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central auditory processing disorder

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https://www.readbyqxmd.com/read/28286635/maturational-changes-in-ear-advantage-for-monaural-word-recognition-in-noise-among-listeners-with-central-auditory-processing-disorders
#1
Mohsin Ahmed Shaikh, Lisa Fox-Thomas, Denise Tucker
This study aimed to investigate differences between ears in performance on a monaural word recognition in noise test among individuals across a broad range of ages assessed for (C)APD. Word recognition scores in quiet and in speech noise were collected retrospectively from the medical files of 107 individuals between the ages of 7 and 30 years who were diagnosed with (C)APD. No ear advantage was found on the word recognition in noise task in groups less than ten years. Performance in both ears was equally poor...
February 1, 2017: Audiology Research
https://www.readbyqxmd.com/read/28254454/developmental-phonagnosia-linking-neural-mechanisms-with-the-behavioural-phenotype
#2
Claudia Roswandowitz, Stefanie Schelinski, Katharina von Kriegstein
Human voice recognition is critical for many aspects of social communication. Recently, a rare disorder, developmental phonagnosia, which describes the inability to recognise a speaker's voice, has been discovered. The underlying neural mechanisms are unknown. Here, we used two functional magnetic resonance imaging experiments to investigate brain function in two behaviourally well characterised phonagnosia cases, both 32 years old: AS has apperceptive and SP associative phonagnosia. We found distinct malfunctioned brain mechanisms in AS and SP matching their behavioural profiles...
February 22, 2017: NeuroImage
https://www.readbyqxmd.com/read/28188216/amygdalar-gating-of-early-sensory-processing-through-interactions-with-locus-coeruleus
#3
Cynthia D Fast, John P McGann
Fear- and stress-induced activity in the amygdala has been hypothesized to influence sensory brain regions through the influence of the amygdala on neuromodulatory centers. To directly examine this relationship, we used optical imaging to observe odor-evoked activity in populations of olfactory bulb inhibitory interneurons and of synaptic terminals of olfactory sensory neurons (the primary sensory neurons of the olfactory system, which provide the initial olfactory input to the brain) during pharmacological inactivation of amygdala and locus coeruleus (LC) in mice...
March 15, 2017: Journal of Neuroscience: the Official Journal of the Society for Neuroscience
https://www.readbyqxmd.com/read/28181190/distribution-of-alox15-in-the-rat-brain-and-its-role-in-prefrontal-cortical-resolvin-d1-formation-and-spatial-working-memory
#4
Suku-Maran Shalini, Christabel Fung-Yih Ho, Yee-Kong Ng, Jie-Xin Tong, Eng-Shi Ong, Deron R Herr, Gavin S Dawe, Wei-Yi Ong
Docosahexaenoic acid (DHA) is enriched in membrane phospholipids of the central nervous system (CNS) and has a role in aging and neuropsychiatric disorders. DHA is metabolized by the enzyme Alox15 to 17S-hydroxy-DHA, which is then converted to 7S-hydroperoxy,17S-hydroxy-DHA by a 5-lipoxygenase, and thence via epoxy intermediates to the anti-inflammatory molecule, resolvin D1 (RvD1 or 7S,8R,17S-trihydroxy-docosa-Z,9E,11E,13Z,15E,19Z-hexaenoic acid). In this study, we investigated the distribution and function of Alox15 in the CNS...
February 8, 2017: Molecular Neurobiology
https://www.readbyqxmd.com/read/28108252/abnormalities-in-cortical-auditory-responses-in-children-with-central-auditory-processing-disorder
#5
Amineh Koravand, Benoît Jutras, Maryse Lassonde
The main objective of the present study was to identify markers of neural deficits in children with central auditory processing disorder (CAPD) by measuring latency and amplitude of the auditory cortical responses and mismatch negativity (MMN) responses. Passive oddball paradigms were used with nonverbal and verbal stimuli to record cortical auditory-evoked potentials and MMN. Twenty-three children aged 9-12 participated in the study: 10 with normal hearing acuity as well as CAPD and 13 with normal hearing without CAPD...
