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cardiac interventions.valve disease.aorta.mitral.coronary

Tor Biering-Sørensen
BACKGROUND: The preservation of normal cardiac time intervals is intimately related to normal cardiac physiology and function. In the ailing myocardium, the cardiac time intervals will change during disease progression. As left ventricular (LV) systolic function deteriorates, the time it takes for myocardial myocytes to achieve an LV pressure equal to that of aorta increases, resulting in a prolongation of the isovolumic contraction time (IVCT). Furthermore, the ability of myocardial myocytes to maintain the LV pressure decreases, resulting in reduction in the ejection time (ET)...
August 2016: Danish Medical Journal
Paul P Urbanski, Mahli Raad, Matthias Wagner, Nicolas Heinz, Wilko Reents, Anno Diegeler
OBJECTIVES: New surgical and perfusion techniques allow the avoidance of deep hypothermia during open aortic arch surgery, which is generally necessary in patients with an unclampable porcelain aorta. The aim of the study was to evaluate operative and long-term results in patients with a porcelain aorta who underwent conventional cardiac surgery using current surgical and perfusion techniques. METHODS: Between November 2003 and February 2012, 30 consecutive patients (mean age 68 ± 11 years, 10 patients had previous cardiac surgery with use of glue in 5 of them) with porcelain aorta diagnosed by computed tomography and defined as a severe circular calcification of the proximal thoracic aorta were referred for cardiac surgery...
July 2013: European Journal of Cardio-thoracic Surgery
Hiroaki Miyata, Noboru Motomura, Hiroyuki Tsukihara, Shinichi Takamoto et al.
OBJECTIVE: While isolated coronary artery bypass grafting (CABG) poses major risks as well as benefits to cardiovascular surgery, procedures such as thoracic aortic surgery and combined CABG surgeries are also important contributors to mortality and morbidity. The objective of this study was to create and validate risk models including high-risk cardiovascular procedures to improve quality. METHODS: The Japan Cardiovascular Surgery Database of patients enrolled cardiovascular surgical patients between January 2005 and December 2007...
May 2011: European Journal of Cardio-thoracic Surgery
Iu V Belov, A B Stepanenko, A P Gens, E R Charchian, D D Savichev
Simultaneous surgical interventions on the aorta and valvular system of the heart were performed in four patients presenting with aortic dissections and aneurysms conditioned by Marfan's syndrome. The following reconstructive operations were carried out: 1) prosthetic repair of the aortic valve and the ascending portion of the aorta by means of a valve-containing conduit with replantation of the openings of the coronary arteries into the side of the prosthesis according to the Benthall - De Bono technique, annuloplasty of the tricuspid valve according to the De Vega technique, valvuloplasty of the mitral valve by the Alferi technique; 2) grafting of the aortic valve and the ascending portion of the aorta by means of a valve-containing conduit with replantation of the openings of the coronary arteries according to the Kabrol's technique, plasty of the tricuspid valve by the De Vega technique; 3) prosthetic repair of the aortic arch with distal wedge-like excision of the membrane of the dissection and directing the blood flow along the both channels, plasty of the mitral valve, plasty of the aortic valve and the ascending portion of the aorta with a valve-containing conduit, accompanied by replantation of the openings of the coronary arteries into the side of the graft according to the Benthall - De Bono technique; (4) plasty of the mitral valve with a disk graft through the fibrous ring of the aortic valve, prosthetic repair of the aortic valve and the ascending portion of the aorta with a valve-containing conduit, accompanied by replantation of the openings of the coronary arteries into the side according to the Benthall-De Bono technique...
2007: Angiologii︠a︡ i Sosudistai︠a︡ Khirurgii︠a︡, Angiology and Vascular Surgery
Elizabeth Braunlin, Shannon Mackey-Bojack, Angela Panoskaltsis-Mortari, James M Berry, Ron T McElmurry, Megan Riddle, Li-Yan Sun, Lorne A Clarke, Jakub Tolar, Bruce R Blazar
Hurler syndrome (mucopolysaccharidosis type I [MPS I]) is a uniformly lethal autosomal recessive storage disease caused by absence of the enzyme alpha-l-iduronidase (IDUA), which is involved in lysosomal degradation of sulfated glycosaminoglycans (GAGs). Cardiomyopathy and valvar insufficiency occur as GAGs accumulate in the myocardium, spongiosa of cardiac valves, and myointima of coronary arteries. Here we report the functional, biochemical, and morphologic cardiac findings in the MPS I mouse. We compare the cardiac functional and histopathological findings in the mouse to human MPS I...
January 2006: Pediatric Research
J C Levine, S P Sanders, S D Colan, R A Jonas, P J Spevak
Infants with coarctation of the aorta may have obstructions at other sites within the left heart which are not always apparent on the initial echocardiogram. The magnitude of the risk of having the additional obstructions is not well described, with few reliable quantitative criterions for identifying patients at the highest risk. We determined the frequency of additional, late appearing, stenotic lesions within the left heart, and the predictive morphologic features on the initial cross-sectional echocardiogram...
January 2001: Cardiology in the Young
J Turina, I Hippenmeyer-Zingg, M Schönbeck, M Turina
Severe aortic valve disease is a rare complication of coarctation in adults. Between 1961 and 1990 aortic valve replacement was performed after or combined with the operation of coarctation in 24 adults (4% of entire population operated for coarctation). Bicuspid aortic valves were present in 2/3 of patients. In 10 patients (7/10 with aortic stenosis) coarctation was operated early (mean age 24 years) and aortic valve late (mean age 40 years): in 14 (10/14 with aortic regurgitation, mean age 40 years) aortic valve and coarctation were operated simultaneously (8 patients) or staged within 6 months (6 patients)...
September 1997: Zeitschrift Für Kardiologie
V L Vetter
Sudden death in infants is rarely due to cardiac disease. Sudden death in children and adolescents is usually associated with cardiac disease. The major congenital lesions associated with sudden death are aortic stenosis, cardiomyopathies, idiopathic hypertrophic subaortic stenosis, Eisenmenger's syndrome, and cyanotic congenital defects with pulmonary stenosis or atresia. There is a high incidence of postoperative sudden death, especially associated with repair of tetralogy of Fallot and transposition of the great arteries...
1985: Cardiovascular Clinics
P M Shah, D L Roberts
The present review has attempted to summarize the classic symptoms and signs of aortic valve stenosis, especially in an adult. It is emphasized that all the classic signs rarely are present and their absence may mislead an unwary clinician. The diagnostic help provided by noninvasive tests, including echocardiography and phonocardiography, has been emphasized. A need for cardiac catheterization and angiography in most patients prior to corrective surgery is stressed. The natural history of the disease without operative intervention is dim and a significant risk of sudden death exists...
September 1977: Current Problems in Cardiology
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