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JOURNAL ARTICLE
Jiafa Chen, Fei Wang, Dawei Zhang, Jinsong Liu, Huaxia Wu, Zhengxian Zhou, Haima Yang, Tingzhen Yan, Tianchen Tang
This paper presents a groundbreaking Ku-band 20W RF front-end power amplifier (PA), designed to address numerous challenges encountered by satellite communication systems, including those pertaining to stability, linearity, cost, and size. The manuscript commences with an exhaustive discussion of system design and operational principles, emphasizing the intricacies of low-noise amplification, and incorporating key considerations such as noise factors, stability analysis, gain, and gain flatness. Subsequently, an in-depth study is conducted on various components of the RF chain, including the pre-amplification module, driver-amplification module, and final-stage amplification module...
2024: PloS One
#22
JOURNAL ARTICLE
Kang Wu, Hao Wang, Meng Yang, Li Liu, Zhenyu Sun, Guojing Hu, Yanpeng Song, Xin Han, Jiangang Guo, Kehui Wu, Baojie Feng, Chengmin Shen, Yuan Huang, Youguo Shi, Zhigang Cheng, Haitao Yang, Lihong Bao, Sokrates T Pantelides, Hong-Jun Gao
Moiré superlattices, consisting of rotationally aligned 2D atomically thin layers, provide a highly novel platform for the study of correlated quantum phenomena. However, reliable and efficient construction of moiré superlattices is challenging because of difficulties to accurately angle-align small exfoliated 2D layers and the need to shun wet-transfer processes. Here, we demonstrate efficient and precise construction of various moiré superlattices by picking up and stacking large-area 2D mono- or few-layer crystals with predetermined crystal axes, made possible by a gold-template-assisted mechanical exfoliation method...
April 10, 2024: Advanced Materials
#23
JOURNAL ARTICLE
Jianhao Chen, Xiongjian Huang, Dandan Yang, Yantong Li, Jiachang Wu, Huakang Yu, Xiaofeng Liu, Jianrong Qiu, Zhongmin Yang, Guoping Dong
The development of novel materials and structures for efficient second-order nonlinear micro/nano devices remains a significant challenge. In this study, we demonstrate the remarkable enhancement of second-harmonic generation (SHG) and even cascaded sum frequency generation (CSFG) in whispering gallery mode microspheres made of surface-crystallized glass with a 6-μm Ba2 TiSi2 O8 crystal layer. Attributed to the core-shell design, the Ba2 TiSi2 O8 located on the surface can be efficiently coupled with whispering gallery modes, resulting in a highly efficient micron-scale cavity-enhanced second-order optical nonlinearity...
April 10, 2024: Advanced Materials
#24
JOURNAL ARTICLE
Munan Hao, Xu Chen, Tianping Ying, Congcong Chai, Jiali Lu, Qi Li, Zhaolong Liu, Mingzhang Yang, Junjie Wang, Ruijin Sun, Donghan Jia, Xinyu Wang, Huiyang Gou, Jian-Gang Guo, Shifeng Jin, Xiaolong Chen
The quest for high-performance piezoelectric materials has been synonymous with the pursuit of the morphotropic phase boundary (MPB), yet the full potential of MPBs remains largely untapped outside of the realm of ferroelectrics. In this study, we reveal a new class of MPB by creating continuous molecular-based solid solutions between centro- and noncentrosymmetric compounds, exemplified by ( tert -butylammonium)1- x ( tert -amylammonium) x FeCl4 (0 ≤ x ≤ 1), where the MPB is formed due to disorder of molecular cations...
April 9, 2024: Journal of the American Chemical Society
#25
JOURNAL ARTICLE
Marella Mahesh, Alka Bali, Tanvi Gupta
RATIONALE: As per International Council for Harmonization (ICH) drug stability test guideline Q1A(R2), inherent stability characteristics of a drug should be studied. This work was designed to investigate inherent degradation characteristics of the drug idelalisib under ICH prescribed stress conditions, identify its degradation products, and postulate their corresponding degradation pathways. METHODS: Idelalisib was subjected to the ICH prescribed conditions of hydrolytic (neutral, acidic, and alkaline), photolytic, oxidative, and thermal stress according to ICH guideline Q1A(R2)...
