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https://www.readbyqxmd.com/read/28054115/-risk-and-benefit-of-nutritional-supplements-for-the-treatment-of-postmenopausal-complaints
#1
Patrick Diel, Anne Kurrat, Christina Oden, Lars Hanke
Menopause is for many females associated with an occurrence of a variety of health complaints and a decrease in quality in life. Hot flashes, sleep disturbances and a variety of other symptoms result in a strong psychological strain. Hormone replacement therapy for treatment of climacteric complaints is discussed controversially regarding associated side effects. This is a major reason to propose treatment with plant derived extracts and compounds as an alternative. Such compounds are available either as drugs but mostly as nutritional supplements...
January 4, 2017: Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz
https://www.readbyqxmd.com/read/28045144/adsorbate-interactions-on-the-gan-0001-surface-and-their-effect-on-diffusion-barriers-and-growth-morphology
#2
Manjusha Chugh, Madhav Ranganathan
Studying the adsorbate interactions on a surface helps in understanding the growing surface morphologies and calculating the effective surface diffusion barriers. We study the interaction between Ga-Ga, N-N and Ga-N adatom pairs on the polar GaN(0001) surface using ab initio calculations based on density functional theory. The interaction energy between two adatoms on the surface does not seem to follow definite trends with increasing distance between the adatoms. The presence of a number of possible reconstructions on clean GaN(0001) and periodic effects due to the finite size complicate the analysis of the interactions...
January 3, 2017: Physical Chemistry Chemical Physics: PCCP
https://www.readbyqxmd.com/read/28038341/standing-balance-and-inter-limb-balance-asymmetry-at-one-year-post-primary-anterior-cruciate-ligament-reconstruction-sex-differences-in-a-cohort-study-of-414-patients
#3
Ross A Clark, Stuart W Bell, Julian A Feller, Timothy S Whitehead, Kate E Webster
BACKGROUND: Static standing balance can be safely assessed early following anterior cruciate ligament reconstruction (ACLR), and deficits may have important implications for long-term outcomes. This study includes a large cohort of people post-ACLR and has the primary aim of establishing whether inter-limb and sex differences exist, with a secondary aim of assessing the association between static balance variables and other outcome measures. METHODS: A total of 414 patients with a primary ACLR performed a 30-s static single leg balance test...
December 16, 2016: Gait & Posture
https://www.readbyqxmd.com/read/28036030/xanthohumol-a-prenylated-chalcone-from-hops-inhibits-the-viability-and-stemness-of-doxorubicin-resistant-mcf-7-adr-cells
#4
Ming Liu, Hua Yin, Xiaokun Qian, Jianjun Dong, Zhonghua Qian, Jinlai Miao
Xanthohumol is a unique prenylated flavonoid in hops (Humulus lupulus L.) and beer. Xanthohumol has been shown to possess a variety of pharmacological activities. There is little research on its effect on doxorubicin-resistant breast cancer cells (MCF-7/ADR) and the cancer stem-like cells exiting in this cell line. In the present study, we investigate the effect of xanthohumol on the viability and stemness of MCF-7/ADR cells. Xanthohumol inhibits viability, induces apoptosis, and arrests the cell cycle of MCF-7/ADR cells in a dose-dependent manner; in addition, xanthohumol sensitizes the inhibition effect of doxorubicin on MCF-7/ADR cells...
December 28, 2016: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
https://www.readbyqxmd.com/read/27998667/validity-and-reliability-of-a-novel-instrumented-one-legged-hop-test-in-patients-with-knee-injuries
#5
Karin Mani, William F Brechue, Bernd Friesenbichler, Nicola A Maffiuletti
BACKGROUND: Conventional one-legged hop tests simply evaluate the total hop distance, thus neglecting important temporal and spatial parameters related to the strategy of execution, such as foot contact time. AIM: To examine the validity and reliability of an instrumented one-legged hop test, the "four hops, three contacts" (4H3C) test, in patients with knee injuries. METHODS: The 4H3C test consists of four consecutive one-legged hops, of which individual hop distance and foot contact time are recorded by a validated floor-based photocell system...
