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Aub cause

Richard L Jantz, Lee Meadows Jantz
Secular changes in stature, weight, or other components of the body that can be obtained from historical records have been extensively studied. Cranial change has been central to anthropology for more than a century, but the focus has normally been on change measured in centuries or millennia. Cranial change measured in decades, normally considered to result from plastic response to the environment, has been less studied. This article reports on change in cranial vault dimensions in white Americans. Variables were glabello-occipital length (GOL), basion-bregma height (BBH), basion-nasion length (BNL), maximum cranial breadth (XCB), and biauricular breadth (AUB)...
January 2016: Human Biology
Yael Pecchioli, Lamide Oyewumi, Lisa M Allen, Sari Kives
STUDY OBJECTIVE: Despite the fact that most cases of abnormal uterine bleeding (AUB) in adolescence are due to an immature hypothalamic-pituitary-ovarian axis (HPO), the current approach to investigating adolescents presenting with AUB often includes pelvic ultrasound to exclude rare structural causes. The aim of this study was to determine whether an ultrasound ordered for the investigation of AUB in adolescents detects any significant anatomic pathology or alters diagnosis and management...
October 6, 2016: Journal of Pediatric and Adolescent Gynecology
Megan R Billow, Sherif A El-Nashar
Abnormal uterine bleeding (AUB) is a common problem that negatively impacts a woman's health-related quality of life and activity. Initial medical treatment includes hormonal and nonhormonal medications. If bleeding persists and no structural abnormalities are present, a repeat trial of medical therapy, a levonorgestrel intrauterine system, or an endometrial ablation can be used dependent on future fertility wishes. The levonorgestrel intrauterine system and endometrial ablation are effective, less invasive, and safe alternatives to a hysterectomy in women with AUB...
September 2016: Obstetrics and Gynecology Clinics of North America
Janu Mangala Kanthi, Chithra Remadevi, Sudha Sumathy, Deepti Sharma, Sarala Sreedhar, Amrutha Jose
INTRODUCTION: Endometrial polyp is one of the common causes of Abnormal Uterine Bleeding (AUB) in the reproductive age group as well as postmenopausal age group. AIM: To study the clinical features of endometrial polyp and the safety and feasibility of blind polypectomy following diagnostic hysteroscopy. MATERIALS AND METHODS: Total of 256 women who were diagnosed to have endometrial polyp by transvaginal ultrasound and underwent diagnostic hysteroscopy and blind polypectomy by simple avulsion in the period of January 2008 to December 2014 were included in our study...
June 2016: Journal of Clinical and Diagnostic Research: JCDR
Bharat Talukdar, Sangita Mahela
BACKGROUND: Abnormal uterine bleeding (AUB) is a frequently encountered gynecologic complaint in perimenopausal woman and also the most common cause of hysterectomy in this age group. OBJECTIVE: Evaluation of various clinical presentations of perimenopausal AUB and it is ultrasonographic and histopathological correlation of hysterectomy specimens. MATERIALS AND METHODS: This study was carried out in the Department of Obstetrics and Gynaecology among perimenopausal women who underwent hysterectomy for AUB...
April 2016: Journal of Mid-life Health
Sergei S Ryazansky, Alexei A Kotov, Mikhail V Kibanov, Natalia V Akulenko, Alina P Korbut, Sergei A Lavrov, Vladimir A Gvozdev, Ludmila V Olenina
Germline-specific RNA helicase Spindle-E (Spn-E) is known to be essential for piRNA silencing in Drosophila that takes place mainly in the perinuclear nuage granules. Loss-of-function spn-E mutations lead to tandem Stellate genes derepression in the testes and retrotransposon mobilization in the ovaries. However, Spn-E functions in the piRNA pathway are still obscure. Analysis of total library of short RNAs from the testes of spn-E heterozygous flies revealed the presence of abundant piRNA ping-pong pairs originating from Su(Ste) transcripts...
September 2016: European Journal of Cell Biology
Lorenzo Sabbioni, Isabella Zanetti, Cinzia Orlandini, Felice Petraglia, Stefano Luisi
Abnormal uterine bleeding (AUB) is one of the commonest health problems encountered by women and a frequent phenomenon during menopausal transition. The clinical management of AUB must follow a standardized classification system to obtain the better diagnostic pathway and the optimal therapy. The PALM-COEIN classification system has been approved by the International Federation of Gynecology and Obstetrics (FIGO); it recognizes structural causes of AUB, which can be measured visually with imaging techniques or histopathology, and non- structural entities such as coagulopathies, ovulatory dysfunctions, endometrial and iatrogenic causes and disorders not yet classified...
