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https://www.readbyqxmd.com/read/28811019/introducing-a-new-and-rapid-microextraction-approach-based-on-magnetic-ionic-liquids-stir-bar-dispersive-liquid-microextraction
#1
Alberto Chisvert, Juan L Benedé, Jared L Anderson, Stephen A Pierson, Amparo Salvador
With the aim of contributing to the development and improvement of microextraction techniques, a novel approach combining the principles and advantages of stir bar sorptive extraction (SBSE) and dispersive liquid-liquid microextraction (DLLME) is presented. This new approach, termed stir bar dispersive liquid microextraction (SBDLME), involves the addition of a magnetic ionic liquid (MIL) and a neodymium-core magnetic stir bar into the sample allowing the MIL coat the stir bar due to physical forces (i.e., magnetism)...
August 29, 2017: Analytica Chimica Acta
https://www.readbyqxmd.com/read/28810562/anti-depressant-like-effects-of-jieyu-chufan-capsules-in-a-mouse-model-of-unpredictable-chronic-mild-stress
#2
Hui Zhao, Bingyu Liang, Linjie Yu, Yun Xu
Jieyu chufan (JYCF) is a well-known Chinese traditional medicine used for depression; however, the molecular mechanism underlying its anti-depressant action has remained elusive. In the present study, the anti-depressant effects of JYCF and the potential mechanisms were investigated in a mouse model. Five groups of 12 C57BL/6 mice each were used in the study, including a normal control group (NC group), a model control group (MC group) and three groups, which received different doses of JYCF (1.25, 2.5 and 5 g/kg) orally for 21 days (JYCF groups)...
August 2017: Experimental and Therapeutic Medicine
https://www.readbyqxmd.com/read/28774617/monitoring-and-factors-affecting-levels-of-airborne-and-water-bromoform-in-chlorinated-seawater-swimming-pools
#3
Jean-Luc Boudenne, Julien Parinet, Carine Demelas, Tarek Manasfi, Bruno Coulomb
Water and air quality of eight seawater swimming pools using chlorine disinfection was measured during four sampling campaigns, spread on one full-year, and in four thalassotherapy centers located in Southeast of France. Concentrations of trihalomethanes (THMs) in air and in water as well as concentrations of parameters, including nonpurgeable organic carbon (NPOC), free residual chlorine (Clf), pH, Kjeldhal Nitrogen (KN), salinity, conductivity, bromide ions and, water and air temperature, were measured. Water and air samples were collected in triplicates morning - at the opening of the pools -, noon and night - at the closing of the pools -, in summer and winter...
August 2017: Journal of Environmental Sciences (China)
https://www.readbyqxmd.com/read/28756389/sports-injury-and-illness-incidence-in-the-rio-de-janeiro-2016-olympic-summer-games-a-prospective-study-of-11-274-athletes-from-207-countries
#4
Torbjørn Soligard, Kathrin Steffen, Debbie Palmer, Juan Manuel Alonso, Roald Bahr, Alexandre Dias Lopes, Jiri Dvorak, Marie-Elaine Grant, Willem Meeuwisse, Margo Mountjoy, Leonardo Oliveira Pena Costa, Natalia Salmina, Richard Budgett, Lars Engebretsen
OBJECTIVE: To describe the pattern of injuries and illnesses sustained during the Games of the XXXI Olympiad, hosted by Rio de Janeiro from 5 to 21 August 2016. METHODS: We recorded the daily incidence of athlete injuries and illnesses (1) through the reporting of all National Olympic Committee (NOC) medical teams and (2) in the polyclinic and medical venues by the Rio 2016 medical staff. RESULTS: In total, 11 274 athletes (5089 women, 45%; 6185 men, 55%) from 207 NOCs participated in the study...
July 29, 2017: British Journal of Sports Medicine
https://www.readbyqxmd.com/read/28745642/assessing-spatial-memory-impairment-in-a-mouse-model-of-traumatic-brain-injury-using-a-radial-water-tread-maze
#5
Marcella M Cline, Megan A Ostlie, Chloe G Cross, Gregory G Garwin, Satoshi Minoshima, Donna J Cross
Despite the recent increase in use of mouse models in scientific research, researchers continue to use cognitive tasks that were originally designed and validated for rat use. The Radial Water Tread (RWT) maze test of spatial memory (designed specifically for mice and requiring no swimming) has been shown previously to successfully distinguish between controlled cortical impact-induced TBI mice and sham controls. Here, a detailed protocol for this task is presented. The RWT maze capitalizes on the natural tendency of mice to avoid open areas in favor of hugging the sides of an apparatus (thigmotaxis)...
