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Computed coronary angiography

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https://www.readbyqxmd.com/read/28550587/epicardial-adipose-tissue-is-associated-with-high-risk-plaque-feature-progression-in-non-culprit-lesions
#1
Yahang Tan, Jia Zhou, Ying Zhou, Xiaobo Yang, Jing Wang, Yundai Chen
Several studies have suggested a link between epicardial adipose tissue (EAT) volume and high-risk plaques (HRPs); however, little is known about the association between EAT volume and HRP progression in non-culprit lesions (NCLs). Therefore, we evaluated whether EAT can independently predict HRP characteristic progression in NCLs by coronary computed tomography angiography (CCTA). In this single-centre trial, we analysed 131 consecutive patients (median age 61 years, male 72.52%) undergoing CCTA with percutaneous coronary intervention (PCI) for culprit lesions...
May 26, 2017: International Journal of Cardiovascular Imaging
https://www.readbyqxmd.com/read/28550355/coronary-computed-tomography-angiography-using-128-slice-dual-source-computed-tomography-in-patients-with-severe-calcification
#2
Suguru Sato, Yosuke Horii, Norihiko Yoshimura, Takuya Yagi, Hidefumi Aoyama
PURPOSE: To compare coronary computed tomography angiography (CTA) and coronary angiography (CAG) with regard to luminal graphic definition of calcified segments using 128-slice dual-source computed tomography (DSCT), specifically for patients with an Agatston score >400. MATERIALS AND METHODS: Of 1148 consecutive patients who underwent coronary CTA using a 128-slice DSCT, 132 subjects had severe calcification with an Agatston score >400. Thirty-nine of the 132 patients who had undergone CAG within 3 months before or after coronary CTA were included...
May 26, 2017: Japanese Journal of Radiology
https://www.readbyqxmd.com/read/28549694/d-dimer-is-associated-with-arterial-and-venous-coronary-artery-bypass-graft-occlusion
#3
Alessandro Parolari, Laura Cavallotti, Daniele Andreini, Veronika Myasoedova, Cristina Banfi, Marina Camera, Paolo Poggio, Fabio Barili, GianLuca Pontone, Luciana Mussoni, Chiara Centenaro, Francesco Alamanni, Elena Tremoli
OBJECTIVE: In this observational prospective study, we assessed the role of clinical variables and circulating biomarkers in graft occlusion at 18 months to identify a signature for graft occlusion. METHODS: A total of 330 patients undergoing primary elective coronary artery bypass grafting were enrolled. Blood collection for biomarker assessment was performed before surgery and discharge. Patients were then scheduled to undergo coronary computed tomography angiography at 18 months follow-up, and 179 patients underwent coronary computed tomography angiography 18 ± 2 months postoperatively...
April 27, 2017: Journal of Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/28549614/validation-and-comparison-of-four-models-to-calculate-pretest-probability-of-obstructive-coronary-artery-disease-in-a-chinese-population-a-coronary-computed-tomographic-angiography-study
#4
Jia Zhou, Yujie Liu, Lingyu Huang, Yahang Tan, Xingchen Li, Hong Zhang, Yanhe Ma, Ying Zhang
OBJECTIVE: We sought to compare the performance of the updated Diamond-Forrester method (UDFM), Duke clinical score (DCS), Genders clinical model (GCM) and Genders extended model (GEM) in a Chinese population referred to coronary computed tomography angiography (coronary CTA). BACKGROUND: The reliability of existing models to calculate the pretest proability (PTP) of obstructive coronary artery disease (CAD) have not been fully investigated, especially in a Chinese population...
