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D T P Trafalis, E Chrysogelou, P Dalezis, G Geromichalos, M Kontos, C Andreadis, N Ziras, M Koutsilieris, A E Athanassiou, G A Pangalis, A Papageorgiou
PURPOSE: A wide variety of human malignancies, including lymphoproliferative neoplasms, express somatistatin (SS) receptors (SS-R). SS induces apoptosis and exerts pronounced antiproliferative effects on various human tumors cell lines, human xenografts, and animal tumors including P388 lymphocytic leukemia. In patients with thymoma the combination of octreotide (OCT) with corticosteroids improves the overall response rate. It has been reported that SS can increase glucocorticoid activity...
January 2005: Journal of B.U.ON.: Official Journal of the Balkan Union of Oncology
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