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iFR pressure wire

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https://www.readbyqxmd.com/read/27101902/continuum-of-vasodilator-stress-from-rest-to-contrast-medium-to-adenosine-hyperemia-for-fractional-flow-reserve-assessment
#1
Nils P Johnson, Allen Jeremias, Frederik M Zimmermann, Julien Adjedj, Nils Witt, Barry Hennigan, Bon-Kwon Koo, Akiko Maehara, Mitsuaki Matsumura, Emanuele Barbato, Giovanni Esposito, Bruno Trimarco, Gilles Rioufol, Seung-Jung Park, Hyoung-Mo Yang, Sérgio B Baptista, George S Chrysant, Antonio M Leone, Colin Berry, Bernard De Bruyne, K Lance Gould, Richard L Kirkeeide, Keith G Oldroyd, Nico H J Pijls, William F Fearon
OBJECTIVES: This study compared the diagnostic performance with adenosine-derived fractional flow reserve (FFR) ≤0.8 of contrast-based FFR (cFFR), resting distal pressure (Pd)/aortic pressure (Pa), and the instantaneous wave-free ratio (iFR). BACKGROUND: FFR objectively identifies lesions that benefit from medical therapy versus revascularization. However, FFR requires maximal vasodilation, usually achieved with adenosine. Radiographic contrast injection causes submaximal coronary hyperemia...
April 25, 2016: JACC. Cardiovascular Interventions
https://www.readbyqxmd.com/read/27076571/quantification-of-the-effect-of-pressure-wire-drift-on-the-diagnostic-performance-of-fractional-flow-reserve-instantaneous-wave-free-ratio-and-whole-cycle-pd-pa
#2
Christopher M Cook, Yousif Ahmad, Matthew J Shun-Shin, Sukhjinder Nijjer, Ricardo Petraco, Rasha Al-Lamee, Jamil Mayet, Darrel P Francis, Sayan Sen, Justin E Davies
BACKGROUND: Small drifts in intracoronary pressure measurements (±2 mm Hg) can affect stenosis categorization using pressure indices. This has not previously been assessed for fractional flow reserve (FFR), instantaneous wave-free ratio (iFR), and whole-cycle distal pressure/proximal pressure (Pd/Pa) indices. METHODS AND RESULTS: Four hundred forty-seven stenoses were assessed with FFR, iFR, and whole-cycle Pd/Pa. Cut point values for significance were predefined as ≤0...
April 2016: Circulation. Cardiovascular Interventions
https://www.readbyqxmd.com/read/25977227/the-instantaneous-wave-free-ratio-ifr-pullback-a-novel-innovation-using-baseline-physiology-to-optimise-coronary-angioplasty-in-tandem-lesions
#3
REVIEW
Sukhjinder S Nijjer, Sayan Sen, Ricardo Petraco, Jamil Mayet, Darrel P Francis, Justin E R Davies
Coronary intervention is increasingly performed in complex disease with tandem and diffuse disease. Pressure wires enable detailed assessment of the physiological significance of a stenosis but in the presence of tandem disease, predicting the impact of a stenting a given stenosis can be difficult and is impeded by flow interaction between stenoses under hyperemia. In this review, we consider the physiological difficulties posed by flow interaction under hyperemia and consider alternative approaches such as assessment under baseline conditions...
April 2015: Cardiovascular Revascularization Medicine: Including Molecular Interventions
https://www.readbyqxmd.com/read/25865272/advances-in-coronary-physiology
#4
REVIEW
Sukhjinder S Nijjer, Sayan Sen, Ricardo Petraco, Justin Er Davies
Pressure-wire technology, most typically fractional flow reserve (FFR), has provided interventional cardiologists with a means of determining the physiological importance of a stenosis during angiography. There has been renewed interest in coronary physiology in the light of guideline recognition, ongoing clinical research and new technologies changing the paradigm of how assessment is performed in the catheter laboratory. We reflect on FFR, with regards the potential effects of changing hemodynamics on FFR and the latest evidence with regards to outcomes...
2015: Circulation Journal: Official Journal of the Japanese Circulation Society
https://www.readbyqxmd.com/read/25459526/pre-angioplasty-instantaneous-wave-free-ratio-pullback-provides-virtual-intervention-and-predicts-hemodynamic-outcome-for-serial-lesions-and-diffuse-coronary-artery-disease
#5
COMPARATIVE STUDY
Sukhjinder S Nijjer, Sayan Sen, Ricardo Petraco, Javier Escaned, Mauro Echavarria-Pinto, Christopher Broyd, Rasha Al-Lamee, Nicolas Foin, Rodney A Foale, Iqbal S Malik, Ghada W Mikhail, Amarjit S Sethi, Mahmud Al-Bustami, Raffi R Kaprielian, Masood A Khan, Christopher S Baker, Michael F Bellamy, Alun D Hughes, Jamil Mayet, Darrel P Francis, Carlo Di Mario, Justin E R Davies
OBJECTIVES: The aim of this study was to perform hemodynamic mapping of the entire vessel using motorized pullback of a pressure guidewire with continuous instantaneous wave-free ratio (iFR) measurement. BACKGROUND: Serial stenoses or diffuse vessel narrowing hamper pressure wire-guided management of coronary stenoses. Characterization of functional relevance of individual stenoses or narrowed segments constitutes an unmet need in ischemia-driven percutaneous revascularization...
December 2014: JACC. Cardiovascular Interventions
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