June 15, 2024: Rapid Communications in Mass Spectrometry: RCM
#26
JOURNAL ARTICLE
Andrea Weber, Vincent T van Hees, Michael J Stein, Sylvia Gastell, Karen Steindorf, Florian Herbolsheimer, Stefan Ostrzinski, Tobias Pischon, Mirko Brandes, Lilian Krist, Michael Marschollek, Karin Halina Greiser, Katharina Nimptsch, Berit Brandes, Carmen Jochem, Anja M Sedlmeier, Klaus Berger, Hermann Brenner, Christoph Buck, Stefanie Castell, Marcus Dörr, Carina Emmel, Beate Fischer, Claudia Flexeder, Volker Harth, Antje Hebestreit, Jana-Kristin Heise, Bernd Holleczek, Thomas Keil, Lena Koch-Gallenkamp, Wolfgang Lieb, Claudia Meinke-Franze, Karin B Michels, Rafael Mikolajczyk, Alexander Kluttig, Nadia Obi, Annette Peters, Börge Schmidt, Sabine Schipf, Matthias B Schulze, Henning Teismann, Sabina Waniek, Stefan N Willich, Michael F Leitzmann, Hansjörg Baurecht
Large population-based cohort studies utilizing device-based measures of physical activity are crucial to close important research gaps regarding the potential protective effects of physical activity on chronic diseases. The present study details the quality control processes and the derivation of physical activity metrics from 100 Hz accelerometer data collected in the German National Cohort (NAKO). During the 2014 to 2019 baseline assessment, a subsample of NAKO participants wore a triaxial ActiGraph accelerometer on their right hip for seven consecutive days...
April 4, 2024: Scientific Reports
#27
JOURNAL ARTICLE
Xin Yu, Qi Yang, Yucheng Tang, Riqiang Gao, Shunxing Bao, Leon Y Cai, Ho Hin Lee, Yuankai Huo, Ann Zenobia Moore, Luigi Ferrucci, Bennett A Landman
PURPOSE: Two-dimensional single-slice abdominal computed tomography (CT) provides a detailed tissue map with high resolution allowing quantitative characterization of relationships between health conditions and aging. However, longitudinal analysis of body composition changes using these scans is difficult due to positional variation between slices acquired in different years, which leads to different organs/tissues being captured. APPROACH: To address this issue, we propose C-SliceGen, which takes an arbitrary axial slice in the abdominal region as a condition and generates a pre-defined vertebral level slice by estimating structural changes in the latent space...
March 2024: Journal of Medical Imaging
#28
JOURNAL ARTICLE
Baoku Wang, Fei Yan, Xingguang Liu, Weimin Sun, Li Li
Metasurfaces hold great promise for terahertz (THz) chiral-optical devices. Here, we proposed a chiral THz metasurface with quasi-bound state in the continuum (BIC) for maximum chirality. By exploiting structural perturbations of the dipole displacement and the diverging angle for the THz metasurface, the symmetry-protected BIC transforms into quasi-BIC. The critical coupling condition is satisfied by the introduction of graphene, enabling the theoretical maximum absorption of the quasi-BIC. Subsequently, the perturbations are balanced to obtain maximum chirality...
March 11, 2024: Optics Express
#29
JOURNAL ARTICLE
Chaojin Zhang, Yu Jiang, Henglei Du, Chengpu Liu
When a two-color Laguerre-Gaussian laser beam propagates through an indium tin oxide (ITO) material, the spatial distributions of odd- and even-order vortex harmonics carrying orbital angular momentum (OAM) are studied. The origin of vortex harmonics can be directly clarified by investigating their dependence on the incident laser field amplitude and frequency. In addition, it is shown that the spectral intensities of vortex harmonics are sensitive to the epsilon-near-zero nonlinear enhancing effects and the thickness of ITO materials...
March 11, 2024: Optics Express
#30
JOURNAL ARTICLE
Jian Cheng, Dingshan Gao, Jianji Dong, Xinliang Zhang
Microresonators facilitate enhanced light-matter interactions within a limited space, showing great promise for nonlinear optics. Here, we demonstrate a high-quality (Q) factor Fabry-Perot microresonator (FPR) for second harmonic generation (SHG) on an x-cut thin film lithium niobate (TFLN) platform. The FPR exhibits Q factors of Qpump = 1.09 × 105 and QSH = 1.15 × 104 at the 1560 nm pump wavelength and 780 nm second harmonic wavelength, respectively...