May 11, 2017: Journal of Cardiovascular Computed Tomography
https://www.readbyqxmd.com/read/28549119/systematic-review-of-cost-effectiveness-of-myocardial-perfusion-scintigraphy-in-patients-with-ischaemic-heart-disease-a-report-from-the-cardiovascular-committee-of-the-european-association-of-nuclear-medicine-endorsed-by-the-european-association-of-cardiovascular
#5
Elin Trägårdh, Siok Swan Tan, Jan Bucerius, Alessia Gimelli, Oliver Gaemperli, Oliver Lindner, Denis Agostini, Christopher Übleis, Roberto Sciagrà, Riemer H Slart, S Richard Underwood, Fabien Hyafil, Marcus Hacker, Hein J Verberne
Coronary artery disease (CAD) is a major cause of death and disability. Several diagnostic tests, such as myocardial perfusion scintigraphy (MPS), are accurate for the detection of CAD, as well as having prognostic value for the prediction of cardiovascular events. Nevertheless, the diagnostic and prognostic value of these tests should be cost-effective and should lead to improved clinical outcome. We have reviewed the literature on the cost-effectiveness of MPS in different circumstances: (i) the diagnosis and management of CAD; (ii) comparison with exercise electrocardiography (ECG) and other imaging tests; (iii) as gatekeeper to invasive coronary angiography (ICA), (iv) the impact of appropriate use criteria; (v) acute chest pain, and (vi) screening of asymptomatic patients with type-2 diabetes...
May 26, 2017: European Heart Journal Cardiovascular Imaging
https://www.readbyqxmd.com/read/28549022/pictorial-review-of-surgical-anatomy-in-adult-congenital-heart-disease
#6
Carlo N De Cecco, Giuseppe Muscogiuri, José M Madrid Pérez, Marwen Eid, Pal Suranyi, Virginia W Lesslie, Gorka Bastarrika
The survival rate of patients with congenital heart disease (CHD) has dramatically improved over the last 2 decades because of technological and surgical advances in diagnosis and treatment, respectively. The vast majority of CHD patients are, in fact, amenable to treatment by either device closure or surgery. Considering the wide spectrum of surgical procedures and complex native and derived anatomy, continuous and detailed follow-up is of paramount importance. Cardiac magnetic resonance and cardiac computed tomography angiography are the cornerstones of diagnosis and follow-up of CHD, allowing for comprehensive noninvasive assessment of the heart, coronary tree, and intrathoracic great vessels, along with both morphological and functional evaluation...
May 25, 2017: Journal of Thoracic Imaging
https://www.readbyqxmd.com/read/28540210/integration-of-non-invasive-functional-assessments-with-anatomical-risk-stratification-in-complex-coronary-artery-disease-the-non-invasive-functional-syntax-score
#7
REVIEW
Carlos Collet, Yoshinobu Onuma, Yosuke Miyazaki, Marie-Angèle Morel, Patrick W Serruys
Since the early days of coronary angiography, the extension and severity of coronary artery disease (CAD) have been used for risk stratification. The SYNTAX score objectively characterizes CAD in patients with multivessel disease. Furthermore, recalculating the SYNTAX score by the incorporation of the functional component coronary stenosis (i.e., FFR) increases the discrimination for the risk of adverse events. The calculation of the SYNTAX score derived from non-invasive modalities such as coronary computed tomography angiography (CTA) has emerged as a mean to obtain the SYNTAX score before invasive cardiac catheterization...
April 2017: Cardiovascular Diagnosis and Therapy
https://www.readbyqxmd.com/read/28540209/myocardial-blood-flow-quantification-for-evaluation-of-coronary-artery-disease-by-computed-tomography
#8
REVIEW
Filippo Cademartiri, Sara Seitun, Alberto Clemente, Ludovico La Grutta, Patrizia Toia, Giuseppe Runza, Massimo Midiri, Erica Maffei
During the last decade coronary computed tomography angiography (CTA) has become the preeminent non-invasive imaging modality to detect coronary artery disease (CAD) with high accuracy. However, CTA has a limited value in assessing the hemodynamic significance of a given stenosis due to a modest specificity and positive predictive value. In recent years, different CT techniques for detecting myocardial ischemia have emerged, such as CT-derived fractional flow reserve (FFR-CT), transluminal attenuation gradient (TAG), and myocardial CT perfusion (CTP) imaging...
