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https://www.readbyqxmd.com/read/27926632/a-pooled-analysis-of-robotic-versus-laparoscopic-surgery-for-colon-cancer
#1
Bo-Shi Duan, Guo-Hua Zhao, Helen Yang, Yue Wang
OBJECTIVE: An increasing number of studies have been reported since the "Da Vinci" Robotic System was used in gastrointestinal disease. Thus, we conducted this meta-analysis to evaluate the safety and efficacy of robotic colectomy (RC) compared with laparoscopic colectomy (LC) in the treatment of colon cancer. METHOD: A systematic search of Medline, Embase databases, and the Cochrane Library was performed to identify studies that compared RC and LC and were published up to February 2015...
December 2016: Surgical Laparoscopy, Endoscopy & Percutaneous Techniques
https://www.readbyqxmd.com/read/27926576/laparoscopic-intragastric-resection-an-alternative-technique-for-minimally-invasive-treatment-of-gastric-submucosal-tumors
#2
Cindy Boulanger-Gobeil, Jean-Pierre Gagné, François Julien, Valérie Courval, Kaitlyn Beyfuss, Shady Ashamalla, Julie Hallet
OBJECTIVE: To present the technique for and early results of laparoscopic intragastric resection (LIGR). BACKGROUND: Treatment of confirmed or suspected submucosal gastric malignancies relies on clear margin resection, for which minimally invasive surgery is widely accepted. However, resection in some localization remains challenging. METHODS: We present the steps of LIGR for gastric submucosal tumors (GSMTs). We report the results of LIGR in consecutive patients operated at 2 institutions, including intraoperative, pathologic, 30-day major morbidity and mortality characteristics...
December 6, 2016: Annals of Surgery
https://www.readbyqxmd.com/read/27926566/vaginal-access-minimally-invasive-surgery-for-repair-of-a-postanastomotic-rectovaginal-fistula-a-video-description-of-a-novel-method
#3
Sam Atallah, Arielle Dubose, Sergio Larach
No abstract text is available yet for this article.
January 2017: Diseases of the Colon and Rectum
https://www.readbyqxmd.com/read/27926565/oncologic-outcomes-following-laparoscopic-versus-open-resection-of-pt4-colon-cancer-a-systematic-review-and-meta-analysis
#4
Adina E Feinberg, Tyler R Chesney, Sergio A Acuna, Tarik Sammour, Fayez A Quereshy
BACKGROUND: Locally advanced colon cancer is considered a relative contraindication for laparoscopic resection, and clinical trials addressing the oncologic safety are lacking. OBJECTIVE: The aim of this study was to synthesize the oncologic outcomes associated with laparoscopic versus conventional open surgery for locally advanced colon cancers. DATA SOURCES: We systematically searched Medline, Embase, Central, and ClinicalTrials.gov. STUDY SELECTION: Two reviewers independently screened the literature for controlled trials or observational studies comparing curative-intent laparoscopic and open surgery for colon cancer...
January 2017: Diseases of the Colon and Rectum
https://www.readbyqxmd.com/read/27926554/intraoperative-archive-of-right-colonic-vascular-variability-aids-central-vascular-ligation-and-redefines-gastrocolic-trunk-of-henle-variants
#5
Jamal F Alsabilah, Syed A Razvi, Mahdi H Albandar, Nam K Kim
BACKGROUND: Vascular supply to the right colon has become an issue because of high variability and subsequent impact on minimally invasive surgery. Past cadaveric or radiologic anatomic assessments are noncomprehensive. OBJECTIVE: Intraoperative charting of right colonic arteriovenous anatomy was undertaken to determine the incidence and scope of vascular variations. DESIGN: Vascular anatomy variations were documented in snapshot images, captured during laparoscopic video recordings or through open surgical digital photography...
January 2017: Diseases of the Colon and Rectum
https://www.readbyqxmd.com/read/27926517/suberoylanilide-hydroxamic-acid-induced-specific-epigenetic-regulation-controls-leptin-induced-proliferation-of-breast-cancer-cell-lines
#6
Xiuyan Feng, Han Han, Dan Zou, Jiaming Zhou, Weiqiang Zhou
Breast cancer is one of the most common malignancies among women in the world, investigating the characteristics and special transduction pathways is important for better understanding breast development and tumorigenesis. Leptin, a peptide hormone secreted from white adipocytes, may be an independent risk factor for breast cancer.Here, we treated suberoylanilide hydroxamic acid (SAHA) on Leptin-induced cell proliferation and invasion in the estrogen-receptor-positive breast cancer cell line MCF-7 and triple-negative breast cancer cell line MDA-MB-231...
