keyword
MENU ▼
Read by QxMD icon Read
search

Treatment of bipolar disorder

keyword
https://www.readbyqxmd.com/read/28633719/a-case-of-recurrent-hypersomnia-with-autonomic-dysfunction
#1
Mandana Mahmoudi, Daniel Friedman, Martina Vendrame, Sanjeev V Kothare
We report the case of a 50-year-old man with disabling recurrent hypersomnia with autonomic instability due to catatonia in the setting of atypical bipolar disorder. Treatment with valproic acid for bipolar disorder resulted in complete resolution of symptoms.
June 16, 2017: Journal of Clinical Sleep Medicine: JCSM: Official Publication of the American Academy of Sleep Medicine
https://www.readbyqxmd.com/read/28633054/men-and-women-with-psychosis-and-the-impact-of-illness-duration-on-sex-differences-the-second-australian-national-survey-of-psychosis
#2
Mary-Claire Hanlon, Linda E Campbell, Natalie Single, Clare Coleman, Vera A Morgan, Susan M Cotton, Helen J Stain, David J Castle
We aimed to examine and compare sex-differences in people receiving treatment for psychotic illnesses in community settings, based on long or short duration of illness; expecting association between longer illness-duration and worse outcomes in women and men. Clinical, demographic and service-use data from the Survey of High Impact Psychosis were analysed by sex and duration of illness (≤5 years; ≥6 years), using independent t-tests, chi-square tests, one-way ANOVA, and Cramer's V. Of the 1825 participants, 47% had schizophrenia, 17...
June 13, 2017: Psychiatry Research
https://www.readbyqxmd.com/read/28631584/clinical-characterization-of-italian-suicide-attempters-with-bipolar-disorder
#3
Bernardo Dell'Osso, Matteo Vismara, Cristina Dobrea, Laura Cremaschi, Benedetta Grancini, Chiara Arici, Beatrice Benatti, Massimiliano Buoli, Terence A Ketter, A Carlo Altamura
Introduction Bipolar disorder (BD) is a chronic, highly disabling condition associated with psychiatric/medical comorbidity and substantive morbidity, mortality, and suicide risks. In prior reports, varying parameters have been associated with suicide risk. OBJECTIVES: To evaluate sociodemographic and clinical variables characterizing Italian individuals with BD with versus without prior suicide attempt (PSA). METHODS: A sample of 362 Italian patients categorized as BD according to the Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition, Text Revision (DSM IV-TR) was assessed and divided in 2 subgroups: with and without PSA...
June 20, 2017: CNS Spectrums
https://www.readbyqxmd.com/read/28629957/chemical-hand-warmer-packet-ingestion-a-case-of-elemental-iron-exposure
#4
Jessica L Weiland, Leighanne K Sherrow, Deepak A Jayant, Kenneth D Katz
For individuals who work outdoors in the winter or play winter sports, chemical hand warmers are becoming increasingly more commonplace because of their convenience and effectiveness. A 32-year-old woman with a history of chronic pain and bipolar disorder presented to the emergency department complaining of a "warm sensation" in her mouth and epigastrium after reportedly ingesting the partial contents of a chemical hand warmer packet containing between 5 and 8 g of elemental iron. She had been complaining of abdominal pain for approximately 1 month and was prescribed unknown antibiotics the previous day...
June 16, 2017: Wilderness & Environmental Medicine
https://www.readbyqxmd.com/read/28629296/atypical-antipsychotic-use-and-outcomes-in-an-urban-maternal-mental-health-service
#5
Susan Hatters Friedman, Charmian Moller-Olsen, Chandni Prakash, Abigail North
Objective Despite many women suffering from psychosis in their childbearing years, limited data exist about the use of atypical antipsychotic agents in pregnancy. Atypical antipsychotic agents are often used to treat bipolar disorder, instead of lithium or valproate because of the known teratogenicity of those agents. As well, atypical antipsychotics are often prescribed in anxiety disorders and depression. This study sought to describe pregnancy outcomes for women prescribed atypical antipsychotics during pregnancy...
August 2016: International Journal of Psychiatry in Medicine
https://www.readbyqxmd.com/read/28628769/complex-psychotropic-polypharmacy-in-bipolar-disorder-across-varying-mood-polarities-a-prospective-cohort-study-of-2712-inpatients
#6
Julia C Golden, John W Goethe, Stephen B Woolley
BACKGROUND: It is common for patients with bipolar disorder (BP) to receive multiple psychotropics, but few studies have assessed demographic and clinical features associated with risk for receiving complex psychotropic polypharmacy. METHODS: This longitudinal cohort study examined 2712 inpatients with a DSM-IV clinical diagnosis of BP to assess associations between complex polypharmacy (defined as ≥4 psychotropics) and demographic and clinical features; associations with risk of rehospitalization were also examined...
