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ruptured abdominal aortic aneurysm

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https://www.readbyqxmd.com/read/28725903/suppressive-effects-of-dietary-epa-rich-fish-oil-on-the-degradation-of-elastin-fibers-in-the-aortic-wall-in-nicotine-administered-mice
#1
Hirona Kugo, Nobuhiro Zaima, Megumi Onozato, Chie Miyamoto, Keisuke Hashimoto, Kenichi Yanagimoto, Tatsuya Moriyama
Abdominal aortic aneurysm (AAA) is a vascular disease involving gradual dilation of the abdominal aorta. Recent studies suggest that nicotine, which is a primary component in cigarette smoke, is closely associated with the development and rupture of an AAA. Nicotine accelerates AAA development through the weakening of the vascular wall by increasing oxidative stress and matrix metalloproteinase (MMP)-2 expression. However, little is known about preventing the AAA induced by nicotine. A non-surgical means of preventing the weakening of the vascular wall before the onset of AAA by functional food factors would be a valuable option over surgery...
July 20, 2017: Food & Function
https://www.readbyqxmd.com/read/28723465/case-presentation-mycotic-aortic-aneurysm-and-psoas-abscess-as-a-complication-of-bacillus-calmette-gu%C3%A3-rin-instillations
#2
R Jeroen A van Moorselaar, Willem Wisselink
To prevent life-threatening aortic ruptures, it is important that primary care physicians and urologists are aware of the symptoms of a mycotic abdominal aortic aneurysm, even several months or years after bacillus Calmette-Guérin therapy.
October 2016: European Urology Focus
https://www.readbyqxmd.com/read/28720724/aortic-wall-inflammation-predicts-abdominal-aortic-aneurysm-expansion-rupture-and-need-for-surgical-repair
#3
The Ma Rs Study Investigators
Background -Ultrasmall superparamagnetic particles of iron oxide (USPIO) detect cellular inflammation on magnetic resonance imaging (MRI). In patients with abdominal aortic aneurysm, we assessed whether USPIO-enhanced MRI can predict aneurysm growth rates and clinical outcomes. Methods -In a prospective multicentre open-label cohort study, 342 patients with abdominal aortic aneurysm (diameter ≥40 mm) were classified by the presence of USPIO enhancement and were monitored with serial ultrasound and clinical follow-up for at least 2 years...
July 18, 2017: Circulation
https://www.readbyqxmd.com/read/28715511/endovascular-treatment-of-genetically-linked-aortic-diseases
#4
D Böckler, K Meisenbacher, A S Peters, C Grond-Ginsbach, M S Bischoff
BACKGROUND: The most important structural proteins of the vascular wall are collagen and elastin. Genetically linked connective tissue diseases lead to degeneration, aneurysm formation and spontaneous dissection or rupture of arteries. The most well-known are Marfan syndrome, vascular Ehlers-Danlos syndrome (type IV), Loeys-Dietz syndrome and familial aortic aneurysms and dissections. OBJECTIVE: This review article addresses the current status of endovascular treatment options for important connective tissue diseases...
2017: Gefässchirurgie: Zeitschrift Für Vaskuläre und Endovaskuläre Chirurgie
https://www.readbyqxmd.com/read/28714620/-management-of-aortic-aneurysms-in-the-endovascular-era
#5
Gino Gemayel, Michel Montessuit, Jorge Sierra, Nadia Lahlaidi Sierra, Marek Bednarkiewicz
Abdominal aortic aneurysm is a disease seen in the elderly. Without intervention, an aneurysm can rupture which leads to death in most cases. Surgical resection was the gold standard treatment for many years but since two decades, endovascular repair has surged drastically. Less invasive and morbid than open repair, this technique has significantly evolved in the recent years. Nowadays the whole aorta can be treated with endovascular techniques in expert hands. This article presents an overview of different endovascular solutions and innovations in the management of aortic aneurysms...
