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viral meningoencephalitis review

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https://www.readbyqxmd.com/read/28762591/ean-consensus-review-on-prevention-diagnosis-and-management-of-tick-borne-encephalitis
#1
REVIEW
P Taba, E Schmutzhard, P Forsberg, I Lutsar, U Ljøstad, Å Mygland, I Levchenko, F Strle, I Steiner
BACKGROUND AND PURPOSE: Tick-borne encephalitis (TBE) is an infection of the central nervous system (CNS) caused by tick-borne encephalitis virus (TBEV) and transmitted by ticks, with a variety of clinical manifestations. The incidence of TBE in Europe is increasing due to an extended season of the infection and the enlargement of endemic areas. Our objectives are to provide recommendations on the prevention, diagnosis and management of TBE, based on evidence or consensus decisions. METHODS: For systematic evaluation, the literature was searched from 1970 to 2015 (including early online publications of 2016), and recommendations were based on evidence or consensus decisions of the Task Force when evidence-based data were not available...
August 1, 2017: European Journal of Neurology: the Official Journal of the European Federation of Neurological Societies
https://www.readbyqxmd.com/read/28636287/the-spectrum-of-aseptic-central-nervous-system-infections-in-southern-germany-demographic-clinical-and-laboratory-findings
#2
M Kaminski, V Grummel, D Hoffmann, A Berthele, B Hemmer
BACKGROUND AND PURPOSE: Aseptic infections of the central nervous system (CNS) are frequently observed in Germany. However, no study has systematically addressed the spectrum of aseptic CNS infections in Germany. METHODS: Data on 191 adult patients diagnosed from January 2007 to December 2014 with aseptic meningitis or encephalitis/meningoencephalitis at our hospital were collected by chart review and analyzed for demographic, clinical and laboratory findings. Patients were stratified according to the causative virus and findings were compared between groups...
June 21, 2017: European Journal of Neurology: the Official Journal of the European Federation of Neurological Societies
https://www.readbyqxmd.com/read/28632511/zika-virus-a-cause-of-concern-in-transplantation
#3
Marilyn E Levi
PURPOSE OF REVIEW: Worldwide, the number of countries reporting Zika virus (ZKV) infection continues to increase. Although 80% of cases are asymptomatic, ZKV has been identified as a neurotropic virus associated with congenital microcephaly, Guillain-Barre' syndrome, and meningoencephalitis. Until recently, infection in transplant recipients has not been identified. This study will review the existing literature on ZKV infection, laboratory testing, and management in transplant recipients...
August 2017: Current Opinion in Infectious Diseases
https://www.readbyqxmd.com/read/28630845/multi-foci-salmonella-enteritis-osteomyelitis-of-thoracic-spine-with-pleural-effusion-and-fatal-outcome-a-unique-case-presentation-and-review-of-the-literature
#4
Ioannis Papaioannou, Andreas Baikousis, Panagiotis Korovessis
INTRODUCTION: A case of thoracic vertebral osteomyelitis due to Salmonella enteritis (SE) in an immunocompetent patient is reported. This is the third case in the literature of SE thoracic vertebral osteomyelitis, but the first one with this multi-foci presentation and finally fatal outcome due to meningoencephalitis. Further data that makes our case unique are the absence of fever (body temperature: 37.4°C) and gastrointestinal disorders. CASE REPORT: A 57-year-old male patient initially presented with thoracic pain, dyspnea, and knee pain...
January 2017: Journal of Orthopaedic Case Reports
https://www.readbyqxmd.com/read/28382855/natural-infections-with-pigeon-paramyxovirus-serotype-1-pathologic-changes-in-eurasian-collared-doves-streptopelia-decaocto-and-rock-pigeons-columba-livia-in-the-united-states
#5
M Isidoro-Ayza, C L Afonso, J B Stanton, S Knowles, H S Ip, C L White, H Fenton, M G Ruder, A C Dolinski, J Lankton
Pigeon paramyxovirus serotype 1 (PPMV-1) is a globally distributed, virulent member of the avian paramyxovirus serotype 1 serogroup that causes mortality in columbiformes and poultry. Following introduction into the United States in the mid-1980s, PPMV-1 rapidly spread causing numerous mortality events in Eurasian collared-doves ( Streptopelia decaocto) (ECDOs) and rock pigeons ( Columba livia) (ROPIs). The investigators reviewed pathological findings of 70 naturally infected, free-ranging columbiforms from 25 different mortality events in the United States...
