keyword
https://read.qxmd.com/read/38546931/high-frequency-of-transient-congenital-hypothyroidism-among-infants-referred-for-suspected-congenital-hypothyroidism-from-the-turkish-national-screening-program-thyroxine-dose-may-guide-the-prediction-of-transients
#1
JOURNAL ARTICLE
Y Özer, A Anık, U Sayılı, U Tercan, R Deveci Sevim, S Güneş, M Buhur Pirimoğlu, S Elmaoğulları, I Dündar, D Ökdemir, Ö Besci, A Jalilova, D Çiçek, B Singin, Ş E Ulu, H Turan, S Albayrak, Z Kocabey Sütçü, B S Eklioğlu, E Eren, S Çetinkaya, Ş Savaş-Erdeve, I Esen, K Demir, Ş Darcan, N Hatipoğlu, M Parlak, F Dursun, Z Şıklar, M Berberoğlu, M Keskin, Z Orbak, B Tezel, E Yürüker, B Keskinkılıç, F Kara, E Erginöz, F Darendeliler, O Evliyaoğlu
PURPOSE: We aimed to determine the frequency of transient congenital hypothyroidism (TCH) in 17 participating centers in Türkiye, evaluate the etiological distribution in permanent congenital hypothyroidism (PCH) cases, and investigate the role of laboratory and clinical findings in predicting TCH. METHODS: This retrospective observational multicenter study included patients from 17 pediatric endocrinology centers identified by "National Newborn Screening Program" (NNSP) who were born in 2015 and followed for 6 years...
March 28, 2024: Journal of Endocrinological Investigation
https://read.qxmd.com/read/38536822/immediate-postnatal-prediction-of-death-or-bronchopulmonary-dysplasia-among-very-preterm-and-very-low-birth-weight-infants-based-on-gradient-boosting-decision-trees-algorithm-a-nationwide-database-study-in-japan
#2
JOURNAL ARTICLE
Kota Yoneda, Tomohisa Seki, Yoshimasa Kawazoe, Kazuhiko Ohe, Naoto Takahashi
INTRODUCTION: Bronchopulmonary dysplasia (BPD) poses a substantial global health burden. Individualized treatment strategies based on early prediction of the development of BPD can mitigate preterm birth complications; however, previously suggested predictive models lack early postnatal applicability. We aimed to develop predictive models for BPD and mortality based on immediate postnatal clinical data. METHODS: Clinical information on very preterm and very low birth weight infants born between 2008 and 2018 was extracted from a nationwide Japanese database...
2024: PloS One
https://read.qxmd.com/read/38517437/antibiotic-use-in-late-preterm-and-full-term-newborns
#3
JOURNAL ARTICLE
Johan Gyllensvärd, Marie Studahl, Lars Gustavsson, Elisabet Hentz, Karin Åkesson, Huiqi Li, Mikael Norman, Anders Elfvin
IMPORTANCE: Antibiotic treatment saves lives in newborns with early-onset sepsis (EOS), but unwarranted antibiotic use is associated with resistant bacteria and adverse outcomes later in life. Surveillance is needed to optimize treatment strategies. OBJECTIVE: To describe antibiotic use in association with the incidence and mortality from EOS among late-preterm and full-term newborns. DESIGN, SETTING, AND PARTICIPANTS: The Sweden Neonatal Antibiotic Use study was a nationwide observational study that included all late-preterm and full-term neonates born from January 1, 2012, to December 31, 2020, in neonatal units of all levels...
March 4, 2024: JAMA Network Open
https://read.qxmd.com/read/38508661/clinical-cause-of-neonatal-mortality-in-iran-analysis-of-the-national-iranian-maternal-and-neonatal-network
#4
JOURNAL ARTICLE
Abbas Habibelahi, Mohammad Heidarzadeh, Leila Abdollahi, Majzoubeh Taheri, Saber Ghaffari-Fam, Roshanak Vakilian, Amin Daemi
BACKGROUND: The neonatal mortality rate is a main indicator of the health and development of a country. Having insight into the cause of neonatal deaths may be the first step to reducing it. This paper depicts the cause of newborn deaths in Iran. METHODS: This cross-sectional study was performed on data from the national Iranian Maternal And Neonatal network to investigate all neonatal deaths in the country during the year 2019. The cause of death data were reported according to categories of birth weight, gestational age (GA), death time and place...