January 18, 2017: Neuroscience
https://www.readbyqxmd.com/read/28077712/changes-in-properties-of-auditory-nerve-synapses-following-conductive-hearing-loss
#6
Xiaowen Zhuang, Wei Sun, Matthew A Xu-Friedman
Auditory activity plays an important role in the development of the auditory system. Decreased activity can result from conductive hearing loss (CHL) associated with otitis media, which may lead to long-term perceptual deficits. The effects of CHL have been mainly studied at later stages of the auditory pathway, but early stages remain less examined. However, changes in early stages could be important because they would affect how information about sounds is conveyed to higher-order areas for further processing and localization...
January 11, 2017: Journal of Neuroscience: the Official Journal of the Society for Neuroscience
https://www.readbyqxmd.com/read/28054916/a-response-to-dr-jerger-regarding-on-diagnostic-accuracy-in-audiology-central-site-of-lesion-and-central-auditory-processing-disorder-studies
#7
Andrew J Vermiglio
No abstract text is available yet for this article.
January 2017: Journal of the American Academy of Audiology
https://www.readbyqxmd.com/read/28054915/auditory-processing-disorder-as-the-sole-manifestation-of-a-cerebellopontine-and-internal-auditory-canal-lesion
#8
Vasiliki Vivian Iliadou, Nikos Eleftheriadis
BACKGROUND: Clinical importance of auditory processing disorder (APD) testing is often overlooked and regarded with skepticism given the challenging interpretation of results and the current growing debate of its nature and clinical entity. PURPOSE: Presentation of this case is highly educational as APD is the single clinical manifestation of a large cerebellopontine and internal auditory canal lesion. RESEARCH DESIGN: A case report. DATA COLLECTION AND ANALYSIS: The patient underwent a standard audiological evaluation with normal results...
January 2017: Journal of the American Academy of Audiology
https://www.readbyqxmd.com/read/28054914/detailed-audiological-evaluation-of-a-patient-with-xeroderma-pigmentosum-with-neural-degeneration
#9
Danielle Mercer, Annette Hurley, Fern Tsien
BACKGROUND: Xeroderma pigmentosum (XP) is a rare autosomal recessive condition characterized by extreme sensitivity to ultraviolet light. Individuals with XP lack the ability to repair DNA (deoxyribonucleic acid) damage caused by ultraviolet radiation, leading to sunburn and increased susceptibility to skin cancers. Approximately 25% of patients also exhibit neural degeneration, which includes progressive mental deterioration, cortical thinning, and sensorineural hearing loss. PURPOSE: Herein, we describe the audiological and genetic findings in a patient with XP subtype D with neural degeneration and hearing loss...
January 2017: Journal of the American Academy of Audiology
https://www.readbyqxmd.com/read/28040491/temporal-processsing-demands-in-the-hiv-1-transgenic-rat-amodal-gating-and-implications-for-diagnostics
#10
Kristen A McLaurin, Rosemarie M Booze, Charles F Mactutus
Despite the success of combination antiretroviral therapy (cART), approximately 50% of HIV-1 seropositive individuals develop HIV-1 associated neurocognitive disorders (HAND). Unfortunately, point-of-care screening tools for HAND lack sensitivity and specificity, especially in low-resource countries. Temporal processing deficits have emerged as a critical underlying dimension of neurocognitive impairments observed in HIV-1 and may provide a key target for the development of a novel point-of-care screening tool for HAND...