June 13, 2017: Journal of Affective Disorders
https://www.readbyqxmd.com/read/28625858/stem-cells-pluripotency-and-glial-cell-markers-in-peripheral-blood-of-bipolar-patients-on-long-term-lithium-treatment
#7
REVIEW
Ewa Ferensztajn-Rochowiak, Jolanta Kucharska-Mazur, Maciej Tarnowski, Jerzy Samochowiec, Mariusz Z Ratajczak, Janusz K Rybakowski
BACKGROUND: We investigated the effect of long-term lithium treatment on very-small embryonic-like stem cells (VSELs) and the mRNA expression of pluripotency and glial markers, in peripheral blood, in patients with bipolar disorder (BD). METHODS: Fifteen BD patients (aged 53±7years) not treated with lithium, with duration of illness >10years, 15 BD patients (aged 55±6years) treated with lithium for 8-40years (mean 16years) and 15 control subjects (aged 50±5years) were included...
June 15, 2017: Progress in Neuro-psychopharmacology & Biological Psychiatry
https://www.readbyqxmd.com/read/28622159/weeding-out-the-justification-for-marijuana-treatment-in-patients-with-developmental-and-behavioral-conditions
#8
Theodora Nelson, Yi Hui Liu, Kara S Bagot, Martin T Stein
Alex is a 13-year-old adolescent with high-functioning autism spectrum disorder, attention-deficit/hyperactivity disorder (ADHD)-combined type, anxiety, and depression. He has been resistant to engaging in therapy and treatment with various medications has been unsuccessful. Alex's parents are concerned about his anxiety, isolation, oppositional behaviors, academic underachievement, truancy, and substance use. A recent altercation with his stepfather led to a police intervention and a brief removal of Alex from the home...
June 15, 2017: Journal of Developmental and Behavioral Pediatrics: JDBP
https://www.readbyqxmd.com/read/28621662/chronic-lithium-treatment-elicits-its-antimanic-effects-via-bdnf-trkb-dependent-synaptic-downscaling
#9
Erinn S Gideons, Pei-Yi Lin, Melissa Mahgoub, Ege T Kavalali, Lisa M Monteggia
Lithium is widely used as a treatment for Bipolar Disorder although the molecular mechanisms that underlie its therapeutic effects are under debate. In this study, we show brain-derived neurotrophic factor (BDNF) is required for the antimanic-like effects of lithium but not the antidepressant-like effects in mice. We performed whole cell patch clamp recordings of hippocampal neurons to determine the impact of lithium on synaptic transmission that may underlie the behavioral effects. Lithium produced a significant decrease in α-amino-3-hydroxyl-5-methyl-4-isoxazolepropionic acid receptor (AMPAR)-mediated miniature excitatory postsynaptic current (mEPSC) amplitudes due to postsynaptic homeostatic plasticity that was dependent on BDNF and its receptor tropomyosin receptor kinase B (TrkB)...
June 16, 2017: ELife
https://www.readbyqxmd.com/read/28620239/shared-and-specific-intrinsic-functional-connectivity-patterns-in-unmedicated-bipolar-disorder-and-major-depressive-disorder
#10
Ying Wang, Junjing Wang, Yanbin Jia, Shuming Zhong, Meiqi Niu, Yao Sun, Zhangzhang Qi, Ling Zhao, Li Huang, Ruiwang Huang
Identifying brain differences and similarities between bipolar disorder (BD) and major depressive disorder (MDD) is necessary for increasing our understanding of the pathophysiology and for developing more effective treatments. However, the features of whole-brain intrinsic functional connectivity underlying BD and MDD have not been directly compared. We collected resting-state fMRI data from 48 BD patients, 48 MDD patients, and 51 healthy subjects. We constructed voxel-wise whole-brain functional networks and computed regional functional connectivity strength (FCS) using graph-theory and further divided the regional FCS into long-range FCS (lFCS) and short-range FCS (sFCS)...
June 15, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28619114/reducing-the-rate-and-duration-of-re-admissions-among-patients-with-unipolar-disorder-and-bipolar-disorder-using-smartphone-based-monitoring-and-treatment-the-radmis-trials-study-protocol-for-two-randomized-controlled-trials
#11
Maria Faurholt-Jepsen, Mads Frost, Klaus Martiny, Nanna Tuxen, Nicole Rosenberg, Jonas Busk, Ole Winther, Jakob Eyvind Bardram, Lars Vedel Kessing
BACKGROUND: Unipolar and bipolar disorder combined account for nearly half of all morbidity and mortality due to mental and substance use disorders, and burden society with the highest health care costs of all psychiatric and neurological disorders. Among these, costs due to psychiatric hospitalization are a major burden. Smartphones comprise an innovative and unique platform for the monitoring and treatment of depression and mania. No prior trial has investigated whether the use of a smartphone-based system can prevent re-admission among patients discharged from hospital...
