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https://www.readbyqxmd.com/read/28097412/acute-pancreatitis-after-percutaneous-biliary-drainage-an-obstacle-in-liver-surgery-for-proximal-biliary-cancer
#1
Nadia Russolillo, Andrea Massobrio, Serena Langella, Roberto Lo Tesoriere, Paolo Carbonatto, Alessandro Ferrero
BACKGROUND: Percutaneous transhepatic biliary drainage (PTBD) has a crucial role in treatment of proximal biliary cancer (PBC). We assessed the incidence, risk factors, and impact of acute pancreatitis (AP) post-PTBD. METHODS: Forty patients with PBC scheduled for PTBD from January 2005 to December 2015 were enrolled. Exclusion criteria were missing clinical data, PTBD performed in other institutions, and palliative PTBD. RESULT: The 40 patients comprised 8 (20%) with gallbladder cancer, 6 (15%) with intrahepatic cholangiocarcinoma, and 26 (65%) with perihilar cholangiocarcinoma...
January 17, 2017: World Journal of Surgery
https://www.readbyqxmd.com/read/28094209/simplified-low-dose-rate-infant-total-body-irradiation
#2
Nels Knutson, Y James Rao, Sridhar Yaddanapudi, Stephanie M Perkins, H Harold Li
PURPOSE: Low-dose-rate total body irradiation (LDR TBI) in infants possesses unique challenges because of the setup limitations imposed by anesthesia. We present an LDR TBI method with an anteroposterior/posteroanterior arrangement and dose rate < 10 cGy/minute for infants (thickness <14 cm) without the use of a beam attenuator. MATERIALS AND METHODS: The delivery used a 6 MV TrueBeam linear accelerator (Varian Medical Systems, Palo Alto, CA) with adjustable meterset rates below 100 MU/minute...
October 24, 2016: Practical Radiation Oncology
https://www.readbyqxmd.com/read/28093642/the-ethical-framework-for-performing-research-with-rare-inherited-neurometabolic-disease-patients
#3
Viviana Giannuzzi, Hugo Devlieger, Lucia Margari, Viveca Lena Odlind, Lamis Ragab, Cinzia Maria Bellettato, Francesca D'Avanzo, Christina Lampe, Linda Cassis, Elisenda Cortès-Saladelafont, Ángels Garcia Cazorla, Ivo Barić, Ljerka Cvitanović-Šojat, Ksenija Fumić, Christine I Dali, Franco Bartoloni, Fedele Bonifazi, Maurizio Scarpa, Adriana Ceci
: The need for performing clinical trials to develop well-studied and appropriate medicines for inherited neurometabolic disease patients faces ethical concerns mainly raising from four aspects: the diseases are rare; include young and very young patients; the neurological impairment may compromise the capability to provide 'consent'; and the genetic nature of the disease leads to further ethical implications. This work is intended to identify the ethical provisions applicable to clinical research involving these patients and to evaluate if these cover the ethical issues...
January 16, 2017: European Journal of Pediatrics
https://www.readbyqxmd.com/read/28090162/systemic-market-and-organizational-changes-impact-on-p-t-committees
#4
F Randy Vogenberg, Rita Marcoux, Martha M Rumore
The authors consider market stakeholder consolidation, market-driven efficiency demands, consumerism, and legal enforcement of patient rights related to access to appropriate drugs and posit how future P&T committees may approach these issues.
January 2017: P & T: a Peer-reviewed Journal for Formulary Management
https://www.readbyqxmd.com/read/28062971/cost-equivalence-and-pluralism-in-publicly-funded-health-care-systems
#5
Dominic Wilkinson, Julian Savulescu
Clinical guidelines summarise available evidence on medical treatment, and provide recommendations about the most effective and cost-effective options for patients with a given condition. However, sometimes patients do not desire the best available treatment. Should doctors in a publicly-funded healthcare system ever provide sub-optimal medical treatment? On one view, it would be wrong to do so, since this would violate the ethical principle of beneficence, and predictably lead to harm for patients. It would also, potentially, be a misuse of finite health resources...