March 1, 2017: Revue Médicale Suisse
https://www.readbyqxmd.com/read/28706924/abdominal-aortic-aneurysm-pictorial-review-of-common-appearances-and-complications
#6
REVIEW
Yogesh Kumar, Kusum Hooda, Shuo Li, Pradeep Goyal, Nishant Gupta, Melkamu Adeb
Abdominal aortic aneurysms (AAAs) are defined as focal dilatations of the abdominal aorta that are 50% greater than the proximal normal segment or when it is more than 3 cm in maximum diameter. The early diagnosis and treatment is very important to prevent catastrophic complications. Due to its ability to assess the peri-aortic soft tissue and the exact extension of aneurysm, as well as its excellent vascular opacification and multiplanar reconstruction capabilities, computed tomography angiography (CTA) has become an integral part of the evaluation of AAA and has virtually replaced conventional angiography for the evaluation of AAA...
June 2017: Annals of Translational Medicine
https://www.readbyqxmd.com/read/28705405/-sleep-apnea-syndrome-and-abdominal-aortic-aneurysm-study-of-the-prevalence-of-sleep-apnea-syndrome-in-patients-with-aneurysm-and-research-of-association-clinical-study-on-52%C3%A2-patients
#7
J Hernigou, B Dakhil, L Belmont, J C Couffinhal, P Bagan
OBJECTIVES: Prevalence of abdominal aortic aneurysms (AAA) in Europe is between 4.1 % and 8.9 %. The risk of rupture of AAA is related to the evolution of its diameter. The role of sleep apnea (SA) remains still discussed. The objective of this study was to study the prevalence of SA in patients presenting with AAA in comparison with the general population as well as the relation between the AAA diameter and the severity of SA. MATERIALS AND METHODS: Between June 2012 and December 2014, we included all patients referred for surgical treatment of an AAA...
May 2017: J Med Vasc
https://www.readbyqxmd.com/read/28698188/a-dab2ip-genotype-sex-interaction-is-associated-with-abdominal-aortic-aneurysm-expansion
#8
Zi Ye, Erin Austin, Daniel J Schaid, Kent R Bailey, Patricia A Pellikka, Iftikhar J Kullo
A faster expansion rate of abdominal aortic aneurysm (AAA) increases the risk of rupture. Women are at higher risk of rupture than men, but the mechanisms underlying this increased risk are unknown. We investigated whether genetic variants that influence susceptibility for AAA (CDKN2A-2B, SORT1, DAB2IP, LRP1 and LDLR) are associated with AAA expansion and whether these associations differ by sex in 650 patients with AAA (mean age 70±8 years, 17% women) enrolled in the Mayo Clinic Vascular Disease Biorepository...
July 11, 2017: Journal of Investigative Medicine: the Official Publication of the American Federation for Clinical Research
https://www.readbyqxmd.com/read/28696083/artificial-neural-network-for-prediction-of-in-hospital-mortality-after-open-repair-of-ruptured-abdominal-aortic-aneurysm
#9
Thomas Luebke, Payman Majd, Spyridon N Mylonas, Jan Brunkwall
No abstract text is available yet for this article.
October 2017: Journal of Cardiovascular Surgery
https://www.readbyqxmd.com/read/28693819/haemodynamics-and-stresses-in-abdominal-aortic-aneurysms-a-fluid-structure-interaction-study-into-the-effect-of-proximal-neck-and-iliac-bifurcation-angle
#10
Corey J Drewe, Louis P Parker, Lachlan J Kelsey, Paul E Norman, Janet T Powell, Barry J Doyle
Our knowledge of how geometry influences abdominal aortic aneurysm (AAA) biomechanics is still developing. Both iliac bifurcation angle and proximal neck angle could impact the haemodynamics and stresses within AAA. Recent comparisons of the morphology of ruptured and intact AAA show that cases with large iliac bifurcation angles are less likely to rupture than those with smaller angles. We aimed to perform fluid-structure interaction (FSI) simulations on a range of idealised AAA geometries to conclusively determine the influence of proximal neck and iliac bifurcation angle on AAA wall stress and haemodynamics...
