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https://www.readbyqxmd.com/read/27908572/significant-treatment-effect-of-add-on-ketamine-anesthesia-in-electroconvulsive-therapy-in-depressive-patients-a-meta-analysis
#1
Dian-Jeng Li, Fu-Chiang Wang, Che-Sheng Chu, Tien-Yu Chen, Chia-Hung Tang, Wei-Cheng Yang, Philip Chik-Keung Chow, Ching-Kuan Wu, Ping-Tao Tseng, Pao-Yen Lin
Add-on ketamine anesthesia in electroconvulsive therapy (ECT) has been studied in depressive patients in several clinical trials with inconclusive findings. Two most recent meta-analyses reported insignificant findings with regards to the treatment effect of add-on ketamine anesthesia in ECT in depressive patients. The aim of this study is to update the current evidence and investigate the role of add-on ketamine anesthesia in ECT in depressive patients via a systematic review and meta-analysis. We performed a thorough literature search of the PubMed and ScienceDirect databases, and extracted all relevant clinical variables to compare the antidepressive outcomes between add-on ketamine anesthesia and other anesthetics in ECT...
November 28, 2016: European Neuropsychopharmacology: the Journal of the European College of Neuropsychopharmacology
https://www.readbyqxmd.com/read/27828927/effect-of-low-dose-of-ketamine-on-learning-memory-function-in-patients-undergoing-electroconvulsive-therapy-a-randomized-double-blind-controlled-clinical-study
#2
Qibin Chen, Su Min, Xuechao Hao, Lihua Peng, Huaqing Meng, Qinghua Luo, Jianmei Chen, Xiao Li
OBJECTIVES: Converging evidence suggests that low doses of ketamine have antidepressant effects. The feasibility and safety of administering low doses of ketamine as adjunctive medication during electroconvulsive therapy (ECT) to enhance ECT efficacy and mitigate cognitive impairment has attracted much attention. This study investigated the effects of low doses of ketamine on learning and memory in patients undergoing ECT under propofol anesthesia. METHODS: This randomized, placebo-controlled, double-blind study recruited patients with moderate to severe depressive disorders who failed to respond to antidepressants and were scheduled to receive ECT...
November 3, 2016: Journal of ECT
https://www.readbyqxmd.com/read/27753760/the-trend-of-adding-remifentanil-in-ect-anesthesia-what-are-we-doing
#3
Albert Bortolotti
No abstract text is available yet for this article.
December 2016: Journal of ECT
https://www.readbyqxmd.com/read/27522170/based-on-a-true-story-the-portrayal-of-ect-in-international-movies-and-television-programs
#4
Pascal Sienaert
BACKGROUND: Movies and television (TV) programs are an important source of public information about ECT. OBJECTIVE: To narratively review the portrayal of ECT in international movies and TV programs from 1948 until present. METHODS: Several Internet movie databases and a database of phrases appearing in movies and TV programs were searched, supplemented with a Medline-search. No language restrictions were applied. RESULTS: ECT was portrayed in 52 movies (57 scenes), 21 TV programs (23 scenes), and 2 animated sitcoms (2 scenes)...
November 2016: Brain Stimulation
https://www.readbyqxmd.com/read/27513252/sevoflurane-versus-propofol-for-electroconvulsive-therapy-effects-on-seizure-parameters-anesthesia-recovery-and-the-bispectral-index
#5
Melekşah Pekel, Nadide Aysun Postaci, İsmail Aytaç, Derya Karasu, Hüseyin Keleş, Özlem Şen, Bayazit Dikmen, Erol Göka
BACKGROUND/AIM: In this prospective randomized cross-over study we compare the effects of sevoflurane versus propofol for electroconvulsive therapy (ECT) anesthesia. MATERIALS AND METHODS: Twenty four patients (ASA I-III, 18-65 years old) receiving ECT three times per week were included. Anesthesia was induced with either propofol (0.75 mg/kg iv) or 5% sevoflurane in 100% oxygen. Consecutive ECT sessions followed a 2 × 2 crossover design and a 2-day washout period until the 10th ECT...
