keyword
https://read.qxmd.com/read/38537174/preparation-of-antibacterial-biobased-fibers-by-triaxial-microfluidic-spinning-technology-using-ionic-liquids-as-the-solvents
#1
JOURNAL ARTICLE
Zhimin Zhao, Junlei Wang, Hanmeng Yuan, Jie Xu, Hongshuai Gao, Yi Nie
Bacterial infections have become a serious threat to public health. The utilization of antibacterial textiles offers an effective way to combat bacterial infections at the source, instead of relying solely on antibiotic consumption. Herein, efficient and durable antibacterial fibers based on quercetin and cellulose were prepared by a triaxial microfluidic spinning technology using ionic liquids (ILs) as the solvents. It was indicated that the structure and properties of the antibacterial fibers were affected by the type of IL and the flow rates during the triaxial microfluidic spinning process...
March 27, 2024: ACS Applied Materials & Interfaces
https://read.qxmd.com/read/38535782/duration-of-zearalenone-exposure-has-implications-on-health-parameters-of-lactating-cows
#2
JOURNAL ARTICLE
Raul Rivera-Chacon, Thomas Hartinger, Ezequias Castillo-Lopez, Claudia Lang, Felipe Penagos-Tabares, Rita Mühleder, Rana Muhammad Atif, Johannes Faas, Qendrim Zebeli, Sara Ricci
There is a limited research focus on evaluating the detrimental effects of prolonged zearalenone (ZEN) intake on dairy cows' health under controlled conditions. This experiment was conducted to evaluate whether the length of exposure to a ZEN-contaminated total mixed ration (TMR) at a level of 9.45 mg per day can negatively influence animal health parameters, such as milk composition, rumen and fecal fermentation, and the chewing activity of lactating dairy cows. For this experiment, we used 18 lactating Simmental cows that were fed a diet of 60% forage and 40% concentrate (on dry matter basis) for 26 consecutive days...
February 27, 2024: Toxins
https://read.qxmd.com/read/38526761/intraoperative-kidney-replacement-therapy-in-acute-liver-failure
#3
JOURNAL ARTICLE
Daniel Henderson, Anish Gupta, Shina Menon, Akash Deep
Paediatric acute liver failure (PALF) is often characterised by its rapidity of onset and potential for significant morbidity and even mortality. Patients often develop multiorgan dysfunction/failure, including severe acute kidney injury (AKI). Whilst the management of PALF focuses on complications of hepatic dysfunction, the associated kidney impairment can significantly affect patient outcomes. Severe AKI requiring continuous kidney replacement therapy (CKRT) is a common complication of both PALF and liver transplantation...
March 25, 2024: Pediatric Nephrology
https://read.qxmd.com/read/38496522/comprehensive-mapping-of-sensory-and-sympathetic-innervation-of-the-developing-kidney
#4
Pierre-Emmanuel Y N'Guetta, Sarah R McLarnon, Adrien Tassou, Matan Geron, Sepenta Shirvan, Rose Z Hill, Grégory Scherrer, Lori L O'Brien
The kidney functions as a finely tuned sensor to balance body fluid composition and filter out waste through complex coordinated mechanisms. This versatility requires tight neural control, with innervating efferent nerves playing a crucial role in regulating blood flow, glomerular filtration rate, water and sodium reabsorption, and renin release. In turn sensory afferents provide feedback to the central nervous system for the modulation of cardiovascular function. However, the cells targeted by sensory afferents and the physiological sensing mechanisms remain poorly characterized...
March 7, 2024: bioRxiv
https://read.qxmd.com/read/38487475/-in-vivo-measurement-of-pediatric-extracorporeal-oxygenator-insensible-losses-a-single-center-pilot-study
#5
JOURNAL ARTICLE
Tess L Suttles, John Poe, Tara M Neumayr, Ahmed S Said
INTRODUCTION: Fluid overload on Extracorporeal Membrane Oxygenation (ECMO) is associated with worse outcomes. Previous in vitro studies have attempted to quantify oxygenator-related insensible losses, as failure to account for this fluid loss may lead to inaccurate fluid balance assessment and potentially harmful clinical management, such as unnecessary exposure to diuretics, slow continuous ultrafiltration (SCUF), or continuous kidney replacement therapy (CKRT). We performed a novel in vivo study to measure insensible fluid losses in pediatric ECMO patients...