June 27, 2017: Journal of Biomechanics
https://www.readbyqxmd.com/read/28693381/a-meta-analysis-of-weekend-admission-and-surgery-for-aortic-rupture-and-dissection
#11
Hisato Takagi, Tomo Ando, Takuya Umemoto
We performed a meta-analysis to determine whether weekend admission and surgery for ruptured abdominal/thoracic aortic aneurysm (RAAA/RTAA) and acute aortic dissection (AAD) is associated with increased mortality. MEDLINE and EMBASE were searched from January 1946 to December 2016 using PubMed and OVID. Eligible studies were prospective or retrospective, comparative or cohort studies enrolling patients admitting or undergoing surgery for RAAA/RTAA/AAD and reporting mortality after weekend (including holiday) versus weekday admission/surgery...
July 1, 2017: Vascular Medicine
https://www.readbyqxmd.com/read/28691000/late-type-3b-endoleak-mimicking-type-2-endoleak-after-endovascular-aortic-aneurysm-repair
#12
Minji Cho, Chanjoong Choi, Sungsin Cho, Song-Yi Kim, Sang-Il Min, Sanghyun Ahn, Jongwon Ha, Seung-Kee Min
Endovascular abdominal aortic aneurysm (AAA) repair has been widely used for the treatment of AAA as a safe and efficient method, but endoleaks causing persistent expansion of aneurysm sac may cause aneurysmal rupture and death. Type 3 endoleak is rare but a predominant cause of late rupture. Type 3b endoleak can be misdiagnosed as type 2 endoleak, which is more frequent. Here we report two cases of type 3b endoleak mimicking type 2 endoleak, which were successfully treated by open surgery of partial explantation of the stent-graft and endoaneurysmal interposition graft replacement...
June 2017: Vascular Specialist International
https://www.readbyqxmd.com/read/28680081/bioparr-a-software-system-for-estimating-the-rupture-potential-index-for-abdominal-aortic-aneurysms
#13
Grand Roman Joldes, Karol Miller, Adam Wittek, Rachael O Forsythe, David E Newby, Barry J Doyle
An abdominal aortic aneurysm (AAA) is a permanent and irreversible dilation of the lower region of the aorta. It is a symptomless condition that, if left untreated, can expand until rupture. Despite ongoing efforts, an efficient tool for accurate estimation of AAA rupture risk is still not available. Furthermore, a lack of standardisation across current approaches and specific obstacles within computational workflows limit the translation of existing methods to the clinic. This paper presents BioPARR (Biomechanics based Prediction of Aneurysm Rupture Risk), a software system to facilitate the analysis of AAA using a finite element analysis based approach...
July 5, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28677408/delayed-sigmoid-ischemic-rupture-following-open-repair-abdominal-aortic-aneurysm
#14
Thomas Kotsis, Panagitsa Christoforou, Nikolaos Asaloumidis, Ioannis Papaconstantinou
Colon ischemia following aortic reconstruction is a severe complication with an incidence of 1% to 2% of the operated patients; this infrequent complication will be lethal for nearly half of these patients. Commonly, colon ischemia may be an intraoperative observation or an early postoperative finding. However, in the case presented here, sigmoid rupture and small and large intestine communication was revealed 3 months following repair of the abdominal aorta. A 71-year-old man, following open repair of an abdominal aortic aneurysm, went home on the fifth postoperative day...
January 1, 2017: Vascular and Endovascular Surgery
https://www.readbyqxmd.com/read/28675302/development-of-a-practical-approach-to-expert-elicitation-for-randomised-controlled-trials-with-missing-health-outcomes-application-to-the-improve-trial
#15
Alexina J Mason, Manuel Gomes, Richard Grieve, Pinar Ulug, Janet T Powell, James Carpenter
BACKGROUND/AIMS: The analyses of randomised controlled trials with missing data typically assume that, after conditioning on the observed data, the probability of missing data does not depend on the patient's outcome, and so the data are 'missing at random' . This assumption is usually implausible, for example, because patients in relatively poor health may be more likely to drop out. Methodological guidelines recommend that trials require sensitivity analysis, which is best informed by elicited expert opinion, to assess whether conclusions are robust to alternative assumptions about the missing data...
