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https://www.readbyqxmd.com/read/29339266/long-term-trend-analysis-on-total-and-extreme-precipitation-over-shasta-dam-watershed
#1
Kinya Toride, Dylan L Cawthorne, Kei Ishida, M Levent Kavvas, Michael L Anderson
California's interconnected water system is one of the most advanced water management systems in the world, and understanding of long-term trends in atmospheric and hydrologic behavior has increasingly being seen as vital to its future well-being. Knowledge of such trends is hampered by the lack of long-period observation data and the uncertainty surrounding future projections of atmospheric models. This study examines historical precipitation trends over the Shasta Dam watershed (SDW), which lies upstream of one of the most important components of California's water system, Shasta Dam, using a dynamical downscaling methodology that can produce atmospheric data at fine time-space scales...
January 13, 2018: Science of the Total Environment
https://www.readbyqxmd.com/read/29334956/identification-and-characterization-of-areas-of-high-and-low-risk-for-asymptomatic-malaria-infections-at-sub-village-level-in-ratanakiri-cambodia
#2
Lies Durnez, Myrthe Pareyn, Vanna Mean, Saorin Kim, Nimol Khim, Didier Menard, Marc Coosemans, Tho Sochantha, Vincent Sluydts
BACKGROUND: Malaria elimination needs a concentration of activities towards identification of residual transmission foci and intensification of efforts to eliminate the last few infections, located in so-called 'malaria hotspots'. Previous work on characterizing malaria transmission hotspots has mainly focused on falciparum malaria and especially on symptomatic cases, while the malaria reservoir is expected to be mainly concentrated in the asymptomatic human population when transmission is low...
January 15, 2018: Malaria Journal
https://www.readbyqxmd.com/read/29332453/mri-related-geometric-distortions-in-stereotactic-radiotherapy-treatment-planning-evaluation-and-dosimetric-impact
#3
Eleftherios P Pappas, Mukhtar Alshanqity, Argyris Moutsatsos, Hani Lababidi, Khalid Alsafi, Konstantinos Georgiou, Pantelis Karaiskos, Evangelos Georgiou
In view of their superior soft tissue contrast compared to computed tomography, magnetic resonance images are commonly involved in stereotactic radiosurgery/radiotherapy applications for target delineation purposes. It is known, however, that magnetic resonance images are geometrically distorted, thus deteriorating dose delivery accuracy. The present work focuses on the assessment of geometric distortion inherent in magnetic resonance images used in stereotactic radiosurgery/radiotherapy treatment planning and attempts to quantitively evaluate the consequent impact on dose delivery...
December 2017: Technology in Cancer Research & Treatment
https://www.readbyqxmd.com/read/29314358/detection-of-indistinct-fe-n-stretching-bands-in-iron-v-nitrides-by-photodissociation-spectroscopy
#4
Erik Andris, Rafael Navrátil, Juraj Jašík, Gerard Sabenya, Miquel Costas, Martin Srnec, Jana Roithová
We report for the first time infrared spectra of three non-heme pseudo-octahedral iron(V) nitride complexes with assigned Fe-N stretching vibrations. The intensities of the Fe-N bands in two of the complexes are extremely weak. Their detection was enabled by the high resolution and sensitivity of the experiments performed at 3 K for isolated complexes in the gas phase. Multireference CASPT2 calculations revealed that the Fe-N bond in the ground doublet state is influenced by two low-lying excited doublet states...
January 3, 2018: Chemistry: a European Journal
https://www.readbyqxmd.com/read/29312834/joint-damage-is-amplified-in-rheumatoid-arthritis-patients-with-positive-thyroid-autoantibodies
#5
Yu-Lan Chen, Jian-Zi Lin, Ying-Qian Mo, Jin-Jian Liang, Qian-Hua Li, Cheng-Jing Zhou, Xiu-Ning Wei, Jian-Da Ma, Ze-Hong Yang, Dong-Hui Zheng, Lie Dai
Background: Autoimmune thyroid disease (AITD), which is characterized by an increased presence of thyroid autoantibodies (TAbs), such as antibodies against thyroid peroxidase (TPOAbs) and antibodies against thyroglobulin (TgAbs), has been reported to be associated with rheumatoid arthritis (RA) because AITD and RA both involve autoimmunity. However, few data are available on the incidence of TAbs in Chinese RA patients, and studies on the association between TAbs and joint damage as well as synovitis in RA patients remain sparse...