January 6, 2017: Health Care Analysis: HCA: Journal of Health Philosophy and Policy
https://www.readbyqxmd.com/read/28056665/the-patient-perspective-on-the-effects-of-medical-record-accessibility-a-systematic-review
#6
Peter Vermeir, Sophie Degroote, Dominique Vandijck, Hanne Van Tiggelen, Renaat Peleman, Rik Verhaeghe, An Mariman, Dirk Vogelaers
BACKGROUND: Health care is shifting from a paternalistic to a participatory model, with increasing patient involvement. Medical record accessibility to patients may contribute significantly to patient comanagement. OBJECTIVES: To systematically review the literature on the patient perspective of effects of personal medical record accessibility on the individual patient, patient-physician relationship and quality of medical care. METHODS: Screening of PubMed, Web of Science, Cinahl, and Cochrane Library on the keywords 'medical record', 'patient record', 'communication', 'patient participation', 'doctor-patient relationship', 'physician-patient relationship' between 1 January 2002 and 31 January 2016; systematic review after assessment for methodological quality...
January 6, 2017: Acta Clinica Belgica
https://www.readbyqxmd.com/read/28050977/influence-of-age-on-factors-associated-with-peri-implant-bone-loss-after-prosthetic-rehabilitation-over-osseointegrated-implants
#7
Rejane El Pedro, João P De Carli, Maria Ss Linden, Igor Fp Lima, Luiz R Paranhos, Max D Costa, Ângelo Jg Bós
INTRODUCTION: To verify the influence of age on factors associated with peri-implant bone loss after prosthetic rehabilitation over osseointegrated implants. MATERIALS AND METHODS: This is an analytical, observational, and longitudinal study with initial 23 participants. Patients presenting with osseointegrated implants with their respective prostheses installed were included, and they could be carriers of chronic and degenerative diseases, such as diabetes, osteoporosis, hypothyroidism, cardiovascular disease (CVD), and systemic arterial hypertension...
January 1, 2017: Journal of Contemporary Dental Practice
https://www.readbyqxmd.com/read/28041869/-palliative-care-after-neonatal-intensive-care-contributions-of-leonetti-law-and-remaining-challenges
#8
P Kuhn, L Dillenseger, N Cojean, B Escande, C Zores, D Astruc
The 2005 enactment of the "Patients' rights and end-of-life care" act, known as the Leonetti law, has been accompanied by practical changes in the processes of withdrawal and withholding of active life-sustaining treatments. This law has also promoted the implementation of palliative care in perinatal medicine to avoid unreasonable therapeutic interventions and to preserve the dying patient's quality of life and human dignity. Recently, a new law has been voted by the French National Assembly and new reflections on the ethical aspects of the end of life in neonatal medicine should resume again within the French Society of Neonatology in the working group on ethical issues in neonatology...
December 29, 2016: Archives de Pédiatrie: Organe Officiel de la Sociéte Française de Pédiatrie
https://www.readbyqxmd.com/read/28040825/training-patients-with-schizophrenia-to-share-decisions-with-their-psychiatrists-a-randomized-controlled-trial
#9
Johannes Hamann, Anna Parchmann, Nina Sassenberg, Katharina Bronner, Margot Albus, Alwin Richter, Sandra Hoppstock, Werner Kissling
PURPOSE: Many patients with schizophrenia have a desire for shared decision-making (SDM). However, in clinical practice SDM often does not take place. One cause might be that many patients behave passively in the medical encounter, therefore not facilitating SDM. It was the aim of the study to evaluate the effects of a patient directed SDM-training on patients' communicative behavior in the consultation, their attitudes towards decision-making and their long-term adherence. METHODS: Randomized-controlled trial comparing a five-session SDM-training for inpatients with schizophrenia with five sessions of non-specific group training...
December 31, 2016: Social Psychiatry and Psychiatric Epidemiology
https://www.readbyqxmd.com/read/28039684/patients-bill-of-rights-and-effective-factors-of-workplace-violence-against-female-nurses-on-duty-at-ilam-teaching-hospitals
#10
Ali-Ashraf Aivazi, Waleyeh Menati, Hamed Tavan, Sasan Navkhasi, Abuzar Mehrdadi
BACKGROUND: Workplace violence against female nurses is an increasing problem. In addition, recognition the rights of patients can reduce such violence against female nurses. Therefore, the aim of the current study was to investigate workplace violence against female nurses in respect with patients' bill of rights at two public hospitals of Ilam in 2012. METHODS: In a descriptive cross-sectional research, workplace violence against female nurses was studied. Data were gathered employing a researcher made questionnaire filled out by 106 female nurses...
