keyword
MENU ▼
Read by QxMD icon Read
search

Casadevall

keyword
https://www.readbyqxmd.com/read/28483676/selective-testing-for-calreticulin-gene-mutations-in-patients-with-splanchnic-vein-thrombosis-a-prospective-cohort-study
#1
Johanne Poisson, Aurélie Plessier, Jean-Jacques Kiladjian, Fanny Turon, Bruno Cassinat, Annalisa Andreoli, Emmanuelle De Raucourt, Odile Goria, Kamal Zekrini, Christophe Bureau, Florence Lorre, Francisco Cervantes, Dolors Colomer, François Durand, Juan-Carlos Garcia-Pagan, Nicole Casadevall, Dominique-Charles Valla, Pierre-Emmanuel Rautou, Christophe Marzac
BACKGROUND AND AIMS: Myeloproliferative neoplasms (MPN) are the leading cause of splanchnic vein thrombosis (SVT). JAK2(V617F) mutation is found in 80-90% of patients with SVT and MPN. Mutations of the calreticulin (CALR) gene have also been reported. However, as their prevalence ranges from 0 to 2%, the utility of routine testing can be questioned. This study aimed at identifying a group of patients with SVT at high risk of harboring CALR mutations and thus requiring this genetic testing...
May 5, 2017: Journal of Hepatology
https://www.readbyqxmd.com/read/28450275/evolution-of-biological-agents-how-established-drugs-can-become-less-safe
#2
Nicole Casadevall, Oliver Flossmann, David Hunt
No abstract text is available yet for this article.
April 27, 2017: BMJ: British Medical Journal
https://www.readbyqxmd.com/read/28435888/continental-drift-and-speciation-of-the-cryptococcus-neoformans-and-cryptococcus-gattii-species-complexes
#3
Arturo Casadevall, Joudeh B Freij, Christopher Hann-Soden, John Taylor
Genomic analysis has placed the origins of two human-pathogenic fungi, the Cryptococcus gattii species complex and the Cryptococcus neoformans species complex, in South America and Africa, respectively. Molecular clock calculations suggest that the two species separated ~80 to 100 million years ago. This time closely approximates the breakup of the supercontinent Pangea, which gave rise to South America and Africa. On the basis of the geographic distribution of these two species complexes and the coincidence of the evolutionary divergence and Pangea breakup times, we propose that a spatial separation caused by continental drift resulted in the emergence of the C...
March 2017: MSphere
https://www.readbyqxmd.com/read/28410490/survival-of-86-690-patients-with-thyroid-cancer-a-population-based-study-in-29-european-countries-from-eurocare-5
#4
L Dal Maso, A Tavilla, F Pacini, D Serraino, B A C van Dijk, M D Chirlaque, R Capocaccia, N Larrañaga, M Colonna, D Agius, E Ardanaz, J Rubió-Casadevall, A Kowalska, S Virdone, S Mallone, H Amash, R De Angelis
BACKGROUND: Incidence rates of thyroid cancer (TC) increased in several countries during the last 30 years, while mortality rates remained unchanged, raising important questions for treatment and follow-up of TC patients. This study updates population-based estimates of relative survival (RS) after TC diagnosis in Europe by sex, country, age, period and histology. METHODS: Data from 87 cancer registries in 29 countries were extracted from the EUROCARE-5 dataset...
April 11, 2017: European Journal of Cancer
https://www.readbyqxmd.com/read/28400494/uv-b-inhibits-leaf-growth-through-changes-in-growth-regulating-factors-and-gibberellin-levels
#5
Julieta Fina, Romina Casadevall, Hamada AbdElgawad, Els Prinsen, Marios Nektarios Markakis, Gerrit T S Beemster, Paula Casati
UV-B radiation affects leaf growth in a wide range of species. In this work, we demonstrate that UV-B levels present in solar radiation inhibits maize leaf growth without causing any other visible stress symptoms, including accumulation of DNA damage. We conducted kinematic analyses of cell division and expansion to understand the impact of UV-B radiation on these cellular processes. Our results demonstrate that the decrease in leaf growth in UV-B irradiated leaves is a consequence of a reduction in cell production, and a shortened growth zone (GZ)...
April 11, 2017: Plant Physiology
https://www.readbyqxmd.com/read/28377532/acknowledgment-of-invited-editors
#6
Arturo Casadevall
No abstract text is available yet for this article.
April 4, 2017: MBio
https://www.readbyqxmd.com/read/28375703/chemical-and-biological-dynamics-using-droplet-based-microfluidics
#7
Oliver Dressler, Xavier Casadevall I Solvas, Andrew J deMello
Recent years have witnessed an increased use of droplet-based microfluidic techniques in a wide variety of chemical and biological assays. Nevertheless, obtaining dynamic data from these platforms has remained challenging, as this often requires reading the same droplets (possibly thousands of them) multiple times over a wide range of intervals (from milliseconds to hours). In this review, we introduce the elemental techniques for the formation and manipulation of microfluidic droplets, together with the most recent developments in these areas...