April 2017: International Journal of Developmental Neuroscience
https://www.readbyqxmd.com/read/28018209/speech-comprehension-difficulties-in-chronic-tinnitus-and-its-relation-to-hyperacusis
#11
Veronika Vielsmeier, Peter M Kreuzer, Frank Haubner, Thomas Steffens, Philipp R O Semmler, Tobias Kleinjung, Winfried Schlee, Berthold Langguth, Martin Schecklmann
Objective: Many tinnitus patients complain about difficulties regarding speech comprehension. In spite of the high clinical relevance little is known about underlying mechanisms and predisposing factors. Here, we performed an exploratory investigation in a large sample of tinnitus patients to (1) estimate the prevalence of speech comprehension difficulties among tinnitus patients, to (2) compare subjective reports of speech comprehension difficulties with behavioral measurements in a standardized speech comprehension test and to (3) explore underlying mechanisms by analyzing the relationship between speech comprehension difficulties and peripheral hearing function (pure tone audiogram), as well as with co-morbid hyperacusis as a central auditory processing disorder...
2016: Frontiers in Aging Neuroscience
https://www.readbyqxmd.com/read/28003962/cortical-arousal-in-children-and-adolescents-with-functional-neurological-symptoms-during-the-auditory-oddball-task
#12
Kasia Kozlowska, Dmitriy Melkonian, Chris J Spooner, Stephen Scher, Russell Meares
OBJECTIVE: Stress, pain, injury, and psychological trauma all induce arousal-mediated changes in brain network organization. The associated, high level of arousal may disrupt motor-sensory processing and result in aberrant patterns of motor function, including functional neurological symptoms. We used the auditory oddball paradigm to assess cortical arousal in children and adolescents with functional neurological symptom disorder. METHOD: Electroencephalogram (EEG) data was collected in fifty-seven children and adolescents (41 girls; 16 boys, aged 8...
2017: NeuroImage: Clinical
https://www.readbyqxmd.com/read/28002080/on-the-etiology-of-listening-difficulties-in-noise-despite-clinically-normal-audiograms
#13
Martin Pienkowski
Many people with difficulties following conversations in noisy settings have "clinically normal" audiograms, that is, tone thresholds better than 20 dB HL from 0.1 to 8 kHz. This review summarizes the possible causes of such difficulties, and examines established as well as promising new psychoacoustic and electrophysiologic approaches to differentiate between them. Deficits at the level of the auditory periphery are possible even if thresholds remain around 0 dB HL, and become probable when they reach 10 to 20 dB HL...
March 2017: Ear and Hearing
https://www.readbyqxmd.com/read/27984594/response-to-the-letter-to-the-editor-from-iliadou-sirimanna-and-bamiou-regarding-debonis-2015
#14
David DeBonis
The purpose of this letter is to respond to "Central Auditory Processing Disorder Is Classified in ICD-10 and H93.25 and Hearing Evaluation-Not Screening-Should Be Implemented in Children With Verified Communication and/or Listening Deficits" by Iliadou, Sirimanna, and Bamiou (2016). The methodology used involved a close reading of the concerns expressed by Iliadou et al. in view of the central auditory processing disorder (CAPD) literature and the stated purpose of my original article (DeBonis, 2015). The literature used included clinical practice guidelines, respected journals, and recognized authorities on the topic...
December 1, 2016: American Journal of Audiology
https://www.readbyqxmd.com/read/27984593/capd-is-classified-in-icd-10-as-h93-25-and-hearing-evaluation-not-screening-should-be-implemented-in-children-with-verified-communication-and-or-listening-deficits
#15
Vasiliki Vivian Iliadou, Tony Sirimanna, Doris-Eva Bamiou
The article "It Is Time to Rethink Central Auditory Processing Disorder Protocols for School-Aged Children" (DeBonis, 2015) appeared in the American Journal of Audiology as a tutorial. The author used the argument made by Cowan, Rosen, and Moore (2009), referring to central auditory processing disorder (CAPD), that "such impairments have not been shown to uniquely contribute to a clearly defined condition that would warrant its inclusion in any of the major disease classification systems" (emphasis added; p...