July 17, 2017: Journal of Visualized Experiments: JoVE
https://www.readbyqxmd.com/read/28662189/affective-and-cognitive-behavior-in-the-alpha-galactosidase-a-deficient-mouse-model-of-fabry-disease
#6
Lukas Hofmann, Franziska Karl, Claudia Sommer, Nurcan Üçeyler
Fabry disease is an X-linked inherited lysosomal storage disorder with intracellular accumulation of globotriaosylceramide (Gb3) due to α-galactosidase A (α-Gal A) deficiency. Fabry patients frequently report of anxiety, depression, and impaired cognitive function. We characterized affective and cognitive phenotype of male mice with α-Gal A deficiency (Fabry KO) and compared results with those of age-matched male wildtype (WT) littermates. Young (3 months) and old (≥ 18 months) mice were tested in the naïve state and after i...
2017: PloS One
https://www.readbyqxmd.com/read/28655697/banana-fruit-pulp-and-peel-involved-in-antianxiety-and-antidepressant-effects-while-invigorate-memory-performance-in-male-mice-possible-role-of-potential-antioxidants
#7
Noreen Samad, Aqsa Muneer, Najeeb Ullah, Aqal Zaman, M Mazhar Ayaz, Ijaz Ahmad
The present study was aimed to investigate the anti-stress and memory enhancing effects of banana (Musa sapientum L.) fruit pulp and peel extract in male mice. Locally bred albino Wistar mice were divided into control and 2 test groups (n=10). Control rats received drinking water while test groups were treated with banana fruit pulp (600 mg/kg; oral administration) and extract of banana peel (400mg/kg; oral administration). Behavioral activities of animals were monitored 14 days post administration of banana pulp and peel extract...
May 2017: Pakistan Journal of Pharmaceutical Sciences
https://www.readbyqxmd.com/read/28637659/enduring-effects-of-perinatal-nicotine-exposure-on-murine-sleep-in-adulthood
#8
Jeremy Charles Borniger, Reuben F Don, Ning Zhang, Robert Thomas Boyd, Randy J Nelson
The long-term consequences of early life nicotine exposure are poorly defined. Approximately 8-10% of women report smoking during pregnancy, and this may promote aberrant development in the offspring. To this end, we investigated potential enduring effects of perinatal nicotine exposure on murine sleep and affective behaviors in adulthood (~13-15 weeks of age) in C57Bl6j mice. Mothers received a water bottle containing 200 µg/ml nicotine bitartrate dihydrate in 2% w/v saccharin or pH-matched 2% saccharin with 0...
June 21, 2017: American Journal of Physiology. Regulatory, Integrative and Comparative Physiology
https://www.readbyqxmd.com/read/28632299/simningsorsakat-lung%C3%A3-dem-vid-svenska-f%C3%A3-rh%C3%A3-llanden-otillr%C3%A3-ckligt-studerat-erfarenheter-fr%C3%A3-n-vansbrosimningen-2016
#9
Annika Braman Eriksson, Martin Annsberg, Maria Hårdstedt
Swimming-induced pulmonary edema (SIPE) has been described in sports and military medicine during strenuous swimming in open water. Symptoms include dyspnea, cough, frothy mucus and hemoptysis. Hypertension, a tight wetsuit, overhydration and previous episodes of SIPE are suggested risk factors. Immediate interruption of swimming prevents more serious symptoms. In the open water race at Vansbro 2016, 69 swimmers (of 13,878 in total) were treated for symptoms suspected for SIPE. Continuous positive airway pressure (CPAP) was successfully used to treat suspected SIPE in 46 patients in the on-site emergency care center...
June 20, 2017: Läkartidningen
https://www.readbyqxmd.com/read/28620151/reproductive-innovation-and-the-recognition-of-a-new-genus-within-the-polystomatidae-monogenea-infecting-chelonian-vertebrates
#10
Richard C Tinsley
Polystomatid monogeneans have a wide diversity of life cycles correlated with the varied ecology and behaviour of their aquatic vertebrate hosts. Typically, transmission involves a swimming infective larva but most hosts are amphibious and invasion is interrupted when hosts leave water. A key life cycle adaptation involves a uterus that, in the most specialised cases, may contain several hundred fully-developed larvae prepared for instant host-to-host transmission. By contrast, one subfamily of the Polystomatidae - the Polystomoidinae, specific to chelonians (freshwater turtles) - has a simplified reproductive system without a uterus...