July 2017: Veterinary Pathology
https://www.readbyqxmd.com/read/28108286/the-impact-of-zika-virus-in-the-brain
#6
Fabiele Baldino Russo, Patricia Cristina Baleeiro Beltrão-Braga
The recent outbreak of ZIKV in Brazil called the attention of the world because the effects of viral infection in the brain under development in fetuses. Consequences of vertical infection comprise brain malformation, especially microcephaly, eye and musculoskeletal abnormalities, among others. In adults, outcomes of infection include meningoencephalitis and Guillain-Barré Syndrome. Recent data specific suggest that neural progenitor cells are the main targets of ZIKV infection, causing massive cellular death and impairment in the neurogenesis process...
January 17, 2017: Biochemical and Biophysical Research Communications
https://www.readbyqxmd.com/read/27889719/causes-of-death-among-children-aged-5-years-in-a-public-hospital-in-new-delhi
#7
Manas Pratim Roy, Ratan Gupta, Meenakshi Bhatt, Kailash Chander Aggarwal
Retrospective analysis was done for 3817 children aged 5-12 years admitted in a tertiary-care, public hospital in New Delhi between January to December, 2015. Mortality rate was 5.8%. About 47.1% deaths were due to central nervous system involvement; viral meningoencephalitis being the predominant cause. Overall, infectious diseases caused >80% of deaths. Public health interventions to reduce child mortality need to review such data for effective measures.
January 15, 2017: Indian Pediatrics
https://www.readbyqxmd.com/read/27819416/neurological-manifestations-of-acute-posterior-multifocal-placoid-pigment-epitheliopathy
#8
Hussein Algahtani, Ashjan Alkhotani, Bader Shirah
BACKGROUND AND PURPOSE: Acute posterior multifocal placoid pigment epitheliopathy (APMPPE) is an immune-mediated chorioretinal disease that causes acute visual symptoms with characteristic ophthalmoscopic findings. Neurological complications are rarely reported in the literature. Here we report two new cases of APMPPE that presented with neurological manifestations, one of which was associated with peripheral neuropathy, which has not been described before. METHODS: A retrospective database review of all patients with a diagnosis of APMPPE was performed...
October 2016: Journal of Clinical Neurology
https://www.readbyqxmd.com/read/27736668/blood-csf-barrier-dysfunction-is-a-marker-for-encephalitic-involvement-in-patients-with-aseptic-meningitis-meningoencephalitis
#9
C Hoyer, P Eisele, A D Ebert, S Schneider, A Gass, M Fatar, K Szabo, A Alonso
BACKGROUND: The term "aseptic meningitis" encompasses cases of meningitis with negative bacterial CSF culture, which predominantly are of viral etiology. While the clinical course is usually benign, complications such as encephalitic involvement resulting in a more severe clinical course may occur. Dysfunction of the blood-brain-barrier (BBB), which is a prerequisite for viral entry into the brain parenchyma, can be approximated using the CSF/serum albumin ratio, readily obtainable in routine CSF analysis...
November 2016: Journal of Clinical Virology: the Official Publication of the Pan American Society for Clinical Virology
https://www.readbyqxmd.com/read/27734521/enteroviral-infection-in-patients-treated-with-rituximab-for-non-hodgkin-lymphoma-a-case-series-and-review-of-the-literature
#10
S Grisariu, I Vaxman, M Gatt, S Elias, B Avni, A Arad, O Pasvolsky, P Raanani, O Paltiel
In recent years, anti-CD20 antibodies have been increasingly used to treat lymphoproliferative and immune disorders. Chronic viral infections are infrequently reported in patients receiving these therapies. Enteroviral infection can cause life-threatening meningoencephalitis and other systemic chronic syndromes in immune deficient patients. We describe the clinical courses and outcomes of 6 patients from 2 tertiary care institutions who developed chronic enteroviral infection with neurological manifestations, after combined chemoimmunotherapy with rituximab for B-cell lymphoma...
