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https://www.readbyqxmd.com/read/29782141/in-situ-assembly-of-well-dispersed-ag-nanoparticles-throughout-electrospun-alginate-nanofibers-for-monitoring-human-breath-smart-fabrics
#1
Jun Zhang, Xiao-Xiong Wang, Bin Zhang, Seeram Ramakrishna, Miao Yu, Jian-Wei Ma, Yun-Ze Long
Alginate nanofibers assembled with sliver nanoparticles throughout the whole nanofiber were fabricated by three steps including electrospinning of Na-alginate nanofibers, ion exchange between the sodium and silver ions, and in situ reduction of silver nanoparticles. The content, distribution and size of the nanoparticles are controllable by tuning reaction conditions. Ag/alginate nanofibers exhibit good humidity sensitivity in a wide humidity range from ambient RH (20%) to 85% RH. Interestingly, these humidity sensors can be attached to a 3M-9001V mask for monitoring human breath during exercise and emotion changes, and this smart exhibits accurate and continuous human-breath tracking no matter how fast or slow as well as how deep or shallow...
May 21, 2018: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/29775771/a-detailed-analysis-of-the-arden-syntax-expression-grammar
#2
Stefan Kraus, Marc Rosenbauer, Lutz Schröder, Thomas Bürkle, Klaus-Peter Adlassnig, Dennis Toddenroth
OBJECTIVE: The Arden Syntax for Medical Logic Systems is a standard for encoding and sharing medical knowledge in the form of Medical Logic Modules. To improve accessibility for clinicians, the originators of the standard deliberately designed Arden Syntax expressions to resemble natural language, and parentheses around operands are not generally required. For certain patterns of nested expressions, however, the use of parentheses is mandatory, otherwise they are not accepted by an Arden Syntax environment...
May 15, 2018: Journal of Biomedical Informatics
https://www.readbyqxmd.com/read/29770441/evaluation-of-the-anti-inflammatory-activity-of-tinospora-cordifolia-willd-miers-chloroform-extract-a-preclinical-study
#3
Sheena Philip, Greeshma Tom, Asha V Vasumathi
OBJECTIVES: Tinospora cordifolia (Willd.) Miers is an inevitable ingredient of Ayurvedic rasayanas for the treatment of disorders with unregulated inflammation. However, studies regarding the mechanism of anti-inflammatory potential of this plant at the molecular level are lacking. METHODS: In vitro evaluations were conducted in RAW264.7 macrophages which were preincubated with chloroform extract of T. cordifolia (CETC) and subsequently stimulated with LPS. The expressions of COX-2, TNF-α and iNOS genes were analysed by SQRT-PCR and Western blot, cytokines (IL-6, IL-1β and PGE2 ) levels by ELISA, NF-κB activation and p38 MAPK phosphorylation by Immunoblot and confocal imaging...
May 16, 2018: Journal of Pharmacy and Pharmacology
https://www.readbyqxmd.com/read/29763583/m%C3%A3-ller-glial-cells-contribute-to-dim-light-vision-in-the-spectacled-caiman-caiman-crocodilus-fuscus-analysis-of-retinal-light-transmission
#4
Silke Agte, Alexey Savvinov, Anett Karl, Astrid Zayas-Santiago, Elke Ulbricht, Vladimir I Makarov, Andreas Reichenbach, Andreas Bringmann, Serguei N Skatchkov
In this study, we show the capability of Müller glial cells to transport light through the inverted retina of reptiles, specifically the retina of the spectacled caimans. Thus, confirming that Müller cells of lower vertebrates also improve retinal light transmission. Confocal imaging of freshly isolated retinal wholemounts, that preserved the refractive index landscape of the tissue, indicated that the retina of the spectacled caiman is adapted for vision under dim light conditions. For light transmission experiments, we used a setup with two axially aligned objectives imaging the retina from both sides to project the light onto the inner (vitreal) surface and to detect the transmitted light behind the retina at the receptor layer...
May 12, 2018: Experimental Eye Research
https://www.readbyqxmd.com/read/29754769/a-statistical-framework-for-mapping-risk-genes-from-de-novo-mutations-in-whole-genome-sequencing-studies
#5
Yuwen Liu, Yanyu Liang, A Ercument Cicek, Zhongshan Li, Jinchen Li, Rebecca A Muhle, Martina Krenzer, Yue Mei, Yan Wang, Nicholas Knoblauch, Jean Morrison, Siming Zhao, Yi Jiang, Evan Geller, Iuliana Ionita-Laza, Jinyu Wu, Kun Xia, James P Noonan, Zhong Sheng Sun, Xin He
Analysis of de novo mutations (DNMs) from sequencing data of nuclear families has identified risk genes for many complex diseases, including multiple neurodevelopmental and psychiatric disorders. Most of these efforts have focused on mutations in protein-coding sequences. Evidence from genome-wide association studies (GWASs) strongly suggests that variants important to human diseases often lie in non-coding regions. Extending DNM-based approaches to non-coding sequences is challenging, however, because the functional significance of non-coding mutations is difficult to predict...
