone-acetate-a-small-case-series
#2
Julie G Thorne, Elizabeth H Russell, Danielle Rumbolt, Mary Anne Jamieson
BACKGROUND: Abdominal pain, secondary amenorrhea and abnormal uterine bleeding (AUB) are common gynecologic presentations in adolescence. Rarely this can be associated with an acquired hematometra. Hematometra is a condition of retained blood or clot within the uterus. High dose progestogenic agents in this age group have been implicated in the accumulation of a hematometra without other explanation. CASES: We present 4 cases of hematometra following depomedroxyprogesterone acetate (DMPA) therapy in previously menstruating adolescents...
February 14, 2018: Journal of Pediatric and Adolescent Gynecology
https://www.readbyqxmd.com/read/29432990/a-new-method-using-a-foley-catheter-to-locate-the-diverticulum-in-laparoscopic-repair-of-uterine-cesarean-scar-defects
#3
Wancheng Zhao, Guipeng Liu, Qing Yang, Chunmei Zhang
OBJECTIVE(S): To introduce a new method using a Foley catheter to locate the diverticulum in laparoscopic repair of uterine cesarean scar defect (CSD), and to evaluate the gynecological outcomes and prognosis of this new procedure. STUDY DESIGN: Twelve patients with abnormal uterine bleeding or future fertility requirements opted for the laparoscopic repair of CSD. Then we present a series of photographic images before and after placement of the Foley catheter, and their clinical data to evaluate this new surgical technique...
February 8, 2018: European Journal of Obstetrics, Gynecology, and Reproductive Biology
https://www.readbyqxmd.com/read/29422425/utility-of-clinical-parameters-and-multiparametric-mri-as-predictive-factors-for-differentiating-uterine-sarcoma-from-atypical-leiomyoma
#4
Qiu Bi, Zhibo Xiao, Fajin Lv, Yao Liu, Chunxia Zou, Yiqing Shen
OBJECTIVES: The objective of this study was to find clinical parameters and qualitative and quantitative magnetic resonance imaging (MRI) features for differentiating uterine sarcoma from atypical leiomyoma (ALM) preoperatively and to calculate predictive values for uterine sarcoma. MATERIALS AND METHODS: Data from 60 patients with uterine sarcoma and 88 patients with ALM confirmed by surgery and pathology were collected. Clinical parameters, qualitative MRI features, diffusion-weighted imaging with apparent diffusion coefficient values, and quantitative parameters of dynamic contrast-enhanced MRI of these two tumor types were compared...
February 5, 2018: Academic Radiology
https://www.readbyqxmd.com/read/29420395/ulipristal-acetate-for-treatment-of-symptomatic-uterine-leiomyomas-a-randomized-controlled-trial
#5
James A Simon, William Catherino, James H Segars, Rick E Blakesley, Anna Chan, Vilma Sniukiene, Ayman Al-Hendy
OBJECTIVE: To assess efficacy and tolerability of ulipristal acetate, a selective progesterone receptor modulator, for treatment of symptomatic uterine leiomyomas. METHODS: This phase 3, double-blind, placebo-controlled study enrolled premenopausal women (aged 18-50 years) with abnormal uterine bleeding, one or more discrete leiomyomas, and uterine size 20 weeks of gestation or less. Patients were randomized 1:1:1 to 5 mg ulipristal, 10 mg ulipristal, or placebo once daily for 12 weeks followed by 12-week drug-free follow-up...
February 5, 2018: Obstetrics and Gynecology
https://www.readbyqxmd.com/read/29391675/use-of-hysteroscopy-in-abnormal-uterine-bleeding-an-edge-over-histopathological-examination
#6
Parul Sinha, Nidhi Yadav, Uma Gupta
Purpose of the Study: To assess the efficacy of hysteroscopy in diagnosis of AUB. Method: A total of 56 women in reproductive and peri-menopausal age group (20-50 years) with complaints of abnormal uterine bleeding were enrolled in the study. All the patients underwent hysteroscopic examination followed by biopsy/histopathological evaluation. Hysteroscopic findings were compared against histopathological findings. Sensitivity, specificity, PPV, NPV and accuracy of hysteroscopy were calculated...
February 2018: Journal of Obstetrics and Gynaecology of India
https://www.readbyqxmd.com/read/29390219/-combined-treatment-of-endometriosis-radical-yet-gentle
#7
Ibrahim Alkatout, Thilo Wedel, Nicolai Maass
Endometriosis is the second most common benign female genital disease after uterine myoma. This review discusses the management of individual patients. This should take into account the severity of the disease and whether the patient desires to have children. Particular emphasis is laid on the anatomical intersections which, when injured, can lead to persistent damage of the anterior, middle or posterior compartment and are not infrequently the cause of urological and urogynaecological follow-up measures. Typical symptoms of endometriosis include chronic pelvic pain, subfertility, dysmenorrhoea, deep dyspareunia, cyclical bowel or bladder symptoms (e...