December 17, 2016: Knee
https://www.readbyqxmd.com/read/27904796/functional-hop-tests-and-tuck-jump-assessment-scores-between-female-division-i-collegiate-athletes-participating-in-high-versus-low-acl-injury-prone-sports-a-cross-sectional-analysis
#6
Philipp Hoog, Meghan Warren, Craig A Smith, Nicole J Chimera
BACKGROUND: Although functional tests including the single leg hop (SLH), triple hop (TH), cross over hop (COH) for distance, and the tuck jump assessment (TJA) are used for return to play (RTP) criteria for post anterior cruciate ligament (ACL) injury, sport-specific baseline measurements are limited. PURPOSE: The purpose of this study was to examine differences in SLH, TH, and COH distance and limb symmetry index (LSI), as well as total scores, number of jumps, and individual flaws of the TJA in 97 injury-free Division I (DI) collegiate female student athletes participating in ACL injury prone vs...
December 2016: International Journal of Sports Physical Therapy
https://www.readbyqxmd.com/read/27893474/hypertrophy-and-explosive-reactive-functioning-in-sedentary-men-following-10-weeks-of-whole-body-vibration
#7
Jens Ebing, Ulf Gast, Christoph Hauptmann, Dieter Felsenberg, Daniel L Belavý
The objective of this study was to determine the impact of vertical (Power-plate; POW) and side-alternating (Galileo; GAL) whole-body vibration exercise on muscle mass and lower-limb neuromuscular function. Forty-three sedentary male subjects (18-30yr) randomized into three groups underwent two upper-body exercise sessions per week for 10 weeks. Two groups of subjects underwent additional squat exercises on the GAL (N=15) or POW (N=14) devices. The third group was control. On magnetic resonance imaging, volume of the thigh muscles was measured...
November 16, 2016: Journal of Strength and Conditioning Research
https://www.readbyqxmd.com/read/27869529/low-fundamental-movement-skill-proficiency-is-associated-with-high-bmi-and-body-fatness-in-girls-but-not-boys-aged-6-11-years-old
#8
Michael J Duncan, Elizabeth Bryant, David Stodden
This study examined differences in children's body mass index (BMI) and body fatness (BF%) as a function of gender and fundamental movement skill (FMS) proficiency. Following ethics approval and parental consent, 248, 6-11 year-old children (112 boys, 136 girls) underwent assessment of 7 FMS: sprint run, side gallop, hop, kick, catch, throw and vertical jump. FMS tertiles ("high", "medium" or "low" FMS) were created based on the summed components of the FMS. Skinfold measures were used to calculate BF%. Physical activity (PA) was assessed using pedometry and maturation predicted using anthropometry...
November 21, 2016: Journal of Sports Sciences
https://www.readbyqxmd.com/read/27837221/femoral-avulsion-fracture-of-acl-proximal-attachment-in-male-scuba-diver-case-report-and-review-of-the-literature
#9
Sebastian Zabierek, Krzysztof Nowak, Marcin Domzalski
Femoral ACL avulsion fractures were not well described in the literature, and there were only several reports describing mostly immature patients. A case of 50-year-old man with ACL femoral attachment avulsion fracture after pivoting knee injury during skiing was presented. The bony attachment was reduced and fixed arthroscopically with screws. Four months after surgery, patient was allowed to return to full sport activity with full range of motion. He was able to perform a one-leg-hop test without limitation, and the strength of quadriceps muscle was comparable to contralateral side...
November 11, 2016: Knee Surgery, Sports Traumatology, Arthroscopy: Official Journal of the ESSKA
https://www.readbyqxmd.com/read/27834590/clinical-effects-of-dry-needling-among-asymptomatic-individuals-with-hamstring-tightness-a-randomized-controlled-trial
#10
Kathleen Geist, Claire Bradley, Alan Hofman, Rob Koester, Fenella Roche, Annalise Shields, Elizabeth Frierson, Ainsley Rossi, Marie Johanson
STUDY DESIGN: Randomized controlled trial. OBJECTIVES: The aim of this study was to determine the effects of dry needling on hamstring extensibility and functional performance tests among asymptomatic individuals with hamstring muscle tightness. BACKGROUND: Dry needling has been shown to increase range of motion in the upper quarter and may have similar effects in the lower quarter. METHODS: Twenty-seven subjects with hamstring extensibility deficits were randomly assigned to side of treatment (dominant or non-dominant) and group (blunt needling or dry needling)...
