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https://www.readbyqxmd.com/read/28429583/a-qualitative-study-of-the-role-of-australian-general-practitioners-in-the-surgical-management-of-obesity
#1
K Jose, A Venn, M Nelson, F Howes, S Wilkinson, D Ezzy
General practitioners (GPs) are increasingly managing patients with class 2 and 3 obesity (body mass index [BMI] > 35 and 40 kg/m(2) , respectively). Bariatric surgery is considered for patients with class 2 obesity and comorbidities or class 3 obesity where sustained weight loss using non-surgical interventions has not been achieved. In Australia, GPs facilitate access to surgery through referral processes, but the nature of GP involvement in bariatric pre- and post-surgery care is currently unclear...
April 20, 2017: Clinical Obesity
https://www.readbyqxmd.com/read/28429404/air-pollution-weight-loss-and-metabolic-benefits-of-bariatric-surgery-a-potential-model-for-study-of-metabolic-effects-of-environmental-exposures
#2
R Ghosh, W J Gauderman, H Minor, H A Youn, F Lurmann, K R Cromar, L Chatzi, B Belcher, C R Fielding, R McConnell
BACKGROUND: Emerging experimental evidence suggests that air pollution may contribute to development of obesity and diabetes, but studies of children are limited. OBJECTIVES: We hypothesized that pollution effects would be magnified after bariatric surgery for treatment of obesity, reducing benefits of surgery. METHODS: In 75 obese adolescents, excess weight loss (EWL), high-density lipoprotein (HDL) cholesterol, triglycerides, alkaline phosphatase (ALP) and hemoglobin A1c (HbA1c ) were measured prospectively at baseline and following laparoscopic adjustable gastric banding (LAGB)...
April 21, 2017: Pediatric Obesity
https://www.readbyqxmd.com/read/28420586/impaired-oral-absorption-of-methylphenidate-after-roux-en-y-gastric-bypass
#3
REVIEW
Carmil Azran, Peter Langguth, Arik Dahan
The anatomic and physiologic changes in the gastrointestinal (GI) tract after bariatric surgery may significantly affect the pharmacokinetics of medications taken by the patients for various reasons. Unfortunately, there is little information regarding changes in drug absorption after bariatric surgeries, limiting the ability of medical professionals to produce clear recommendations on what changes should be made to the formulations and dosing regimens of drugs after bariatric surgery. In this article, we report and analyze a case of 52-year-old male patient with morbid obesity and attention-deficit/hyperactivity disorder (ADHD) who experienced lack of methylphenidate efficacy after Roux en-Y gastric bypass (RYGB), which was eventually resolved by using the transdermal patch instead of an oral product...
March 9, 2017: Surgery for Obesity and related Diseases: Official Journal of the American Society for Bariatric Surgery
https://www.readbyqxmd.com/read/28409418/polymorphisms-in-cars-are-associated-with-gastric-cancer-risk-a-two-stage-case-control-study-in-the-chinese-population
#4
Tian Tian, Ling Xiao, Jiangbo Du, Xun Zhu, Yayun Gu, Na Qin, Caiwang Yan, Li Liu, Hongxia Ma, Yue Jiang, Jiaping Chen, Hao Yu, Juncheng Dai
BACKGROUND: The cysteinyl transfer RNA synthetase gene (CARS) is located on chromosome band 11p15.5, which is an important tumor-suppressor gene region. Mutations in CARS have been identified in many kinds of cancers; however, evidence for a relationship between genetic variants in CARS and gastric cancer at the population level is still lacking. Thus, we explored the association of variants in CARS with gastric cancer using a two-stage case-control strategy in Chinese. METHODS: We undertook a two-stage case-control study to investigate the association between polymorphisms in CARS and risk of gastric cancer with use of an Illumina Infinium(®) BeadChip and an ABI 7900 system...
April 13, 2017: Gastric Cancer
https://www.readbyqxmd.com/read/28405878/bariatric-surgery-and-endoluminal-procedures-ifso-worldwide-survey-2014
#5
L Angrisani, A Santonicola, P Iovino, A Vitiello, N Zundel, H Buchwald, N Scopinaro
BACKGROUND AND AIM: Several bariatric surgery worldwide surveys have been previously published to illustrate the evolution of bariatric surgery in the last decades. The aim of this survey is to report an updated overview of all bariatric procedures performed in 2014.For the first time, a special section on endoluminal techniques was added. METHODS: The 2014 International Federation for the Surgery of Obesity and Metabolic Disorders (IFSO) survey form evaluating the number and the type of surgical and endoluminal bariatric procedures was emailed to all IFSO societies...