December 1, 2016: Oncotarget
https://www.readbyqxmd.com/read/27925585/using-contact-forces-and-robot-arm-accelerations-to-automatically-rate-surgeon-skill-at-peg-transfer
#7
Jeremy Brown, Conor O'Brien, Sarah Leung, Kristoffel Dumon, David Lee, Katherine Kuchenbecker
OBJECTIVE: Most trainees begin learning robotic minimally invasive surgery by performing inanimate practice tasks with clinical robots such as the Intuitive Surgical da Vinci. Expert surgeons are commonly asked to evaluate these performances using standardized five-point rating scales, but doing such ratings is time consuming, tedious, and somewhat subjective. This article presents an automatic skill evaluation system that analyzes only the contact force with the task materials, the broad-bandwidth accelerations of the robotic instruments and camera, and the task completion time...
December 2, 2016: IEEE Transactions on Bio-medical Engineering
https://www.readbyqxmd.com/read/27925393/intensive-care-unit-icu-readmission-after-major-lung-resection-prevalence-patterns-and-mortality
#8
Jae Jun Jung, Jong Ho Cho, Tae Hee Hong, Hong Kwan Kim, Yong Soo Choi, Jhingook Kim, Young Mog Shim, Jae Ill Zo
BACKGROUND: The aim of this study was to identify risk factors associated with mortality in patients re-admitted to an intensive care unit (ICU) after initial recovery from major lung resection. METHODS: We retrospectively reviewed the case records of all patients who underwent major lung resection between February 2011 and May 2013. A total of 1916 patients underwent major resection surgery for various lung diseases, 63 (3.3%) of which required ICU admission after initial recovery...
December 7, 2016: Thoracic Cancer
https://www.readbyqxmd.com/read/27925305/extracellular-matrix-in-epitheliochorial-endotheliochorial-and-haemochorial-placentation-and-its-potential-application-for-regenerative-medicine
#9
REVIEW
Ara da Anunciação, A M Mess, D Orechio, B A Aguiar, P O Favaron, M A Miglino
A placenta is defined as structural approximation of maternal and foetal tissues to perform physiological exchange. Associated processes of differentiation and the establishment of its cells take place within the extracellular matrix (ECM) that provides a rich environment of collagens, fibronectins, cytokines and other components. Placental ECM is promising for tissue regeneration purposes, because it has immune tolerance capacities that may cause only minimal rejections of transplants with immunological differences between donor and recipient...
December 7, 2016: Reproduction in Domestic Animals, Zuchthygiene
https://www.readbyqxmd.com/read/27925235/quantification-of-operational-learning-in-minimal-invasive-extracorporeal-circulation
#10
Kyriakos Anastasiadis, Polychronis Antonitsis, Christos Asteriou, Helena Argiriadou, Apostolos Deliopoulos, Dimitrios Konstantinou, Vassilios Grosomanidis, Paschalis Tossios
Minimal invasive extracorporeal circulation (MiECC) has initiated important new efforts within science and technology towards a more physiologic perfusion. In this study, we aim to investigate the learning curve of our center regarding MiECC. We studied a series of 150 consecutive patients who underwent elective coronary artery bypass grafting by the same surgical team during the initial phase of MiECC application. Patients were randomly assigned into two groups. Group A (n = 75) included patients operated on MiECC, while group B (n = 75) included patients operated with conventional cardiopulmonary bypass (cCPB)...