December 1, 2016: American Journal of Audiology
https://www.readbyqxmd.com/read/27942373/impact-of-different-cutoff-criteria-on-rate-of-central-auditory-processing-disorders-diagnosis-using-the-central-test-battery
#16
Mohsin Ahmed Shaikh, Lisa Fox-Thomas, Denise Tucker
The purpose of this study was to quantify how the use of two different cutoff criteria affects the test failure rate and potential diagnosis of central auditory processing disorder ([C]APD) in a sample of children subjected to central auditory processing ([C]AP) assessment. Test failure rates for the central test battery (CTB) using two different cutoff criteria (1 and 2 SDs below the mean) were measured retrospectively for 98 children who completed (C)AP assessment. The rates of potential (C)APD diagnosis ranged from 86...
August 23, 2016: Audiology Research
https://www.readbyqxmd.com/read/27909101/changes-in-properties-of-auditory-nerve-synapses-following-conductive-hearing-loss
#17
Xiaowen Zhuang, Wei Sun, Matthew A Xu-Friedman
Auditory activity plays an important role in the development of the auditory system. Decreased activity can result from conductive hearing loss (CHL) associated with otitis media, which may lead to long-term perceptual deficits. The effects of CHL have been mainly studied at later stages of the auditory pathway, but early stages remain less examined. However, changes in early stages could be important, because they would affect how information about sounds is conveyed to higher order areas for further processing and localization...
December 1, 2016: Journal of Neuroscience: the Official Journal of the Society for Neuroscience
https://www.readbyqxmd.com/read/27888073/early-life-inflammation-with-lps-delays-fear-extinction-in-adult-rodents
#18
V M Doenni, C M Song, M N Hill, Q J Pittman
A large body of evidence has been brought forward connecting developmental immune activation to abnormal fear and anxiety levels. Anxiety disorders have extremely high lifetime prevalence, yet susceptibility factors that contribute to their emergence are poorly understood. In this research we investigated whether an inflammatory insult early in life can alter the response to fear conditioning in adulthood. Fear learning and extinction are important and adaptive behaviors, mediated largely by the amygdala and its interconnectivity with cortico-limbic circuits...
November 22, 2016: Brain, Behavior, and Immunity
https://www.readbyqxmd.com/read/27878599/-acoustic-reflexes-of-children-with-and-without-central-auditory-processing-disorders
#19
S Kunze, A Nickisch, H von Voss, V Mall
BACKGROUND: According to international standards, determination of acoustic reflex thresholds (ART) is one of the established objective measurements in the diagnostic workup of central auditory processing disorders (CAPD). However, there is still no evidence for the significance of ART in CAPD diagnosis. PATIENTS AND METHODS: This study tested 57 children with proven CAPD and 50 healthy children (control group) with regard to group differences in mean ART (sine tones or bandpass-filtered noise)...
November 23, 2016: HNO
https://www.readbyqxmd.com/read/27849243/moyamoya-disease-impact-on-the-performance-of-oral-and-written-language
#20
Dionísia Aparecida Cusin Lamônica, Camila da Costa Ribeiro, Plínio Marcos Duarte Pinto Ferraz, Maria de Lourdes Merighi Tabaquim
Moyamoya disease is an unusual form of occlusive, cerebrovascular disorder that affects the arteries of the central nervous system, causing acquired language alterations and learning difficulties. The study aim was to describe the oral/written language and cognitive skills in a seven-year-and-seven-month-old girl diagnosed with Moyamoya disease. The assessment consisted of interviews with her parents and application of the following instruments: Observation of Communicative Behavior, Peabody Picture Vocabulary Test, Academic Performance Test, Profile of Phonological Awareness, Raven's Progressive Matrices Test, Special Scale, Wechsler Intelligence Scale for Children, Bender Visual Motor Gestalt Test, and Wisconsin Card Sorting Test...
September 2016: CoDAS
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