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https://www.readbyqxmd.com/read/26088557/oral-administration-of-low-dose-bisphenol-a-promotes-proliferation-of-ventral-prostate-and-upregulates-prostaglandin-d2-synthase-expression-in-adult-rats
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Jianhui Wu, Dongyan Huang, Xin Su, Han Yan, Zuyue Sun
This study aims to assess the effect of low oral dose of bisphenol A (BPA) on proliferation of ventral prostate (VP) and expression of related genes in adult rats. Three-month-old male Sprague Dawley rats were treated daily with BPA (10, 30, or 90 µg/kg, per os), 17β-estradiol (E2, 10.0 µg/kg, subcutaneously), or vehicle for 4 weeks. Treatment with 10 µg/kg BPA resulted in increased animal weight and VP epithelial height compared with the controls (p < 0.01), while such effects were less pronounced in higher BPA doses...
June 18, 2015: Toxicology and Industrial Health
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