March 20, 2024: BMJ Paediatrics Open
https://read.qxmd.com/read/38504293/women-s-autonomy-and-maternal-health-decision-making-in-kenya-implications-for-service-delivery-reform-a-qualitative-study
#5
JOURNAL ARTICLE
Easter Olwanda, Kennedy Opondo, Dorothy Oluoch, Kevin Croke, Justinah Maluni, Joyline Jepkosgei, Jacinta Nzinga
BACKGROUND: Maternal and neonatal outcomes in, Kakamega County is characterized by a maternal mortality rate of 316 per 100,000 live births and a neonatal mortality rate of 19 per 1,000 live births. In 2018, approximately 70,000 births occurred in the county, with 35% at home, 28% in primary care facilities, and 37% in hospitals. A maternal and child health service delivery redesign (SDR) that aims to reorganize maternal and newborn health services is being implemented in Kakamega County in Kenya to improve the progress of these indicators...
March 19, 2024: BMC Women's Health
https://read.qxmd.com/read/38503330/clinical-landscape-of-citrin-deficiency-a-global-perspective-on-a-multifaceted-condition
#6
JOURNAL ARTICLE
Jun Kido, Georgios Makris, Saikat Santra, Johannes Häberle
Citrin deficiency is an autosomal recessive disorder caused by a defect of citrin resulting from mutations in SLC25A13. The clinical manifestation is very variable and comprises three types: neonatal intrahepatic cholestasis caused by citrin deficiency (NICCD: OMIM 605814), post-NICCD including failure to thrive and dyslipidemia caused by citrin deficiency, and adult-onset type II citrullinemia (CTLN2: OMIM 603471). Frequently, NICCD can run with a mild clinical course and manifestations may resolve in the post-NICCD...
March 19, 2024: Journal of Inherited Metabolic Disease
https://read.qxmd.com/read/38486683/postnatal-growth-failure-of-very-low-birth-weight-infants-in-southwest-iran-a-descriptive-analytical-study
#7
JOURNAL ARTICLE
Masoud Dehdashtian, Mohammad-Reza Aramesh, Arash Malakian, Seyyed Mohammad Hassan Aletayeb, Amene Rasti
BACKGROUND AND AIMS: Preterm infants are more prone to poor growth and neurodevelopment. The first few weeks of life play an important role in the growth and neurodevelopment of very-low-birth-weight (VLBW) infants. The Vermont Oxford Network, evaluating the postnatal growth of preterm newborns, considers growth failure as body weight <10th percentile for postmenstrual age. This study aims to assess the frequency of postnatal growth failure in VLBW infants in Southwest Iran. METHODS: This descriptive analytical study was performed on VLBW infants in the neonatal intensive care unit (NICU) of Imam Khomeini Hospital (Ahvaz, Iran) from September 2019 to August 2020...
March 2024: Health Science Reports
https://read.qxmd.com/read/38482582/bilirubin-measurement-and-phototherapy-use-after-the-aap-2022-newborn-hyperbilirubinemia-guideline
#8
JOURNAL ARTICLE
Leela Sarathy, Joseph H Chou, Giuseppina Romano-Clarke, Katherine A Darci, Paul H Lerou
BACKGROUND AND OBJECTIVES: Guidelines for the management of neonatal hyperbilirubinemia have helped to reduce rates of significant hyperbilirubinemia. However, recent evidence suggesting overtreatment and potential harms of phototherapy have informed the American Academy of Pediatrics clinical practice guideline revision and the accompanying increase in phototherapy thresholds. These changes are predicted to safely reduce overuse; however, to date, the exact effect of these guidelines has not been established...
