Zhi-Yuan Li, Yan Huang, Yan-Ting Yang, Dan Zhang, Yan Zhao, Jue Hong, Jie Liu, Li-Jie Wu, Cui-Hong Zhang, Huan-Gan Wu, Ji Zhang, Xiao-Peng Ma
AIM: To investigate the effects of herb-partitioned moxibustion (HPM) on phosphorylation of mitogen-activated extracellular signal-regulated kinase (MEK)1, extracellular signal-regulated kinase (ERK)1/2 and cAMP response element binding protein (CREB) in spinal cord of rats with chronic inflammatory visceral pain (CIVP), and to explore the central mechanism of HPM in treating CIVP. METHODS: Male Sprague-Dawley rats were randomized into normal, model, HPM, sham-HPM, MEK-inhibitor and dimethyl sulfoxide (DMSO) groups...
September 14, 2017: World Journal of Gastroenterology: WJG