April 2017: Cardiovascular Diagnosis and Therapy
https://www.readbyqxmd.com/read/28540208/myocardial-ct-perfusion-imaging-for-ischemia-detection
#9
REVIEW
Patricia Carrascosa, Carlos Capunay
Coronary computed tomography angiography (CCTA) plays an important role in many specific scenarios such as in symptomatic patients with intermediate pretest of coronary artery disease (CAD), as well as in the triage of patients with acute chest pain with TIMI risk ≤2. However, it cannot detect the presence of associated ischemia, which is critical for clinical decision making among patients with moderate to severe stenosis. Although functional information can be obtained with different non-invasive tools, cardiac CT is the unique modality that can perform a comprehensive evaluation of coronary anatomy plus the functional significance of lesions...
April 2017: Cardiovascular Diagnosis and Therapy
https://www.readbyqxmd.com/read/28540071/ct-angio-for-the-evaluation-of-graft-patency
#10
REVIEW
Davide Di Lazzaro, Federico Crusco
Invasive coronary angiography (ICA) is the traditional method for the follow-up of graft patency in coronary artery bypass graft (CABG) patients. Nevertheless, the advent of multidetector computed tomography (MDCT) opened new perspectives for using a noninvasive, equally reliable method to study CABG patients. This review article will analyze the current feasibility of modern multi-slice MDCT, as well as its future perspectives.
April 2017: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/28539206/prediabetes-is-not-a-risk-factor-for-subclinical-coronary-atherosclerosis
#11
Gyung-Min Park, Young-Rak Cho, Seung-Whan Lee, Sung-Cheol Yun, Ki-Bum Won, Soe Hee Ann, Yong-Giun Kim, Shin-Jae Kim, Jae-Hyung Roh, Young-Hak Kim, Dong Hyun Yang, Joon-Won Kang, Tae-Hwan Lim, Chang Hee Jung, Eun Hee Koh, Woo Je Lee, Min-Seon Kim, Ki-Up Lee, Joong-Yeol Park, Hong-Kyu Kim, Jaewon Choe, Sang-Gon Lee
BACKGROUND: There are limited data regarding the influence of glycemic status on the risk of subclinical coronary atherosclerosis on coronary computed tomographic angiography (CCTA) in asymptomatic individuals. METHODS: We analyzed 6434 asymptomatic individuals who underwent CCTA. The degree and extent of subclinical coronary atherosclerosis were assessed by CCTA, and ≥50% diameter stenosis was defined as significant. Of study participants, 2197 (34.1%), 3122 (48...
May 19, 2017: International Journal of Cardiology
https://www.readbyqxmd.com/read/28533317/cardiovascular-toxicity-of-illicit-anabolic-androgenic-steroid-use
#12
Aaron L Baggish, Rory B Weiner, Gen Kanayama, James I Hudson, Michael T Lu, Udo Hoffmann, Harrison G Pope
BACKGROUND: Millions of individuals have used illicit anabolic-androgenic steroids (AAS), but the long-term cardiovascular associations of these drugs remain incompletely understood. METHODS: Using a cross-sectional cohort design, we recruited 140 experienced male weightlifters 34 to 54 years of age, comprising 86 men reporting ≥2 years of cumulative lifetime AAS use and 54 nonusing men. Using transthoracic echocardiography and coronary computed tomography angiography, we assessed 3 primary outcome measures: left ventricular (LV) systolic function (left ventricular ejection fraction), LV diastolic function (early relaxation velocity), and coronary atherosclerosis (coronary artery plaque volume)...
May 23, 2017: Circulation
https://www.readbyqxmd.com/read/28528881/impact-of-calcium-score-on-agreement-between-multidetector-computed-tomography-and-invasive-coronary-angiography
#13
José Alberto de Agustín, José Juan Gómez de Diego, Pedro Marcos-Alberca, Patricia Mahía, José Luis Rodrigo, María Luaces, Iván Javier Núñez-Gil, Joaquín Ferreiros, Ana Bustos, Beatriz Cabeza, Miguel Ángel García-Fernández, Carlos Macaya, Leopoldo Pérez de Isla
INTRODUCTION AND OBJECTIVES: Multidetector computed tomography (MDCT) has been demonstrated as a feasible alternative to invasive coronary angiography (ICA). However, contradictory results have been reported regarding the effect of coronary artery calcium score (CS) on the diagnostic accuracy of MDCT. Our aim was to assess the agreement of MDCT and ICA and to evaluate the influence of CS on this agreement. METHODS: We enrolled 266 consecutive patients who underwent evaluation with 64-slice MDCT and ICA...