March 24, 2017: Annual Review of Analytical Chemistry
https://www.readbyqxmd.com/read/28362950/crisis-in-infectious-diseases-2-decades-later
#8
Arturo Casadevall
No abstract text is available yet for this article.
April 1, 2017: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
https://www.readbyqxmd.com/read/28278283/enhanced-control-of-mycobacterium-tuberculosis-extrapulmonary-dissemination-in-mice-by-an-arabinomannan-protein-conjugate-vaccine
#9
Rafael Prados-Rosales, Leandro Carreño, Tingting Cheng, Caroline Blanc, Brian Weinrick, Adel Malek, Todd L Lowary, Andres Baena, Maju Joe, Yu Bai, Rainer Kalscheuer, Ana Batista-Gonzalez, Noemi A Saavedra, Leticia Sampedro, Julen Tomás, Juan Anguita, Shang-Cheng Hung, Ashish Tripathi, Jiayong Xu, Aharona Glatman-Freedman, Williams R Jacobs, John Chan, Steven A Porcelli, Jacqueline M Achkar, Arturo Casadevall
Currently there are a dozen or so of new vaccine candidates in clinical trials for prevention of tuberculosis (TB) and each formulation attempts to elicit protection by enhancement of cell-mediated immunity (CMI). In contrast, most approved vaccines against other bacterial pathogens are believed to mediate protection by eliciting antibody responses. However, it has been difficult to apply this formula to TB because of the difficulty in reliably eliciting protective antibodies. Here, we developed capsular polysaccharide conjugates by linking mycobacterial capsular arabinomannan (AM) to either Mtb Ag85b or B...
March 2017: PLoS Pathogens
https://www.readbyqxmd.com/read/28256187/melanin-radiation-and-energy-transduction-in-fungi
#10
Arturo Casadevall, Radames J B Cordero, Ruth Bryan, Joshua Nosanchuk, Ekaterina Dadachova
Melanin pigments are found in many diverse fungal species, where they serve a variety of functions that promote fitness and cell survival. Melanotic fungi inhabit some of the most extreme habitats on earth such as the damaged nuclear reactor at Chernobyl and the highlands of Antarctica, both of which are high-radiation environments. Melanotic fungi migrate toward radioactive sources, which appear to enhance their growth. This phenomenon, combined with the known capacities of melanin to absorb a broad spectrum of electromagnetic radiation and transduce this radiation into other forms of energy, raises the possibility that melanin also functions in harvesting such energy for biological usage...
March 2017: Microbiology Spectrum
https://www.readbyqxmd.com/read/28251180/the-pathogenic-potential-of-a-microbe
#11
Arturo Casadevall
Virulence is a microbial property that is realized only in susceptible hosts. There is no absolute measurement for virulence, and consequently it is always measured relative to a standard, usually another microbe or host. This article introduces the concept of pathogenic potential, which provides a new approach to measuring the capacity of microbes for virulence. The pathogenic potential is proportional to the fraction of individuals who become symptomatic after infection with a defined inoculum and can include such attributes as mortality, communicability, and the time from infection to disease...
January 2017: MSphere
https://www.readbyqxmd.com/read/28186976/32-phosphorus-selectively-delivered-by-listeria-to-pancreatic-cancer-demonstrates-a-strong-therapeutic-effect
#12
Dinesh Chandra, Benson Chellakkan Selvanesan, Ziqiang Yuan, Steven K Libutti, Wade Koba, Amanda Beck, Kun Zhu, Arturo Casadevall, Ekaterina Dadachova, Claudia Gravekamp
Our laboratory has developed a novel delivery platform using an attenuated non-toxic and non-pathogenic bacterium Listeria monocytogenes that infects tumor cells and selectively survives and multiplies in metastases and primary tumors with help of myeloid-derived suppressor cells (MDSC) and immune suppression in the tumor microenvironment (TME). 32P was efficiently incorporated into the Listeria bacteria by starvation of the bacteria in saline, and then cultured in phosphorus-free medium complemented with 32P as a nutrient...
March 28, 2017: Oncotarget
https://www.readbyqxmd.com/read/28174305/the-mbio-american-academy-of-microbiology-submission-track-in-2017
#13
EDITORIAL
Arturo Casadevall, Thomas Shenk
No abstract text is available yet for this article.
February 7, 2017: MBio
https://www.readbyqxmd.com/read/28126951/reply-to-on-the-impact-factor-and-the-asm-editorial-policy
#14
Ferric C Fang, Arturo Casadevall
No abstract text is available yet for this article.