April 13, 2017: Obesity Surgery
https://www.readbyqxmd.com/read/28395383/extending-magnifying-nbi-diagnosis-of-intestinal-metaplasia-in-the-stomach-the-white-opaque-substance-marker
#6
Takao Kanemitsu, Kenshi Yao, Takashi Nagahama, Kentaro Imamura, Shoko Fujiwara, Toshiharu Ueki, Kenta Chuman, Hiroshi Tanabe, Ota Atsuko, Akinori Iwashita, Toshio Shimokawa, Kunihisa Uchita, Takashi Kanesaka
Light-blue crests and white opaque substance are two features of intestinal metaplasia in the stomach that can be observed with magnifying narrow-band imaging. In a prospective pilot trial, Kanemitsu et al. show that combining these two findings significantly improves the sensitivity for detecting intestinal metaplasia. Background and aims Intestinal metaplasia (IM) of the stomach is associated with an increased risk of differentiated gastric cancer. While it is important to diagnose IM endoscopically, it can be difficult to observe by white-light endoscopy...
April 10, 2017: Endoscopy
https://www.readbyqxmd.com/read/28392935/measurement-of-hepatic-insulin-sensitivity-early-after-the-bypass-of-the-proximal-small-bowel-in-humans
#7
A D Miras, R Herring, A Vusirikala, F Shojaee-Moradi, N C Jackson, S Chandaria, S N Jackson, A P Goldstone, N Hakim, A G Patel, A M Umpleby, C W Le Roux
OBJECTIVE: Unlike gastric banding or sleeve gastrectomy procedures, intestinal bypass procedures, Roux-en-Y gastric bypass in particular, lead to rapid improvements in glycaemia early after surgery. The bypass of the proximal small bowel may have weight loss and even caloric restriction-independent glucose-lowering properties on hepatic insulin sensitivity. In this first human mechanistic study, we examined this hypothesis by investigating the early effects of the duodeno-jejunal bypass liner (DJBL; GI Dynamics, USA) on the hepatic insulin sensitivity by using the gold standard euglycaemic hyperinsulinaemic clamp methodology...
March 2017: Obesity Science & Practice
https://www.readbyqxmd.com/read/28392254/american-society-for-metabolic-and-bariatric-surgery-integrated-health-nutritional-guidelines-for-the-surgical-weight-loss-patient-2016-update-micronutrients
#8
Julie Parrott, Laura Frank, Rebecca Rabena, Lillian Craggs-Dino, Kellene A Isom, Laura Greiman
BACKGROUND: Optimizing postoperative patient outcomes and nutritional status begins preoperatively. Patients should be educated before and after weight loss surgery (WLS) on the expected nutrient deficiencies associated with alterations in physiology. Although surgery can exacerbate preexisting nutrient deficiencies, preoperative screening for vitamin deficiencies has not been the norm in the majority of WLS practices. Screening is important because it is common for patients who present for WLS to have at least 1 vitamin or mineral deficiency preoperatively...
January 19, 2017: Surgery for Obesity and related Diseases: Official Journal of the American Society for Bariatric Surgery
https://www.readbyqxmd.com/read/28386478/changes-in-the-microrna-profile-observed-in-the-subcutaneous-adipose-tissue-of-obese-patients-after-laparoscopic-adjustable-gastric-banding
#9
Carmela Nardelli, Laura Iaffaldano, Vincenzo Pilone, Giuseppe Labruna, Maddalena Ferrigno, Nicola Carlomagno, Concetta Anna Dodaro, Pietro Forestieri, Pasqualina Buono, Francesco Salvatore, Lucia Sacchetti
Background. Laparoscopic adjustable gastric banding (LAGB) results in significant lasting weight loss and improved metabolism in obese patients. To evaluate whether epigenetic factors could concur to these benefits, we investigated the subcutaneous adipose tissue (SAT) microRNA (miRNA) profile before (T0) and three years (T1) after LAGB in three morbidly obese women. Case Reports. SAT miRNA profiling, evaluated by TaqMan Array, showed four downexpressed (miR-519d, miR-299-5p, miR-212, and miR-671-3p) and two upexpressed (miR-370 and miR-487a) miRNAs at T1 versus T0...
2017: Journal of Obesity
https://www.readbyqxmd.com/read/28378195/characterization-of-ostertagia-ostertagi-annexin-like-proteins-at-different-developmental-stages
#10
Pooja Sharma, Mark Jenkins, Dante Zarlenga, Ray Fetterer, Zhengguo Xiao, Wenbin Tuo
Ostertagiosis remains an economically important parasitic disease in cattle in the temperate regions of the world. Repeated exposures to Ostertagia ostertagi in calves cause significant pathology in the abomasum but elicit little protective immunity. The larvae use the host's gastric glands as a niche for development, where the parasite completes its parasitic stages, while in the gastric glands, the larvae must down-regulate the host inflammatory immune responses. Annexin (ANX) A1, commonly found in most eukaryotes, is heavily involved in controlling anti-inflammatory responses by binding receptors on leukocytes...
