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https://www.readbyqxmd.com/read/29773076/risk-factors-for-schistosomiasis-in-an-urban-area-in-northern-c%C3%A3-te-d-ivoire
#1
Richard K M'Bra, Brama Kone, Yapi G Yapi, Kigbafori D Silué, Ibrahima Sy, Danielle Vienneau, Nagnin Soro, Guéladio Cissé, Jürg Utzinger
BACKGROUND: Schistosomiasis is a water-based disease transmitted by trematodes belonging to the genus Schistosoma. The aim of this study was to assess the relationship between the prevalence of schistosomiasis and access to water, sanitation and hygiene (WASH) and environmental and socioeconomic factors in the city of Korhogo, northern Côte d'Ivoire. METHODS: A cross-sectional study including 728 randomly selected households was conducted in Korhogo in March 2015...
May 18, 2018: Infectious Diseases of Poverty
https://www.readbyqxmd.com/read/29743492/mesoscale-eddies-influence-the-movements-of-mature-female-white-sharks-in-the-gulf-stream-and-sargasso-sea
#2
Peter Gaube, Camrin D Braun, Gareth L Lawson, Dennis J McGillicuddy, Alice Della Penna, Gregory B Skomal, Chris Fischer, Simon R Thorrold
Satellite-tracking of mature white sharks (Carcharodon carcharias) has revealed open-ocean movements spanning months and covering tens of thousands of kilometers. But how are the energetic demands of these active apex predators met as they leave coastal areas with relatively high prey abundance to swim across the open ocean through waters often characterized as biological deserts? Here we investigate mesoscale oceanographic variability encountered by two white sharks as they moved through the Gulf Stream region and Sargasso Sea in the North Atlantic Ocean...
May 9, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29735445/-effect-of-intrahippocampal-injection-of-anti-cellular-prion-protein-monoclonal-antibody-on-cognitive-deficits-in-appswe-psen1-de9-transgenic-mice
#3
Hai-Ying Zhang, Yi-Heng Liu, Yuan Fu, Peng-Cheng Chen, Rui Lu, Jian-Xing Li, Ming-Hui Chen, Hao-Chi Yang, Yu-Sheng Zhang
OBJECTIVE: To study the effects of intrahippocampal injection of cellular prion protein (PrPC ) antibody on cognitive deficits of APPswe/PSEN1dE9 transgenic mice. METHODS: Eight-month-old male APPswe/PSEN1dE9 transgenic mice were subjected to bilateral intrahippocampal injection of a single dose (2 µL) of anti-PrPC monoclonal antibody (EP1802Y) or PBS, with wild-type C57Bl/6J mice serving as the control group. After two months, the mice were tested for cognitive behaviors using open filed (OF) test, Morris water maze (MWM) test, fear conditioning (FC) test, and novel object recognition (NOR) test, and immunohistochemistry was used to examine the changes in hippocampal expression of Aβ1-42 ...
April 20, 2018: Nan Fang Yi Ke da Xue Xue Bao, Journal of Southern Medical University
https://www.readbyqxmd.com/read/29735436/-nicorandil-improves-cognitive-dysfunction-in-mice-with-streptozotocin-induced-diabetes
#4
Wen-Hui Yan, Chun-Xi Zhang, Tong Xing, Xue Gong, Yu-Xuan Yang, Yi-Nuo Li, Xuan Liu, Jiamaliding Ayijiang, Ye Yu, Meng Zhang, Li-Na Chen
OBJECTIVE: To observe the protective effects of potassium channel opener nicorandil against cognitive dysfunction in mice with streptozotocin (STZ)-induced diabetes. METHODS: C57BL/6J mouse models of type 1 diabetes mellitus (T1DM) were established by intraperitoneal injection of STZ and received daily treatment with intragastric administration of nicorandil or saline (model group) for 4 consecutive weeks, with normal C57BL/6J mice serving as control. Fasting blood glucose level was recorded every week and Morris water maze was used to evaluate the cognitive behavior of the mice in the 4th week...