February 2018: Aktuelle Urologie
https://www.readbyqxmd.com/read/29385977/abnormal-uterine-bleeding-managing-endometrial-dysfunction-and-leiomyomas
#8
Annabelle Brennan, Martha Hickey
Abnormal uterine bleeding refers to any change in the regularity, frequency, heaviness or length of menstruation. There are several potential causes for bleeding disturbance, the two most common being primary endometrial dysfunction and fibroids. Management of abnormal uterine bleeding involves both medical and surgical options and will largely depend on a patient's fertility plans. The use of levonorgestrel-releasing intrauterine devices for heavy menstrual bleeding is increasing in Australia, and they are considered first-line medical management for women accepting of hormonal therapies...
February 5, 2018: Medical Journal of Australia
https://www.readbyqxmd.com/read/29384976/radiofrequency-induced-endometrial-ablation-for-the-treatment-of-postpartum-hemorrhage-after-vaginal-delivery-case-report
#9
Zhang Wangping, Wu Hanbing
RATIONALE: Postpartum hemorrhage is a common complication and difficult problem in obstetrics. Radiofrequency-induced endometrial ablation (RFIEA) widely used in abnormal uterine bleeding and achieved good effects. This article will investigate the effect of RFIEA for treatment of postpartum hemorrhage. PATIENTS CONCERNS: A 26-year-old healthy full-term parturient woman presented with postpartum hemorrhage after vaginal delivery for 11 hours, who was ready to emergency surgery (hysterectomy) 7 hours after inserting an intrauterine balloon into uterine cavity...
December 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29379246/endovascular-uterine-artery-interventions
#10
Chandan J Das, Deepak Rathinam, Smita Manchanda, D N Srivastava
Percutaneous vascular embolization plays an important role in the management of various gynecologic and obstetric abnormalities. Transcatheter embolization is a minimally invasive alternative procedure to surgery with reduced morbidity and mortality, and preserves the patient's future fertility potential. The clinical indications for transcatheter embolization are much broader and include many benign gynecologic conditions, such as fibroid, adenomyosis, and arteriovenous malformations (AVMs), as well as intractable bleeding due to inoperable advanced-stage malignancies...
October 2017: Indian Journal of Radiology & Imaging
https://www.readbyqxmd.com/read/29376235/-study-on-the-mechanism-of-bushen-culuan-chongji-treating-kidney-deficiency-and-blood-stasis-in-ovulatory-dysfunctional-infertility
#11
Kun Ma, Min Li
Kidney deficiency and blood stasis is the main cause of ovulatory dysfunctional infertility. Kidney deficiency is the main pathological mechanism. Blood stasis is the main pathological manifestation, and it is an important factor throughout. Bushen Culuan Chongji is under the guidance of traditional Chinese medicine(TCM) theory, previous years of clinical experience, combined with the etiology and pathogenesis of anovulatory infertility and modern pharmacological research results, selected, not only maintains the TCM syndrome differentiation and different diseases features, but also reflects the superiority of the combination of disease...
December 2017: Zhongguo Zhong Yao za Zhi, Zhongguo Zhongyao Zazhi, China Journal of Chinese Materia Medica
https://www.readbyqxmd.com/read/29374620/pain-is-an-independent-risk-factor-for-failed-global-endometrial-ablation
#12
Meagan S Cramer, Jordan S Klebanoff, Matthew K Hoffman
STUDY OBJECTIVE: To determine if pain, as part of an indication for global endometrial ablation, is an independent risk factor for failure. DESIGN: Retrospective cohort study. DESIGN CLASSIFICATION: Canadian Task Force classification II-2 SETTING: Academic-affiliated community hospital PATIENTS: Women undergoing global endometrial ablation (Radiofrequency Ablation (RFA), Hydrothermablation (HTA), or Uterine Balloon Ablation (UBA)) from January 2003 to December 2015...
January 25, 2018: Journal of Minimally Invasive Gynecology
https://www.readbyqxmd.com/read/29372157/clinical-experience-of-long-term-use-of-dienogest-after-surgery-for-ovarian-endometrioma
#13
Anjali Chandra, A Mi Rho, Kyungah Jeong, Taeri Yu, Ji Hyun Jeon, So Yun Park, Sa Ra Lee, Hye-Sung Moon, Hye Won Chung
Objective: Endometriosis is a common and recurring gynecologic disease which have afflicting females of reproductive age. We investigated the efficacy of long-term, post-operative use of dienogest for ovarian endometrioma. Methods: We studied 203 patients who had undergone laparoscopic or robotic surgery for ovarian endometrioma, and were administrated dienogest 2 mg/day beginning in July of 2013, and continuing. We evaluated side effects of dienogest and ultrasonography was performed every 6 months to detect potential recurrence of endometrioma (2 cm) in these post-surgical patients...
January 2018: Obstetrics & Gynecology Science
https://www.readbyqxmd.com/read/29369919/actinomycotic-endometritis
#14
Andres G Chiesa-Vottero
Seven cases of actinomycotic endometritis were identified among 28,906 endometrial biopsies performed in the last 10 yr. The patients' ages ranged from 44 to 85 yr old. An intrauterine device was in place from 7 to 44 yr. The reasons to perform the biopsies included abnormal uterine bleeding, malodor, prolapse, pelvic inflammatory disease, and suspicion of metastatic uterine sarcoma. Definitive identification of Actinomyces israelii by culture was obtained in 1 case only. Gram, Gomori methenamine silver, and Fite stains were useful in the differential diagnosis with pseudoactinomycotic granules, Nocardia, fungi, and other bacteria...
