keyword
MENU ▼
Read by QxMD icon Read
search

apnea effects

keyword
https://www.readbyqxmd.com/read/29232379/comparison-of-nalbuphine-and-sufentanil-for-colonoscopy-a-randomized-controlled-trial
#1
Chaoyi Deng, Xiao Wang, Qianmei Zhu, Yanming Kang, Jinlin Yang, Heng Wang
OBJECTIVES: Nalbuphine is as effective as morphine as a perioperative analgesic but has not been compared directly with sufentanil in clinical trials. The aims of this study were to compare the efficacy and safety of nalbuphine with that of sufentanil in patients undergoing colonoscopy and to determine the optimal doses of nalbuphine in this indication. METHODS: Two hundred and forty consecutive eligible patients aged 18-65 years with an American Society of Anesthesiologists classification of I-II and scheduled for colonoscopy were randomly allocated to receive sufentanil 0...
2017: PloS One
https://www.readbyqxmd.com/read/29229259/effects-of-positive-airway-pressure-and-mechanical-ventilation-of-the-lungs-during-cardiopulmonary-bypass-on-pulmonary-adverse-events-after-cardiac-surgery-a-systematic-review-and-meta-analysis
#2
Yi-Chia Wang, Chi-Hsiang Huang, Yu-Kang Tu
OBJECTIVE: To investigate whether different ventilation strategies during cardiopulmonary bypass (CPB) can improve outcomes in adult cardiac surgery patients. DESIGN: Systematic review of randomized controlled trials with meta-analyses. SETTING: Clinical trials for human studies up to July 2016 were obtained from electronic databases (Medline, Embase, PubMed, and the Cochrane Central Register of Controlled Trials) and reference lists of relevant randomized trials and review articles...
September 14, 2017: Journal of Cardiothoracic and Vascular Anesthesia
https://www.readbyqxmd.com/read/29228345/mechanisms-and-mediators-of-hypertension-induced-by-erythropoietin-and-related-molecules
#3
Rajiv Agarwal
Hypertension is a common but frequently overlooked adverse effect of erythropoietin (EPO) therapy. Underreporting of hypertension with EPO is likely due to either more aggressively managing hypertension through the prescription of antihypertensive drugs or closer attention to dry weight. The purpose and focus of this review is to critically evaluate the mechanisms of EPO-induced hypertension. Preclinical data are considered first, followed by clinical data where available. Mediated by a variety of molecules, there is an imbalance in the vascular tone favoring net vasoconstriction that mediates EPO-induced hypertension...
December 8, 2017: Nephrology, Dialysis, Transplantation
https://www.readbyqxmd.com/read/29227187/laparoscopic-sleeve-gastrectomy-endoscopic-findings-and-gastroesophageal-reflux-symptoms-at-18-month-follow-up
#4
Germán Viscido, Verónica Gorodner, Franco Signorini, Luciano Navarro, Lucio Obeide, Federico Moser
INTRODUCTION: Laparoscopic sleeve gastrectomy (LSG) has shown excellent results in terms of weight loss and resolution of comorbidities. Despite that, the effect of LSG on gastroesophageal reflux disease (GERD) is still a controversial topic. Our objective was to evaluate the presence of gastroesophageal reflux symptoms, erosive esophagitis (EE), and hiatal hernia (HH) in obese patients undergoing LSG. METHODS: Prospective observational study. LSG patients were studied before and at 18-month follow-up...
December 11, 2017: Journal of Laparoendoscopic & Advanced Surgical Techniques. Part A
https://www.readbyqxmd.com/read/29225775/fibromax-based-nonalcoholic-fatty-liver-disease-in-chronic-obstructive-pulmonary-disease-patients-with-obstructive-sleep-apnea-methodological-considerations
#5
Denis Monneret
The relationship between nonalcoholic fatty liver disease (NAFLD) and obstructive sleep apnea (OSA) has been well demonstrated, but remains to be evidenced in chronic obstructive pulmonary disease (COPD). Recently, Viglino et al. (Eur Respir J, 2017) attempted to determine the prevalence of liver fibrosis, steatosis and nonalcoholic steatohepatitis (NASH) in COPD patients, some of whom had OSA, basing the NAFLD diagnostic on three circulating biomarker-based liver scores: the FibroTest, SteatoTest and NashTest, from the Fibromax® panel...