March 25, 2024: Optics Express
#31
JOURNAL ARTICLE
Sunhao Liu, Xiaoming Wang, Yixuan Dou, Qian Wang, Jiyoon Kim, Carla Slebodnick, Yanfa Yan, Lina Quan
Circularly polarized light emission is a crucial application in imaging, sensing, and photonics. However, utilizing low-energy photons to excite materials, as opposed to high-energy light excitation, can facilitate deep-tissue imaging and sensing applications. The challenge lies in finding materials capable of directly generating circularly polarized nonlinear optical effects. In this study, we introduce a chiral hybrid lead halide (CHLH) material system, R/S-DPEDPb3 Br8 ·H2 O (DPED = 1,2-diphenylethylenediammonium), which can directly produce circularly polarized second harmonic generation (CP-SHG) through linearly polarized infrared light excitation, exhibiting a polarization efficiency as high as 37% at room temperature...
April 3, 2024: Journal of the American Chemical Society
#32
JOURNAL ARTICLE
Arash Aghigh, Gaëtan Jargot, Charlotte Zaouter, Samuel E J Preston, Melika Saadat Mohammadi, Heide Ibrahim, Sonia V Del Rincón, Kessen Patten, François Légaré
This study explored the application of deep learning in second harmonic generation (SHG) microscopy, a rapidly growing area. This study focuses on the impact of glycerol concentration on image noise in SHG microscopy and compares two image restoration techniques: Noise-to-Void 2D (N2V 2D, no reference image restoration) and content-aware image restoration (CARE 2D, full reference image restoration). We demonstrated that N2V 2D effectively restored the images affected by high glycerol concentrations. To reduce sample exposure and damage, this study further addresses low-power SHG imaging by reducing the laser power by 70% using deep learning techniques...
April 2, 2024: Journal of Biophotonics
#33
JOURNAL ARTICLE
Hussein M E Hussein, Seunghwi Kim, Matteo Rinaldi, Andrea Alù, Cristian Cassella
Optical frequency combs, featuring evenly spaced spectral lines, have been extensively studied and applied to metrology, signal processing, and sensing. Recently, frequency comb generation has been also extended to MHz frequencies by harnessing nonlinearities in microelectromechanical membranes. However, the generation of frequency combs at radio frequencies (RF) has been less explored, together with their potential application in wireless technologies. In this work, we demonstrate an RF system able to wirelessly and passively generate frequency combs...
April 2, 2024: Nature Communications
#34
JOURNAL ARTICLE
Chenxinyu Pan, Yuanbiao Tong, Haoliang Qian, Alexey V Krasavin, Jialin Li, Jiajie Zhu, Yiyun Zhang, Bowen Cui, Zhiyong Li, Chenming Wu, Lufang Liu, Linjun Li, Xin Guo, Anatoly V Zayats, Limin Tong, Pan Wang
Two-dimensional single crystal metals, in which the behavior of highly confined optical modes is intertwined with quantum phenomena, are highly sought after for next-generation technologies. Here, we report large area (>104 μm2 ), single crystal two-dimensional gold flakes (2DGFs) with thicknesses down to a single nanometer level, employing an atomic-level precision chemical etching approach. The decrease of the thickness down to such scales leads to the quantization of the electronic states, endowing 2DGFs with quantum-confinement-augmented optical nonlinearity, particularly leading to more than two orders of magnitude enhancement in harmonic generation compared with their thick polycrystalline counterparts...