June 7, 2017: Folia Parasitologica
https://www.readbyqxmd.com/read/28566681/dimethyl-sulfide-is-a-chemical-attractant-for-reef-fish-larvae
#11
Matthew A Foretich, Claire B Paris, Martin Grosell, John D Stieglitz, Daniel D Benetti
Transport of coral reef fish larvae is driven by advection in ocean currents and larval swimming. However, for swimming to be advantageous, larvae must use external stimuli as guides. One potential stimulus is "odor" emanating from settlement sites (e.g., coral reefs), signaling the upstream location of desirable settlement habitat. However, specific chemicals used by fish larvae have not been identified. Dimethyl sulfide (DMS) is produced in large quantities at coral reefs and may be important in larval orientation...
May 31, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28533550/coral-larvae-are-poor-swimmers-and-require-fine-scale-reef-structure-to-settle
#12
Tom Hata, Joshua S Madin, Vivian R Cumbo, Mark Denny, Joanna Figueiredo, Saki Harii, Christopher J Thomas, Andrew H Baird
Reef coral assemblages are highly dynamic and subject to repeated disturbances, which are predicted to increase in response to climate change. Consequently there is an urgent need to improve our understanding of the mechanisms underlying different recovery scenarios. Recent work has demonstrated that reef structural complexity can facilitate coral recovery, but the mechanism remains unclear. Similarly, experiments suggest that coral larvae can distinguish between the water from healthy and degraded reefs, however, whether or not they can use these cues to navigate to healthy reefs is an open question...
May 22, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28490880/protective-efficacy-of-a-single-salvianolic-acid-a-treatment-on-photothrombosis-induced-sustained-spatial-memory-impairments
#13
Chun-Xiang Jiao, Heng Zhou, Chun-Xian Yang, Chen Ma, Yue-Xiong Yang, Rong-Rong Mao, Lin Xu, Qi-Xin Zhou
With respect to the high burden of ischemic stroke and the absence of pharmacological treatment for promoting rehabilitation, promising candidates with specific effects on long-term functional recovery are highly desired. Candidates need reasonable experimental paradigms to evaluate the long-term functional outcome focused on ischemia-induced sensorimotor and memory deficits. "Danshen", a traditional Chinese herb, has long been used to treat coronary and cerebral vascular diseases as well as dementia. Salvianolic acid A (SAA), one of the major active ingredients of Danshen, was demonstrated to be effective in protecting against cerebral ischemic injury...
2017: Neuropsychiatric Disease and Treatment
https://www.readbyqxmd.com/read/28489717/coliphages-and-gastrointestinal-illness-in-recreational-waters-pooled-analysis-of-six-coastal-beach-cohorts
#14
Jade Benjamin-Chung, Benjamin F Arnold, Timothy J Wade, Kenneth Schiff, John F Griffith, Alfred P Dufour, Stephen B Weisberg, John M Colford
BACKGROUND: Coliphages have been proposed as indicators of fecal contamination in recreational waters because they better mimic the persistence of pathogenic viruses in the environment and wastewater treatment than fecal indicator bacteria. We estimated the association between coliphages and gastrointestinal illness and compared it with the association with culturable enterococci. METHODS: We pooled data from six prospective cohort studies that enrolled coastal beachgoers in California, Alabama, and Rhode Island...
September 2017: Epidemiology
https://www.readbyqxmd.com/read/28459347/characteristics-and-challenges-of-open-water-swimming-performance-a-review
#15
Roberto Baldassarre, Marco Bonifazi, Paola Zamparo, Maria Francesca Piacentini
PURPOSE: Although the popularity of open water swimming (OWS) events has significantly increased in the last decades, specific studies regarding performance of elite or age group athletes in these events are scarce. The purpose of this review is to analyse the existing literature on OWS. METHODS: Relevant literature was located via computer-generated citations: during August 2016, online computer searches on PubMed and Scopus databases were conducted to locate published research...
May 1, 2017: International Journal of Sports Physiology and Performance
https://www.readbyqxmd.com/read/28424217/use-of-life-jackets-and-other-types-of-flotation-for-in-water-recreation-in-designated-swim-areas-in-washington-state
#16
Linda Quan, Thomas Mangione, Elizabeth Bennett, Wendy Chow
Most fatal drownings worldwide occur in open water. Flotation devices may protect swimmers. Their use by those recreating in water has not been described. METHODS: Observational survey of swimmers and waders at designated swim sites at lakes and rivers evaluated them by age group, sex, type of flotation used (life jacket vs substandard flotation, eg, water wings, noodles, inflatables) and, for children <6 years, being within arm's reach of an adult. RESULTS: Of 1967 swimmers/waders observed, 37% used some type of flotation device...