November 11, 2016: Journal of Sport Rehabilitation
https://www.readbyqxmd.com/read/27821609/structure-and-mechanism-of-the-atp-synthase-membrane-motor-inferred-from-quantitative-integrative-modeling
#11
Vanessa Leone, José D Faraldo-Gómez
Two subunits within the transmembrane domain of the ATP synthase-the c-ring and subunit a-energize the production of 90% of cellular ATP by transducing an electrochemical gradient of H(+) or Na(+) into rotational motion. The nature of this turbine-like energy conversion mechanism has been elusive for decades, owing to the lack of definitive structural information on subunit a or its c-ring interface. In a recent breakthrough, several structures of this complex were resolved by cryo-electron microscopy (cryo-EM), but the modest resolution of the data has led to divergent interpretations...
December 2016: Journal of General Physiology
https://www.readbyqxmd.com/read/27816530/structural-basis-of-transport-function-in-major-facilitator-superfamily-protein-from-trichoderma-harzianum
#12
Nitika Chaudhary, Padmani Sandhu, Mushtaq Ahmed, Yusuf Akhter
Trichothecenes are the sesquiterpenes secreted by Trichoderma spp. residing in the rhizosphere. These compounds have been reported to act as plant growth promoters and bio-control agents. The structural knowledge for the transporter proteins of their efflux remained limited. In this study, three-dimensional structure of Thmfs1 protein, a trichothecene transporter from Trichoderma harzianum, was homology modelled and further Molecular Dynamics (MD) simulations were used to decipher its mechanism. Fourteen transmembrane helices of Thmfs1 protein are observed contributing to an inward-open conformation...
February 2017: International Journal of Biological Macromolecules
https://www.readbyqxmd.com/read/27802796/patients-with-chondrolabral-pathology-have-bilateral-functional-impairments-12-to-24-months-after-unilateral-hip-arthroscopy-a-cross-sectional-study
#13
Joanne L Kemp, May Arna Risberg, Anthony G Schache, Michael Makdissi, Michael G Pritchard, Kay M Crossley
Study Design Cross-sectional study. Background Functional task performance in patients with chondrolabral pathology following hip arthroscopy is unknown. Objectives To investigate in people with chondrolabral pathology following hip arthroscopy (1) the bilateral differences in functional task performance compared to controls, (2) the association of hip muscle strength with functional task performance, and (3) the association of functional task performance scores with good outcome, as measured by International Hip Outcome Tool score...
November 2016: Journal of Orthopaedic and Sports Physical Therapy
https://www.readbyqxmd.com/read/27799670/correlation-between-hip-function-and-knee-kinematics-evaluated-by-three-dimensional-motion-analysis-during-lateral-and-medial-side-hopping
#14
Hiromitsu Itoh, Kohei Takiguchi, Yohei Shibata, Satoshi Okubo, Shinichi Yoshiya, Ryosuke Kuroda
[Purpose] Kinematic and kinetic characteristics of the limb during side-hopping and hip/knee interaction during this motion have not been clarified. The purposes of this study were to examine the biomechanical parameters of the knee during side hop and analyze its relationship with clinical measurements of hip function. [Subjects and Methods] Eleven male college rugby players were included. A three-dimensional motion analysis system was used to assess motion characteristics of the knee during side hop. In addition, hip range of motion and muscle strength were evaluated...
September 2016: Journal of Physical Therapy Science
https://www.readbyqxmd.com/read/27756572/musculoskeletal-modeling-of-human-lower-limb-during-normal-walking-one-legged-forward-hopping-and-side-jumping-comparison-of-measured-emg-and-predicted-muscle-activity-patterns
#15
A D Wibawa, N Verdonschot, J P K Halbertsma, J G M Burgerhof, R L Diercks, G J Verkerke
This study focused on comparing muscle activities predicted by the Musculoskeletal Modeling System with EMG from ten healthy subjects who performed normal walking, one-legged forward hopping and side jumping. Eight EMG electrodes measured the activity of eight right leg muscles. Specific thresholds per muscle were applied on the EMG prior comparison. These thresholds were determined by equalizing the duration of EMG to AMS muscle activity. Three graph variables, number of onsets, offsets and hills were used to quantify the level of agreement by using Cohen׳s kappa analysis...