2024: Frontiers in Pediatrics
https://read.qxmd.com/read/38461669/beyond-the-cradle-amidst-microplastics-and-the-ongoing-peril-during-pregnancy-and-neonatal-stages-a-holistic-review
#6
REVIEW
Indrani Paul, Pritam Mondal, Dibyajyoti Haldar, Gopinath Halder
Advancements in research concerning the occurrence of microplastics (MPs) in human blood, sputum, urine, and breast milk samples have piqued the interest of the scientific community, prompting further investigation. MPs present in the placenta, amniotic fluid, and meconium raise concerns about interference with embryonic development, leading to preeclampsia, stillbirth, preterm birth, and spontaneous abortion. The challenges posed by MPs extend beyond pregnancy, affecting the digestive, reproductive, circulatory, immune, and central nervous systems...
March 6, 2024: Journal of Hazardous Materials
https://read.qxmd.com/read/38409366/long-term-health-outcomes-associated-with-hydration-status
#7
REVIEW
Natalia I Dmitrieva, Manfred Boehm, Paul H Yancey, Sofia Enhörning
Body water balance is determined by fundamental homeostatic mechanisms that maintain stable volume, osmolality and the composition of extracellular and intracellular fluids. Water balance is maintained by multiple mechanisms that continuously match water losses through urine, the skin, the gastrointestinal tract and respiration with water gains achieved through drinking, eating and metabolic water production. Hydration status is determined by the state of the water balance. Underhydration occurs when a decrease in body water availability, due to high losses or low gains, stimulates adaptive responses within the water balance network that are aimed at decreasing losses and increasing gains...
February 26, 2024: Nature Reviews. Nephrology
https://read.qxmd.com/read/38403003/the-rhizomes-of-atractylodes-macrocephala-koidz-improve-gastrointestinal-health-and-pregnancy-outcomes-in-pregnant-mice-via-modulating-intestinal-barrier-and-water-fluid-metabolism
#8
JOURNAL ARTICLE
Wang Chenxing, Su Jie, Tian Yajuan, Li Ting, Zhong Yuying, Chen Suhong, Lv Guiyuan
ETHNOPHARMACOLOGICAL RELEVANCE: Baizhu (BZ) is the dried rhizome of Atractylodes macrocephala Koidz (Compositae), which invigorates the spleen, improves vital energy, stabilizes the fetus, and is widely used for treating spleen deficiency syndrome. However, the impact of BZ on gastrointestinal function during pregnancy remains unexplored. AIM OF THE STUDY: This study elucidated the ameliorative effects of BZ on gastrointestinal health and pregnancy outcomes in pregnant mice with spleen deficiency diarrhea (SDD)...
February 24, 2024: Journal of Ethnopharmacology
https://read.qxmd.com/read/38402748/plasma-sodium-during-the-recovery-of-renal-function-in-critically-ill-adult-patients-multicenter-prospective-cohort-study
#9
JOURNAL ARTICLE
Natalia Alejandra Angeloni, Irene Outi, Monica Alejandra Alvarez, Sofia Sterman, Julio Fernandez Morales, Fabio Daniel Masevicius
BACKGROUND: Sodium increases during acute kidney injury (AKI) recovery. Both hypernatremia and positive fluid balances are associated with increased mortality. We aimed to evaluate the association between daily fluid balance and daily plasma sodium during the recovery from AKI among critical patients. METHODS: Adult patients with AKI were enrolled in four ICUs and followed up for four days or until ICU discharge or hemodialysis initiation. Day zero was the peak day of creatinine...
February 24, 2024: Journal of Critical Care
https://read.qxmd.com/read/38397582/green-solvents-for-extraction-of-natural-food-colorants-from-plants-selectivity-and-stability-issues
#10
REVIEW
Milena Tankova Tzanova, Zvezdelina Yaneva, Donika Ivanova, Monika Toneva, Neli Grozeva, Neli Memdueva
Consumers associate the color of food with its freshness and quality. More and more attention is being paid to natural colorants that bring additional health benefits to humans. Such natural substances are the carotenoids (yellow to orange), the anthocyanins (red to blue), and the betalains (red and yellow), which are very sensitive to exposure to light, air, high temperatures, and chemicals. Stability and diversity in terms of color can be optimized by using environmentally friendly and selective extraction processes that provide a balance between efficacy, safety, and stability of the resulting extracts...
February 16, 2024: Foods (Basel, Switzerland)
https://read.qxmd.com/read/38387416/flying-high-exploring-the-effect-of-red-bull-on-blood-pressure-after-microsurgical-breast-reconstruction-in-a-randomized-controlled-trial
#11
JOURNAL ARTICLE
Nicole E Speck, Kathrin Dreier, Andrin Fluetsch, Christina Ranacher, Doris Babst, Alessia M Lardi, Jian Farhadi
BACKGROUND: A sufficiently high blood pressure (BP) is essential for flap perfusion after microsurgical breast reconstruction. However, postoperative hypotension is common after these procedures. Perioperative volume overload may increase flap-related complications, and postoperative vasopressor use may be limited depending on institutions. Red Bull has been shown to increase BP in several studies. We aimed to evaluate the effect of Red Bull on perfusion-related variables after microsurgical breast reconstruction...