February 2017: Infection and Immunity
https://www.readbyqxmd.com/read/28101535/the-case-for-adopting-the-species-complex-nomenclature-for-the-etiologic-agents-of-cryptococcosis
#15
Kyung J Kwon-Chung, John E Bennett, Brian L Wickes, Wieland Meyer, Christina A Cuomo, Kurt R Wollenburg, Tihana A Bicanic, Elizabeth Castañeda, Yun C Chang, Jianghan Chen, Massimo Cogliati, Françoise Dromer, David Ellis, Scott G Filler, Matthew C Fisher, Thomas S Harrison, Steven M Holland, Shigeru Kohno, James W Kronstad, Marcia Lazera, Stuart M Levitz, Michail S Lionakis, Robin C May, Popchai Ngamskulrongroj, Peter G Pappas, John R Perfect, Volker Rickerts, Tania C Sorrell, Thomas J Walsh, Peter R Williamson, Jianping Xu, Adrian M Zelazny, Arturo Casadevall
Cryptococcosis is a potentially lethal disease of humans/animals caused by Cryptococcus neoformans and Cryptococcus gattii. Distinction between the two species is based on phenotypic and genotypic characteristics. Recently, it was proposed that C. neoformans be divided into two species and C. gattii into five species based on a phylogenetic analysis of 115 isolates. While this proposal adds to the knowledge about the genetic diversity and population structure of cryptococcosis agents, the published genotypes of 2,606 strains have already revealed more genetic diversity than is encompassed by seven species...
January 2017: MSphere
https://www.readbyqxmd.com/read/28099836/antibodies-to-mycobacterium-tuberculosis
#16
Arturo Casadevall
No abstract text is available yet for this article.
January 19, 2017: New England Journal of Medicine
https://www.readbyqxmd.com/read/28066619/clinical-management-of-chronic-obstructive-pulmonary-disease-patients-with-muscle-dysfunction
#17
REVIEW
Joaquim Gea, Carme Casadevall, Sergi Pascual, Mauricio Orozco-Levi, Esther Barreiro
Muscle dysfunction is frequently observed in chronic obstructive pulmonary disease (COPD) patients, contributing to their exercise limitation and a worsening prognosis. The main factor leading to limb muscle dysfunction is deconditioning, whereas respiratory muscle dysfunction is mostly the result of pulmonary hyperinflation. However, both limb and respiratory muscles are also influenced by other negative factors, including smoking, systemic inflammation, nutritional abnormalities, exacerbations and some drugs...
November 2016: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/28039306/acknowledgment-of-reviewers
#18
EDITORIAL
Arturo Casadevall
No abstract text is available yet for this article.
December 30, 2016: MBio
https://www.readbyqxmd.com/read/28031206/physiological-differences-in-cryptococcus-neoformans-strains-in-vitro-versus-in-vivo-and-their-effects-on-antifungal-susceptibility
#19
REVIEW
Nina T Grossman, Arturo Casadevall
Cryptococcus neoformans is an environmentally ubiquitous fungal pathogen that primarily causes disease in people with compromised immune systems, particularly those with advanced AIDS. There are estimated to be almost 1 million cases per year of cryptococcal meningitis in patients infected with human immunodeficiency virus, leading to over 600,000 annual deaths, with a particular burden in sub-Saharan Africa. Amphotericin B (AMB) and fluconazole (FLC) are key components of cryptococcal meningitis treatment: AMB is used for induction, and FLC is for consolidation, maintenance and, for occasional individuals, prophylaxis...
March 2017: Antimicrobial Agents and Chemotherapy
https://www.readbyqxmd.com/read/28011050/could-the-addition-of-cetuximab-to-conventional-radiation-therapy-improve-organ-preservation-in-those-patients-with-locally-advanced-larynx-cancer-who-respond-to-induction-chemotherapy-an-organ-preservation-spanish-head-and-neck-cancer-cooperative-group-phase
#20
Ricard Mesía, Jose A Garcia-Saenz, Alicia Lozano, Miguel Pastor, Juan J Grau, Javier Martínez-Trufero, Julio Lambeaz, Joaquina Martínez-Galán, Jose R Mel, Belen González, Silvia Vázquez, Manel Mañós, Miren Taberna, Beatriz Cirauqui, Elvira Del Barco, Esther Casado, Jordi Rubió-Casadevall, Angles Rodríguez-Jaráiz, Juan J Cruz
PURPOSE: To evaluate the efficacy and safety of induction chemotherapy (IC) followed by bioradiotherapy (BRT) to achieve functional larynx preservation in the setting of locally advanced head and neck tumors. METHODS AND MATERIALS: This was a phase 2, open-label, multicenter study of patients with stage III and IVA laryngeal carcinoma who were candidates for total laryngectomy. The primary endpoint was the rate of survival with functional larynx (SFL) at 3 years, with a critical value to consider the study positive of SFL >59%...
March 1, 2017: International Journal of Radiation Oncology, Biology, Physics
keyword
keyword
83091
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"