June 15, 2017: Trials
https://www.readbyqxmd.com/read/28617434/lispro-mitigates-%C3%AE-amyloid-and-associated-pathologies-in-alzheimer-s-mice
#12
Ahsan Habib, Darrell Sawmiller, Song Li, Yang Xiang, David Rongo, Jun Tian, Huayan Hou, Jin Zeng, Adam Smith, Shengnuo Fan, Brian Giunta, Takashi Mori, Glenn Currier, Douglas Ronald Shytle, Jun Tan
Lithium has been marketed in the United States of America since the 1970s as a treatment for bipolar disorder. More recently, studies have shown that lithium can improve cognitive decline associated with Alzheimer's disease (AD). However, the current United States Food and Drug Administration-approved lithium pharmaceutics (carbonate and citrate chemical forms) have a narrow therapeutic window and unstable pharmacokinetics that, without careful monitoring, can cause serious adverse effects. Here, we investigated the safety profile, pharmacokinetics, and therapeutic efficacy of LISPRO (ionic co-crystal of lithium salicylate and l-proline), lithium salicylate, and lithium carbonate (Li2CO3)...
June 15, 2017: Cell Death & Disease
https://www.readbyqxmd.com/read/28616860/insomnia-as-a-precipitating-factor-in-new-onset-mental-illness-a-systematic-review-of-recent-findings
#13
REVIEW
Wilfred R Pigeon, Todd M Bishop, Kelsey M Krueger
PURPOSE: We aimed to systematically review recent publications (01/2014-03/2017) with longitudinal designs allowing for the assessment of the prospective risk of insomnia on new onset mental illness in key conditions: anxiety, depression, bipolar disorder, posttraumatic stress disorder, substance use disorders, and suicide. RECENT FINDINGS: A literature yielded 1859 unique articles meeting search criteria were identified; 16 articles met all selection criteria and reviewed with some studies reporting on more than one mental health outcome...
August 2017: Current Psychiatry Reports
https://www.readbyqxmd.com/read/28616776/evidence-towards-rna-binding-motif-rnp1-rrm-protein-3-rbm3-as-a-potential-biomarker-of-lithium-response-in-bipolar-disorder-patients
#14
Eleni Merkouri Papadima, Paola Niola, Carla Melis, Claudia Pisanu, Donatella Congiu, Cristiana Cruceanu, Juan Pablo Lopez, Gustavo Turecki, Raffaella Ardau, Giovanni Severino, Caterina Chillotti, Maria Del Zompo, Alessio Squassina
Lithium has been used for more than six decades for the management of bipolar disorder (BD). In a previous transcriptomic study, we showed that patients affected by either BD or cluster headache, both disorders characterized by circadian disturbances and response to lithium in a subgroup of patients, have higher expression of the RNA binding motif (RNP1, RRM) protein 3 (RBM3) gene compared to controls. To investigate whether RBM3 could represent a biomarker of lithium response, we screened raw microarray expression data from lymphoblastoid cell lines (LCLs) derived from 20 BD patients, responders or non-responders to lithium...
June 14, 2017: Journal of Molecular Neuroscience: MN
https://www.readbyqxmd.com/read/28615247/lithium-induced-ndi-acetazolamide-reduces-polyuria-but-does-not-improve-urine-concentrating-ability
#15
Theun de Groot, Joan Doornebal, Birgitte M Christensen, Simone C Cockx, Anne P Sinke, Ruben Baumgarten, Jennifer J Bedford, Robert J Walker, Jack F Wetzels, Peter M T Deen
Lithium is the mainstay treatment for patients with bipolar disorder, but generally causes nephrogenic diabetes insipidus (NDI), a disorder in which the renal urine concentrating ability has become vasopressin-insensitive. Li-NDI is caused by lithium uptake by collecting duct principal cells and downregulation of AQP2 water channels, which are essential for water uptake from pro-urine. Recently, we found that the prophylactic administration of acetazolamide to mice effectively attenuated Li-NDI. To evaluate whether acetazolamide might benefit lithium-treated patients, we administered acetazolamide to mice with established Li-NDI and six patients with a lithium-induced urinary concentrating defect...
