Ming Liu, Bingtai Lu, Yue Li, Shuofeng Yuan, Zhen Zhuang, Guangyu Li, Dong Wang, Liuheyi Ma, Jianheng Zhu, Jinglu Zhao, Chris Chung-Sing Chan, Vincent Kwok-Man Poon, Kenn Ka-Heng Chik, Zhiyao Zhao, Huifang Xian, Jingxian Zhao, Jincun Zhao, Jasper Fuk-Woo Chan, Yuxia Zhang
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causative agent of coronavirus disease 2019 (COVID-19), has had a significant impact on healthcare systems and economies worldwide. The continuous emergence of new viral strains presents a major challenge in the development of effective antiviral agents. Strategies that possess broad-spectrum antiviral activities are desirable to control SARS-CoV-2 infection. ACE2, an angiotensin-containing enzyme that prevents the overactivation of the renin angiotensin system, is the receptor for SARS-CoV-2...
October 9, 2023: Signal Transduction and Targeted Therapy