February 2, 2024: Journal of Plastic, Reconstructive & Aesthetic Surgery: JPRAS
https://read.qxmd.com/read/38385255/sodium-interstitium-lymphatics-and-hypertension-a-tale-of-hydraulics
#12
REVIEW
Giacomo Rossitto, Giovanni Bertoldi, Joseph M Rutkowski, Brett M Mitchell, Christian Delles
Blood pressure is regulated by vascular resistance and intravascular volume. However, exchanges of electrolytes and water between intra and extracellular spaces and filtration of fluid and solutes in the capillary beds blur the separation between intravascular, interstitial and intracellular compartments. Contemporary paradigms of microvascular exchange posit filtration of fluids and solutes along the whole capillary bed and a prominent role of lymphatic vessels, rather than its venous end, for their reabsorption...
April 2024: Hypertension
https://read.qxmd.com/read/38377974/fluid-balance-in-continuous-renal-replacement-therapy-prescribing-delivering-and-review
#13
REVIEW
Ian Charles Baldwin, Amy McKaige
BACKGROUND: Historically IV and enteral fluids given during acute kidney injury (AKI) were restricted before the introduction of continuous renal replacement therapies (CRRT) when more liberal fluids improved nutrition for the critically ill. However fluid accumulation can occur when higher volumes each day are not considered in the fluid balance prescribing and daily review for the NET ultrafiltration (NUF) volume target. KEY MESSAGES: The delivered hours of CRRT each day are vital for achievement of fluid balance and time off therapy makes the task more challenging...
February 20, 2024: Blood Purification
https://read.qxmd.com/read/38377479/effects-of-ingesting-beverages-containing-glycerol-and-sodium-with-isomaltulose-or-sucrose-on-fluid-retention-in-young-adults-a-single-blind-randomized-crossover-trial
#14
JOURNAL ARTICLE
Junto Otsuka, Yumi Okamoto, Yasuaki Enoki, Daisuke Maejima, Naoto Fujii, Glen P Kenny, Toby Mündel, James D Cotter, Tatsuro Amano
We evaluated changes in hyperhydration and beverage hydration index (BHI, a composite measure of fluid balance after consuming a test beverage relative to water) during resting, induced by the consumption of beverages containing glycerol and sodium supplemented with fast-absorbing sucrose or slow-absorbing isomaltulose. In a randomized crossover, single-blinded protocol (clinical trials registry: UMIN000042644), fourteen young physically active adults (3 women) consumed 1 L of beverage containing either 7% glycerol + 0...
February 20, 2024: Applied Physiology Nutrition and Metabolism
https://read.qxmd.com/read/38358490/three-dimensional-simulation-of-the-influence-of-different-flotation-media-in-the-dissolved-air-flotation-tank-through-the-population-balance-model
#15
JOURNAL ARTICLE
Jingming Li, Zhenyu Zhang, Yadi Wang, Zhaodong Huang, Jiahui Xu
Gas-liquid flow in the dissolved air flotation (DAF) tank was studied through computational fluid dynamics through the realizable k-ε model and the population balance model (PBM) to predict the gas content of different flotation mediums (air, carbon dioxide, and chlorine) at different heights of the separation zone in the DAF tank. Simultaneously, a particular focus was placed on studying the effects of bubble aggregation and breakage on gas content. The results indicated that there were virtually no bubbles present in the region below 0...
February 2024: Water Science and Technology: a Journal of the International Association on Water Pollution Research
https://read.qxmd.com/read/38349552/iterative-assessment-of-a-sports-rehydration-beverage-containing-a-novel-amino-acid-formula-on-water-uptake-kinetics
#16
JOURNAL ARTICLE
Mark P Funnell, Loris A Juett, Kirsty M Reynolds, Drusus A Johnson, Ruth M James, Stephen A Mears, Samuel N Cheuvront, Robert W Kenefick, Lewis J James
PURPOSE: Rapid gastric emptying and intestinal absorption of beverages is essential for rapid rehydration, and certain amino acids (AA) may augment fluid delivery. Three sugar-free beverages, containing differing AA concentrations (AA + PZ), were assessed for fluid absorption kinetics against commercial sugar-free (PZ, GZ) and carbohydrate-containing (GTQ) beverages. METHODS: Healthy individuals (n = 15-17 per study) completed three randomised trials...