December 7, 2016: Artificial Organs
https://www.readbyqxmd.com/read/27925173/potential-of-long-non-coding-rnas-in-cancer-patients-from-bio-markers-to-therapeutic-targets
#11
REVIEW
Subash Chandra Gupta, Yashoda Nandan Tripathi
Because of high specificity and easy detection in the tissues, serum, plasma, urine and saliva, interest in exploring the potential of long non-coding RNAs (lncRNAs) in cancer patients continues to increase. LncRNAs have shown potential as a bio-marker in the diagnosis and prognosis of bladder cancer, prostate cancer, gastric cancer, pancreatic cancer, breast cancer, and many other cancer types. Some lncRNAs have also been used as adjunct to improve the specificity and sensitivity of existing biomarkers. The molecular tools such as RNA-seq, RNA-FISH, ic-SHAPE and quantitative real-time PCR have been used for examining the lncRNAs' potential...
December 7, 2016: International Journal of Cancer. Journal International du Cancer
https://www.readbyqxmd.com/read/27924506/gasless-laparoscopic-surgery-plus-abdominal-wall-lifting-for-giant-hiatal-hernia-our-single-center-experience
#12
Jiang-Hong Yu, Ji-Xiang Wu, Lei Yu, Jian-Ye Li
Giant hiatal hernia (GHH) comprises 5% of hiatal hernia and is associated with significant complications. The traditional operative procedure, no matter transthoracic or transabdomen repair of giant hiatal hernia, is characteristic of more invasion and more complications. Although laparoscopic repair as a minimally invasive surgery is accepted, a part of patients can not tolerate pneumoperitoneum because of combination with cardiopulmonary diseases or severe posterior mediastinal and neck emphesema during operation...
December 2016: Journal of Huazhong University of Science and Technology. Medical Sciences
https://www.readbyqxmd.com/read/27924469/a-methylcellulose-and-collagen-based-temperature-responsive-hydrogel-promotes-encapsulated-stem-cell-viability-and-proliferation-in-vitro
#13
Christina Payne, Eimear B Dolan, Janice O'Sullivan, Sally-Ann Cryan, Helena M Kelly
With the number of stem cell-based therapies emerging on the increase, the need for novel and efficient delivery technologies to enable therapies to remain in damaged tissue and exert their therapeutic benefit for extended periods, has become a key requirement for their translation. Hydrogels, and in particular, thermoresponsive hydrogels, have the potential to act as such delivery systems. Thermoresponsive hydrogels, which are polymer solutions that transform into a gel upon a temperature increase, have a number of applications in the biomedical field due to their tendency to maintain a liquid state at room temperature, thereby enabling minimally invasive administration and a subsequent ability to form a robust gel upon heating to physiological temperature...
December 6, 2016: Drug Delivery and Translational Research
https://www.readbyqxmd.com/read/27924395/the-effect-of-postoperative-complications-on-survival-of-patients-after-minimally-invasive-esophagectomy-for-esophageal-cancer
#14
Kun-Kun Li, Yin-Jian Wang, Xue-Hai Liu, Qun-You Tan, Yao-Guang Jiang, Wei Guo
BACKGROUND: Minimally invasive esophagectomy (MIE) has been shown to be a feasible technique for the treatment of esophageal cancer; however, its postoperative morbidity remains high. This retrospective study aimed to evaluate the effect of postoperative complications on long-term outcomes in patients who have undergone MIE for esophageal squamous cell carcinoma (ESCC). METHODS: This retrospective study enrolled patients who had undergone MIE for ESCC between September 2009 and November 2014; all procedures were performed by a single surgical team...
December 6, 2016: Surgical Endoscopy
https://www.readbyqxmd.com/read/27924388/laparoscopic-and-robotic-skills-are-transferable-in-a-simulation-setting-a-randomized-controlled-trial
#15
Lauren Thomaier, Megan Orlando, Melinda Abernethy, Chandhana Paka, Chi Chiung Grace Chen
BACKGROUND: Although surgical simulation provides an effective supplement to traditional training, it is not known whether skills are transferable between minimally invasive surgical modalities. The purpose of this study was to assess the transferability of skills between minimally invasive surgical simulation platforms among simulation-naïve participants. METHODS: Forty simulation-naïve medical students were enrolled in this randomized single-blinded controlled trial...
