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Tetsuya Iidaka
Humor perception is a ubiquitous phenomenon in human societies. In theories of humor perception, three factors, non-seriousness, social context, and incongruity, have been implicated in humor. In another theory, however, elaboration and reinterpretation of contexts are considered to play a role in eliciting humor. Although the neural correlates of humor appreciation have been investigated using neuroimaging methods, only a few studies have conducted such experiments under natural conditions. In the present study, two functional magnetic resonance imaging experiments, using a comedy movie as a stimulus, were conducted to investigate the neural correlates of humor under natural conditions...
October 18, 2016: Cerebral Cortex
Michel Komajda
Ivabradine is a blocker of the funny current channels in the sinoatrial node cells. This results in pure heart rate reduction when elevated without direct effect on contractility or on the vessels. It was tested in a large outcome clinical trial in stable chronic heart failure (CHF) with low ejection fraction, in sinus rhythm, on a contemporary background therapy including betablockers (SHIFT: Systolic Heart Failure Treatment with the If inhibitor Trial).The primary composite endpoint (cardiovascular mortality or heart failure hospitalization) was reduced by 18% whereas the first occurrence of heart failure hospitalizations was reduced by 26%...
October 18, 2016: Handbook of Experimental Pharmacology
Sarah L Turley, Kerry E Francis, Denise K Lowe, William D Cahoon
Control of ventricular rate is recommended for patients with paroxysmal, persistent, or permanent atrial fibrillation (AF). Existing rate-control options, including beta-blockers, nondihydropyridine calcium channel blockers, and digoxin, are limited by adverse hemodynamic effects and their ability to attain target heart rate (HR). Ivabradine, a novel HR-controlling agent, decreases HR through deceleration of conduction through If ('funny') channels, and is approved for HR reduction in heart failure patients with ejection fraction less than 35% and elevated HR, despite optimal pharmacological treatment...
September 22, 2016: Therapeutic Advances in Cardiovascular Disease
Lisa H Amir, Anita Bearzatto
BACKGROUND: Women who are breastfeeding often consult their general practitioner (GP) with concerns about nipple and breast pain, or the adequacy of their milk supply. Common concerns for their breastfed infant include slow weight gain, 'fussiness' with breastfeeding and 'funny stools'. OBJECTIVE: This article offers suggestions for clinicians to support breastfeeding women and their infants. DISCUSSION: Good attachment to the breast is important to reduce nipple pain and trauma, and to ensure adequate breast drainage and ongoing milk supply...
August 2016: Australian Family Physician
Charlotte Hilton
AIMS AND OBJECTIVES: To report the findings from a unique analysis of naturally occurring data regarding self-harm behaviour generated through the global social media site, Twitter. BACKGROUND: Self-harm behaviours are of global concern for health and social care practice. However, little is known about the experiences of those who harm and the attitudes of the general public towards such behaviours. A deeper, richer and more organic understanding of this is vital to informing global approaches to supporting individuals through treatment and recovery...
September 7, 2016: Journal of Clinical Nursing
Ajay Gupta
No abstract text is available yet for this article.
July 2016: Epilepsy Currents
Francesca D'Errico, Isabella Poggi
Research on socially aware systems requires fine-grained knowledge of the mechanisms of persuasion in order to promote civic knowledge and aware political participation. Within humor studies, political parody is generally considered a simple pleasant weapon for political evaluation, currently explained by referring to the so called "just a joke effect" (Nabi et al., 2007). Indeed the funny side of parody can induce positive emotions, but it also includes a discrediting act that sometimes produces a "bitter laughter...
2016: Frontiers in Psychology
Theresa E DiDonato, Brittany K Jakubiak
Not all humor is the same, yet little is known about the appeal of specific humor styles in romantic initiation. The current experimental study addresses this gap by investigating how romantic motives (short-term or long-term) affect individuals' anticipated use of, and response to, positive humor and negative humor. Heterosexual participants (n = 224) imagined the pursuit of either a desired short-term or long-term relationship, indicated the extent to which they would produce positive and negative humor, and reported how their own interest would change in response to the imaginary target's use of positive or negative humor...
August 2016: Europe's journal of psychology
Brooke Swash, Nick Hulbert-Williams, Ros Bramwell
Despite high levels of psychological distress, there is a scarcity of research on unmet supportive care needs in haematological cancer patients. This qualitative study used an in-depth interpretative phenomenological approach to investigate the needs reported by six non-Hodgkin's lymphoma patients and explored how these needs consequently shaped the patient experience. Emergent themes included the following: concerns for family, information needs and the need for psychological support. Participants reported feeling different to other cancer patients...
July 28, 2016: Journal of Health Psychology
Thomas F Hansen
Bias is a funny term. Its vernacular meaning is a lack of objectivity resulting in partial or prejudiced view or reporting on a subject. To anyone but a statistician a characterization of a method as biased sounds like a devastating criticism. In statistics, however, bias has a precise meaning as the difference between the expected value of an estimator and the true value of the parameter it seeks to estimate. Some good estimators are biased, and some unbiased estimators are not good. A better criterion for a good estimator is accuracy, the expected distance from the true value...