July 1, 2017: Clinical Trials: Journal of the Society for Clinical Trials
https://www.readbyqxmd.com/read/28674268/oral-steroid-use-and-abdominal-aortic-aneurysm-expansion%C3%A3-positive-association
#16
Yuta Tajima, Hitoshi Goto, Masato Ohara, Munetaka Hashimoto, Daijiro Akamatsu, Takuya Shimizu, Noriyuki Miyama, Ken Tsuchida, Keiichiro Kawamura, Michihisa Umetsu, Shunya Suzuki, Noriaki Ohuchi
BACKGROUND: The maximum axial diameter (MAD) of a fusiform abdominal aortic aneurysm (AAA) is an indicator of the risk of expansion or rupture. Apart from smoking and MAD itself, few expansion risk factors have been reported. In this study, we investigated expansion risk factors for AAA.Methods and Results:This retrospective cohort study included 176 patients who attended Tohoku University Hospital with infrarenal fusiform AAA. AAA expansion rate was determined on multidetector computed tomography, and the correlations between expansion rate and the clinical data were analyzed...
June 30, 2017: Circulation Journal: Official Journal of the Japanese Circulation Society
https://www.readbyqxmd.com/read/28670289/non-coding-rna-contribution-to-thoracic-and-abdominal-aortic-aneurysm-disease-development-and-progression
#17
REVIEW
Yuhuang Li, Lars Maegdefessel
Multiple research groups have started to uncover the complex genetic and epigenetic machinery necessary to maintain cardiovascular homeostasis. In particular, the key contribution of non-coding RNAs (ncRNAs) in regulating gene expression has recently received great attention. Aneurysms in varying locations of the aorta are defined as permanent dilations, predisposing to the fatal consequence of rupture. The characteristic pathology of an aneurysm is characterized by progressive vessel wall dilation, promoted by dying vascular smooth muscle cells and limited proliferation, as well as impaired synthesis and degradation of extracellular matrix components, which at least partially is the result of transmural inflammation and its disruptive effect on vessel wall homeostasis...
2017: Frontiers in Physiology
https://www.readbyqxmd.com/read/28670064/coronary-arterial-aneurysms-in-previously-transplanted-donor-hearts
#18
Nitin Kondapalli, William C Roberts
Described herein is a 57-year-old man who had had a cardiac transplant 5 years earlier (at age 52) and died of a ruptured abdominal aortic aneurysm. The donor heart was found to have a fusiform aneurysm, each filled with thrombus, in 2 major epicardial coronary arteries.
July 2017: Proceedings of the Baylor University Medical Center
https://www.readbyqxmd.com/read/28666818/morphological-and-biomechanical-features-in-abdominal-aortic-aneurysm-with-long-and-short-neck-case-control-study-in-64-abdominal-aortic-aneurysms
#19
I Koncar, D Nikolic, Z Milosevic, N Ilic, M Dragas, M Sladojevic, M Markovic, N Filipovic, L Davidovic
INTRODUCTION: Both, open and endovascular, procedures are related to higher complication rate in abdominal aortic aneurysm (AAA) with shorter neck. Previous study showed that long neck AAA might have lower risk of rupture. Estimation of biomechanical forces in AAA improves rupture risk assessment. Aim of this study was to compare morphological features and biomechanical forces in the short and long neck AAA with threshold of 15mm. METHODS: DICOM images of 64 aneurysms were prospectively collected and analyzed in a case control study...
June 27, 2017: Annals of Vascular Surgery
https://www.readbyqxmd.com/read/28662928/surveillance-after-endovascular-aortic-repair
#20
Feras Zaiem, Jehad Almasri, Mouaffaa Tello, Larry J Prokop, Elliot L Chaikof, Mohammad Hassan Murad
OBJECTIVE: The objective of this systematic review and meta-analysis was to evaluate the optimal modality and frequency of surveillance after endovascular aortic repair (EVAR) in adult patients with abdominal aortic aneurysms. METHODS: We searched for studies of post-EVAR surveillance in MEDLINE In-Process & Other Non-Indexed Citations, MEDLINE, Embase, Cochrane Database of Systematic Reviews, and Scopus through May 10, 2016. The outcomes of interest were endoleaks, mortality, limb ischemia, renal complications, late rupture, and aneurysm-related mortality...
June 26, 2017: Journal of Vascular Surgery
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