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https://www.readbyqxmd.com/read/27343272/ovarian-hyperstimulation-syndrome-review-and-new-classification-criteria-for-reporting-in-clinical-trials
#1
P Humaidan, S M Nelson, P Devroey, C C Coddington, L B Schwartz, K Gordon, J L Frattarelli, B C Tarlatzis, H M Fatemi, P Lutjen, B J Stegmann
STUDY QUESTION: What is an objective approach that employs measurable and reproducible physiologic changes as the basis for the classification of ovarian hyperstimulation syndrome (OHSS) in order to facilitate more accurate reporting of incidence rates within and across clinical trials? SUMMARY ANSWER: The OHSS flow diagram is an objective approach that will facilitate consistent capture, classification and reporting of OHSS within and across clinical trials. WHAT IS KNOWN ALREADY: OHSS is a potentially life-threatening iatrogenic complication of the early luteal phase and/or early pregnancy after ovulation induction (OI) or ovarian stimulation (OS)...
September 2016: Human Reproduction
https://www.readbyqxmd.com/read/26307091/live-birth-rates-after-modified-natural-cycle-compared-with-high-dose-fsh-stimulation-using-gnrh-antagonists-in-poor-responders
#2
COMPARATIVE STUDY
Trifon G Lainas, Ioannis A Sfontouris, Christos A Venetis, George T Lainas, Ioannis Z Zorzovilis, Basil C Tarlatzis, Efstratios M Kolibianakis
STUDY QUESTION: Do live birth rates differ between modified natural cycles (MNCs) and cycles using high-dose follicle stimulating hormone (HDFSH) with gonadotrophin-releasing hormone (GnRH) antagonist in poor responder patients? SUMMARY ANSWER: Live birth rates are significantly higher in MNC compared with HDFSH GnRH antagonist cycles in poor responder patients. WHAT IS KNOWN ALREADY: Previous data on the efficiency of MNC in poor responders are very limited and suggest that MNC in vitro fertilization (IVF) does not offer a realistic solution for parenthood in these patients, since live birth rates are disappointingly low...
October 2015: Human Reproduction
https://www.readbyqxmd.com/read/26269538/androgen-levels-in-women-with-various-forms-of-ovarian-dysfunction-associations-with-cardiometabolic-features
#3
N M P Daan, L Jaspers, M P H Koster, F J M Broekmans, Y B de Rijke, O H Franco, J S E Laven, M Kavousi, B C J M Fauser
STUDY QUESTION: Are differences in androgen levels among women with various forms of ovarian dysfunction associated with cardiometabolic abnormalities? SUMMARY ANSWER: Androgen levels differed substantially between women with and without ovarian dysfunction, and increased androgen levels were associated with impaired cardiometabolic features in all women irrespective of their clinical condition. WHAT IS KNOWN ALREADY: Sex steroid hormones play important roles in the development of cardiovascular diseases (CVD)...
October 2015: Human Reproduction
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