April 19, 2017: Injury Prevention: Journal of the International Society for Child and Adolescent Injury Prevention
https://www.readbyqxmd.com/read/28410356/water-exposure-is-a-common-risk-behavior-among-soft-and-gas-permeable-contact-lens-wearers
#17
Aaron B Zimmerman, Kathryn Richdale, Gladys Lynn Mitchell, Beth T Kinoshita, Dawn Y Lam, Heidi Wagner, Luigina Sorbara, Robin L Chalmers, Sarah A Collier, Jennifer R Cope, Maya M Rao, Michael J Beach, Jonathan S Yoder
PURPOSE: To understand soft contact lens (SCL) and gas-permeable (GP) lens wearers' behaviors and knowledge regarding exposure of lenses to water. METHODS: The Contact Lens Risk Survey (CLRS) and health behavior questions were completed online by a convenience sample of 1056 SCL and 85 GP lens wearers aged 20 to 76 years. Participants were asked about exposing their lenses to water and their understanding of risks associated with these behaviors. Chi-square analyses examined relationships between patient behaviors and perceptions...
August 2017: Cornea
https://www.readbyqxmd.com/read/28392460/mesoporous-hydroxyapatite-as-a-carrier-of-olanzapine-for-long-acting-antidepression-treatment-in-rats-with-induced-depression
#18
Yan-Jye Shyong, Mao-Hsien Wang, Li-Wei Kuo, Chang-Fu Su, Wei-Ting Kuo, Kuo-Chi Chang, Feng-Huei Lin
An antidepressant carrier, mesoporous hydroxyapatite olanzapine (mesoHAP-OLZ), was designed to maintain 3weeks of constant medication release. The carrier was intramuscularly (IM) injected, where cellular activity played a role in achieving the goal of constant release. The efficiency of the treatment was evaluated from 3 perspectives in in vivo studies: locomotor activities, biomarkers, and learning and memory ability. MesoHAP-OLZ can increase the locomotor activity in rats with induced depression determined by open field test (OFT) and forced swim test (FST)...
April 6, 2017: Journal of Controlled Release: Official Journal of the Controlled Release Society
https://www.readbyqxmd.com/read/28390940/ginkgo-biloba-l-attenuates-spontaneous-recurrent-seizures-and-associated-neurological-conditions-in-lithium-pilocarpine-rat-model-of-temporal-lobe-epilepsy-through-inhibition-of-mammalian-target-of-rapamycin-pathway-hyperactivation
#19
Arindam Ghosh Mazumder, Pallavi Sharma, Vikram Patial, Damanpreet Singh
ETHNOPHARMACOLOGICAL RELEVANCE: Ginkgo biloba L. (Ginkgoaceae) has been widely used in traditional medicine for variety of neurological conditions particularly behavioral and memory impairments. AIM OF THE STUDY: The present study was envisaged to explore the effect of a standardized fraction of Ginkgo biloba leaves (GBbf) in rat model of lithium-pilocarpine induced spontaneous recurrent seizures, and associated behavioral impairments and cognitive deficit. MATERIALS AND METHODS: Rats showing appearance of spontaneous recurrent seizures following lithium pilocarpine (LiPc)-induced status epilepticus (SE) were treated with different doses of GBbf or vehicle for subsequent 4 weeks...
May 23, 2017: Journal of Ethnopharmacology
https://www.readbyqxmd.com/read/28380075/repeated-brief-isoflurane-anesthesia-during-early-postnatal-development-produces-negligible-changes-on-adult-behavior-in-male-mice
#20
Marko Rosenholm, Emmi Paro, Hanna Antila, Vootele Võikar, Tomi Rantamäki
Brain development is a complex process regulated by genetic programs and activity-dependent neuronal connectivity. Anesthetics profoundly alter neuronal excitability, and anesthesia during early brain development has been consistently associated with neuroapoptosis, altered synaptogenesis, and persistent behavioral abnormalities in experimental animals. However, the depth, and even more the duration and developmental time point(s) of exposure to anesthesia determine the neuropathological and long-term behavioral consequences of anesthetics...
2017: PloS One
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