January 1, 2017: Journal of Injury & Violence Research
https://www.readbyqxmd.com/read/28038803/neu3-sialidase-role-in-activating-hif-1%C3%AE-in-response-to-chronic-hypoxia-in-cyanotic-congenital-heart-patients
#11
Marco Piccoli, Erika Conforti, Alessandro Varrica, Andrea Ghiroldi, Federica Cirillo, Giulia Resmini, Francesca Pluchinotta, Guido Tettamanti, Alessandro Giamberti, Alessandro Frigiola, Luigi Anastasia
BACKGROUND: Hypoxia is a common feature of many congenital heart defects (CHDs) and significantly contributes to their pathophysiology. Thus, understanding the mechanism underlying cell response to hypoxia is vital for the development of novel therapeutic strategies. Certainly, the hypoxia inducible factor (HIF) has been extensively investigated and it is now recognized as the master regulator of cell defense machinery counteracting hypoxic stress. Along this line, we recently discovered and reported a novel mechanism of HIF activation, which is mediated by sialidase NEU3...
December 21, 2016: International Journal of Cardiology
https://www.readbyqxmd.com/read/28031549/clinicopathological-features-and-prognosis-of-hepatic-epithelioid-hemangioendothelioma-after-liver-resection-and-transplantation
#12
Dong-Hwan Jung, Shin Hwang, Seung-Mo Hong, Ki-Hun Kim, Young-Joo Lee, Chul-Soo Ahn, Deok-Bog Moon, Tae-Yong Ha, Gi-Won Song, Gil-Chun Park, Eunsil Yu, Sung-Gyu Lee
BACKGROUND Epithelioid hemangioendothelioma (EHE) is a rare vascular tumor. We present a single-center study on hepatic EHE cases treated by hepatic resection (HR) or liver transplantation (LT). MATERIAL AND METHODS Six HR patients with hepatic EHE were identified during 5 years from 2010 to 2014; EHE represented 0.13% (6 of 4572) of all primary liver tumors. Two LT recipients were also identified during 12 years from 2003 to 2014, who represented 0.06% (2 of 3576) of all adult LT patients. RESULTS Mean age of the patients was 42...
December 29, 2016: Annals of Transplantation: Quarterly of the Polish Transplantation Society
https://www.readbyqxmd.com/read/28028257/-effectiveness-of-dexrazoxane-for-extravasation-of-anthracycline-antitumor-antibiotics-reporting-measures-developed-against-extravasation-in-the-hospital
#13
Satoshi Kawamoto, Takuya Shirahata, Tetsuya Katori, Takafumi Izumo, Hitomi Kadono, Hiroaki Fujita, Rumiko Okamoto
Dexrazoxane(DXZ)is a drug used for treating extravasation(EV)of anthracycline antitumor antibiotics based on 2 of its mechanisms of action through Topo II. In Japan, it has been used in approximately 150 patients as of January 2016, but there is no detailed report. Three DXZ treatments were carried out for 2 cases in our facilities. One case involved a patient's right forearm while 2 cases occurred involved the left and right forearms of each of the patients, and both were Grade 2(CTCAE v4.0). The EV healed in all cases, and surgical procedures were not needed...
December 2016: Gan to Kagaku Ryoho. Cancer & Chemotherapy
https://www.readbyqxmd.com/read/28026854/investigations-on-renal-vascularisation-pathology-in-the-polish-population-1-incidence-of-multiple-kidney-arteries
#14
Henryk H Sośnik, Katarzyna Sośnik
BACKGROUND: The aim of the study was to determine the incidence of multiple kidney arteries in the Polish population. MATERIAL AND METHODS: The study group comprised 924 deceased patients aged between one month and 94 years (mean age : 63.4 ± 22.4 years) who were subject to aortonephrography and sample preparation. The ratio of male to female patients was 479:445. RESULTS: Multiple kidney arteries were observed in 44.8% male and 31.5% female patients (p=0,004)...
December 27, 2016: Folia Morphologica (Warsz)
https://www.readbyqxmd.com/read/28012333/a-case-report-of-small-bowel-obstruction-from-previously-undiagnosed-lobular-breast-carcinoma-first-in-australian-literature
#15
Adam Thomas Cristaudo, Katherine Jing Zhu
INTRODUCTION: This case report is the first in the Australian literature of a patient, without prior diagnosis, presenting with a bowel obstruction secondary to lobular breast cancer. This highlights a relatively rare cause of bowel obstruction, but also the importance of breast self-examination as a compliment to the current BreastScreen Australia program. PRESENTATION OF CASE: A 67-year-old female presented to the Emergency Department with a 48-h history of sharp, constant epigastric pain, vomiting and constipation...