December 6, 2016: Surgical Endoscopy
https://www.readbyqxmd.com/read/27924208/local-anesthesia-with-monitored-anesthesia-care-for-patients-undergoing-thyroidectomy-a-case-series
#16
Se Eun Kim, Eugene Kim
Because the current trend favors minimally invasive surgery for thyroid disease, increasing interest has developed for thyroidectomy under local anesthesia with monitored anesthesia care (MAC). Here, we retrospectively reviewed 18 cases of thyroidectomy performed under local anesthesia with MAC in a single center. All of the procedures were performed by a single surgeon, using local lidocaine infiltration around the incisional site and propofol plus remifentanil target-controlled infusion. Sore throat (4/18), hypocalcemia (1/18), and transient voice color change (1/18) were observed, but the patients recovered during the follow-up period...
December 2016: Korean Journal of Anesthesiology
https://www.readbyqxmd.com/read/27923763/minimally-invasive-hardware-removal-after-minimally-invasive-distal-radius-plate-osteosynthesis-mipo-feasibility-study-in-a-388-case-series
#17
Pier Luigi Medda, Anne-Sophie Matheron, Juan José Hidalgo Diaz, Nicolas Maire, Paul Vernet, Sybille Facca, Philippe Liverneaux
The aim of the present study was to assess the technical feasibility of minimally invasive volar plate removal following distal radius fracture. 388 plates removed from 387 patients (357 female: mean age, 50 years) were assessed retrospectively. The incision used the primary minimally invasive approach and was closed after plate removal by intradermal continuous suture, without drainage or immobilization. Mean scar size was 22.2mm preoperatively, and the incision was 19.8mm at start and 21.4mm at end of procedure, these differences being non-significant...
December 3, 2016: Orthopaedics & Traumatology, Surgery & Research: OTSR
https://www.readbyqxmd.com/read/27923571/a-simple-dried-blood-spot-method-for-in-vivo-measurement-of-ureagenesis-by-gas-chromatography-mass-spectrometry-using-stable-isotopes
#18
Gabriella Allegri, Sereina Deplazes, Hiu Man Viecelli, Déborah Mathis, Ralph Fingerhut, Johannes Häberle, Beat Thöny
BACKGROUND: Clinical management of inherited or acquired hyperammonemia depends mainly on the plasma ammonia level which is not a reliable indicator of urea cycle function as its concentrations largely fluctuate. The gold standard to assess ureagenesis in vivo is the use of stable isotopes. METHODS: Here we developed and validated a simplified in vivo method with [(15)N]ammonium chloride ([(15)N]H4Cl) as a tracer. Non-labeled and [(15)N]urea were quantified by GC-MS after extraction and silylation...
December 3, 2016: Clinica Chimica Acta; International Journal of Clinical Chemistry
https://www.readbyqxmd.com/read/27923451/microrna-guided-diagnostics-in-clinical-samples
#19
REVIEW
Dakota Gustafson, Kathrin Tyryshkin, Neil Renwick
miRNA-guided diagnostics is a powerful molecular approach for evaluating clinical samples through miRNA detection and/or visualization. To date, this approach has been successfully used to diagnose, manage, and/or monitor a wide range of neoplastic and non-neoplastic diseases. Despite the promise of miRNA-guided diagnostics, particularly in the field of minimally invasive biomarkers, several knowledge and practical issues confound or hinder translation into routine clinical practice including: miRNA sequence database errors, suboptimal RNA extraction methods, detection assay variability, a vast array of online resources for bioinformatic analyses, and non-standardized statistical analyses for miRNA clinical testing...
October 2016: Best Practice & Research. Clinical Endocrinology & Metabolism
https://www.readbyqxmd.com/read/27922988/minimally-invasive-fundoplication-is-safe-and-effective-in-patients-with-severe-esophageal-hypomotility
#20
Michael B Goldberg, Abbas El-Sayed Abbas, Michael S Smith, Henry P Parkman, Ron Schey, Daniel T Dempsey
OBJECTIVE: Fundoplication is used to treat refractory gastroesophageal reflux disease (GERD). A subset of patients has coexisting esophageal dysmotility, including aperistalsis or hypoperistalsis. These patients may be at increased risk of dysphagia after fundoplication. To evaluate the outcomes of minimally invasive fundoplication (MIF) in patients with GERD and esophageal hypomotility. METHODS: Retrospective review of all patients who underwent MIF and had severe esophageal hypomotility from January 2003 to June 2013...
December 5, 2016: Innovations: Technology and Techniques in Cardiothoracic and Vascular Surgery
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