keyword
MENU ▼
Read by QxMD icon Read
search

adams

keyword
https://www.readbyqxmd.com/read/29236110/simultaneous-monitoring-of-different-vitrification-solution-components-permeating-into-tissues
#1
Andrés Vásquez-Rivera, Kim K Sommer, Harriëtte Oldenhof, Adam Z Higgins, Kelvin G M Brockbank, Andres Hilfiker, Willem F Wolkers
Cryopreservation can be used for long-term preservation of tissues and organs. It relies on using complex mixtures of cryoprotective agents (CPAs) to reduce the damaging effects of freezing, but care should be taken to avoid toxic effects of CPAs themselves. In order to rationally design cryopreservation strategies for tissues, it is important to precisely determine permeation kinetics of the protectants that are used to ensure maximum permeation, while minimizing the exposure time and toxicity effects. This is particularly challenging with protectant solutions consisting of multiple components each with different physical properties and diffusing at a different rate...
December 13, 2017: Analyst
https://www.readbyqxmd.com/read/29235915/social-bots-human-like-by-means-of-human-control
#2
Christian Grimme, Mike Preuss, Lena Adam, Heike Trautmann
Social bots are currently regarded an influential but also somewhat mysterious factor in public discourse and opinion making. They are considered to be capable of massively distributing propaganda in social and online media, and their application is even suspected to be partly responsible for recent election results. Astonishingly, the term social bot is not well defined and different scientific disciplines use divergent definitions. This work starts with a balanced definition attempt, before providing an overview of how social bots actually work (taking the example of Twitter) and what their current technical limitations are...
December 2017: Big Data
https://www.readbyqxmd.com/read/29235768/optimism-rings-in-the-new-year
#3
EDITORIAL
Damon Adams
No abstract text is available yet for this article.
January 2017: Dentistry Today
https://www.readbyqxmd.com/read/29235751/the-innovation-engine
#4
Damon Adams
No abstract text is available yet for this article.
February 2017: Dentistry Today
https://www.readbyqxmd.com/read/29235462/atomic-resolution-three-dimensional-hydration-structures-on-a-heterogeneously-charged-surface
#5
Kenichi Umeda, Lidija Zivanovic, Kei Kobayashi, Juha Ritala, Hiroaki Kominami, Peter Spijker, Adam S Foster, Hirofumi Yamada
Local hydration structures at the solid-liquid interface around boundary edges on heterostructures are key to an atomic-level understanding of various physical, chemical and biological processes. Recently, we succeeded in visualising atomic-scale three-dimensional hydration structures by using ultra-low noise frequency-modulation atomic force microscopy. However, the time-consuming three-dimensional-map measurements on uneven heterogeneous surfaces have not been achieved due to experimental difficulties, to the best of our knowledge...
December 13, 2017: Nature Communications
https://www.readbyqxmd.com/read/29235440/leveraging-multi-layer-imager-detector-design-to-improve-low-dose-performance-for-megavoltage-cone-beam-computed-tomography
#6
Yue-Houng Hu, Joerg Rottmann, Rony Fueglistaller, Marios E Myronakis, Adam Wang, Pascal Huber, Daniel Shedlock, Daniel Morf, Paul Baturin, Josh M Star-Lack, Ross I Berbeco
While megavoltage (MV) cone-beam computed tomography (CBCT) using an electronic portal imaging device (EPID) provides many advantages over kilovoltage (kV) CBCT, clinical adoption is limited by its high doses. Multi-layer imager (MLI) EPIDs increase DQE(0) while maintaining high resolution. However, even well-designed, high-performance MLIs suffer from increased electronic noise from each readout, degrading low-dose image quality. To improve low-dose performance, shift-and-bin addition (ShiBA) imaging is proposed, leveraging the unique architecture of the MLI...