March 29, 2017: Parasitology Research
https://www.readbyqxmd.com/read/28378086/the-bariatric-surgery-and-weight-losing-a-meta-analysis-in-the-long-and-very-long-term-effects-of-laparoscopic-adjustable-gastric-banding-laparoscopic-roux-en-y-gastric-bypass-and-laparoscopic-sleeve-gastrectomy-on-weight-loss-in-adults
#11
Mahdieh Golzarand, Karamollah Toolabi, Roya Farid
BACKGROUND: Several studies have been investigated to find the long-term effect of bariatric surgery on weight loss; nevertheless, a meta-analysis can detailedly demonstrate the effect of bariatric surgery on weight in morbidly obese patients. This study aimed to assess the long- and very long-term effects of laparoscopic adjustable gastric banding (LAGB), laparoscopic Roux-en-Y gastric bypass (LRYGB), and laparoscopic sleeve gastrectomy (LSG) on weight loss in adults. METHODS: An electronic search using PubMed, Scopus, and Google scholar databases was performed for all English-language articles up to May 15, 2016 with no publication date restriction...
April 4, 2017: Surgical Endoscopy
https://www.readbyqxmd.com/read/28376683/analyzing-the-effects-of-psychotherapy-on-weight-loss-after-laparoscopic-gastric-bypass-or-laparoscopic-adjustable-gastric-banding-in-patients-with-borderline-personality-disorder-a-prospective-study
#12
F Gallé, A Cirella, A M Salzano, V Di Onofrio, P Belfiore, G Liguori
BACKGROUND AND AIMS: Personality disorders are frequently associated with eating disorders in obese patients and may negatively affect weight loss and maintenance after bariatric surgery. This non-randomized study aimed to assess the effects of different psychotherapeutic interventions on weight loss in a sample of patients with borderline personality disorder who underwent laparoscopic gastric bypass or laparoscopic adjustable gastric banding. MATERIALS AND METHODS: A total of 153 bariatric patients meeting borderline personality disorder criteria were chosen voluntarily and consecutively to undergo an interpersonal individual treatment (n = 50), a dialectical behavioral group treatment (n = 50), or treatment as usual (n = 53) for a year after surgery...
April 1, 2017: Scandinavian Journal of Surgery: SJS
https://www.readbyqxmd.com/read/28366669/sexual-life-after-weight-loss-surgery
#13
Alexis Conason, Kimberly J McClure Brenchley, Andrea Pratt, Allan Geliebter
BACKGROUND: Previous research revealed a relationship between higher body mass index (BMI) and lower sexual functioning. However, the role of psychosocial variables, such as body image, in this relationship has been understudied. OBJECTIVE: To assess sexual life before and after weight loss surgery (WLS) and examine the role of body image and BMI in these changes. SETTING: WLS center at a major urban community hospital. METHODS: 327 participants (275 women and 52 men) who underwent either laparoscopic Roux-en-Y gastric bypass surgery (n = 225) or laparoscopic adjustable gastric band (n = 102) were assessed on measures of sexual life preoperatively and at 1, 3, 6, 12, and 24 months after surgery...
January 9, 2017: Surgery for Obesity and related Diseases: Official Journal of the American Society for Bariatric Surgery
https://www.readbyqxmd.com/read/28366441/narrow-band-imaging-versus-white-light-versus-mapping-biopsy-for-gastric-intestinal-metaplasia-a-prospective-blinded-trial
#14
James Buxbaum, David Hormozdi, Mário Dinis-Ribeiro, Christianne Lane, Diogo Dias da Silva, Ara Sahakian, Preeth Jayaram, Pedro Pimentel Nunes, Daniel Shue, Michael Pepper, Daniel Cho, Loren Laine
BACKGROUND & AIMS: Gastric intestinal metaplasia (GIM) is a gastric cancer precursor. Narrow-band imaging (NBI) may improve detection of GIM. We compared detection of GIM with high-definition white-light (HD-WL) endoscopy, NBI, and mapping biopsies in a population with increased gastric cancer risk. METHODS: Patients undergoing upper endoscopy had HD-WL examination by one endoscopist, followed by NBI examination by a second endoscopist blinded to HD-WL findings...
March 30, 2017: Gastrointestinal Endoscopy
https://www.readbyqxmd.com/read/28365914/the-physiology-and-pathophysiology-of-gastroesophageal-reflux-in-patients-with-laparoscopic-adjustable-gastric-band
#15
Richard Y Chen, Paul R Burton, Geraldine J Ooi, Cheryl Laurie, Andrew I Smith, Gary Crosthwaite, Paul E O'Brien, Geoff Hebbard, Peter D Nottle, Wendy A Brown
INTRODUCTION: The effect of the laparoscopic adjustable gastric band (LAGB) on esophageal acid exposure and reflux is poorly understood. Optimal technique and normative values for acid exposure have not been established in this group. METHODS: High-resolution manometry (HRM) and 24-h ambulatory esophageal pH monitoring were performed in three groups: asymptomatic LAGB, symptomatic LAGB, and pre-operative reflux patients. This technique utilized intraluminal pressure signatures during HRM to guide accurate pH sensor placement...