2018: PeerJ
https://www.readbyqxmd.com/read/29310570/thresher-determining-the-number-of-clusters-while-removing-outliers
#6
Min Wang, Zachary B Abrams, Steven M Kornblau, Kevin R Coombes
BACKGROUND: Cluster analysis is the most common unsupervised method for finding hidden groups in data. Clustering presents two main challenges: (1) finding the optimal number of clusters, and (2) removing "outliers" among the objects being clustered. Few clustering algorithms currently deal directly with the outlier problem. Furthermore, existing methods for identifying the number of clusters still have some drawbacks. Thus, there is a need for a better algorithm to tackle both challenges...
January 8, 2018: BMC Bioinformatics
https://www.readbyqxmd.com/read/29305871/resting-heart-rate-a-physiological-predicator-of-lie-detection-ability
#7
Geoffrey Duran, Isabelle Tapiero, George A Michael
This study explored a psychophysiological measure, Resting Heart Rate (RHR), as a predicator of the ability to detect lies. RHR was recorded for 1min and followed by a deception detection task in which participants were required to judge 24 videos of people describing a real-life event (50% truthful, 50% deceptive). Multiple regression analyses showed that, among other individual characteristics, only RHR predicted the ability to distinguish truth from lies. Importantly, the prediction was negative. This result suggests that the higher the RHR, the worse the detection of lies...
January 3, 2018: Physiology & Behavior
https://www.readbyqxmd.com/read/29304275/intrinsic-disorder-in-a-well-folded-globular-protein
#8
Nahren Manuel Mascarenhas, Vishram L Terse, Shachi Gosavi
The folded structure of the heterodimeric sweet protein monellin mimics single-chain proteins of the topology β1-α1-β2-β3-β4-β5 (chain A: β3-β4-β5 and chain B: β1-α1-β2). Further, like naturally occurring single-chain proteins of a similar size, monellin folds cooperatively with no detectable intermediates. However, the two monellin chains, A and B, are marginally structured in isolation and fold only upon binding to each other. Thus, monellin presents a unique opportunity to understand the design of intrinsically disordered proteins that fold upon binding...
January 5, 2018: Journal of Physical Chemistry. B
https://www.readbyqxmd.com/read/29302480/comparison-of-indocyanine-green-fluorescence-and-parathyroid-autofluorescence-imaging-in-the-identification-of-parathyroid-glands-during-thyroidectomy
#9
Bora Kahramangil, Eren Berber
Background: Indocyanine green fluorescence (ICGF) and parathyroid autofluorescence (AF) are two new techniques that aid in the identification of parathyroid glands (PG) intraoperatively during thyroidectomy. There is no study comparing the efficacy of these techniques. Methods: This was an IRB-approved clinical study comparing the utility of ICGF and AF for identification of PGs during thyroidectomy. Data were collected prospectively. Both techniques were compared to naked eye (NE) for PG detection...
December 2017: Gland Surgery
https://www.readbyqxmd.com/read/29298934/evolutionary-and-structural-analyses-uncover-a-role-for-solvent-interactions-in-the-diversification-of-cocoonases-in-butterflies
#10
G Smith, J E Kelly, A Macias-Muñoz, C T Butts, R W Martin, A D Briscoe
Multi-omic approaches promise to supply the power to detect genes underlying disease and fitness-related phenotypes. Optimal use of the resulting profusion of data requires detailed investigation of individual candidate genes, a challenging proposition. Here, we combine transcriptomic and genomic data with molecular modelling of candidate enzymes to characterize the evolutionary history and function of the serine protease cocoonase. Heliconius butterflies possess the unique ability to feed on pollen; recent work has identified cocoonase as a candidate gene in pollen digestion...