April 20, 2018: Nan Fang Yi Ke da Xue Xue Bao, Journal of Southern Medical University
https://www.readbyqxmd.com/read/29611260/non-continuous-super-diffusive-dynamics-of-light-activated-nanobottle-motor
#5
Mingjun Xuan, Rafael Mestre, Changyong Gao, Chang Zhou, Qiang He, Samuel Sanchez
We report a carbonaceous nanobottle (CNB) motor for near infrared (NIR) light-driven jet propulsion. The bottle structure of the CNB motor is fabricated by soft-template-based polymerization. Upon illumination with NIR light, the photothermal effect of the CNB motor carbon shell causes a rapid increase in the temperature of the interior water and thus the ejection of the heated fluid from the open neck, which propels the CNB motor. The occurrence of an explosion, the "on/off" motion, and the swing behavior of the CNB motor can be modulated by adjusting the NIR light source...
April 3, 2018: Angewandte Chemie
https://www.readbyqxmd.com/read/29508650/sex-difference-in-long-distance-open-water-swimming-races-does-nationality-play-a-role
#6
Pantelis T Nikolaidis, Caio V de Sousa, Beat Knechtle
In open-water swimming events with non-elite swimmers held in the USA, but not in Europe, women were faster than men. We examined the sex difference in elite long-distance open-water swimming races and the role of nationality by investigating 7,468 swimmers competing in 5 km, 10 km and 25 km FINA races held between 2000 and 2016. More men participated in 10 km and 25 km than in 5km races. Men were faster than women and the sex difference was similar in all race distances. Swimming speed was faster for 5km than for 10km, which in turn was faster than 25km...
March 6, 2018: Research in Sports Medicine
https://www.readbyqxmd.com/read/29503588/the-relationship-of-wearing-a-wetsuit-in-long-distance-open-water-swimming-with-sex-age-calendar-year-performance-and-nationality-crossing-the-strait-of-gibraltar
#7
Pantelis Theodoros Nikolaidis, Caio Victor Sousa, Beat Knechtle
Aim: The aim of the present study was to investigate the relationship of wearing a wetsuit with sex, age group, nationality, calendar year, and performance in crossing the "Strait of Gibraltar"(14.3 km). Materials and methods: A sample of 1,130 open-water (females, n=180, age 35.9±11.9 years; males, n=950, age 40.0±10.2 years) ultra-distance swimmers crossing the "Strait of Gibraltar" since 1950 was analyzed. Results: Male, older, and Spanish swimmers used wetsuits more often than female, younger, and athletes of other nationalities, respectively, and the use of the wetsuit has increased during the past three decades...
2018: Open Access Journal of Sports Medicine
https://www.readbyqxmd.com/read/29489846/habitat-selection-and-seasonal-movements-of-young-bearded-seals-erignathus-barbatus-in-the-bering-sea
#8
Michael F Cameron, Kathryn J Frost, Jay M Ver Hoef, Greg A Breed, Alex V Whiting, John Goodwin, Peter L Boveng
The first year of life is typically the most critical to a pinniped's survival, especially for Arctic phocids which are weaned at only a few weeks of age and left to locate and capture prey on their own. Their seasonal movements and habitat selection are therefore important factors in their survival. During a cooperative effort between scientists and subsistence hunters in October 2004, 2005, and 2006, 13 female and 13 male young (i.e., age <2) bearded seals (Erignathus barbatus) were tagged with satellite-linked dive recorders (SDRs) in Kotzebue Sound, Alaska...