April 30, 2018: American Journal of Human Genetics
https://www.readbyqxmd.com/read/29754299/high-throughput-nir-spectroscopic-nirs-detection-of-microplastics-in-soil
#6
Andrea Paul, Lukas Wander, Roland Becker, Caroline Goedecke, Ulrike Braun
The increasing pollution of terrestrial and aquatic ecosystems with plastic debris leads to the accumulation of microscopic plastic particles of still unknown amount. To monitor the degree of contamination, analytical methods are urgently needed, which help to quantify microplastics (MP). Currently, time-costly purified materials enriched on filters are investigated both by micro-infrared spectroscopy and/or micro-Raman. Although yielding precise results, these techniques are time consuming, and are restricted to the analysis of a small part of the sample in the order of few micrograms...
May 12, 2018: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/29752937/lncrna-thor-promotes-human-renal-cell-carcinoma-cell-growth
#7
Xue-Ting Ye, Hang Huang, Wei-Ping Huang, Wei-Lie Hu
BACKGROUND: Recent studies have characterized a novel but extremely conserved long non-coding RNA (LncRNA) THOR. THOR directly associates with insulin-like growth factor 2 mRNA-binding protein 1 (IGF2BP1) to promote mRNA stabilization of key pro-cancerous genes. RESULTS: Here, we show that THOR is expressed in human renal cell carcinoma (RCC) tissues and established/primary human RCC cells. It was not detected in normal renal tissues nor in HK-2 and primary human renal epithelial cells...
May 9, 2018: Biochemical and Biophysical Research Communications
https://www.readbyqxmd.com/read/29751984/age-related-trajectories-of-social-cognition-in-youth-at-clinical-high-risk-for-psychosis-an-exploratory-study
#8
Charlie A Davidson, Danijela Piskulic, Jean Addington, Kristen S Cadenhead, Tyrone D Cannon, Barbara A Cornblatt, Thomas H McGlashan, Diana O Perkins, Larry J Seidman, Ming T Tsuang, Elaine F Walker, Carrie E Bearden, Daniel H Mathalon, Scott W Woods, Jason K Johannesen
BACKGROUND: Clinical high risk (CHR) status is characterized by impairments in social cognition, but questions remain concerning their stability over development. In cross-sectional analysis of a large naturalistic sample, the current study examined whether those at CHR status show deviant trajectories for age-related change in social cognitive ability, and whether these trajectories are influenced by treatment history. METHOD: Emotion perception (EP) and theory of mind (ToM) were assessed in 675 CHR and 263 healthy comparison (HC) participants aged 12-35...
May 8, 2018: Schizophrenia Research
https://www.readbyqxmd.com/read/29747492/the-change-of-sleeping-and-lying-posture-of-japanese-black-cows-after-moving-into-new-environment
#9
Michiru Fukasawa, Tokushi Komatsu, Yumi Higashiyama
Objective: The environmental change is one of the stressful events in livestock production. Change in environment disturbed cow behavior and cows needed several days to reach stable behavioral pattern, especially sleeping posture (SP) and lying posture (LP) have been used as an indicator for relax and well-acclimated to its environment. The aim of this study examines how long does Japanese black cow required for stabilization of SP and LP after moving into new environment. Methods: Seven pregnant Japanese black cows were used...
April 25, 2018: Asian-Australasian Journal of Animal Sciences
https://www.readbyqxmd.com/read/29747464/discriminating-between-different-heavy-metal-ions-with-fullerene-derived-nanoparticles
#10
Erica Ciotta, Paolo Prosposito, Pietro Tagliatesta, Chiara Lorecchio, Lorenzo Stella, Saulius Kaciulis, Peiman Soltani, Ernesto Placidi, Roberto Pizzoferrato
A novel type of graphene-like nanoparticle, synthesized by oxidation and unfolding of C60 buckminsterfullerene fullerene, showed multiple and reproducible sensitivity to Cu2+ , Pb2+ , Cd2+ , and As(III) through different degrees of fluorescence quenching or, in the case of Cd2+ , through a remarkable fluorescence enhancement. Most importantly, only for Cu2+ and Pb2+ , the fluorescence intensity variations came with distinct modifications of the optical absorption spectrum. Time-resolved fluorescence study confirmed that the common origin of these diverse behaviors lies in complexation of the metal ions by fullerene-derived carbon layers, even though further studies are required for a complete explanation of the involved processes...
