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Lisa Philichi, Melawati Yuwono
Fecal disimpaction in the hospital setting may be necessary for a constipated child's condition to improve. This study evaluated the efficiency of 2 disimpaction therapies: nasogastric GoLYTELY (polyethylene glycol-electrolyte solution) compared with oral magnesium citrate. Retrospective chart review of 103 children was conducted to determine the time from the start of the clinic cleanout until abdominal radiograph verification of successful stool evacuation. The children were in an age range of 1-18 years, with average age of 8 years...
March 2018: Gastroenterology Nursing: the Official Journal of the Society of Gastroenterology Nurses and Associates
Rinarani M Sanghavi, Ricardo Medina-Centeno, Bradley Barth
OBJECTIVES: Colonic manometry is used frequently in children with long standing and difficult to manage constipation to aid in management decisions. Accurate analysis requires placement of the colonic manometry catheter in the colon without looping. This is technically difficult due to the long-standing nature of the constipation in most patients leading to sigmoid and other colonic redundancy. Single balloon colonoscopy has been successfully used in adult in cases of difficult colonoscopy...
March 22, 2018: Journal of Pediatric Gastroenterology and Nutrition
Kamran Ayub, Gyanprakash Ketwaroo, Suhaib Abudayyeh, Abeer Ibrahim, Rhonda A Cole, Rosetta Brumfield-Brown, Waqar A Qureshi, Linda Rabeneck, David Y Graham
OBJECTIVE: Effective screening colonoscopy depends on the quality of colon preparation. This study aimed to compare pulsed irrigation evacuation (PIE), polyethylene glycol (PEG) and sodium phosphate colon preparations. METHODS: Outpatients at a VA hospital were randomized using sealed envelopes. Preparations consisted of polyethylene glycol 4L, Fleet sodium phosphate 90 mL with four to six glasses water twice daily and 296 mL of magnesium citrate in the evening with PIE prior to colonoscopy...
December 2017: Journal of Digestive Diseases
Lisa Kunz, Debra Gillespie
Clinical practice shows that patients with constipation are more likely to have a poor bowel preparation for colonoscopy. Consequences of poor bowel preparation include missed lesions, increased complication rates, and higher costs. Research on preparing constipated patients for colonoscopy with Food and Drug Administration-approved medications is scarce. This study included 372 patients and compared the effectiveness of high-volume (4 L) polyethylene glycol solution (GoLYTELY) with low-volume (2 L) polyethylene glycol solution with ascorbate (MoviPrep) in constipated and nonconstipated adults...
September 2017: Gastroenterology Nursing: the Official Journal of the Society of Gastroenterology Nurses and Associates
Miguel Mínguez, Antonio López Higueras, Javier Júdez
OBJECTIVE: The objective of this study was to evaluate in an analytical and descriptive manner the evidence published so far on the use of polyethylene glycol (PEG), with or without electrolytes, in the management of functional constipation and the treatment of fecal impaction. METHODOLOGY: Search on MEDLINE, EMBASE and Cochrane databases until May 2016 of all publications adjusted to the following terms: constipation AND/OR fecal impaction AND (PEG OR polyethylene glycol OR macrogol OR movicol OR idralax OR miralax OR transipeg OR forlax OR golytely OR isocolan OR mulytely) NOT colonoscopy...
December 2016: Revista Española de Enfermedades Digestivas
William F Ergen, Trisha Pasricha, Francie J Hubbard, Tina Higginbotham, Tonya Givens, James C Slaughter, Keith L Obstein
BACKGROUND & AIMS: Inadequate bowel preparation is a problem frequently encountered by gastroenterologists who perform colonoscopies on hospitalized patients. A method is needed to increase the quality of bowel preparation in inpatients. An educational booklet has been shown to increase the overall quality of bowel preparation for outpatients. We performed a prospective study to evaluate the effects of an educational booklet on the quality of bowel preparation in a group of hospitalized patients...
June 2016: Clinical Gastroenterology and Hepatology
Akif Altinbaş, Barış Yilmaz, Bora Aktaş, Fuat Ekiz, Zahide Şimşek, Ömer Başar, Şahin Çoban, Osman Yüksel
BACKGROUND/AIM: Even though polyethylene glycol-electrolyte lavage (PEG-EL)-based regimes have become the gold standard in recent years, to finish drinking 4 L of PEG-EL solution can be difficult. The quality of sennoside-based bowel-cleansing regimes used in Turkey has been known for some time. Therefore, we aimed to investigate the efficacy of both bowel-cleansing regimes. MATERIALS AND METHODS: Patients over 18 years old undergoing elective colonoscopic procedures between January and March 2011 were included in the study...