June 10, 2016: Minerva Ginecologica
Morris Wortman
Endometrial polyps (EPs) are a common cause of abnormal uterine bleeding (AUB) in perimenopausal and postmenopausal women and are typically suggested by a screening transvaginal ultrasound. In addition, the increasing use of pelvic imaging often discloses asymptomatic EPs. In the past, saline infusion sonography (SIS) has been advocated in order to triage patients to undergo a blind curettage or a diagnostic or operative hysteroscopy. The introduction of small diameter hysteroscopes and resectoscopes-often no larger than a SIS catheter-now allows most women with abnormal ultrasound findings to undergo a single-stage "see-and-treat" hysteroscopy for the management of endometrial polyps...
April 2016: Surgical Technology International
Emrah Töz, Muzaffer Sancı, Aykut Özcan, Emrah Beyan, Abdurrahman H İnan
OBJECTIVE: To compare classic terminology and the PALM-COEIN (polyp, adenomyosis, leiomyoma, malignancy and hyperplasia, coagulopathy, ovulatory disorders, endometrium, iatrogenic, and not classified) classification system among women who underwent surgery for abnormal uterine bleeding (AUB), and to subclassify the components of the PALM group for future studies. METHODS: In a retrospective study, data were obtained for nonpregnant women aged 18-55years who underwent hysterectomy, myomectomy, or polypectomy for AUB at a center in Turkey in 2014...
June 2016: International Journal of Gynaecology and Obstetrics
Frederick Schatz, Ozlem Guzeloglu-Kayisli, Sefa Arlier, Umit A Kayisli, Charles J Lockwood
BACKGROUND: Human pregnancy requires robust hemostasis to prevent hemorrhage during extravillous trophoblast (EVT) invasion of the decidualized endometrium, modification of spiral arteries and post-partum processes. However, decidual hemorrhage (abruption) can occur throughout pregnancy from poorly transformed spiral arteries, causing fetal death or spontaneous preterm birth (PTB), or it can promote the aberrant placentation observed in intrauterine growth restriction (IUGR) and pre-eclampsia; all leading causes of perinatal or maternal morbidity and mortality...
June 2016: Human Reproduction Update
Lucy Whitaker, Hilary O D Critchley
Abnormal uterine bleeding (AUB) is a common and debilitating condition with high direct and indirect costs. AUB frequently co-exists with fibroids, but the relationship between the two remains incompletely understood and in many women the identification of fibroids may be incidental to a menstrual bleeding complaint. A structured approach for establishing the cause using the Fédération International de Gynécologie et d'Obstétrique (FIGO) PALM-COEIN (Polyp, Adenomyosis, Leiomyoma, Malignancy (and hyperplasia), Coagulopathy, Ovulatory disorders, Endometrial, Iatrogenic and Not otherwise classified) classification system will facilitate accurate diagnosis and inform treatment options...
July 2016: Best Practice & Research. Clinical Obstetrics & Gynaecology
Laurence Toqué, Antoine Hamy, Jean-Francois Hamel, Elodie Cesbron, Pauline Hulo, Solen Robert, Christophe Aube, Emilie Lermite, Aurélien Venara
OBJECTIVE: Splanchnic vein thrombosis (SVT) is a potentially severe complication of pancreatitis. The aim of this single-center, retrospective cohort study was to investigate the incidence of SVT and to determine the connected risk factors. METHODS: All consecutive patients with acute pancreatitis (AP) managed in our hospital were included. The primary outcome was the occurrence of SVT and data was collected in accordance with Ranson's criteria. RESULTS: A total of 318 patients were included, of whom 124 (39...
December 2015: Journal of Digestive Diseases
Ozlem Guzeloglu Kayisli, Umit A Kayisli, Murat Basar, Nihan Semerci, Frederick Schatz, Charles J Lockwood
Use of long-acting progestin only contraceptives (LAPCs) offers a discrete and highly effective family planning method. Abnormal uterine bleeding (AUB) is the major side effect of, and cause for, discontinuation of LAPCs. The endometria of LAPC-treated women display abnormally enlarged, fragile blood vessels, decreased endometrial blood flow and oxidative stress. To understanding to mechanisms underlying AUB, we propose to identify LAPC-modulated unique gene cluster(s) in human endometrial stromal cells (HESCs)...
2015: PloS One
Sławomir Woźniak
Endometrial polyps and submucosal fibroids are common causes of abnormal uterine bleeding (AUB) and less commonly infertility. The prevalence of such intrauterine lesions increases with age during the reproductive years, and usually decreases after menopause. The first-line imaging examination in the diagnosis of endometrial polyps as well as submucosal fibroidsis ultrasound, but its accuracy is not obvious. Elastography is an ultrasound-based imaging modality that is used to assess the stiffness of examined tissues...