January 10, 2018: Proceedings. Biological Sciences
https://www.readbyqxmd.com/read/29290435/moderate-lameness-leads-to-marked-behavioral-changes-in-dairy-cows
#11
H C Weigele, L Gygax, A Steiner, B Wechsler, J-B Burla
Lameness is one of the most prevalent diseases affecting the welfare of cows in modern dairy production. Lameness leads to behavioral changes in severely lame cows, which have been investigated in much detail. For early detection of lameness, knowledge of the effects of moderate lameness on cow behavior is crucial. Therefore, the behavior of nonlame and moderately lame cows was compared on 17 Swiss dairy farms. On each farm, 5 to 11 nonlame (locomotion score 1 of 5) and 2 to 7 moderately lame (locomotion score 3 of 5) cows were selected for data collection in two 48-h periods (A, B) separated by an interval of 6 to 10 wk...
December 28, 2017: Journal of Dairy Science
https://www.readbyqxmd.com/read/29289814/safety-and-acceptability-of-human-papillomavirus-testing-of-self-collected-specimens-a-methodologic-study-of-the-impact-of-collection-devices-and-hpv-assays-on-sensitivity-for-cervical-cancer-and-high-grade-lesions
#12
Maarit K Leinonen, Kristina Schee, Christine M Jonassen, A Kathrine Lie, Camilla F Nystrand, Anbjørg Rangberg, Ingegerd E Furre, Marzena J Johansson, Ameli Tropé, Katrine D Sjøborg, Philip E Castle, Mari Nygård
BACKGROUND: Comparative data on different self-collection methods is limited. OBJECTIVES: To assess the impact of hrHPV testing of two self-collection devices for detection of cervical carcinoma and high-grade lesions. STUDY DESIGN: Three hundred ten patients collected two cervicovaginal specimens using a brush (Evalyn®Brush) and a swab (FLOQSwabs™), and filled a questionnaire at home. Then, a physician at the clinic took a cervical specimen into PreservCyt® buffer for hrHPV testing and cytology...
December 21, 2017: Journal of Clinical Virology: the Official Publication of the Pan American Society for Clinical Virology
https://www.readbyqxmd.com/read/29289135/probing-resonant-energy-transfer-in-collisions-of-ammonia-with-rydberg-helium-atoms-by-microwave-spectroscopy
#13
V Zhelyazkova, S D Hogan
We present the results of experiments demonstrating the spectroscopic detection of Förster resonance energy transfer from NH3 in the X1A1 ground electronic state to helium atoms in 1sns 3S1 Rydberg levels, where n = 37 and n = 40. For these values of n, the 1sns 3S1 → 1snp 3PJ transitions in helium lie close to resonance with the ground-state inversion transitions in NH3 and can be tuned through resonance using electric fields of less than 10 V/cm. In the experiments, energy transfer was detected by direct state-selective electric field ionization of the 3S1 and 3PJ Rydberg levels and by monitoring the population of the 3DJ levels following pulsed microwave transfer from the 3PJ levels...
December 28, 2017: Journal of Chemical Physics
https://www.readbyqxmd.com/read/29287920/microbiological-diagnosis-of-infections-caused-by-the-genus-mycobacterium
#14
Sofía Samper, Julià González-Martin
Mycobacterial culture has a high sensitivity and is the test of choice for the microbiological diagnosis of tuberculosis and nontuberculous mycobacterial infections. However, the results of this culture require at least 2-3 weeks to obtain positivity. Staining is rapid and can be used as a complementary study, although its sensitivity is low. Gene amplification tests have an intermediate sensitivity and obtain results in 1-2 days. These last tests are indicated in cases with moderate or high clinical suspicion...
December 26, 2017: Enfermedades Infecciosas y Microbiología Clínica
https://www.readbyqxmd.com/read/29287854/systematic-review-of-knowledge-of-attitudes-towards-and-practices-for-newborn-hearing-screening-among-healthcare-professionals
#15
REVIEW
Rohit Ravi, Dhanshree R Gunjawate, Krishna Yerraguntla, Bellur Rajashekhar
INTRODUCTION: The success of newborn hearing screening programs lies in the timely identification, diagnosis, and management of children with hearing loss accomplished via a multidisciplinary newborn hearing screening (NHS) team. The team is typically comprised of various healthcare professionals who act as decision makers as well as facilitators for different stages in the screening process. Team members' knowledge of, attitudes towards, and practices for early hearing detection and intervention programs are critical for success and prevention of loss to follow up...