2017: F1000Research
https://www.readbyqxmd.com/read/29224971/biomechanical-effects-of-a-mandibular-advancement-device-on-the-temporomandibular-joint
#6
David S P Heidsieck, Jan Harm Koolstra, Maurits H T de Ruiter, Aarnoud Hoekema, Jan de Lange
PURPOSE: Mandibular advancement devices are commonly used in the treatment of patients with mild to moderate obstructive sleep apnea (OSA). Designed to maintain the mandible in forced protrusion while being worn, mandibular advancement devices (MADs) are intended to increase the upper airway during sleep, thereby reducing OSA symptoms. Depending on the extent of mandibular protrusion, side effects including temporomandibular joint dysfunction are frequently reported. These are likely to reduce overall treatment success by affecting therapeutic adherence...
November 22, 2017: Journal of Cranio-maxillo-facial Surgery
https://www.readbyqxmd.com/read/29224135/serum-ferritin-and-obstructive-sleep-apnea-epidemiological-study
#7
Elin H Thorarinsdottir, Erna S Arnardottir, Bryndis Benediktsdottir, Christer Janson, Isleifur Olafsson, Allan I Pack, Thorarinn Gislason, Brendan T Keenan
PURPOSE: Ferritin is an intracellular iron storage protein and a marker of inflammation. Studies have shown that subjects with obstructive sleep apnea (OSA) have higher levels of circulating pro-inflammatory cytokines, but little is known about the association between ferritin and OSA. The aims of the study were to evaluate serum ferritin (S-Ferritin) levels in OSA patients compared to levels in the general population and also examine the effect of obesity level and treatment with positive airway pressure (PAP) on S-Ferritin levels...
December 9, 2017: Sleep & Breathing, Schlaf & Atmung
https://www.readbyqxmd.com/read/29224042/association-between-continuous-positive-airway-pressure-and-serum-aminotransferases-in-patients-with-obstructive-sleep-apnea
#8
Li-Da Chen, Liang-Ji Zhang, Xue-Jun Lin, Jia-Chao Qi, Hao Li, Zhi Wu, Qiao-Zhen Xu, Ya-Ping Huang, Li Lin
INTRODUCTION: Obstructive sleep apnea (OSA) has been suggested to be a potential contributing factor for nonalcoholic fatty liver disease (NAFLD). Studies on the association between continuous positive airway pressure (CPAP) and NAFLD in OSA patients are limited and controversial. OBJECTIVES: The aim of this study was to assess the relationship between OSA and NAFLD and the effect of CPAP therapy on serum aminotransferase levels in OSA patients. METHODS: A total of 160 consecutive patients who underwent standard polysomnography were enrolled...
December 9, 2017: European Archives of Oto-rhino-laryngology
https://www.readbyqxmd.com/read/29223509/neuropeptides-and-breathing-in-health-and-disease
#9
REVIEW
Katarzyna Kaczyńska, Dominika Zając, Piotr Wojciechowski, Ewelina Kogut, Małgorzata Szereda-Przestaszewska
Regulatory neuropeptides control and regulate breathing in physiological and pathophysiological conditions. While they have been identified in the neurons of major respiratory areas, they can be active not only at the central level, but also at the periphery via chemoreceptors, vagal afferents, or locally within lungs and airways. Some neuropeptides, such as leptin or substance P, are respiratory stimulants; others, such as neurotensin, produce variable effects on respiration depending on the site of application...
December 6, 2017: Pulmonary Pharmacology & Therapeutics
https://www.readbyqxmd.com/read/29222619/improvement-in-obstructive-sleep-apnea-after-a-tailored-behavioural-sleep%C3%A2-medicine-intervention-targeting-healthy-eating-and-physical-activity-a-randomised-controlled-trial
#10
Helena Igelström, Pernilla Åsenlöf, Margareta Emtner, Eva Lindberg
PURPOSE: The aim of the present single-centre randomised controlled trial was to assess the effect of a behavioural sleep medicine (BSM) intervention on obstructive sleep apnea (OSA) severity in patients who have been referred for new treatment with continuous positive airway pressure (CPAP). METHODS: After baseline assessment including ventilatory and anthropometric parameters, and physical activity monitoring, 86 patients who were overweight (BMI ≥ 25) and had moderate-severe OSA with apnea-hypopnea index (AHI) ≥ 15 were randomised into a control group (CG; CPAP and advice about weight loss) or an experimental group (ExpG; CPAP and BSM intervention targeting physical activity and eating behaviour)...