2018: PloS One
https://www.readbyqxmd.com/read/29487154/kinematics-of-swimming-of-the-manta-ray-three-dimensional-analysis-of-open-water-maneuverability
#9
Frank E Fish, Allison Kolpas, Andrew Crossett, Michael A Dudas, Keith W Moored, Hilary Bart-Smith
For aquatic animals, turning maneuvers represent a locomotor activity that may not be confined to a single coordinate plane, making analysis difficult, particularly in the field. To measure turning performance in a three-dimensional space for the manta ray ( Mobula birostris ), a large open-water swimmer, scaled stereo video recordings were collected. Movements of the cephalic lobes, eye and tail base were tracked to obtain three-dimensional coordinates. A mathematical analysis was performed on the coordinate data to calculate the turning rate and curvature (1/turning radius) as a function of time by numerically estimating the derivative of manta trajectories through three-dimensional space...
March 22, 2018: Journal of Experimental Biology
https://www.readbyqxmd.com/read/29485642/modulatory-role-of-rutin-supplement-on-open-space-forced-swim-test-murine-model-of-depression
#10
Y Yusha'u, U A Muhammad, M Nze, J M Egwuma, O J Igomu, M Abdulkadir
Flavonoids have been demonstrated to possess an anti-depressant effect and less adverse effects than tricyclic anti-depressants. For this reason, flavonoids in natural products have attracted growing attention. Rutin is a glycoside flavonoid which belongs to an important class of flavonoids, abundantly found in plants, such as buckwheat seeds, asparagus, red pepper, apples, citrus fruits and leaves of many herbs such as rosemary, dandelion or sage, and black and green tea.  It is a vital nutritional component of food stuff...
December 30, 2017: Nigerian Journal of Physiological Sciences: Official Publication of the Physiological Society of Nigeria
https://www.readbyqxmd.com/read/29483242/convergence-of-marine-megafauna-movement-patterns-in-coastal-and-open-oceans
#11
A M M Sequeira, J P Rodríguez, V M Eguíluz, R Harcourt, M Hindell, D W Sims, C M Duarte, D P Costa, J Fernández-Gracia, L C Ferreira, G C Hays, M R Heupel, M G Meekan, A Aven, F Bailleul, A M M Baylis, M L Berumen, C D Braun, J Burns, M J Caley, R Campbell, R H Carmichael, E Clua, L D Einoder, Ari Friedlaender, M E Goebel, S D Goldsworthy, C Guinet, J Gunn, D Hamer, N Hammerschlag, M Hammill, L A Hückstädt, N E Humphries, M-A Lea, A Lowther, A Mackay, E McHuron, J McKenzie, L McLeay, C R McMahon, K Mengersen, M M C Muelbert, A M Pagano, B Page, N Queiroz, P W Robinson, S A Shaffer, M Shivji, G B Skomal, S R Thorrold, S Villegas-Amtmann, M Weise, R Wells, B Wetherbee, A Wiebkin, B Wienecke, M Thums
The extent of increasing anthropogenic impacts on large marine vertebrates partly depends on the animals' movement patterns. Effective conservation requires identification of the key drivers of movement including intrinsic properties and extrinsic constraints associated with the dynamic nature of the environments the animals inhabit. However, the relative importance of intrinsic versus extrinsic factors remains elusive. We analyze a global dataset of ∼2.8 million locations from >2,600 tracked individuals across 50 marine vertebrates evolutionarily separated by millions of years and using different locomotion modes (fly, swim, walk/paddle)...
March 20, 2018: Proceedings of the National Academy of Sciences of the United States of America
https://www.readbyqxmd.com/read/29444592/antidepressant-like-effects-of-vaccinium-bracteatum-in-chronic-restraint-stress-mice-functional-actions-and-mechanism-explorations
#12
Dool-Ri Oh, Yujin Kim, Eun-Jin Choi, Myung-A Jung, Kyo-Nyeo Oh, Ji-Ae Hong, Donghyuck Bae, Kwangsu Kim, Huwon Kang, Jaeyong Kim, Young Ran Kim, Seung Sik Cho, Chul-Young Choi
The fruit of Vaccinium bracteatum Thunb. (VBF) is commonly known as the oriental blueberry in Korea. The aim of this study was to evaluate the antidepressant-like effects of water VBF extract (VBFW) in a mouse model of chronic restraint stress (CRS) and to identify the underlying mechanisms of its action. The behavioral effects of VBFW were assessed in the forced swim test (FST) and open field test (OFT). The levels of serum corticosterone (CORT), brain monoamines, in addition to the extracellular signal-regulated kinases (ERKs)/protein kinase B (Akt) signaling pathway were evaluated...
