Tiziana Palmosi, Anna Maria Tolomeo, Carmine Cirillo, Debora Sandrin, Manuela Sciro, Susanna Negrisolo, Martina Todesco, Federico Caicci, Michele Santoro, Eleonora Dal Lago, Massimo Marchesan, Michele Modesti, Andrea Bagno, Filippo Romanato, Paolo Grumati, Assunta Fabozzo, Gino Gerosa
Structural cardiac lesions are often surgically repaired using prosthetic patches, which can be biological or synthetic. In the current clinical scenario, biological patches derived from the decellularization of a xenogeneic scaffold are gaining more interest as they maintain the natural architecture of the extracellular matrix (ECM) after the removal of the native cells and remnants. Once implanted in the host, these patches can induce tissue regeneration and repair, encouraging angiogenesis, migration, proliferation, and host cell differentiation...
2022: Frontiers in Bioengineering and Biotechnology