October 6, 2016: Journal of Biomechanics
https://www.readbyqxmd.com/read/27676865/functional-tests-can-they-help-in-the-decision-to-return-to-sports-after-anterior-cruciate-ligament-example-with-hop-tests
#16
Alexandre Rambaud, Pierre Samozino, Pascal Edouard
OBJECTIVE: After anterior cruciate ligament (ACL) tear, the ACL reconstruction (ACLR) is the standard treatment to return to pivots/contacts sports. The goal of rehabilitation programs is to guide the functional recovery and the safe return to sport without additional knee injury or other injuries. Functional tests, like Hop tests and their side to-side difference index [limb symmetry index (LSI)], are commonly used following ACLR to help return to sport decision making. However, the most commonly used criterion to return to sport is the postoperative time: return to light activities (RtlA) at 3 or 4 month mark and return to sport with contacts and side-cuttings (RtS) between 6 and 9 month mark...
September 2016: Annals of Physical and Rehabilitation Medicine
https://www.readbyqxmd.com/read/27676864/interest-of-a-biomechanical-analysis-of-running-on-a-treadmill-coupled-with-functional-testing-and-isokinetic-evaluation-during-return-to-sport-after-anterior-cruciate-ligament-reconstruction
#17
Alexandre Rambaud, Bertrand Semay, Jean-Benoit Morin, Rémi Phillipot, Pierre Samozino, Pascal Edouard
OBJECTIVE: A criterion of the anterior cruciate ligament reconstruction (ACLR) success is the return to sport at the same level as before surgery. Return to sport (RtS) decision seems to be a key element in this success: if too early RtS exposes to risk of injury, too late RtS influences the motivation to return to the same level. Functional tests (Hop Tests) and isokinetic assessments (Isok Tests) are usually performed to guide this decision. However, a precise and objective biomechanical analysis of running pattern would be more similarly to the sport activity...
September 2016: Annals of Physical and Rehabilitation Medicine
https://www.readbyqxmd.com/read/27665093/an-anterior-cruciate-ligament-injury-does-not-affect-the-neuromuscular-function-of-the-non-injured-leg-except-for-dynamic-balance-and-voluntary-quadriceps-activation
#18
Tjerk Zult, Alli Gokeler, Jos J A M van Raay, Reinoud W Brouwer, Inge Zijdewind, Tibor Hortobágyi
PURPOSE: The function of the anterior cruciate ligament (ACL) patients' non-injured leg is relevant in light of the high incidence of secondary ACL injuries on the contralateral side. However, the non-injured leg's function has only been examined for a selected number of neuromuscular outcomes and often without appropriate control groups. We measured a broad array of neuromuscular functions between legs of ACL patients and compared outcomes to age, sex, and physical activity matched controls...
September 24, 2016: Knee Surgery, Sports Traumatology, Arthroscopy: Official Journal of the ESSKA
https://www.readbyqxmd.com/read/27634270/electrolyte-gated-charge-transport-in-molecularly-linked-gold-nanoparticle-films-the-transition-from-a-mott-insulator-to-an-exotic-metal-with-strong-electron-electron-interactions
#19
M Tie, A-A Dhirani
Strong electron-electron interactions experienced by electrons as they delocalize are widely believed to play a key role in a range of remarkable phenomena such as high Tc superconductivity, colossal magnetoresistance, and others. Strongly correlated electrons are often described by the Hubbard model, which is the simplest description of a correlated system and captures important gross features of phase diagrams of strongly correlated materials. However, open challenges in this field include experimentally mapping correlated electron phenomena beyond those captured by the Hubbard model, and extending the model accordingly...
September 14, 2016: Journal of Chemical Physics
https://www.readbyqxmd.com/read/27632874/a-randomized-controlled-trial-comparing-rehabilitation-efficacy-in-chronic-ankle-instability
#20
Cynthia J Wright, Shelley W Linens, Mary Spencer Cain
CONTEXT: There is minimal patient-oriented evidence regarding the effectiveness of interventions targeted to reduce symptoms associated with chronic ankle instability (CAI). Additionally, clinicians aiming to prioritize care by implementing only the most effective components of a rehabilitative program have very little evidence on comparative efficacy. OBJECTIVE: To assess the comparative efficacy of two common ankle rehabilitation techniques [wobble board (WB) balance training and ankle strengthening using resistance tubing (RT)] using patient-oriented outcomes...
August 24, 2016: Journal of Sport Rehabilitation
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