December 13, 2017: Physics in Medicine and Biology
https://www.readbyqxmd.com/read/29235436/bioprosthetic-aortic-valve-leaflet-thrombosis-detected-by-multidetector-computed-tomography-is-associated-with-adverse-cerebrovascular-events-a-meta-analysis-of-observational-studies
#7
Hashrul N Rashid, Robert P Gooley, Nitesh Nerlekar, Abdul R Ihdayhid, Liam M McCormick, Arthur Nasis, James D Cameron, Adam J Brown
AIMS: Leaflet thrombosis (LT) has become increasingly recognised following transcatheter and surgical aortic ABV replacement and can be reliably identified by MDCT. However, it is ongoing debate whether MDCT-defined LT is associated with adverse cerebrovascular outcomes. We performed a systematic review and meta-analysis to assess the incidence and clinical outcomes associated with multidetector computed tomography (MDCT)-defined leaflet thrombosis following aortic bioprosthetic valve (ABV) replacement...
December 12, 2017: EuroIntervention
https://www.readbyqxmd.com/read/29235325/interest-in-implant-dentistry-grows
#8
Damon Adams
No abstract text is available yet for this article.
March 2017: Dentistry Today
https://www.readbyqxmd.com/read/29235307/oral-cancer-awareness-month
#9
EDITORIAL
Damon Adams
No abstract text is available yet for this article.
April 2017: Dentistry Today
https://www.readbyqxmd.com/read/29235208/optical-coherence-tomography-for-assessment-of-epithelialization-in-a-human-ex-vivo-wound-model
#10
George D Glinos, Sebastian H Verne, Adam S Aldahan, Liang Liang, Keyvan Nouri, Sharon Elliot, Marilyn Glassberg, Delia Cabrera DeBuc, Tulay Koru-Sengul, Marjana Tomic-Canic, Irena Pastar
The ex vivo human skin wound model is a widely accepted model to study wound epithelialization. Due to a lack of animal models that fully replicate human conditions, the ex vivo model is a valuable tool to study mechanisms of wound re-epithelialization, as well as for pre-clinical testing of novel therapeutics. The current standard for assessment of wound healing in this model is histomorphometric analysis, which is labor intensive, time consuming, and requires multiple biological and technical replicates in addition to assessment of different time points...
December 13, 2017: Wound Repair and Regeneration
https://www.readbyqxmd.com/read/29234999/prognostic-significance-of-serum-inflammatory-markers-in-gastric-cancer
#11
Arfon G M T Powell, Debora Parkinson, Neil Patel, David Chan, Adam Christian, Wyn G Lewis
BACKGROUND: The aim of this study was to assess the relative prognostic value of biomarkers to measure the systemic inflammatory response (SIR) and improve prognostic modeling in a cohort of patients undergoing potentially curative surgery for gastric adenocarcinoma. The hypothesis was that a single SIR biomarker would be associated with the most prognostic value. METHODS: Consecutive 331 patients undergoing surgery for gastric cancer between 2004 and 2016 within a regional UK cancer network were identified...
October 4, 2017: Journal of Gastrointestinal Surgery: Official Journal of the Society for Surgery of the Alimentary Tract
https://www.readbyqxmd.com/read/29234948/assessing-documentation-of-critical-imaging-result-follow-up-recommendations-in-emergency-department-discharge-instructions
#12
Anurag Gupta, Ronilda Lacson, Patricia C Balthazar, Shan Haq, Adam B Landman, Ramin Khorasani
To facilitate follow-up of critical test results across transitions in patient care settings, we implemented an electronic discharge module that enabled care providers to include follow-up recommendations in the discharge instructions. We assessed the impact of this module on documentation of follow-up recommendations for critical imaging findings in Emergency Department (ED) discharge instructions. We studied 240 patients with critical imaging findings discharged from the ED before (n = 80) and after (n = 160) implementation of the module...
December 12, 2017: Journal of Digital Imaging: the Official Journal of the Society for Computer Applications in Radiology
https://www.readbyqxmd.com/read/29234571/measurement-of-elevated-il-37-levels-in-acute-ischemic-brain-injury-a-cross-sectional-pilot-study
#13
Atif Zafar, Asad Ikram, Dinesh V Jillella, Duraisamy Kempuraj, Mohammad Moshahid Khan, Saif Bushnaq, Harold Adam, Santiago Ortega-Gutierrez, Syed A Quadri, Mudassir Farooqui, Asgar Zaheer, Enrique C Leira
Interleukin (IL)-37 is a new member of the IL-1 cytokine family with a defined role as a negative feedback inhibitor of proinflammatory responses. IL-37 has yet to be evaluated in non-immune-mediated neurological diseases, such as ischemic or hemorrhagic strokes. This study aimed to measure urine and serum IL-37 levels in patients with ischemic stroke. Twelve patients consented for our study. Two sets of serum and urine samples were obtained and analyzed, one upon admission to the hospital and the second the next morning...