November 30, 2016: International Journal of Surgery Case Reports
https://www.readbyqxmd.com/read/28008610/medicolegal-implications-of-nosocomial-infections-a-case-report-of-aspergillus-contamination-during-cardiac-surgery
#16
Lucile Tuchtan, Marie-Dominique Piercecchi-Marti, Henri Dumon, Dominique Métras, Georges Léonetti, Christophe Bartoli
Nosocomial infections have become a major issue of public health and lead to an increasing number of suits for damages. We present a rare case of Aspergillus contamination during cardiac surgery, describe the medicolegal investigation, and present the new system for compensation of bodily injury after nosocomial infection in France, based on the law of March 4, 2002 on patient rights and quality in the health system. This case demonstrates the limits of compensation for nosocomial infections on the grounds of national solidarity...
December 23, 2016: Journal of Forensic Sciences
https://www.readbyqxmd.com/read/28007511/-neonatal-palliative-care-at-home-contribution-of-the-regional-pediatric-palliative-care-team
#17
N Cojean, C Strub, P Kuhn, L Calvel
The "patients' rights and end-of-life care" act, known as the Leonetti law, has allowed implementation of palliative care in neonatology as an alternative to unreasonable therapeutic interventions. A palliative care project can be offered to newborns suffering from intractable diseases. It must be focused on the newborn's quality of life and comfort and on family support. Palliative care for newborns can be provided in the delivery room, in the neonatal unit, and also at home. Going home is possible but requires medical support...
December 19, 2016: Archives de Pédiatrie: Organe Officiel de la Sociéte Française de Pédiatrie
https://www.readbyqxmd.com/read/27995060/hippocampal-volume-predicts-antidepressant-efficacy-in-depressed-patients-without-incomplete-hippocampal-inversion
#18
Romain Colle, Claire Cury, Marie Chupin, Eric Deflesselle, Patrick Hardy, Ghaidaa Nasser, Bruno Falissard, Denis Ducreux, Olivier Colliot, Emmanuelle Corruble
BACKGROUND: Incomplete hippocampal inversion (IHI), also called malrotation, is a frequent atypical anatomical pattern of the hippocampus. Because of the crucial implication of the hippocampus in Major Depressive Disorder (MDD) and the neurodevelopmental hypothesis of MDD, we aimed to assess the prevalence of IHI in patients with MDD, the link of IHI with hippocampal volume (HV) and the impact of IHI on the predictive value of HV for response and remission after antidepressant treatment...
2016: NeuroImage: Clinical
https://www.readbyqxmd.com/read/27957310/evaluation-of-patients-rights-observance-according-to-patients-rights-charter-in-educational-hospitals-affiliated-to-mashhad-university-of-medical-sciences-medical-staffs-views
#19
Alireza Sabzevari, Mohammad Ali Kiani, Masumeh Saeidi, Seyed Ali Jafari, Hamidreza Kianifar, Hamid Ahanchian, Lida Jarahi, Mohsen Zakerian
INTRODUCTION: To supply quality services and healthcare, it is evident that medical ethics and patients' rights, while providing medical and healthcare services need to be observed. This study was conducted to evaluate observance of the Patients' Rights Charter among medical staff of educational hospitals affiliated to Mashhad University of Medical Sciences. METHODS: This cross-sectional study was conducted in four educational hospitals in Mashhad on eighty physicians, nurses, nurse aids and medical students...
October 2016: Electronic Physician
https://www.readbyqxmd.com/read/27934570/how-to-allow-conscientious-objection-in-medicine-while-protecting-patient-rights
#20
Aaron Ancell, Walter Sinnott-Armstrong
Paradigmatic cases of conscientious objection in medicine are those in which a physician refuses to provide a medical service or good because doing so would conflict with that physician's personal moral or religious beliefs. Should such refusals be allowed in medicine? We argue that (1) many conscientious objections to providing certain services must be allowed because they fall within the range of freedom that physicians have to determine which services to offer in their practices; (2) at least some conscientious objections to serving particular groups of patients should be allowed because they are not invidiously discriminatory; and (3) even in cases of invidiously discriminatory conscientious objections, legally prohibiting individual physicians from refusing to serve patients on the basis of such objections is not always the best solution...
January 2017: Cambridge Quarterly of Healthcare Ethics: CQ: the International Journal of Healthcare Ethics Committees
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