March 14, 2024: Pediatrics
https://read.qxmd.com/read/38471459/temporal-trends-in-severe-brain-injury-and-associated-outcomes-in-very-preterm-infants
#9
JOURNAL ARTICLE
Abdul Razak, Emily Johnston, Alice Stewart, Marissa A T Clark, Penelope Stevens, Margaret Charlton, Flora Wong, C McDonald, Rod W Hunt, Suzanne Miller, Atul Malhotra
INTRODUCTION: Severe brain injury (SBI), including severe intraventricular haemorrhage (sIVH) and cystic periventricular leukomalacia, poses significant challenges for preterm infants, yet recent data and trends are limited. METHODS: Analyses were conducted using the Australian and New Zealand Neonatal Network data on preterm infants born &lt;32 weeks' gestation admitted at Monash Children's Hospital, Australia, from January 2014 to April 2021. The occurrence and trends of SBI and sIVH among preterm infants, along with the rates and trends of death and neurodevelopmental impairment (NDI) in SBI infants were assessed...
March 12, 2024: Neonatology
https://read.qxmd.com/read/38470421/institutional-and-regional-variation-in-opioid-prescribing-for-hospitalized-infants-in-the-us
#10
JOURNAL ARTICLE
Olivia A Keane, Shadassa Ourshalimian, Ashwini Lakshmanan, Henry C Lee, Susan R Hintz, Nam Nguyen, Madeleine C Ing, Cynthia L Gong, Cameron Kaplan, Lorraine I Kelley-Quon
IMPORTANCE: High-risk infants, defined as newborns with substantial neonatal-perinatal morbidities, often undergo multiple procedures and require prolonged intubation, resulting in extended opioid exposure that is associated with poor outcomes. Understanding variation in opioid prescribing can inform quality improvement and best-practice initiatives. OBJECTIVE: To examine regional and institutional variation in opioid prescribing, including short- and long-acting agents, in high-risk hospitalized infants...
March 4, 2024: JAMA Network Open
https://read.qxmd.com/read/38460711/the-combined-contributions-of-newborn-stress-and-parenting-stress-on-toddler-language-development
#11
JOURNAL ARTICLE
Madeleine Bruce, Anna M Compton, Sarah E Maylott, Anna M Zhou, K Lee Raby, Sheila E Crowell, Elisabeth Conradt
OBJECTIVE: To examine the longitudinal associations between newborn neurobehavioral stress signs, maternal parenting stress, and several indices of toddler language development. STUDY DESIGN: Participants include 202 mother-infant dyads (104 girls). We measured stress signs in neonates in the hospital at least 24 hours after birth using the Neonatal Intensive Care Unit Network Neurobehavioral Scale. At 7 months, parenting stress (competence, attachment, and role restriction) was assessed using the Parenting Stress Index...
March 7, 2024: Journal of Pediatrics
https://read.qxmd.com/read/38457475/time-to-full-enteral-feeds-in-hospitalised-preterm-and-very-low-birth-weight-infants-in-nigeria-and-kenya
#12
JOURNAL ARTICLE
Zainab O Imam, Helen M Nabwera, Olukemi O Tongo, Pauline E A Andang'o, Isa Abdulkadir, Chinyere V Ezeaka, Beatrice N Ezenwa, Iretiola B Fajolu, Martha K Mwangome, Dominic D Umoru, Abimbola E Akindolire, Walter Otieno, Macrine Olwala, Grace M Nalwa, Alison W Talbert, Ismaela Abubakar, Nicholas D Embleton, Stephen J Allen
BACKGROUND: Preterm (born < 37 weeks' gestation) and very low birthweight (VLBW; <1.5kg) infants are at the greatest risk of morbidity and mortality within the first 28 days of life. Establishing full enteral feeds is a vital aspect of their clinical care. Evidence predominantly from high income countries shows that early and rapid advancement of feeds is safe and reduces length of hospital stay and adverse health outcomes. However, there are limited data on feeding practices and factors that influence the attainment of full enteral feeds among these vulnerable infants in sub-Saharan Africa...
