Amanda J Driscoll, Fadima Cheick Haidara, Milagritos D Tapia, Emily L Deichsel, Ousmane S Samake, Tiecoura Bocoum, Jason A Bailey, Meagan C Fitzpatrick, Robert L Goldenberg, Mamoudou Kodio, Lawrence H Moulton, Dilruba Nasrin, Uma Onwuchekwa, Allison M Shaffer, Samba O Sow, Karen L Kotloff
INTRODUCTION: In high mortality settings, prophylactic azithromycin has been shown to improve birth weight and gestational age at birth when administered antenatally, to reduce the incidence of neonatal infections when administered intrapartum, and to improve survival when administered in infancy. Questions remain regarding whether azithromycin can prevent stillbirths, and regarding the optimal strategy for the delivery of azithromycin to pregnant women and their infants. METHODS AND ANALYSIS: Sauver avec l'Azithromycine en Traitant les Femmes Enceintes et les Enfants (SANTE) is a 2×2 factorial, individually randomised, placebo-controlled, double-masked trial in rural Mali...
August 30, 2023: BMJ Open