2016: Turkish Journal of Medical Sciences
https://www.readbyqxmd.com/read/27385857/how-bad-was-unmodified-electroconvulsive-therapy-a-retrospective-study
#6
Anindya Kumar Ray
"Unmodified"-electroconvulsive therapy (ECT) being considered unethical remained away from the scientific literature, but continued in practice in many parts of the world. The Mental Health Care Bill, 2011, proposed for its banning in India. The aim of this study is to retrospectively observe "how bad was unmodified-ECT" to the patients in a naturalistic setting. The study was done at the Central Institute of Psychiatry, India. Files of patients receiving unmodified ECT during 1990-1995 were retrospectively reviewed...
April 2016: Indian Journal of Psychiatry
https://www.readbyqxmd.com/read/27239359/ectomesenchymal-chondromyxoid-tumour-of-the-dorsal-tongue-presenting-with-impaired-speech
#7
Laura A Schep, Martin J Bullock, S Mark Taylor
Ectomesenchymal chondromyxoid tumours (ECTs) are rare mesenchymal soft tissue neoplasms that typically present as a slow-growing asymptomatic mass on the anterior dorsum of the tongue. Our patient presented with impaired speech articulation and pain associated with upper respiratory tract infections when the lesion on his dorsal tongue would swell, and he would accidentally bite down on it. Microscopically, ECTs appear as unencapsulated, well-circumscribed proliferations of uniform round to fusiform cells embedded within chondromyxoid matrices...
2016: Case Reports in Otolaryngology
https://www.readbyqxmd.com/read/27208499/mood-and-neuropsychological-effects-of-different-doses-of-ketamine-in-electroconvulsive-therapy-for-treatment-resistant-depression
#8
Xiaomei Zhong, Hongbo He, Chunping Zhang, Zhijie Wang, Miaoling Jiang, Qirong Li, Minling Zhang, Xiong Huang
BACKGROUND: Treatment-resistant depression (TRD) is a growing clinical challenge. Electroconvulsive therapy (ECT) is an effective tool for TRD treatment. However, there remains a subset of patients who do not respond to this treatment with common anesthetic agent. Ketamine, a noteworthy anesthetic agent, has emerged as an augmentation to enhance the antidepressant efficacy of ECT. Trials of i.v. ketamine in TRD indicated dose-related mood enhancing efficacy. We aimed to explore anesthetic and subanesthetic concentrations of ketamine in ECT for TRD with respect to their impact on mood and neuropsychological effects...
September 1, 2016: Journal of Affective Disorders
https://www.readbyqxmd.com/read/27153810/a-case-of-malignant-catatonia-with-idiopathic-pulmonary-arterial-hypertension-treated-by-electroconvulsive-therapy
#9
Mizue Hobo, Akihito Uezato, Mitsunori Nishiyama, Mayumi Suzuki, Jiro Kurata, Koshi Makita, Naoki Yamamoto, Toru Nishikawa
BACKGROUND: Idiopathic pulmonary arterial hypertension (IPAH) is a progressive and fatal cardiovascular disease if left untreated. In patients with IPAH with psychiatric illness or other complications, careful attention is required when administering medical therapies that may affect their hemodynamics. Patients suffering from IPAH who undergo anesthesia and surgery have a high mortality and morbidity rate. We describe the treatment of intractable psychiatric symptoms with electroconvulsive therapy (ECT) in a patient with IPAH...
2016: BMC Psychiatry
https://www.readbyqxmd.com/read/27115120/subgenual-cingulate-cortical-activity-predicts-the-efficacy-of-electroconvulsive-therapy
#10
M Argyelan, T Lencz, S Kaliora, D K Sarpal, N Weissman, P B Kingsley, A K Malhotra, G Petrides
Electroconvulsive therapy (ECT) is the most effective treatment for depression, yet its mechanism of action is unknown. Our goal was to investigate the neurobiological underpinnings of ECT response using longitudinally collected resting-state functional magnetic resonance imaging (rs-fMRI) in 16 patients with treatment-resistant depression and 10 healthy controls. Patients received bifrontal ECT 3 times a week under general anesthesia. We acquired rs-fMRI at three time points: at baseline, after the 1st ECT administration and after the course of the ECT treatment; depression was assessed with the Hamilton Depression Rating Scale (HAM-D)...