October 13, 2016: Hematological Oncology
https://www.readbyqxmd.com/read/27320588/ganciclovir-and-foscarnet-therapy-of-cytomegalovirus-associated-meningoencephalitis-in-a-hemodialysis-patient-with-liver-transplantation-case-report
#11
G W Kang, H L Hong, I H Lee, K S Ahn, J D Kim, D L Choi
Cytomegalovirus (CMV) infection in patients with liver transplantation (LT) remains a highly prevalent complication with a significant increase in morbidity and mortality. However, CMV-associated meningoencephalitis is rarely diagnosed, and treatment is very difficult. The aim of the present report is to review the experience of successful treatment with combined ganciclovir and foscarnet of CMV-associated meningoencephalitis refractory to ganciclovir alone in a hemodialysis (HD) patient after LT. A 54-year-old woman with end-stage renal disease on HD developed a seizure with loss of consciousness...
May 2016: Transplantation Proceedings
https://www.readbyqxmd.com/read/27137084/cytomegalovirus-encephalitis-undescribed-diffusion-weighted-imaging-characteristics-original-aspects-of-cases-extracted-from-a-retrospective-study-and-from-literature-review
#12
Thibaut Renard, Benjamin Daumas-Duport, Elisabeth Auffray-Calvier, Romain Bourcier, Hubert Desal
INTRODUCTION: There is paucity of studies analyzing DWI in MRI sequences when imaging cytomegalovirus (CMV) meningoencephalitis. The main objective of this study is to demonstrate that DWI sequence is mandatory when imaging immunocompromised patients presenting with encephalitic symptoms, as this sequence can reveal very peculiar lesions in the setting of CMV encephalitis. PATIENTS AND METHOD: Three CSF PCR CMV positive cases were identified in a 13-year retrospective study with MRI scans including T1, FLAIR, DWI with automated ADC calculation, and T1 with contrast injection, and were reviewed by a senior neuroradiologist...
December 2016: Journal of Neuroradiology. Journal de Neuroradiologie
https://www.readbyqxmd.com/read/27086496/la-crosse-encephalitis-an-adult-case-series
#13
Amy Lynn A Teleron, Brandon K Rose, David M Williams, Suzanne E Kemper, James E McJunkin
BACKGROUND: La Crosse viral encephalitis is well described in children, but to date, there are only 2 adult cases described in the literature. Despite the fact that pediatric infection can be life threatening and typically presents as a febrile meningoencephalitis often complicated by seizures and mental status changes, little is known about the presentation and course of adult infection. We report the largest case series of adult La Crosse encephalitis. METHODS: Inpatient data were reviewed between 2001 and 2012 to identify adults (≥18 years of age) with possible La Crosse encephalitis...
August 2016: American Journal of Medicine
https://www.readbyqxmd.com/read/26342975/the-role-of-micrornas-in-enteroviral-infections
#14
REVIEW
Jing Wu, Li Shen, Jianguo Chen, Huaxi Xu, Lingxiang Mao
The genus Enterovirus, a member of the Picornavirus family, are RNA viruses that can cause poliomyelitis, hand-food-mouth disease, viral meningitis or meningoencephalitis, viral myocarditis and so on. MicroRNAs are a class of highly conserved, small noncoding RNAs recognized as important regulators of gene expression. Recent studies found that MicroRNAs play a significant role in the infection of Enterovirus, such as enterovirus 71, coxsackievirus B3 and other Enterovirus. Enteroviral infection can alter the expression of cellular MicroRNAs, and cellular MicroRNAs can modulate viral pathogenesis and replication by regulating the expression level of viral or host's genes...
September 2015: Brazilian Journal of Infectious Diseases
https://www.readbyqxmd.com/read/26121728/iap-position-paper-on-burden-of-mumps-in-india-and-vaccination-strategies
#15
Vipin M Vashishtha, Sangeeta Yadav, Aashima Dabas, C P Bansal, Rohit C Agarwal, Vijay N Yewale, Naveen Thacker, S S Kamath, Pravin J Mehta
JUSTIFICATION: Mumps, despite being a widely prevalent disease in the country, is considered as an insignificant public health problem mainly because of poor documentation of clinical cases and lack of published studies. In the absence of adequate published data on disease burden, Government of India has recently decided to introduce measles-rubella (MR) vaccine in its National Immunization Program and neglected mumps component. PROCESS: Following an IAP ACVIP meeting on December 6 and 7, 2014, a detailed review of burden of mumps in India along with vaccination strategies to control the disease was prepared...