April 2, 2017: Obesity Surgery
https://www.readbyqxmd.com/read/28359101/treatment-of-pediatric-obesity-an-umbrella-systematic-review
#16
Tamim Rajjo, Khaled Mohammed, Mouaz Alsawas, Ahmed T Ahmed, Wigdan Farah, Noor Asi, Jehad Almasri, Larry J Prokop, Mohammad Hassan Murad
Objective: Multiple interventions are available to reduce excess body weight in children. We appraised the quality of evidence supporting each intervention and assessed the effectiveness on different obesity-related outcomes. Methods: We conducted a systematic search for systematic reviews of randomized controlled trials evaluating pediatric obesity interventions applied for ≥6 months. We assessed the quality of evidence for each intervention using GRADE (Grading of Recommendation, Assessment, Development, and Evaluation) approach...
March 1, 2017: Journal of Clinical Endocrinology and Metabolism
https://www.readbyqxmd.com/read/28347647/laparoscopic-sleeve-gastrectomy-after-failed-gastric-banding-is-it-really-effective-six-years-of-follow-up
#17
Sergio Carandina, Laurent Genser, Manuela Bossi, Claude Polliand, Malek Tabbara, Christophe Barrat
BACKGROUND: Laparoscopic sleeve gastrectomy (LSG) has become a valuable surgical option to rescue laparoscopic adjustable gastric banding (LAGB) failures. OBJECTIVES: The aim of this study was to determine whether conversion to LSG after failed LAGB (CLSG) is a well-tolerated and effective rescue procedure compared with primary LSG (PLSG) in the long term. SETTING: University hospital, France. METHODS: A retrospective review of data concerning consecutive patients receiving a LSG between February 2008 and December 2014 was conducted...
February 17, 2017: Surgery for Obesity and related Diseases: Official Journal of the American Society for Bariatric Surgery
https://www.readbyqxmd.com/read/28339024/effects-of-berberine-on-a-rat-model-of-chronic-stress-and-depression-via-gastrointestinal-tract-pathology-and-gastrointestinal-flora-profile-assays
#18
Xiaohui Zhu, Yangdong Sun, Chenggang Zhang, Haifeng Liu
Chronic stress and depression are challenging conditions to treat, owing to their complexity and lack of clinically available and effective therapeutic agents. The aim of the present study was to investigate the mechanism by which berberine acts, by examining alterations to gastrointestinal tract histopathology and flora profile in a rat model, following the induction of stress. Research associating gastrointestinal flora and depression has increased, thus, the present study hypothesized that stress induces depression and changes in the gastrointestinal system...
March 22, 2017: Molecular Medicine Reports
https://www.readbyqxmd.com/read/28337234/is-computerised-tomography-better-than-fibreoptic-gastroscopy-for-early-detection-of-gastric-varices
#19
Burak Suvak, Murat Kekilli, Yavuz Beyazıt, Sarper Okten, Alpaslan Tanoglu, Nurgul Sasmaz
INTRODUCTION: Video endoscopic diagnosis of gastric varices is particularly limited, owing to the deep submucosal or subserosal location of the varices and the normal appearance of the overlying mucosa. AIM: We present and emphasise the value of computerised tomography (CT) examination in the early detection of gastric varices (GVs). MATERIAL AND METHODS: In this retrospective study, a total of 216 consecutive patients with cirrhosis were evaluated at the Turkiye Yuksek Ihtisas Training and Research Hospital between September 2008 and March 2011...
2017: Przegla̜d Gastroenterologiczny
https://www.readbyqxmd.com/read/28335099/endoscopic-treatment-of-diverse-complications-caused-by-laparoscopic-adjustable-gastric-banding-a-study-in-eastern-asia
#20
Su Young Kim, Kyong Yong Oh, Jun-Won Chung, Yoon Jae Kim, Kyoung Oh Kim, Kwang An Kwon, Dong Kyun Park, Kyoung Kon Kim, Seong Min Kim
Background/Aims: The use of laparoscopic adjustable gastric banding (LAGB) is increasing proportionally with the obesity epidemic. However, some postoperative complications have been highlighted as major problems associated with LAGB. There is no consensus concerning the endoscopic management of these adverse events. The aim of this study was to retrospectively review the feasibility and effectiveness of endoscopic treatment for LAGB complications. Methods: We retrospectively evaluated 352 patients who underwent LAGB between 2011 and 2015...
March 24, 2017: Gut and Liver
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