June 2015: Przeglad Menopauzalny, Menopause Review
T Justin Clark, Lee J Middleton, Natalie Am Cooper, Lavanya Diwakar, Elaine Denny, Paul Smith, Laura Gennard, Lynda Stobert, Tracy E Roberts, Versha Cheed, Tracey Bingham, Sue Jowett, Elizabeth Brettell, Mary Connor, Sian E Jones, Jane P Daniels
BACKGROUND: Uterine polyps cause abnormal bleeding in women and conventional practice is to remove them in hospital under general anaesthetic. Advances in technology make it possible to perform polypectomy in an outpatient setting, yet evidence of effectiveness is limited. OBJECTIVES: To test the hypothesis that in women with abnormal uterine bleeding (AUB) associated with benign uterine polyp(s), outpatient polyp treatment achieved as good, or no more than 25% worse, alleviation of bleeding symptoms at 6 months compared with standard inpatient treatment...
July 2015: Health Technology Assessment: HTA
Afsaneh Tehranian, Leila Bayani, Somayesadat Heidary, Hadis Rastad, Akram Rahimi, Ladan Hosseini
BACKGROUND: AUB is a common cause of women's referring to gynecologists. Although hysteroscopy is known as the gold standard technique for diagnosing the cause of AUB, sonohysterography is less invasive, and it is performed by general gynecologists. The purpose of this study was to evaluate the diagnostic performance of sonohysterography compared to the results of the endometrial biopsy, guided by hysteroscopy in premenopausal women with AUB. METHODS: This cross- sectional Study was conducted at the gynecological clinic of Roointan -Arash women's Hospital from February 2011 to February 2012...
2015: Medical Journal of the Islamic Republic of Iran
S Parveen, S A Azad, J Mohammad, S Haque, R S Shanta, S M Rahman
This prospective randomized study was carried out in the department of Radiology and Imaging in collaboration with the department of Obstetrics and Gynecology of Bangabandhu Sheikh Mujib Medical University (BSMMU), Shahbag and Dhaka Medical College Hospital (DMCH) during the period of January 2003 to December 2004. The aim of this study was to establish sonohyterography as a sensitive tool and superior to Transvaginal Sonography (TVS) for detection of endometrial pathology in women with abnormal uterine bleeding (AUB) and its validity by determining sensitivity, specificity, accuracy, positive predictive value and negative predictive value...
April 2014: Bangladesh Medical Research Council Bulletin
Philippe Laberge, Nicholas Leyland, Ally Murji, Claude Fortin, Paul Martyn, George Vilos, Nicholas Leyland, Wendy Wolfman, Catherine Allaire, Alaa Awadalla, Sheila Dunn, Mark Heywood, Madeleine Lemyre, Violaine Marcoux, Frank Potestio, David Rittenberg, Sukhbir Singh, Grace Yeung
BACKGROUND: Abnormal uterine bleeding (AUB) is the direct cause of a significant health care burden for women, their families, and society as a whole. Up to 30% of women will seek medical assistance for the problem during their reproductive years. OBJECTIVE: To provide current evidence-based guidelines on the techniques and technologies used in endometrial ablation (EA), a minimally invasive technique for the management of AUB of benign origin. METHODS: Members of the guideline committee were selected on the basis of individual expertise to represent a range of practical and academic experience in terms of both location in Canada and type of practice, as well as subspecialty expertise and general background in gynaecology...
April 2015: Journal of Obstetrics and Gynaecology Canada: JOGC, Journal D'obstétrique et Gynécologie du Canada: JOGC
Lucia K Gonzales, Margaret A Delmastro, Denise M Boyd, Melvyn L Sterling, Patricia A Aube, Rosemary N Le, Lisa Traucht, Leonida R Quinal, Jane M Georges, Dale N Glaser
In palliative medicine, constipation is the third most common symptom after pain and anorexia, causing some patients to discontinue opioid therapy. Women experience higher incidence of constipation than men. The prevalence of infrequent bowel movements (<3 times/wk) and adherence to an established bowel regimen among women receiving opioids were studied. Referral to the palliative care team decreased the prevalence of infrequent bowel movements from 72% to 45%, and algorithm adherence increased from 38% to 78%...
August 2016: American Journal of Hospice & Palliative Care
Weili Zhu, Jiaping Mao, Xia Liu
OBJECTIVE: To explore the feasibility, safety and effectiveness of treatment by Novasure system in abnormal uterine bleeding caused by endometrial polyps (AUB-P) or uterine leiomyomas up to 3 cm (AUB-LSM). METHODS: From June 2011 to June 2012, 30 women with abnormal uterine bleeding caused by AUB-P and AUB-LSM were treated by NoveSure system. The clinical efficacies and complications were followed up at months 1, 3, 6, 12. RESULTS: All operations were completed successfully...
February 17, 2015: Zhonghua Yi Xue za Zhi [Chinese medical journal]
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