2024: PloS One
https://read.qxmd.com/read/38457156/a-quality-improvement-strategy-to-reduce-unintended-extubation-in-the-very-low-birth-weight-infant-a-case-report
#13
JOURNAL ARTICLE
N Chahin, M S Yitayew, L Shaver, J L Reed, M Ridore, J Santoro, R R Moores, L Soghier, B Short, K D Hendricks-Muñoz
BACKGROUND: Unintended extubations remain a common complication across neonatal intensive care units, with very low birthweight infants being the most vulnerable of them all. Ongoing efforts across different institutions exist with the goal of reducing the rate of unintended extubations to keep a median rate of <2 events per 100 ventilator days as defined by the Vermont Oxford Network. Our objective was to reduce unintended extubations in the very low birthweight infant in a large delivery hospital to ≤2/100 ventilator days...
March 5, 2024: Journal of Neonatal-perinatal Medicine
https://read.qxmd.com/read/38443062/variation-in-prenatal-surveillance-and-management-of-anti-ssa-ro-autoantibody-positive-pregnancies
#14
JOURNAL ARTICLE
Lisa W Howley, Stephanie A Eyerly-Webb, Stacy A S Killen, Erin Paul, Anita Krishnan, Melanie R F Gropler, Bailey Drewes, Eric Dion, Amy Lund, Jill P Buyon, Bettina F Cuneo
OBJECTIVE: To describe international surveillance and treatment strategies for managing anti-SSA/Ro autoantibody positive pregnancies. STUDY DESIGN: An electronic REDCap questionnaire was distributed to Fetal Heart Society and North American Fetal Therapy Network members which queried institution-based risk stratification, surveillance methods/frequency, conduction abnormality treatments, and postnatal anti-SSA/Ro pregnancy assessment. RESULTS: 101 responses from 59 centers (59% US, 17% international) were collected...
December 2024: Journal of Maternal-fetal & Neonatal Medicine
https://read.qxmd.com/read/38442954/outcomes-following-the-adoption-of-standard-parenteral-nutrition-in-preterm-infants-a-whole-population-non-concurrent-control-study
#15
JOURNAL ARTICLE
Jessica Burgess-Shannon, Mohammad Chehrazi, Julia Lanoue, Neena Modi, Sabita N Uthaya
OBJECTIVE: To evaluate the impact of a quality improvement project of the adoption of standard parenteral nutrition (SPN) in preterm infants. DESIGN: Retrospective, multicentre, whole-population, non-concurrent control study using data from the UK National Neonatal Research Database between 1 January 2014 and 31 December 2020. SETTING: Neonatal units in London UK organised by geographical network. PATIENTS: Preterm infants <31 weeks' gestation...
March 4, 2024: Archives of Disease in Childhood. Fetal and Neonatal Edition
https://read.qxmd.com/read/38407906/cost-of-care-for-newborns-with-neonatal-abstinence-syndrome-in-a-state-medicaid-program
#16
JOURNAL ARTICLE
Caroline Jenkins, Matthew Hudnall, Courtney Hanson, Dwight Lewis, Jason M Parton
IMPORTANCE: Neonatal abstinence syndrome (NAS) is a medical condition among neonates experiencing substance withdrawal due to the mother's substance use during pregnancy. While previous studies suggest that the overall incidence and annual costs of NAS are increasing, to date, the long-term costs have yet to be demonstrated in Medicaid populations. OBJECTIVE: To examine the demographic differences and long-term costs of care for neonates diagnosed with vs not diagnosed with NAS...