2015: Turkish Journal of Medical Sciences
Michael A Darracq, Jennifer Cullen, Landen Rentmeester, F Lee Cantrell, Binh T Ly
OBJECTIVES: In December 2012, the U.S. Consumer Product Safety Commission recalled the water-absorbing toy WaterBalz after reports of small intestine obstruction after ingestion by children. Orbeez, another water-absorbing bead, remains available and is marketed as a children's toy. We sought to determine the extent to which Orbeez enlarge in various liquid media and the potential risk for bowel obstruction. METHODS: Three Orbeez beads were added to 210 mL of the following liquid media: room temperature tap water, whole milk, simulated gastric fluid, GoLytely (polyethelyelene glycol, 3350 and electrolytes), and vodka (40% ethanol by volume)...
June 2015: Pediatric Emergency Care
Ricardo A Mosquera, Mark McDonald, Cheryl Samuels
Polyethylene glycol (PEG) electrolyte solution, Golytely, is an osmotic laxative commonly used in preoperative bowel cleansing. In this case report, a 9-year-old boy developed aspiration pneumonitis following accidental infusion of PEG solution into his right lung following migration of his nasogastric tube (NGT). Hypoxemia and tachypnea without respiratory failure were observed after infusion. Because PEG is a nonabsorbable toxic material, previous case reports have advocated for the performance of bronchoalveolar lavage (BAL) in the treatment of PEG pneumonitis...
2014: Case Reports in Pediatrics
Akif Altınbas, Bora Aktas, Barıs Yılmaz, Fuat Ekiz, Murat Deveci, Omer Basar, Zahide Simsek, Sahin Coban, Yasar Tuna, Muhemmet Fatih Uyar, Osman Yuksel
BACKGROUND/AIMS: An unsuccessful colonoscopy procedure is often related to inadequate bowel cleansing. It is difficult for patients to finish the whole 4 liters of polyethylene glycol-electrolyte lavage (PEG-EL) because of its salty taste and the large quantity. Pineapple juice has been shown to be an effective agent in the dissolution of undigested food in the stomach. This study assessed the effectiveness of both 2 and 4 liters of PEG-EL in precolonoscopic bowel cleansing and the quality of colonoscopic cleaning by adding 1 liter of pineapple juice to a reduced-volume PEG-based regime...
2013: Annals of Nutrition & Metabolism
Frederick K Shieh, Naresh Gunaratnam, Sagal O Mohamud, Philip Schoenfeld
BACKGROUND: Polyethylene glycol-3350 without electrolytes (MiraLAX; Schering-Plough Healthcare Products Inc.)+a carbohydrate-electrolyte solution (Gatorade; PepsiCo Inc.)+bisacodyl is frequently used for bowel cleansing, although limited data quantifies its efficacy and safety. No prior studies have assessed this in a community setting or with PM-only dosing, which is still used frequently. AIM: To compare the frequency of excellent/good/fair/poor bowel cleansing with PM-only dosing of MiraLAX-Gatorade-bisacodyl versus 4-liter GoLytely...
November 2012: Journal of Clinical Gastroenterology
Michael C Large, Kyle J Kiriluk, G Joel DeCastro, Amit R Patel, Sandip Prasad, Gautam Jayram, Stephen G Weber, Gary D Steinberg
PURPOSE: The benefit of routine mechanical bowel preparation for patients undergoing radical cystectomy is not well established. We compared postoperative complications in patients who did or did not undergo mechanical bowel preparation before radical cystectomy. MATERIALS AND METHODS: In 2008 a single surgeon (GDS) performed open radical cystectomy with an ileal conduit or orthotopic neobladder in 105 consecutive patients with preoperative mechanical bowel preparation consisting of 4 l GoLYTELY®...
November 2012: Journal of Urology
Jason B Samarasena, V Raman Muthusamy, M Mazen Jamal
OBJECTIVES: MiraLAX with Gatorade is a low-volume bowel preparation regimen that has been used widely in community practice and is anecdotally better tolerated than Golytely. Despite its widespread use, there are little data on the efficacy and tolerability of this solution and no safety data in the literature. The primary aim of this study was to compare the efficacy, safety, and tolerability of single-dosed and split-dosed regimens of MiraLAX/Gatorade with Golytely for bowel preparation before colonoscopy...