October 11, 2017: Curēus
https://www.readbyqxmd.com/read/29234294/the-mark-of-the-cognitive-and-the-coupling-constitution-fallacy-a-defense-of-the-extended-mind-hypothesis
#14
REVIEW
Giulia Piredda
Clark and Chalmers (1998) introduced the extended mind hypothesis, according to which some mental states can be realized by non-biological external resources. A lively debate has flourished around this hypothesis, connected with the issues of embodiment, embeddedness, situatedness and enaction (cf. Clark, 2008; Menary, 2010; Shapiro, 2011). Two of the main criticisms addressed to the functionalist version of the extended mind thesis have been the so-called "coupling-constitution fallacy" and the alleged lack of a mark of the cognitive (Adams and Aizawa, 2001, 2005, 2009, 2010a,b)...
2017: Frontiers in Psychology
https://www.readbyqxmd.com/read/29234123/dusp1-regulates-apoptosis-and-cell-migration-but-not-the-jip1-protected-cytokine-response-during-respiratory-syncytial-virus-and-sendai-virus-infection
#15
Alexa C Robitaille, Elise Caron, Nicolas Zucchini, Espérance Mukawera, Damien Adam, Mélissa K Mariani, Anaïs Gélinas, Audray Fortin, Emmanuelle Brochiero, Nathalie Grandvaux
The host antiviral response involves the induction of interferons and proinflammatory cytokines, but also the activation of cell death pathways, including apoptosis, to limit viral replication and spreading. This host defense is strictly regulated to eliminate the infection while limiting tissue damage that is associated with virus pathogenesis. Post-translational modifications, most notably phosphorylation, are key regulators of the antiviral defense implying an important role of protein phosphatases. Here, we investigated the role of the dual-specificity phosphatase 1 (DUSP1) in the host defense against human respiratory syncytial virus (RSV), a pathogenic virus of the Pneumoviridae family, and Sendai virus (SeV), a model virus being developed as a vector for anti-RSV vaccine...
December 12, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29233930/critical-research-gaps-and-recommendations-to-inform-research-prioritisation-for-more-effective-prevention-and-improved-outcomes-in-colorectal-cancer
#16
REVIEW
Mark Lawler, Deborah Alsina, Richard A Adams, Annie S Anderson, Gina Brown, Nicola S Fearnhead, Stephen W Fenwick, Stephen P Halloran, Daniel Hochhauser, Mark A Hull, Viktor H Koelzer, Angus G K McNair, Kevin J Monahan, Inke Näthke, Christine Norton, Marco R Novelli, Robert J C Steele, Anne L Thomas, Lisa M Wilde, Richard H Wilson, Ian Tomlinson
OBJECTIVE: Colorectal cancer (CRC) leads to significant morbidity/mortality worldwide. Defining critical research gaps (RG), their prioritisation and resolution, could improve patient outcomes. DESIGN: RG analysis was conducted by a multidisciplinary panel of patients, clinicians and researchers (n=71). Eight working groups (WG) were constituted: discovery science; risk; prevention; early diagnosis and screening; pathology; curative treatment; stage IV disease; and living with and beyond CRC...
January 2018: Gut
https://www.readbyqxmd.com/read/29233922/deep-experimental-profiling-of-microrna-diversity-deployment-and-evolution-across-the-drosophila-genus
#17
Jaaved Mohammed, Alex S Flynt, Alexandra M Panzarino, Md Mosharrof Hussein Mondal, Matthew DeCruz, Adam Siepel, Eric C Lai
To assess miRNA evolution across the Drosophila genus, we analyzed several billion small RNA reads across 12 fruit fly species. These data permit comprehensive curation of species- and clade-specific variation in miRNA identity, abundance, and processing. Among well-conserved miRNAs, we observed unexpected cases of clade-specific variation in 5' end precision, occasional antisense loci, and putatively noncanonical loci. We also used strict criteria to identify a large set (649) of novel, evolutionarily restricted miRNAs...