April 2, 2024: Nature Communications
#35
JOURNAL ARTICLE
Ayako Yamamoto, Kimitoshi Murase, Takeru Sato, Kazumasa Sugiyama, Toru Kawamata, Yoshiyuki Inaguma, Jun-Ichi Yamaura, Kazuki Shitara, Rie Yokoi, Hiroki Moriwake
We synthesized a perovskite-type RbNbO3 at 1173 K and 4 GPa from non-perovskite RbNbO3 and investigated its crystal structure and properties towards ferroelectric material design. Single-crystal X-ray diffraction analysis revealed an orthorhombic cell in the perovskite-type structure (space group Amm 2, no. 38) with a = 3.9937(2) Å, b = 5.8217(3) Å, and c = 5.8647(2) Å. This non-centrosymmetric space group is the same as the ferroelectric BaTiO3 and KNbO3 but with enhanced distortion. Structural transition from orthorhombic to two successive tetragonal phases (Tetra1 at 493 K, Tetra2 at 573 K) was observed, maintaining the perovskite framework before reverting to the triclinic ambient phase at 693 K, with no structural changes between 4 and 300 K...
April 2, 2024: Dalton Transactions: An International Journal of Inorganic Chemistry
#36
Hohyun Cho, Markus Adamek, Jon T Willie, Peter Brunner
Detecting temporal and spectral features of neural oscillations is essential to understanding dynamic brain function. Traditionally, the presence and frequency of neural oscillations are determined by identifying peaks over 1/f noise within the power spectrum. However, this approach solely operates within the frequency domain and thus cannot adequately distinguish between the fundamental frequency of a non-sinusoidal oscillation and its harmonics. Non-sinusoidal signals generate harmonics, significantly increasing the false-positive detection rate - a confounding factor in the analysis of neural oscillations...
March 23, 2024: bioRxiv
#37
JOURNAL ARTICLE
Djebar Hadji, Benamar Baroudi, Toufik Bensafi
CONTEXT: The present work deals with the linear and nonlinear optical properties such as the dipole moment, polarizability, total hyperpolarizability, electric field-induced second harmonic generation, and hyper-Rayleigh scattering first hyperpolarizability of four heterocyclic azo compounds containing the sulfonamide group considered promise in nonlinear optic. The obtained polarizability and hyperpolarizability were supported by the frontier molecular orbital analysis. The properties have been effectively estimated and thoroughly examined to shed light on the nonlinear optical activity based on the density functional theory...
April 2, 2024: Journal of Molecular Modeling
#38
JOURNAL ARTICLE
Atazaz Ahsin, Iqra Ejaz, Sehrish Sarfaraz, Khurshid Ayub, Haitao Ma
Substantial efforts have been made to design and investigate new approaches for high-performance nonlinear optical (NLO) materials. Herein, we report polaron formation in conducting polymers as a new approach to designing materials with a large NLO response. A comparative study of polypyrrole and polypyrrole-based polaron (nPy+ where n = 1, 3, 5, 7, and 9) is carried out for optoelectronic and NLO properties. The studied polarons (PPy+ ) show excellent electronic properties and have reduced ionization potential (IP) as compared to neutral PPy, and a monotonic decrease is observed with increased chain lengths ( 1Py to 9Py )...
March 26, 2024: ACS Omega
#39
JOURNAL ARTICLE
Shun Fujii, Nan Fang, Daiki Yamashita, Daichi Kozawa, Chee Fai Fong, Yuichiro K Kato
Optical nonlinear processes are indispensable in a wide range of applications, including ultrafast lasers, microscopy, and quantum information technologies. Among the diverse nonlinear processes, second-order effects usually overwhelm the higher-order ones, except in centrosymmetric systems, where the second-order susceptibility vanishes to allow the use of the third-order nonlinearity. Here we demonstrate a hybrid photonic platform whereby the balance between second- and third-order susceptibilities can be tuned flexibly...
April 1, 2024: Nano Letters
#40
JOURNAL ARTICLE
Matías J Dahl, Kristopher A Lofgren, Cleo Haugen, Gil E Harmon, Sarah P Hughes, Karen D Cowden Dahl
Uterine carcinosarcoma (UCS) is a rare but aggressive endometrial cancer. Survival outcomes for women diagnosed with UCS remain poor with lower survival than those of endometrioid or high-grade serous uterine cancers. The histopathological hallmark of carcinosarcoma is the presence of both sarcomatous and carcinomatous elements. The survival rates for UCS have not improved for over 40 years; therefore, there is a profound need to identify new treatments. To investigate novel chemotherapy treatment combinations for UCS, we generated a UCS patient-derived organoid (PDO) cell line from a patient that received neoadjuvant treatment with paclitaxel and carboplatin...
2024: Frontiers in Oncology
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