February 5, 2024: JAMA Network Open
https://read.qxmd.com/read/38401787/process-and-outcome-measures-for-moderate-and-late-preterm-infants-in-tertiary-canadian-neonatal-intensive-care-units
#17
JOURNAL ARTICLE
Ayman Abou Mehrem, Jennifer Toye, Marc Beltempo, Khalid Aziz, Victoria Bizgu, Jonathan Wong, Nalini Singhal, Prakesh S Shah
OBJECTIVE: To describe the prevalence of and between-center variations in care practices and clinical outcomes of moderate and late preterm infants (MLPI) admitted to tertiary Canadian neonatal intensive care units (NICUs). STUDY DESIGN: A retrospective cohort study including infants born at 320/7 through 366/7 weeks' gestation and admitted to 25 NICUs participating in the Canadian Neonatal Network between 2015 and 2020. Patient characteristics, process measures represented by care practices, and outcome measures represented by clinical in-hospital and discharge outcomes were reported by gestational age weeks...
February 22, 2024: Journal of Pediatrics
https://read.qxmd.com/read/38372998/effect-of-maternal-and-newborn-care-service-package-on-perinatal-and-newborn-mortality-a-cluster-randomized-clinical-trial
#18
JOURNAL ARTICLE
Shabina Ariff, Uswa Jiwani, Arjumand Rizvi, Sajid Muhammad, Amjad Hussain, Imran Ahmed, Masawar Hussain, Muhammad Usman, Junaid Iqbal, Zahid Memon, Sajid Bashir Soofi, Zulfiqar A Bhutta
IMPORTANCE: In resource-constrained settings where the neonatal mortality rate (NMR) is high due to preventable causes and health systems are underused, community-based interventions can increase newborn survival by improving health care practices. OBJECTIVES: To develop and evaluate the effectiveness of a community-based maternal and newborn care services package to reduce perinatal and neonatal mortality in rural Pakistan. DESIGN, SETTING, AND PARTICIPANTS: This cluster randomized clinical trial was conducted between November 1, 2012, and December 31, 2013, in district Rahim Yar Khan in the province of Punjab...
February 5, 2024: JAMA Network Open
https://read.qxmd.com/read/38368328/knowledge-translation-strategies-used-for-sustainability-of-an-evidence-based-intervention-in-child-health-a-multimethod-qualitative-study
#19
JOURNAL ARTICLE
Christine E Cassidy, Rachel Flynn, Alyson Campbell, Lauren Dobson, Jodi Langley, Deborah McNeil, Ella Milne, Pilar Zanoni, Megan Churchill, Karen M Benzies
BACKGROUND: Sustainability of evidence-based interventions (EBIs) is suboptimal in healthcare. Evidence on how knowledge translation (KT) strategies are used for the sustainability of EBIs in practice is lacking. This study examined what and how KT strategies were used to facilitate the sustainability of Alberta Family Integrated Care (FICare)™, a psychoeducational model of care scaled and spread across 14 neonatal intensive care units, in Alberta, Canada. METHODS: First, we conducted an environmental scan of relevant documents to determine the use of KT strategies to support the sustainability of Alberta FICare™...
February 17, 2024: BMC Nursing
https://read.qxmd.com/read/38365210/-perinatal-networks-ensuring-regional-care-of-pregnant-woman-and-newborns
#20
JOURNAL ARTICLE
Mario Rüdiger, Jörg Reichert, Jochen Schmitt, Cahit Birdir
Health care of pregnant women and their newborns is facing major challenges due to the decline in birth rate and shortage of specialists. In the current discussion about future concepts, the centralization associated with minimum quantities and the necessary safeguarding of care in the area are often construed as conflicting goals. Instead, concepts are needed to guarantee that pregnant women and their children will continue to receive care close to home. The example of the saxony center for feto/neonatal health is used to show how partners in a region can jointly ensure care during pregnancy, birth and the neonatal period on a supra-local and cross-hospital basis...
February 16, 2024: Zeitschrift Für Geburtshilfe und Neonatologie
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