June 14, 2017: American Journal of Physiology. Renal Physiology
https://www.readbyqxmd.com/read/28614493/bipolar-disorders-is-there-an-influence-of-seasonality-or-photoperiod
#16
Andrea Aguglia, Antonio Borsotti, Giuseppe Maina
Objective: To increase understanding of the influence of photoperiod variation in patients with bipolar disorders. Methods: We followed a sample of Italian bipolar patients over a period of 24 months, focusing on inpatients. All patients admitted to the Psychiatric Inpatient Unit of San Luigi Gonzaga Hospital in Orbassano (Turin, Italy) between September 1, 2013 and August 31, 2015 were recruited. Sociodemographic and clinical data were collected. Results: Seven hundred and thirty patients were included...
June 12, 2017: Revista Brasileira de Psiquiatria
https://www.readbyqxmd.com/read/28612993/melatonin-as-a-treatment-for-mood-disorders-a-systematic-review
#17
F De Crescenzo, A Lennox, J C Gibson, J H Cordey, S Stockton, P J Cowen, D J Quested
OBJECTIVE: Melatonin has been widely studied in the treatment of sleep disorders and evidence is accumulating on a possible role for melatonin influencing mood. Our aim was to determine the efficacy and acceptability of melatonin for mood disorders. METHOD: We conducted a comprehensive systematic review of randomized clinical trials on patients with mood disorders, comparing melatonin to placebo. RESULTS: Eight clinical trials were included; one study in bipolar, three in unipolar depression and four in seasonal affective disorder...
June 14, 2017: Acta Psychiatrica Scandinavica
https://www.readbyqxmd.com/read/28612977/characteristics-of-depression-among-offspring-at-high-and-low-familial-risk-of-bipolar-disorder
#18
Rasim Somer Diler, Tina R Goldstein, Danella Hafeman, Brian Thomas Rooks, Dara Sakolsky, Benjamin I Goldstein, Kelly Monk, Mary Beth Hickey, David Axelson, Satish Iyengar, Boris Birmaher
OBJECTIVES: Having a parent with bipolar disorder (BP) is a very strong risk factor for developing BP. Similarly, depression among youth is a clinical risk factor for subsequent BP. We evaluated whether mood symptomatology in depressed youth is different between those at high and low familial risk to develop BP. METHODS: The most severe major depressive episode in BP offspring (N=61) and community control offspring (N=20) was evaluated using expanded depression and mania rating scales derived from the Schedule for Affective Disorders and Schizophrenia for Children Present Version...
June 14, 2017: Bipolar Disorders
https://www.readbyqxmd.com/read/28612649/a-brain-on-a-roller-coaster-can-the-dopamine-reward-system-act-as-a-protagonist-to-subdue-the-ups-and-downs-of-bipolar-disorder
#19
Shokouh Arjmand, Mina Behzadi, Gary J Stephens, Sara Ezzatabadipour, Rostam Seifaddini, Shahrad Arjmand, Mohammad Shabani
One of the most interesting but tenebrous parts of the bipolar disorder (BD) story is the switch between (hypo)mania and depression, which can give bipolar patients a thrilling, but somewhat perilous, 'ride'. Numerous studies have pointed out that there are some recognizable differences (either state-dependent or state-independent) in several brain regions of people with BD, including components of the brain's reward system. Understanding the underpinning mechanisms of high and low mood statuses in BD has potential, not only for the development of highly specific and selective pharmaceutical agents, but also for better treatment approaches and psychological interventions to manage BD and, thus, give patients a safer ride...
June 1, 2017: Neuroscientist: a Review Journal Bringing Neurobiology, Neurology and Psychiatry
https://www.readbyqxmd.com/read/28610482/randomised-controlled-trial-of-a-healthy-lifestyle-intervention-among-smokers-with-psychotic-disorders-outcomes-to-36%C3%A2-months
#20
Amanda L Baker, Robyn Richmond, Frances J Kay-Lambkin, Sacha L Filia, David Castle, Jill M Williams, Terry J Lewin, Vanessa Clark, Robin Callister, Kerrin Palazzi
OBJECTIVE: People living with psychotic disorders (schizophrenia spectrum and bipolar disorders) have high rates of cardiovascular disease risk behaviours, including smoking, physical inactivity and poor diet. We report cardiovascular disease risk, smoking cessation and other risk behaviour outcomes over 36 months following recruitment into a two-arm randomised controlled trial among smokers with psychotic disorders. METHODS: Participants ( N = 235) drawn from three sites were randomised to receive nicotine replacement therapy plus (1) a Healthy Lifestyles intervention delivered over approximately 9 months or (2) a largely telephone-delivered intervention (designed to control for nicotine replacement therapy provision, session frequency and other monitoring)...
June 1, 2017: Australian and New Zealand Journal of Psychiatry
keyword
keyword
83268
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"