2018: American Journal of Chinese Medicine
https://www.readbyqxmd.com/read/29440051/cold-forced-open-water-swimming-a-natural-intervention-to-improve-postoperative-pain-and-mobilisation-outcomes
#13
Tom B Mole, Pieter Mackeith
Postoperative neuropathic pain exacerbated by movement is poorly understood and difficult to treat but a relatively common complication of surgical procedures such as endoscopic thoracic sympathectomy. Here, we describe a case of unexpected, immediate, complete and sustained remission of postoperative intercostal neuralgia after the patient engaged in an open-water swim in markedly cold conditions. Though an incidental chance association is possible, the clear temporal proximity linking the swim with pain remission makes a causal relationship possible...
February 12, 2018: BMJ Case Reports
https://www.readbyqxmd.com/read/29382344/age-related-cognitive-impairment-is-associated-with-long-term-neuroinflammation-and-oxidative-stress-in-a-mouse-model-of-episodic-systemic-inflammation
#14
Joana Costa d'Avila, Luciana Domett Siqueira, Aurélien Mazeraud, Estefania Pereira Azevedo, Debora Foguel, Hugo Caire Castro-Faria-Neto, Tarek Sharshar, Fabrice Chrétien, Fernando Augusto Bozza
BACKGROUND: Microglia function is essential to maintain the brain homeostasis. Evidence shows that aged microglia are primed and show exaggerated response to acute inflammatory challenge. Systemic inflammation signals to the brain inducing changes that impact cognitive function. However, the mechanisms involved in age-related cognitive decline associated to episodic systemic inflammation are not completely understood. The aim of this study was to identify neuropathological features associated to age-related cognitive decline in a mouse model of episodic systemic inflammation...
January 30, 2018: Journal of Neuroinflammation
https://www.readbyqxmd.com/read/29381420/euhaplorchis-californiensis-cercariae-exhibit-positive-phototaxis-and-negative-geotaxis
#15
Kelly Lynne Weinersmith, Caroline E Brown, Kira B Clingen, Marie C Jacobsen, Leah B Topper, Ryan F Hechinger
Parasites often use external cues to identify and move toward environments where they are likely to encounter suitable hosts. The trematode parasite Euhaplorchis californiensis produces cercariae that emerge from California horn snails (Cerithideopsis californica (=Cerithidea californica)) to infect California killifish (Fundulus parvipinnis) as second intermediate hosts. Based on work on a congeneric Euhaplorchis species from Florida, and based on the ecology of its killifish host, we hypothesized that E. californiensis cercariae in southern California estuaries are positively phototactic and negatively geotactic, using both sunlight and gravity to guide their movement to the upper water column...
February 27, 2018: Journal of Parasitology
https://www.readbyqxmd.com/read/29379877/long-term-visual-training-increases-visual-acuity-and-long-term-monocular-deprivation-promotes-ocular-dominance-plasticity-in-adult-standard-cage-raised-mice
#16
Leon Hosang, Rashad Yusifov, Siegrid Löwel
For routine behavioral tasks, mice predominantly rely on olfactory cues and tactile information. In contrast, their visual capabilities appear rather restricted, raising the question whether they can improve if vision gets more behaviorally relevant. We therefore performed long-term training using the visual water task (VWT): adult standard cage (SC)-raised mice were trained to swim toward a rewarded grating stimulus so that using visual information avoided excessive swimming toward nonrewarded stimuli. Indeed, and in contrast to old mice raised in a generally enriched environment (Greifzu et al...
