Sien De Koster, Basil Britto Xavier, Christine Lammens, Natascha Perales Selva, Stefanie van Kleef-van Koeveringe, Samuel Coenen, Youri Glupczynski, Isabel Leroux-Roels, Wouter Dhaeze, Christian J P A Hoebe, Jeroen Dewulf, Arjan Stegeman, Marjolein Kluytmans-Van den Bergh, Jan Kluytmans, Herman Goossens
BACKGROUND: Colistin serves as the last line of defense against multidrug resistant Gram-negative bacterial infections in both human and veterinary medicine. This study aimed to investigate the occurrence and spread of colistin-resistant Enterobacterales (ColR-E) using a One Health approach in Belgium and in the Netherlands. METHODS: In a transnational research project, a total of 998 hospitalized patients, 1430 long-term care facility (LTCF) residents, 947 children attending day care centres, 1597 pigs and 1691 broilers were sampled for the presence of ColR-E in 2017 and 2018, followed by a second round twelve months later for hospitalized patients and animals...
2024: PloS One