December 8, 2017: Sleep & Breathing, Schlaf & Atmung
https://www.readbyqxmd.com/read/29221483/the-role-of-sleepiness-on-arterial-stiffness-improvement-after-cpap-therapy-in-males-with-obstructive-sleep-apnea-a-prospective-cohort-study
#11
Maria Alexandra Mineiro, Pedro Marques da Silva, Marta Alves, Ana Luísa Papoila, Maria João Marques Gomes, João Cardoso
BACKGROUND: Obstructive sleep apnea (OSA) is associated with increased cardiovascular risk. This study aim to assess differences in changes in arterial stiffness of two groups of patients, defined as having daytime sleepiness or not, after continuous positive airway pressure (CPAP) treatment. METHODS: A selected cohort of consecutive male patients, under 65 years old, with moderate to severe OSA and without great number of comorbidities was studied. The diagnosis was confirmed by home respiratory poligraphy...
December 8, 2017: BMC Pulmonary Medicine
https://www.readbyqxmd.com/read/29217205/increased-urinary-erythropoietin-excretion-in-severe-sleep-apnea-hipoapnea-syndrome-the-effect-of-cpap
#12
Miquel Félez, Nuria Grau, Antonia Ruiz, Encarna Guardiola, Carles Sanjuas, Cristina Estirado, Maribel Navarro-Muñoz, Antoni Pascual, Mauricio Orozco-Levi, Joaquim Gea
INTRODUCTION: Tissue hypoxia stimulates the production of erythropoietin (EPO), the main effect of which is, in turn, to stimulate erythropoiesis. Sleep apnea-hypopnea syndrome (SAHS) is an entity characterized by repeated episodes of hypoxemia during sleep. OBJECTIVE: To analyze whether hypoxemia stimulated increased urinary excretion of EPO, and if so, to evaluate if treatment with continuous positive airway pressure (CPAP) can inhibit this phenomenon. METHODS: We studied 25 subjects with suspected SAHS who underwent a polysomnography study (PSG)...
December 4, 2017: Archivos de Bronconeumología
https://www.readbyqxmd.com/read/29215742/effects-of-small-interfering-rna-targeting-tlr4-on-expressions-of-adipocytokines-in-obstructive-sleep-apnea-hyponea-syndrome-with-hypertension-in-a-rat-model
#13
Jing-Guo Wu, Nan Xun, Li-Jin Zeng, Zhen-Yu Li, Yan-Bing Liang, Hao Tang, Zhong-Fu Ma
We explored the effects of RNA interference-mediated silencing of TLR4 gene on expressions of adipocytokines in obstructive sleep apnea hyponea syndrome (OSAS) with hypertension in a rat model. Systolic blood pressure of caudal artery and physiological changes were observed when establishing rat models of OSAS with hypertension. Mature rat adipocytes were induced from separated and cultured primary rat adipocytes. To transfect rat mature adipocytes, TLR4 siRNA group and negative control (NC) siRNA group were established...
December 7, 2017: Journal of Cellular Physiology
https://www.readbyqxmd.com/read/29214378/the-effectiveness-of-two-types-of-mads-for-osa-therapy
#14
Francis Emma Verburg, Klara Hilda Alphonsine Bollen, Henk-Jan Donker, Gerbrand Johannes Cornelis Kramer
OBJECTIVES: The purpose of this study was to determine differences in effectiveness between two types of mandibular advancement device (MAD). MATERIAL AND METHODS: In this retrospective, cohort study, the two devices used were MAD type "Somnodent-Flex" (MAD 1) and MAD type "Herbst" (MAD 2). One hundred thirty-seven patients participated in this study, 67 patients were treated with MAD 1, and 70 patients with MAD 2. The indication MAD with obstructive sleep apnea (OSA) is based on a polysomnography test, in accordance with the CBO guidelines...
December 6, 2017: Clinical Oral Investigations
https://www.readbyqxmd.com/read/29214337/sleep-disordered-breathing-in-patients-with-sickle-cell-disease
#15
REVIEW
Vikram M Raghunathan, Peter L Whitesell, Seah H Lim
Sickle cell disease is one of the most common hereditary hemoglobinopathies worldwide, and its vaso-occlusive and hemolytic crises cause considerable patient morbidity. A growing body of evidence has shown that sleep-disordered breathing, and in particular, obstructive sleep apnea, occurs at high frequency in the sickle cell population, and that there is significant overlap in the underlying pathophysiology of these two conditions. Through a variety of mechanisms including nocturnal hypoxemia and increased oxidative stress, production of pro-inflammatory cytokines, and endothelial dysfunction, sickle cell anemia and sleep-disordered breathing potentiate each other's clinical effects and end-organ complications...