January 24, 2018: International Journal of Gynecological Pathology
https://www.readbyqxmd.com/read/29355897/the-need-for-further-surgical-intervention-following-primary-hysteroscopic-morcellation-of-submucosal-leiomyomas-in-women-with-abnormal-uterine-bleeding
#15
Sarah Maheux-Lacroix, Jennifer Mennen, Amy Arnold, Aaron Budden, Erin Nesbitt-Hawes, HaRyun Won, Jason Abbott
BACKGROUND: Intrauterine hysteroscopic morcellators have been studied as an alternative method for removing submucosal leiomyomas. AIMS: To assess the long-term efficacy of hysteroscopic morcellation of submucosal leiomyomas in women with abnormal uterine bleeding (AUB). MATERIALS AND METHODS: We conducted a prospective cohort study including all women with AUB who underwent a hysteroscopic resection with mechanical morcellation of a benign submucosal leiomyoma confirmed at histopathology...
January 22, 2018: Australian & New Zealand Journal of Obstetrics & Gynaecology
https://www.readbyqxmd.com/read/29347814/-customization-of-hormonal-contraception
#16
Vincenzo DE Leo, Antonio Cianci, Costantino DI Carlo, Valentina Cappelli, Franca Fruzzetti
In the last few years new oral contraceptives have been marketed showing a better safety profile for women. They are the result of important changes made to the old compounds. As far as the estrogenic component, with the aim of decreasing side effects, the dose of ethinyl estradiol has been reduced and synthetic estrogens have been replaced by natural estradiol, further improving the safety profile. Also the progestin component in the last years has been changed in terms of dose, endocrine and metabolic characteristics...
February 2018: Minerva Ginecologica
https://www.readbyqxmd.com/read/29319588/abnormal-uterine-bleeding-treatment-options
#17
Erica Oberman, Valentina Rodriguez-Triana
Abnormal uterine bleeding is one of the most common reasons for outpatient gynecologic visits. Proper evaluation and diagnosis is essential and allows the clinician to present individualized treatment options to their patients.
March 2018: Clinical Obstetrics and Gynecology
https://www.readbyqxmd.com/read/29288653/long-term-outcomes-after-elective-sterilization-procedures-a-comparative-retrospective-cohort-study-of-medicaid-patients
#18
Rachel Steward, Patricia Carney, Amy Law, Lin Xie, Yuexi Wang, Huseyin Yuce
OBJECTIVES: Compare the long-term outcomes, including hysterectomy, chronic pelvic pain (CPP), and abnormal uterine bleeding (AUB) in women post-hysteroscopic sterilization (HS) and laparoscopic tubal ligation (TL) in the Medicaid population. STUDY DESIGN: Retrospective observational cohort analysis using data from the US Medicaid Analytic Extracts (MAX) Encounters database. Women aged 18 to 49years with at least one claim for HS (n=3929) or TL (n=10,875) between July 1, 2009, through December 31, 2010 were included...
December 27, 2017: Contraception
https://www.readbyqxmd.com/read/29288067/nationwide-trends-in-the-utilization-of-and-payments-for-hysterectomy-in-the-united-states-among-commercially-insured-women
#19
Daniel M Morgan, Neil S Kamdar, Carolyn W Swenson, Emily K Kobernik, Anne G Sammarco, Brahmajee Nallamothu
BACKGROUND: Laparotomy followed by inpatient hospitalization has traditionally been the most common surgical care for hysterectomy. The financial implications of the increased use of laparoscopy and outpatient hysterectomy are unknown. OBJECTIVES: To quantify the increasing use of laparoscopy and outpatient hysterectomy and to describe the financial implications among women with commercially based insurance in the United States. STUDY DESIGN: Hysterectomies between 2010 and 2013 were identified in the Health Care Cost Institute, a national dataset with inpatient and outpatient private insurance claims for more than 25 million women...
December 26, 2017: American Journal of Obstetrics and Gynecology
https://www.readbyqxmd.com/read/29241597/understanding-patient-preference-in-female-pelvic-imaging-transvaginal-ultrasound-and-mri
#20
Michelle D Sakala, Ruth C Carlos, Mishal Mendiratta-Lala, Elisabeth H Quint, Katherine E Maturen
RATIONALE AND OBJECTIVES: Women with pelvic pain or abnormal uterine bleeding may undergo diagnostic imaging. This study evaluates patient experience in transvaginal ultrasound (TVUS) and magnetic resonance imaging (MRI) and explores correlations between preference and symptom severity. MATERIALS AND METHODS: Institutional review board approval was obtained for this Health Insurance Portability and Accountability Act-compliant prospective study. Fifty premenopausal women with pelvic symptoms evaluated by recent TVUS and MRI and without history of gynecologic cancer or hysterectomy were included...
December 11, 2017: Academic Radiology
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