May 10, 2018: Sensors
https://www.readbyqxmd.com/read/29747374/use-of-the-stockwell-transform-in-the-detection-of-p300-evoked-potentials-with-low-cost-brain-sensors
#11
Alan F Pérez-Vidal, Carlos D Garcia-Beltran, Albino Martínez-Sibaja, Rubén Posada-Gómez
The evoked potential is a neuronal activity that originates when a stimulus is presented. To achieve its detection, various techniques of brain signal processing can be used. One of the most studied evoked potentials is the P300 brain wave, which usually appears between 300 and 500 ms after the stimulus. Currently, the detection of P300 evoked potentials is of great importance due to its unique properties that allow the development of applications such as spellers, lie detectors, and diagnosis of psychiatric disorders...
May 9, 2018: Sensors
https://www.readbyqxmd.com/read/29743531/identifying-suicide-ideation-and-suicidal-attempts-in-a-psychiatric-clinical-research-database-using-natural-language-processing
#12
Andrea C Fernandes, Rina Dutta, Sumithra Velupillai, Jyoti Sanyal, Robert Stewart, David Chandran
Research into suicide prevention has been hampered by methodological limitations such as low sample size and recall bias. Recently, Natural Language Processing (NLP) strategies have been used with Electronic Health Records to increase information extraction from free text notes as well as structured fields concerning suicidality and this allows access to much larger cohorts than previously possible. This paper presents two novel NLP approaches - a rule-based approach to classify the presence of suicide ideation and a hybrid machine learning and rule-based approach to identify suicide attempts in a psychiatric clinical database...
May 9, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29739221/crystal-nucleation-and-metastable-bcc-phase-in-charged-colloids-a-molecular-dynamics-study
#13
Xinqiang Ji, Zhiwei Sun, Wenze Ouyang, Shenghua Xu
The dynamic process of homogenous nucleation in charged colloids is investigated by brute-force molecular dynamics simulation. To check if the liquid-solid transition will pass through metastable bcc, simulations are performed at the state points that definitely lie in the phase region of thermodynamically stable fcc. The simulation results confirm that, in all of these cases, the preordered precursors, acting as the seeds of nucleation, always have predominant bcc symmetry consistent with Ostwald's step rule and the Alexander-McTague mechanism...
May 7, 2018: Journal of Chemical Physics
https://www.readbyqxmd.com/read/29738474/multiband-envelope-spectra-extraction-for-fault-diagnosis-of-rolling-element-bearings
#14
Jie Duan, Tielin Shi, Hongdi Zhou, Jianping Xuan, Yongxiang Zhang
Bearing fault features are presented as repetitive transient impulses in vibration signals. Narrowband demodulation methods have been widely used to extract the repetitive transients in bearing fault diagnosis, for which the key factor is to accurately locate the optimal band. A multitude of criteria have been constructed to determine the optimal frequency band for demodulation. However, these criteria can only describe the strength of transient impulses, and cannot differentiate fault-related impulses and interference impulses that are cyclically generated in the signals...
May 8, 2018: Sensors
https://www.readbyqxmd.com/read/29737432/assessment-of-sudomotor-function
#15
REVIEW
Sylvia J Buchmann, Ana Isabel Penzlin, Marie Luise Kubasch, Ben Min-Woo Illigens, Timo Siepmann
PURPOSE: To review the currently available literature on clinical autonomic tests of sudomotor function. METHODS: We searched PubMED/MEDLINE for articles on technical principles and clinical applications of sudomotor tests with a focus on their drawbacks and perspectives in order to provide a narrative review. RESULTS: The quantitative sudomotor axon reflex sweat test (QSART) is the most widely used test of sudomotor function. The technique captures pathology with low intra- and inter-subject variability but is limited by technical demands...
May 8, 2018: Clinical Autonomic Research: Official Journal of the Clinical Autonomic Research Society
https://www.readbyqxmd.com/read/29737313/laparoscopic-management-of-a-case-of-accessory-gall-bladder-with-review-of-literature
#16
Guru Prasad Painuly, Ankur Gupta, Mini Singhal, Bhavna Bansal
Gall bladder duplication is a rare congenital anomaly. True duplication is still rarer. Pre-operative detection helps in avoiding complications or missing the gall bladder during surgery. Ultrasonography (USG) and magnetic resonance cholangiography are investigation of choice. Laparoscopic cholecystectomy is the preferred modality for management of double gall bladder. We present a case diagnosed as cholelithiasis on USG. While doing laparoscopic surgery 2 gall bladders were found. She had a normal gall bladder that was lying in the supraduodenal area...