February 13, 2024: European Journal of Nutrition
https://read.qxmd.com/read/38344178/pharmacokinetics-pharmacodynamics-and-safety-of-15%C3%A2-mg-tolvaptan-administered-orally-for-7-consecutive-days-to-chinese-patients-with-child-pugh-b-cirrhosis
#17
JOURNAL ARTICLE
Hongzhong Liu, Yongfeng Wang, Tao Liu, Yingxuan Chen, Xin Zheng, Ming Liu, Qian Zhao, Minde Zeng, Ji Jiang, Yimin Mao, Pei Hu
Background: Tolvaptan, a selective vasopressin V2 -receptor antagonist, can elicit a diuretic effect without significant electrolyte loss. The aims were to evaluate multiple-dose pharmacokinetics, pharmacodynamics and safety of daily administration of 15 mg tolvaptan in Chinese adult patients with confirmed Child-Pugh Class B cirrhosis accompanied by ascites. Methods: This was an open-label, single-center, single- and multiple-dose study. All patients received a daily 15 mg dose of tolvaptan for 7 consecutive days...
2024: Frontiers in Pharmacology
https://read.qxmd.com/read/38333574/effects-of-the-concentration-and-nature-of-total-dissolved-solids-in-drinking-water-on-feed-intake-nutrient-digestion-energy-balance-methane-emission-ruminal-fermentation-and-blood-constituents-in-different-breeds-of-young-goats-and-hair-sheep
#18
JOURNAL ARTICLE
Amlan Kumar Patra, Luana Paula Dos Santos Ribeiro, Hirut Yirga, Adekayode O Sonibare, Ahmed R Askar, Ali H Hussein, Ryszard Puchala, Arthur Louis Goetsch
Understanding how different livestock species and breeds respond to consumption of brackish water could improve usage of this resource. Therefore, Angora, Boer, and Spanish goat doelings and Dorper, Katahdin, and St. Croix ewe lambs (6 animals per animal type [AT]; initial age = 296 ± 2.1 days) consuming water with varying concentrations of minerals of a natural brackish water source (BR) and sodium chloride (NaCl; SL) were used to determine effects on water and feed intake, nutrient digestion, heat energy, methane emission, ruminal fluid conditions, and blood constituent concentrations...
March 2024: Animal Nutrition
https://read.qxmd.com/read/38320257/nutritional-physiology-and-body-composition-changes-during-a-rapid-ascent-to-high-altitude
#19
JOURNAL ARTICLE
Carmen Santangelo, Vittore Verratti, Simona Mrakic-Sposta, Federica Ciampini, Sofia Bonan, Pamela Pignatelli, Tiziana Pietrangelo, Serena Pilato, Samanta Moffa, Antonella Fontana, Raffaela Piccinelli, Cinzia Le Donne, Lucio Lobefalo, Matteo Beccatelli, Pierluigi Lodi Rizzini, Davide Seletti, Rocco Mecca, Tommaso Beccatelli, Danilo Bondi
Exposure to high altitude might cause the body to adapt with negative energy and fluid balance that compromise body composition and physical performance. In this field study involving 12 healthy adults, sex-balanced, aged 29±4 years with a body mass index 21.6±1.8 kg/m2, we investigated the effects fo a 4-day trekking up to 4556 m a.s.l. on Monte Rosa (Alps, Italy). The food intake was recorded using food diaries and nutrients averages were calculated. The bio-impedance analysis was performed at low and high altitude, and a wearable biosensor (Swemax) was used to track hydro-saline losses in 2 participants...
February 6, 2024: Applied Physiology Nutrition and Metabolism
https://read.qxmd.com/read/38316234/drug-solubility-in-biorelevant-media-in-the-context-of-an-inhalation-based-biopharmaceutics-classification-system-ibcs
#20
JOURNAL ARTICLE
Andreea Floroiu, Brigitta Loretz, Johannes Krämer, Claus-Michael Lehr
An inhalation-based Biopharmaceutical Classification System for pulmonary drugs (iBCS) holds the perspective to allow for scientifically sound prediction of differences in the in vivo performance of orally inhaled drug products (OIDPs). A set of nine drug substances were selected, that are administered via both the oral and pulmonary routes. Their solubility was determined in media representative for the oral (Fasted State Simulated Intestinal Fluid (FaSSIF)) and pulmonary (Alveofact medium and Simulated Lung Fluid (SLF)) routes of administration to confirm the need for a novel approach for inhaled drugs...
February 3, 2024: European Journal of Pharmaceutics and Biopharmaceutics
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