2016: Translational Psychiatry
https://www.readbyqxmd.com/read/27008331/representations-of-ect-in-english-language-film-and-television-in-the-new-millennium
#11
Avery Madeleine Matthews, Peter B Rosenquist, William Vaughn McCall
OBJECTIVE: The aim of the study was to survey the media landscape to determine whether visual depictions of electroconvulsive therapy (ECT) are becoming more or less medically accurate in the new millennium. METHOD: English-language film and television shows depicting ECT were analyzed for patient demographics, administrator roles, indication, consent, anesthesia, paralytics, bite block, lead placement, electroencephalogram, and outcome. RESULTS: Thirty-nine ECT scenes were viewed, and just 3 included all 5 essential tools of modern ECT: anesthesia, paralytic, electrodes, electroencephalogram, and a bite block...
September 2016: Journal of ECT
https://www.readbyqxmd.com/read/27008330/ketamine-anesthesia-efficacy-of-electroconvulsive-therapy-and-cognitive-functions-in-treatment-resistant-depression
#12
Janusz K Rybakowski, Anna Bodnar, Milosz Krzywotulski, Maria Chlopocka-Wozniak, Michal Michalak, Jowita Rosada-Kurasinska, Alicja Bartkowska-Sniatkowska
OBJECTIVES: Electroconvulsive therapy (ECT) is the most effective treatment for drug-resistant depression (DRD). Because a single infusion of ketamine may exert both a rapid antidepressant effect and a quick improvement of cognition, the aim of the present study was to assess whether ketamine, as an anesthetic drug for ECT, can augment the antidepressant activity of the procedure and/or exert a beneficial effect on cognition. METHODS: A total of 11 male and 34 female patients with DRD, aged 21 to 75 years, were included in the study...
September 2016: Journal of ECT
https://www.readbyqxmd.com/read/26822480/remifentanil-in-electroconvulsive-therapy-a-systematic-review-and-meta-analysis-of-randomized-controlled-trials
#13
Yoshiteru Takekita, Taro Suwa, Naotaka Sunada, Hirotsugu Kawashima, Chiara Fabbri, Masaki Kato, Aran Tajika, Toshihiko Kinoshita, Toshi A Furukawa, Alessandro Serretti
In electroconvulsive therapy (ECT), remifentanil is often used concurrently with anesthetics. The objective of this study was to provide an up-to-date and comprehensive review on how the addition of remifentanil to anesthetics affects seizure duration and circulatory dynamics in mECT. We performed a meta-analysis of RCTs that investigated seizure duration and circulatory dynamics in patients treated with ECT using anesthetics alone (non-remifentanil group) and with anesthetics plus remifentanil (remifentanil group)...
January 28, 2016: European Archives of Psychiatry and Clinical Neuroscience
https://www.readbyqxmd.com/read/26807625/improving-the-medical-assessment-of-patients-before-electroconvulsive-therapy-an-audit-across-two-sites
#14
Hannah R Driver
OBJECTIVE: It is essential that a medical assessment is completed before commencing electroconvulsive therapy (ECT) to identify possible risk factors that may complicate anesthesia. This audit aimed to improve the physical examination and documented medical history of this assessment usually performed by referring psychiatrists. METHODS: Patients from 2 sites (A and B) were retrospectively audited against standards from the Scottish ECT Accreditation Network. The timing and systems examined for the physical examination were noted...
June 2016: Journal of ECT
https://www.readbyqxmd.com/read/26573499/-clinical-characteristics-of-276-patients-treated-with-electroconvulsive-therapy-at-a-university-clinic-in-medell%C3%A3-n-colombia
#15
María Victoria Ocampo, Clara Isabel Ramírez, José G Franco, Lina María Gómez, Gloria Cardona, Carolina Restrepo
OBJECTIVE: To describe the socio-demographic and clinical characteristics of patients undergoing Electroconvulsive Therapy with Anesthesia and Relaxation (ECTAR) for 10 years in a university clinic. METHODOLOGY: Review of 276 medical records of patients who had undergone ECTAR between 1997 and 2007 at the Clínica Universitaria Bolivariana de Medellín, Colombia. Data was collected through an instrument designed for that purpose and then was analyzed. RESULTS: During 10 years, more than 2000 ECT procedures were performed; most of the patients were female 67...