July 2012: American Journal of Gastroenterology
B K Enestvedt, M Brian Fennerty, A Zaman, G M Eisen
BACKGROUND: In recent clinical trials (RCT) of bowel preparation, Golytely was more efficacious than MiraLAX. We hypothesised that there is a difference in adenoma detection between Golytely and MiraLAX. AIMS: To compare the adenoma detection rate (ADR) between these bowel preparations, and to identify independent predictors of bowel preparation quality and adenoma detection. METHODS: This was a post hoc analysis of an RCT that assessed efficacy and patient tolerability of Golytely vs...
October 2011: Alimentary Pharmacology & Therapeutics
Anees A Siddiqui, Steven J Fishman, Stuart B Bauer, Samuel Nurko
BACKGROUND: Antegrade continence enema (ACE) has become an important therapeutic modality in the treatment of intractable constipation and fecal incontinence. There are little data available on the long-term performance of the ACE procedure in children. METHODS: A retrospective review of patients who underwent the ACE procedure was conducted. Irrigation characteristics and complications were noted. Outcome was assessed for individual encounters based on frequency of bowel movements, incontinence, pain, and predictability...
May 2011: Journal of Pediatric Gastroenterology and Nutrition
Michael Hjelkrem, Joel Stengel, Mark Liu, David P Jones, Stephen A Harrison
BACKGROUND & AIMS: Successful colonoscopies require good bowel preparations-poor bowel preparations can increase medical costs, rates of missed lesions, and procedure duration. The combination of polyethylene glycol (PEG) 3350 without electrolytes (MiraLAX; Schering-Plough Healthcare Products, Inc, Kenilworth, NJ) and 64 oz of Gatorade (PepsiCo, Inc, Purchase, NY) has gained popularity as a bowel preparation regimen. However, the efficacy and tolerability of this approach has not been compared with standard bowel preparations in clinical trials...
April 2011: Clinical Gastroenterology and Hepatology
B K Enestvedt, M B Fennerty, G M Eisen
BACKGROUND: MiraLAX is gaining acceptance as a bowel cleanser for colonoscopy. We hypothesize that MiraLAX/Gatorade is as efficacious for bowel cleansing as Golytely and is more tolerable for patients undergoing screening colonoscopy. AIM: To compare bowel preparation scores of MiraLAX/Gatorade vs. Golytely and examine differences in patient tolerability. METHODS:   Patients undergoing screening colonoscopy were randomized to 4 L Golytely or 238 g MiraLAX in 64 ounces Golytely and four bisacodyl tablets...
January 2011: Alimentary Pharmacology & Therapeutics
J D Belsey, M Geraint, T A Dixon
It is unclear how polyethylene glycol (PEG) laxatives compare with other classes of laxative in terms of efficacy. To assess efficacy of PEG vs. placebo and active comparators in adults with non-organic constipation. Text Word searches were carried out on MEDLINE, EMBASE, CINAHL, Cochrane Central Register of Clinical Trials and Google Scholar databases covering the period January 1970 to October 2009. Search terms were (constipation) AND (randomised OR randomized) AND (PEG OR polyethylene OR macrogol OR movicol OR idrolax OR miralax OR transipeg OR forlax OR colyte OR golytely OR isocolan OR nulytely) NOT colonoscopy...
June 2010: International Journal of Clinical Practice
Hubert D Kim, Darren J Malinoski, Boris Borazjani, Madhukar S Patel, Joseph Chen, Johnathan Slone, Xuan-Mai T Nguyen, Earl Steward, Geert W Schmid-Schonbein, David B Hoyt
BACKGROUND: Recent studies suggest that intraluminal pancreatic enzymes play a major role in the initiation of the inflammatory cascade by the gut after hemorrhagic shock. Previous animal models have shown that the inhibition of enteral pancreatic enzymes with a serine protease inhibitor, nafamostat mesilate (NM), decreases leukocyte activation and transfusion requirements after hemorrhagic shock. The objective of this study was to determine whether enteroclysis with NM would improve the clinical outcomes in swine after hemorrhagic shock and intestinal hypoperfusion...
May 2010: Journal of Trauma
Ahmad H Bani-Hani, Mark P Cain, Shelly King, Richard C Rink
PURPOSE: We report the long-term effectiveness of standard tap water for Malone antegrade continence enema irrigation as well as our algorithm for managing refractory constipation/fecal incontinence in a large single institution experience. MATERIALS AND METHODS: We retrospectively reviewed the charts of 256 Malone antegrade continence enema procedures performed for chronic constipation and/or incontinence due to neuropathic bowel. Continence, type of fluid used to irrigate the colon, volume of flushes and the need for additives were recorded and a database was created...
October 2008: Journal of Urology
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