July 10, 2016: Journal of Evolutionary Biology
Simon Stewart, Joshua F Wiley, Cressida J McDermott, David R Thompson
BACKGROUND: This study aimed to confirm, in a large, diverse cohort of elite Stand-up Comedians and other entertainers, that there is an inverse association between comedic ability and longevity. METHODS: This retrospective cohort study included 200 Stand-up Comedians (13% women), 113 Comedy Actors (17.5% women), and 184 Dramatic Actors (29.3% women) listed in the top 200 in each category in a popular online ranking website. Longevity within each group was examined adjusting for life expectancy by year of birth and within-group ranking score...
October 1, 2016: International Journal of Cardiology
Aimee K Gardner, Jesse Clanton, Ibrahim I Jabbour, Lauren Scott, Daniel J Scott, Michael A Russo
BACKGROUND: A common strategy to increase learner engagement is to interweave educational material with interesting but slightly tangential tidbits of information (eg, "war stories" and funny anecdotes), known as seductive details. Our objective was to examine the impact of seductive details on initial acquisition and transfer of basic laparoscopic surgical skills. METHODS: Novices (first- to fourth-year medical students) were randomized into control (N = 47) or seductive details (N = 42) groups...
September 2016: Surgery
Matthew F Nolan
No abstract text is available yet for this article.
July 1, 2016: Journal of Physiology
Feng Yu, Yuexia Li, Jian Yang, Jin Qian, Xining Li, Chongbin Liu
Epidemiological studies show that maternal cigarette smoking is associated with an increased risk of cardiovascular diseases in postnatal life. Baroreflex sensitivity (BRS) is an important index for evaluating the homeostasis of the cardiovascular system. This experiment was designed to investigate the possible mechanism of prenatal nicotine on the adult male offspring's heart rate (HR) increase due to BRS. Pregnant rats received the 0.3 ml of saline or nicotine (1.5 mg kg(-1)) by subcutaneous injection from gestational days 3 to 21...
June 13, 2016: Cardiovascular Toxicology
Laura Thomas
No abstract text is available yet for this article.
February 2016: Lancet Psychiatry
Dan Ariely, Beatrice Popescu
The idea of interviewing Dan Ariely was somehow latent on my mind since I started being interested in cognitive psychology and cognitive behavior psychotherapy, but actually got more ardent ever since irrationality became a research topic for his team at Duke University. I picked him as an interviewee thinking not only at his exceptional skills as a researcher and as Kahnemann 'disciple', but mainly for his fantastic wit, true modesty and utmost interest in making people's lives easier and more comfortable, by creating awareness on a lot of topics otherwise neglected...
November 2015: Europe's journal of psychology
Zachary J J Roper, Shaun P Vecera
Stimuli associated with monetary reward can become powerful cues that effectively capture visual attention. We examined whether such value-driven attentional capture can be induced with monetary feedback in the absence of an expected cash payout. To this end, we implemented images of U.S. dollar bills as reward feedback. Participants knew in advance that they would not receive any money based on their performance. Our reward stimuli-$5 and $20 bill images-were thus dissociated from any practical utility. Strikingly, we observed a reliable attentional capture effect for the mere images of bills...
October 2016: Attention, Perception & Psychophysics
Marie-Louise Mares, Anne Bartsch, James Alex Bonus
Two studies considered age differences in the roles of emotion and meaningfulness in adults' media preferences. Socioemotional Selectivity Theory (SST) suggests that with increasing age, positive emotions become more meaningful, and emotional meaningfulness matters more for situation selection. Other developmental descriptions suggest that negative affect may be meaningful and interesting in youth. In Study 1, United States 18-86 year olds read descriptions of TV programs that varied in levels of warmth, funniness, sadness, and fright; in Study 2, United States and German 18-82 year olds watched film trailers that varied in levels of gore and meaningfulness...
August 2016: Psychology and Aging
Kristina B Hood, Natalie J Shook, Faye Z Belgrave
This study examined which characteristics of persuasive communications are most effective in changing African American women's condom use attitudes. Focus groups were convened with 40 African American women (Mage = 25.54, SD = 4.67) to assess their opinions on current effective strategies used to promote condom use among their peers. Participants discussed effective characteristics of messaging campaigns (i.e., source, message type, channel) and how these could be used in future prevention messages. Findings revealed that making messages that are fun, catchy, and informative, delivered frequently through social media, TV, or radio by a peer or celebrity would be perceived as most effective in changing young African American women's attitudes...
May 2, 2016: Journal of Sex Research
Yuanyuan Feng, Shouming Luo, Pan Yang, Zhiyuan Song
The 'funny' current, also known as the If current, play a crucial role in the spontaneous diastolic depolarization of sinoatrial node cells. The If current is primarily induced by the protein encoded by the hyperpolarization-activated cyclic nucleotide-gated channel 4 (HCN4) gene. The functional If channel can be reconstructed in canine mesenchymal stem cells (cMSCs) transfected with mouse HCN4 (mHCN4). Biomimetic studies have shown that electric pulse current stimulation (EPCS) can promote cardiogenesis in cMSCs...
April 2016: Experimental and Therapeutic Medicine
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