June 2015: Indian Pediatrics
https://www.readbyqxmd.com/read/25574400/type-i-diabetes-mellitus-genetic-factors-and-presumptive-enteroviral-etiology-or-protection
#16
REVIEW
Jana Precechtelova, Maria Borsanyiova, Sona Sarmirova, Shubhada Bopegamage
We review type 1 diabetes and host genetic components, as well as epigenetics and viruses associated with type 1 diabetes, with added emphasis on the enteroviruses, which are often associated with triggering the disease. Genus Enterovirus is classified into twelve species of which seven (Enterovirus A, Enterovirus B, Enterovirus C, and Enterovirus D and Rhinovirus A, Rhinovirus B, and Rhinovirus C) are human pathogens. These viruses are transmitted mainly by the fecal-oral route; they may also spread via the nasopharyngeal route...
2014: Journal of Pathogens
https://www.readbyqxmd.com/read/24892851/clinical-and-laboratory-characteristics-of-central-nervous-system-herpes-simplex-virus-infection-in-neonates-and-young-infants
#17
David Kotzbauer, Deborah Andresen, Nancy Doelling, Steve Shore
We reviewed the characteristics of infants <3 months of age with central nervous system herpes simplex virus infection at our institution. Twenty-six cases were identified. The age range was 4-73 days. Most infants presented with fever, seizure activity and skin lesions. The blood herpes simplex virus polymerase chain reaction was positive in 91% of patients tested. Suppressive oral acyclovir therapy was likely helpful in preventing disease recurrence.
November 2014: Pediatric Infectious Disease Journal
https://www.readbyqxmd.com/read/24792344/neurological-complications-of-varicella-zoster-virus-reactivation
#18
REVIEW
Maria A Nagel, Don Gilden
PURPOSE OF REVIEW: Varicella zoster virus (VZV) reactivation results in zoster, which may be complicated by postherpetic neuralgia, myelitis, meningoencephalitis, and VZV vasculopathy. This review highlights the clinical features, laboratory abnormalities, imaging changes, and optimal treatment of each of those conditions. Because all of these neurological disorders produced by VZV reactivation can occur in the absence of rash, the virological tests proving that VZV caused disease are discussed...
June 2014: Current Opinion in Neurology
https://www.readbyqxmd.com/read/24598831/steroid-responsive-encephalopathy-associated-with-autoimmune-thyroiditis-sreat-in-childhood
#19
REVIEW
Saroj Kumar Patnaik, Vimal Upreti, Pawan Dhull
AIM: Steroid responsive encephalopathy with autoimmune thyroiditis (SREAT) is a clinically and electrographically heterogeneous steroid-responsive encephalopathy associated with thyroid autoantibodies. We report an adolescent with SREAT and review PubMed literature relating to childhood. METHODS: A 14-year-old boy, without any preceding history of trauma, meningoencephalitis or seizures, was admitted in a comatose state. A similar episode of loss of consciousness 2 months prior with normal neuroimaging and electroencephalogram (EEG) had been followed by behavioral alterations...
July 2014: Journal of Pediatric Endocrinology & Metabolism: JPEM
https://www.readbyqxmd.com/read/24555792/association-between-neuromyelitis-optica-and-tuberculosis-in-a-chinese-population
#20
Rui Li, Xiaonan Zhong, Wei Qiu, Aimin Wu, Yongqiang Dai, Zhengqi Lu, Xueqiang Hu
BACKGROUND: A number of reports have described the presence of tuberculosis (TB) in neuromyelitis optica (NMO) patients. However, a definite association between the two conditions has not been conclusively demonstrated. METHODS: To investigate the association between NMO and TB in a Chinese population, we performed a retrospective review of hospital records of NMO patients, control patients and tuberculosis meningitis (TBM) patients from January 1, 1995 to December 31, 2011...
February 20, 2014: BMC Neurology
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