January 2018: ENeuro
https://www.readbyqxmd.com/read/29355696/effects-of-non-purified-and-semi-purified-commercial-diets-on-behaviors-plasma-corticosterone-levels-and-cecum-microbiome-in-c57bl-6j-mice
#17
Atsushi Toyoda, Hikari Shimonishi, Mizuho Sato, Kento Usuda, Natsuki Ohsawa, Kentaro Nagaoka
Diverse commercially available feeds are used in animal studies according to the purpose of the studies. We sought to understand the relationship between feed ingredients and their effects on animal physiology and behaviors. Here, we investigated how male laboratory mice (C57BL/6J ("B6") mice) were affected by chronic feeding with two commercially available diets, a non-purified diet (MF) and a semi-purified diet (AIN-93G). In B6 mice, both diets similarly induced spontaneous activities in the home cage and the open field box, anxiety in the elevated plus maze test, and depressive-like behaviors in tail-suspension and forced-swimming tests, and with both diets, similar data were obtained on calorie intake, water intake, body weight gain, and plasma corticosterone levels...
March 23, 2018: Neuroscience Letters
https://www.readbyqxmd.com/read/29355556/chrysin-reverses-the-depressive-like-behavior-induced-by-hypothyroidism-in-female-mice-by-regulating-hippocampal-serotonin-and-dopamine
#18
Vandreza Cardoso Bortolotto, Franciane Cabral Pinheiro, Stífani Machado Araujo, Márcia Rósula Poetini, Bianca Santos Bertolazi, Mariane Trindade de Paula, Luana Barreto Meichtry, Francielli Polet de Almeida, Shanda de Freitas Couto, Cristiano Ricardo Jesse, Marina Prigol
Hypothyroidism is often associated with psychiatric disorders such as depression. In this study, we evaluated the effect of chrysin on depressive-like behavior and monoamine levels in hypothyroid female mice. Hypothyroidism was induced by continuous exposure to 0.1% methimazole (MTZ) in drinking water for 31 days. Exposure to MTZ was associated with low plasma levels of thyroid hormones T3 and T4 compared with the control group. Subsequently, euthyroid and MTZ-induced hypothyroid mice were intragastrically administered vehicle or chrysin (20mg/kg) once a day for 28 consecutive days...
March 5, 2018: European Journal of Pharmacology
https://www.readbyqxmd.com/read/29352267/differential-susceptibility-of-striatal-hippocampal-and-cortical-neurons-to-caspase-6
#19
Anastasia Noël, Libin Zhou, Bénédicte Foveau, P Jesper Sjöström, Andréa C LeBlanc
Active cysteinyl protease Caspase-6 is associated with early Alzheimer and Huntington diseases. Higher entorhinal cortex and hippocampal Caspase-6 levels correlate with lower cognitive performance in aged humans. Caspase-6 induces axonal degeneration in human primary neuron cultures and causes inflammation and neurodegeneration in mouse hippocampus, and age-dependent memory impairment. To assess whether Caspase-6 causes damage to another neuronal system, a transgenic knock-in mouse overexpressing a self-activated form of Caspase-6 five-fold in the striatum, the area affected in Huntington disease, and 2...
January 19, 2018: Cell Death and Differentiation
https://www.readbyqxmd.com/read/29210119/diets-rich-in-saturated-fat-and-fructose-induce-anxiety-and-depression-like-behaviours-in-the-rat-is-there-a-role-for-lipid-peroxidation
#20
Silvia Gancheva, Bistra Galunska, Maria Zhelyazkova-Savova
Epidemiological studies reveal associations between obesity/metabolic syndrome and mood disorders. We assessed behavioural changes in rats fed diets enriched in fat and fructose in different proportions and correlated the observed alterations with biochemical changes induced by the diets. Three groups of rats were used as follows: control (C) animals fed regular rat chow, rats fed high-fat diet (HF) and rats fed high-fat and high-fructose diet (HFHF). HF and HFHF animals were also given a 10% fructose solution as drinking water...
October 2017: International Journal of Experimental Pathology
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