December 12, 2017: Genome Research
https://www.readbyqxmd.com/read/29233821/activity-of-the-pi3k-%C3%AE-%C3%AE-inhibitor-duvelisib-in-a-phase-i-trial-and-preclinical-models-of-t-cell-lymphoma
#18
Steven M Horwitz, Raphael Koch, Pierluigi Porcu, Yasuhiro Oki, Alison Moskowitz, Megan Perez, Patricia Myskowski, Adam Officer, Jacob D Jaffe, Sara N Morrow, Kerstin Allen, Mark Douglas, Howard Stern, Jennifer Sweeney, Patrick Kelly, Virginia Kelly, Jon C Aster, David Weaver, Francine M Foss, David M Weinstock
Duvelisib (IPI-145) is an oral inhibitor of phosphoinositide-3-kinase (PI3K)-δ/γ isoforms currently in clinical development. PI3K-δ/γ inhibition may directly inhibit malignant T-cell growth, making Duvelisib a promising candidate for patients with peripheral (PTCL) or cutaneous (CTCL) T-cell lymphoma. Inhibition of either isoform may also contribute to clinical responses by modulating nonmalignant immune cells. We investigated these dual effects in a TCL cohort from a Phase 1, open-label study of Duvelisib in patients with relapsed or refractory PTCL [n=16] and CTCL [n=19], along with in vitro and in vivo models of TCL...
December 12, 2017: Blood
https://www.readbyqxmd.com/read/29233664/performance-of-a-prostate-cancer-genomic-classifier-in-predicting-metastasis-in-men-with-prostate-specific-antigen-persistence-postprostatectomy
#19
Daniel E Spratt, Darlene L Y Dai, Robert B Den, Patricia Troncoso, Kasra Yousefi, Ashley E Ross, Edward M Schaeffer, Zaid Haddad, Elai Davicioni, Rohit Mehra, Todd M Morgan, Walter Rayford, Firas Abdollah, Edouard Trabulsi, Mary Achim, Elsa Li Ning Tapia, Mireya Guerrero, Robert Jeffrey Karnes, Adam P Dicker, Mark A Hurwitz, Paul L Nguyen, Felix F Y Feng, Stephen J Freedland, John W Davis
BACKGROUND: Prostate cancer patients who have a detectable prostate-specific antigen (PSA) postprostatectomy may harbor pre-existing metastatic disease. To our knowledge, none of the commercially available genomic biomarkers have been investigated in such men. OBJECTIVE: To evaluate if a 22-gene genomic classifier can independently predict development of metastasis in men with PSA persistence postoperatively. DESIGN, SETTING, AND PARTICIPANTS: A multi-institutional study of 477 men who underwent radical prostatectomy (RP) between 1990 and 2015 from three academic centers...
December 9, 2017: European Urology
https://www.readbyqxmd.com/read/29233569/continuous-adductor-canal-blocks-provide-superior-ambulation-and-pain-control-compared-to-epidural-analgesia-for-primary-knee-arthroplasty-a-randomized-controlled-trial
#20
Erdan Kayupov, Kamil Okroj, Adam C Young, Mario Moric, Timothy J Luchetti, Gilat Zisman, Asokumar Buvanendran, Tad L Gerlinger, Craig J Della Valle
BACKGROUND: Adductor canal blocks (ACBs) are an alternative to femoral nerve blocks that minimize lower extremity weakness. However, it is unclear whether this block will provide analgesia that is equivalent to techniques, such as epidural analgesia. The purpose of this randomized controlled trial was to compare continuous ACBs with epidural analgesia for primary total knee arthroplasty. METHODS: Following institutional review board approval, 145 patients were randomized to 1 of 3 groups: combined spinal-epidural (CSE), spinal + continuous ACB (CACB), or general + CACB...
November 13, 2017: Journal of Arthroplasty
keyword
keyword
83369
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"