January 2018: International Journal of Pediatric Otorhinolaryngology
https://www.readbyqxmd.com/read/29287151/effects-of-stacked-wedge-pads-and-chains-applied-to-the-forefeet-of-tennessee-walking-horses-for-a-five-day-period-on-behavioral-and-biochemical-indicators-of-pain-stress-and-inflammation
#16
James B Everett, Jim Schumacher, Thomas J Doherty, Randi A Black, Lisa L Amelse, Peter Krawzel, Johann F Coetzee, Brian K Whitlock
OBJECTIVE To determine the effects of stacked wedge pads and chains applied to the forefeet of Tennessee Walking Horses on behavioral and biochemical indicators of pain, stress, and inflamation. ANIMALS 20 Tennessee Walking Horses. PROCEDURES Horses were randomly assigned to 2 treatment groups: keg shoes (control; n = 10) or stacked wedge pads and exercise with chains (10). Ten days before treatment application, an accelerometer was attached at the left metatarsus of each horse to record daily activity. Horses were exercised for 20 minutes daily, beginning on day -7...
January 2018: American Journal of Veterinary Research
https://www.readbyqxmd.com/read/29283889/two-dimensional-cspbbr3-pcbm-heterojunctions-for-sensitive-fast-and-flexible-photodetectors-boosted-by-charge-transfer
#17
Yalong Shen, Dejian Yu, Xiong Wang, Chengxue Huo, Ye Wu, Zhengfeng Zhu, Haibo Zeng
Inorganic halide perovskites (IHPs) exhibited promising potentials for high-performance wide-band photodetectors (PDs) due to their high light absorption coefficients, long carrier diffusion length and wide light absorption ranges. Here, we report two-dimensional (2D) CsPbBr3/PCBM heterojunctions for sensitive, fast and flexible photodetectors, whose performances can be greatly boosted by the charge transfer through the energy-aligned interface. The 2D CsPbBr3 nanosheets (NSs) with high crystallinity were fabricated via a simple solution-process at room temperature, and then assembled into flexible heterojunctions films with polymerphenyl-C61-butyric acid methyl ester (PCBM)...
December 28, 2017: Nanotechnology
https://www.readbyqxmd.com/read/29276188/treating-the-secret-disease-sex-sin-and-authority-in-eighteenth-century-venereal-cases
#18
Olivia Weisser
This article looks at cases of venereal disease from the early 1700s and how healers presented themselves as shrewd interpreters of patients' bodies and souls. Because the disease was so stigmatizing, patients were said to be unreliable narrators of their own symptoms and health histories. Practitioners, in turn, exhibited diagnostic expertise by sagely navigating such constraints. They characterized themselves as medical detectives who gathered clues and made diagnoses in spite of patients' alleged lies and omissions...
2017: Bulletin of the History of Medicine
https://www.readbyqxmd.com/read/29274182/screening-for-problem-gambling-within-mental-health-services-a-comparison-of-the-classification-accuracy-of-brief-instruments
#19
N A Dowling, S S Merkouris, V Manning, R Volberg, S J Lee, S N Rodda, D I Lubman
BACKGROUND AND AIMS: Despite the over-representation of people with gambling problems in mental health populations, there is limited information available to guide the selection of brief screening instruments within mental health services. The primary aim was therefore to compare the classification accuracy of nine brief problem gambling screening instruments (2-5 items) with a reference standard among patients accessing mental health services. DESIGN: The classification accuracy of nine brief screening instruments was compared with multiple cut-off scores on a reference standard...
December 23, 2017: Addiction
https://www.readbyqxmd.com/read/29262441/imaging-in-neurocritical-care-practice
#20
Craig Williamson, Larry Morgan, Joshua P Klein
The use of neuroimaging in conjunction with serial neurological examinations is a core component of modern neurocritical care practice. Although there is a growing role for other neuromonitoring techniques, the ability to quickly and accurately interpret images in the context of a patient's clinical status arguably remains the indispensable skill for neurocritical care practitioners. Due to its rapid acquisition time and excellent ability to detect intracerebral hemorrhage (ICH), cerebral edema, and signs of elevated intracranial pressure, computed tomography (CT) remains the most useful neuroimaging technique for intensive care unit (ICU) patients...
December 2017: Seminars in Respiratory and Critical Care Medicine
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