May 4, 2018: Journal of Minimal Access Surgery
https://www.readbyqxmd.com/read/29734806/dual-emission-through-thermally-activated-delayed-fluorescence-and-room-temperature-phosphorescence-and-their-thermal-enhancement-via-solid-state-structural-change-in-a-carbazole-quinoline-conjugate
#17
Indranil Bhattacharjee, Nirmalya Acharya, Harsh Bhatia, Debdas Ray
The emergence of single-component organic dual light emitters holds great promise for white light-emitting diodes (WLEDs) and biological detection due to the involvement of broad emission covering visible spectrum. Here we show experimental studies on dual emission of carbazole-quinoline conjugate (CQ) that exhibits both thermally activated delayed fluorescence (TADF) via reverse intersystem crossing (rISC) from the higher-lying triplet state ( T2 ) to the singlet state ( S1 ) and room-temperature phosphorescence (RTP) from the lowest triplet state ( T1 ) due to low energy gap between T2 and S1 , and energetic proximity of T1 with T2 ...
May 7, 2018: Journal of Physical Chemistry Letters
https://www.readbyqxmd.com/read/29734089/magnetic-luminescent-cerium-doped-gadolinium-aluminum-garnet-nanoparticles-for-simultaneous-imaging-and-photodynamic-therapy-of-cancer-cells
#18
Akhil Jain, Rina Koyani, Carlos Muñoz, Prakhar Sengar, Oscar E Contreras, Patricia Juárez, Gustavo A Hirata
Nanoparticle (NP) and photosensitizer (PS) conjugates capable of X-ray photodynamic therapy (X-PDT) are a research focus due to their potential applications in cancer treatment. Combined with X-PDT, appropriate imaging properties of the nanocomposite will make it suitable for theranostics of deep lying tumors. In this work, we describe the development of magnetic-luminescent Gd2.98 Ce0.02 Al5 O12 nanoparticles (GAG) coated with mesoporous silica (mSiO2 ) and loaded with rose bengal (RB) to yield a nanocomposite GAG@mSiO2 @RB capable of X-PDT...
April 27, 2018: Journal of Colloid and Interface Science
https://www.readbyqxmd.com/read/29730498/computer-aided-detection-of-ureteral-stones-in-thin-slice-computed-tomography-volumes-using-convolutional-neural-networks
#19
Martin Längkvist, Johan Jendeberg, Per Thunberg, Amy Loutfi, Mats Lidén
Computed tomography (CT) is the method of choice for diagnosing ureteral stones - kidney stones that obstruct the ureter. The purpose of this study is to develop a computer aided detection (CAD) algorithm for identifying a ureteral stone in thin slice CT volumes. The challenge in CAD for urinary stones lies in the similarity in shape and intensity of stones with non-stone structures and how to efficiently deal with large high-resolution CT volumes. We address these challenges by using a Convolutional Neural Network (CNN) that works directly on the high resolution CT volumes...
April 27, 2018: Computers in Biology and Medicine
https://www.readbyqxmd.com/read/29729312/molecular-and-biological-characterization-of-gamma-interferon-inducible-lysosomal-thiol-reductase-in-silver-carp-hypophthalmichthys-molitrix
#20
Fang Cao, Haitao Wu, Tongtong Lv, Yunqing Yang, Yue Li, Shuaimei Liu, Lingling Hu, Xixi Xu, Lie Ma, Xinyi Zhang, Jianfeng Li, Xiaolin Bi, Wei Gu, Shuangquan Zhang
Gamma-interferon-inducible lysosomal thiol reductase (GILT) plays an important role in the processing of major histocompatibility complex (MHC) class II-restricted antigens by catalyzing disulfide bonds reduction. Herein, a GILT homolog (ScGILT) was identified from silver carp. Its open reading frame covers 771 base pairs, encoding a protein of 256 amino acids that possesses GILT signature sequence CQHGX2 ECX2 NX4 C, active-site CXXC motif, and two potential N-linked glycosylation sites. The predicted tertiary structures of ScGILT and other GILTs were quite similar in shape and positional arrangement of the key motifs...
May 2, 2018: Fish & Shellfish Immunology
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