December 6, 2017: Annals of Hematology
https://www.readbyqxmd.com/read/29211505/the-effect-of-dietary-nitrate-on-nocturnal-sleep-disordered-breathing-and-arterial-oxygen-desaturation-at-high-altitude
#16
Alexander Patrician, Harald Engan, David Lundsten, Ludger Grote, Helena Vigetun-Haughey, Erika Schagatay
Patrician, Alexander, Harald Engan, David Lundsten, Ludger Grote, Helena Vigetun-Haughey, and Erika Schagatay. The effect of dietary nitrate on nocturnal sleep-disordered breathing and arterial oxygen desaturation at high altitude. High Alt Med Biol 00:000-000, 2017.-Sleep-disordered breathing and fluctuations in arterial oxygen saturation (SaO2) are common during sleep among lowlanders ascending to high altitude. Dietary nitrate (NO3-) supplementation has been shown to lower the O2 consumption in various conditions...
December 6, 2017: High Altitude Medicine & Biology
https://www.readbyqxmd.com/read/29211322/perivascular-adipose-tissue-and-the-dynamic-regulation-of-kv-7-and-kir-channels-implications-to-resistant-hypertension
#17
Maik Gollasch, Donald G Welsh, Rudolf Schubert
Resistant hypertension is defined as high blood pressure that remains uncontrolled despite treatment with at least three antihypertensive drugs at adequate doses. Resistant hypertension is an increasingly common clinical problem in older age, obesity, diabetes, sleep apnea, and chronic kidney disease. Although the direct vasodilator minoxidil was introduced in the early 1970s, only recently has this drug been shown to be particularly effective in a subgroup of patients with treatment-resistant or uncontrolled hypertension...
December 6, 2017: Microcirculation: the Official Journal of the Microcirculatory Society, Inc
https://www.readbyqxmd.com/read/29208758/respiratory-volume-monitoring-reduces-hypoventilation-and-apnea-in-subjects-undergoing-procedural-sedation
#18
Robert H Nichols, Justin A Blinn, Thuan M Ho, Robert A McQuitty, Michael P Kinsky
INTRODUCTION: The use of monitored anesthesia care for endoscopic procedures increases the risk of respiratory depression, necessitating careful monitoring of patient ventilation. We examined the effectiveness of an impedance-based respiratory volume monitor (RVM) in improving the safety of patients undergoing upper and lower gastrointestinal endoscopies under total intravenous anesthesia. We hypothesized that feedback from the RVM would allow anesthesiologists to maintain adequate ventilation, which would reduce the duration of respiratory depression (ie, hypoventilation and apnea) compared to a blinded control group...
December 5, 2017: Respiratory Care
https://www.readbyqxmd.com/read/29208538/sleep-related-painful-erections-a-meta-analysis-on-the-pathophysiology-and-risks-and-benefits-of-medical-treatments
#19
REVIEW
Sanne Vreugdenhil, Alida Cornelia Weidenaar, Igle Jan de Jong, Mels Frank van Driel
BACKGROUND: Patients with sleep-related painful erections (SRPEs) have frequent awakenings from deep penile pain during nocturnal erections. This results in severe sleep deprivation. AIM: To review the current literature on SRPEs and discuss the pathophysiologic theories and risks and benefits of medical treatments. METHODS: PubMed was searched using the terms sleep-related painful erections, nocturnal priapism, treatment, and sleep-related erections...
December 2, 2017: Journal of Sexual Medicine
https://www.readbyqxmd.com/read/29204589/hyoid-myotomy-and-suspension-without-simultaneous-palate-or-tongue-base-surgery%C3%A2-for-obstructive-sleep-apnea
#20
Adrian A Ong, Jonathan Buttram, Shaun A Nguyen, Dustin Platter, Michael R Abidin, M Boyd Gillespie
Objective: Determine the effects of hyoid myotomy and suspension (HMS) without concurrent palatal or tongue base sleep surgery for obstructive sleep apnea (OSA). Method: Patients with OSA treated with HMS were identified using CPT code (21685) at an academic and private sleep surgery clinic. Those who underwent concurrent palatal or tongue base sleep surgery were excluded. Outcomes included simultaneous procedures, apnea-hypopnea index (AHI), lowest oxyhemoglobin saturation (LSAT), and Epworth Sleepiness Scale (ESS)...
June 2017: World Journal of Otorhinolaryngology—Head and Neck Surgery
keyword
keyword
83190
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"