June 2012: Revista Colombiana de Psiquiatría
https://www.readbyqxmd.com/read/26508965/increases-in-ips-transcription-factor-oct4-sox2-c-myc-and-klf4-gene-expression-after-modified-electroconvulsive-therapy
#16
Masaki Nishiguchi, Hiroki Kikuyama, Tetsufumi Kanazawa, Atsushi Tsutsumi, Takao Kaneko, Hiroyuki Uenishi, Yasuo Kawabata, Seiya Kawashige, Jun Koh, Hiroshi Yoneda
OBJECTIVE: Electroconvulsive therapy (ECT) is a reasonable option for intractable depression or schizophrenia, but a mechanism of action has not been established. One credible hypothesis is related to neural plasticity. Three genes (Oct4, Sox2, c-Myc) involved in the induction of induced pluripotent stem (iPS) cells are Wnt-target genes, which constitute a key gene group involved in neural plasticity through the TCF family. Klf4 is the other gene among Yamanaka's four transcription factors, and increases in its expression are induced by stimulation of the canonical Wnt pathway...
October 2015: Psychiatry Investigation
https://www.readbyqxmd.com/read/26440233/impact-comparison-of-ketamine-and-sodium-thiopental-on-anesthesia-during-electroconvulsive-therapy-in-major-depression-patients-with-drug-resistant-a-double-blind-randomized-clinical-trial
#17
RANDOMIZED CONTROLLED TRIAL
B Salehi, A Mohammadbeigi, A R Kamali, M R Taheri-Nejad, I Moshiri
BACKGROUND: Electroconvulsive therapy (ECT) is one of the available and the most effective therapies for the treatment of resistant depression. Considering the crucial role of seizure duration on therapeutic response in patients treated with ECT, this study aimed to compare the effect of ketamine and sodium thiopental anesthesia during ECT for treatment of patients with drug-resistant major depression (DRMD). MATERIALS AND METHODS: In a double-blind randomized clinical trial, 160 patients with DRMD were selected consequently and were assigned randomly into two groups including ketamine 0...
October 2015: Annals of Cardiac Anaesthesia
https://www.readbyqxmd.com/read/26383207/seizure-duration-and-hemodynamic-state-during-electroconvulsive-therapy-sodium-thiopental-versus-propofol
#18
RANDOMIZED CONTROLLED TRIAL
Hashem Jarineshin, Saeed Kashani, Fereydoon Fekrat, Majid Vatankhah, Javad Golmirzaei, Esmaeel Alimolaee, Hamid Zafarpour
INTRODUCTION: General anesthesia is required for Electroconvulsive Therapy (ECT) and it is usually provided by a hypnotic agent. The seizure duration is important for the treatment, and it is usually accompanied by severe hemodynamic changes. The aim of this study was to compare the effects of sodium thiopental versus Propofol on seizure duration and hemodynamic variables during ECT. METHODS: A number of 100 patient-sessions of ECT were included in this randomized clinical trial...
2016: Global Journal of Health Science
https://www.readbyqxmd.com/read/26376042/electrochemotherapy-in-non-melanoma-head-and-neck-skin-cancers-a-three-centers-experience-and-literature-review
#19
R Rotunno, F Marenco, S Ribero, S Calvieri, P Amerio, P Curatolo, P Quaglino
AIM: The main purposes of this study were to evaluate the efficacy of electrochemotherapy in head and neck tumours, to assess the local tumour control, the safety profile and its impact on the patients' quality of life. METHODS: This is a multicenter prospective, non-randomized phase II trial. This trial was carried out at the Dermatologic Clinic of University of Rome "La Sapienza", at the Dermatologic Clinic of University of Chieti and at the Dermatologic Clinic of University of Turin...
September 16, 2015: Giornale Italiano di Dermatologia e Venereologia: Organo Ufficiale, Società Italiana di Dermatologia e Sifilografia
https://www.readbyqxmd.com/read/26192904/electroporation-enhances-bleomycin-efficacy-in-cats-with-periocular-carcinoma-and-advanced-squamous-cell-carcinoma-of-the-head
#20
E P Spugnini, M Pizzuto, M Filipponi, L Romani, B Vincenzi, F Menicagli, A Lanza, R De Girolamo, R Lomonaco, M Fanciulli, G Spriano, A Baldi
BACKGROUND: Advanced carcinoma of the head represents a substantial health problem in cats for local control and overall survival. OBJECTIVES: Evaluate the capability of electrochemotherapy (ECT) to improve bleomycin efficacy in cats with periocular carcinoma and advanced carcinoma of the head. ANIMALS: Twenty-one cats with periocular carcinoma (17 squamous cell carcinoma [SCC] and 4 anaplastic carcinoma) and 26 cats with advanced SCC of the head...
September 2015: Journal of Veterinary Internal Medicine
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