May 18, 2017: Revista Española de Cardiología
https://www.readbyqxmd.com/read/28528743/-18-f-sodium-fluoride-positron-emission-tomography-for-molecular-imaging-of-coronary-atherosclerosis-based-on-computed-tomography-analysis
#14
Toshiro Kitagawa, Hideya Yamamoto, Shinya Toshimitsu, Ko Sasaki, Atsuhiro Senoo, Yumiko Kubo, Fuminari Tatsugami, Kazuo Awai, Yutaka Hirokawa, Yasuki Kihara
BACKGROUND AND AIMS: We aimed at evaluating the relation of (18)F-sodium fluoride ((18)F-NaF) uptake on positron emission tomography (PET) to coronary atherosclerosis detected and assessed by computed tomography (CT). METHODS: Thirty-two patients with one or more coronary atherosclerotic lesions detected on cardiac CT underwent (18)F-NaF PET/CT. Each coronary atherosclerotic lesion was evaluated on CT angiography for plaque types (calcified plaque [CP], non-calcified plaque [NCP], partially calcified plaque [PCP]), and the presence of CT-based high-risk features (minimum CT density <30 Hounsfield units and vascular remodeling index >1...
April 29, 2017: Atherosclerosis
https://www.readbyqxmd.com/read/28528430/risk-classification-of-highly-sensitive-troponin-i-predict-presence-of-vulnerable-plaque-assessed-by-dual-source-coronary-computed-tomography-angiography
#15
Ting Liu, Guan Wang, Peiling Li, Xu Dai
Patients presenting to the emergency department with acute chest pain, negative conventional troponin and electrocardiogram require serial testing to rule out acute coronary syndrome (ACS). We studied the association of highly sensitive troponin (hsTn) I with vulnerable plaque features as detected by coronary dual source computed tomography angiography (DSCTA) and determined whether hsTn I at the time of presentation combined with early DSCTA could improve classification of patients as high-risk or low risk for ACS...
May 20, 2017: International Journal of Cardiovascular Imaging
https://www.readbyqxmd.com/read/28528150/long-term-prognosis-of-patients-with-intramural-course-of-coronary-arteries-assessed-with-ct-angiography
#16
Aukelien C Dimitriu-Leen, Alexander R van Rosendael, Jeff M Smit, Tessa van Elst, Nan van Geloven, Teemu Maaniitty, J Wouter Jukema, Victoria Delgado, Arthur J H A Scholte, Antti Saraste, Juhani Knuuti, Jeroen J Bax
OBJECTIVES: The aim of the present study was to evaluate, in low-to-intermediate pre-test probability patients who were referred for coronary computed tomography angiography (CTA) and did not show obstructive coronary artery disease (CAD), whether an intramural course of a coronary artery is associated with worse outcome compared with patients without an intramural course of the coronary arteries. BACKGROUND: The prognostic value of an intramural course of the coronary arteries on coronary CTA in patients without obstructive CAD is not well-known...
May 11, 2017: JACC. Cardiovascular Imaging
https://www.readbyqxmd.com/read/28528146/prognostic-value-of-coronary-ct-angiography-with-selective-pet-perfusion-imaging-in-coronary-artery-disease
#17
Teemu Maaniitty, Iida Stenström, Jeroen J Bax, Valtteri Uusitalo, Heikki Ukkonen, Sami Kajander, Maija Mäki, Antti Saraste, Juhani Knuuti
OBJECTIVES: The purpose of this study was to evaluate the prognostic value of sequential hybrid imaging strategy in which positron emission tomography (PET) perfusion imaging is performed selectively in patients with suspected obstructive coronary artery disease (CAD) on coronary computed tomography angiography (CTA). BACKGROUND: Coronary CTA is an accurate diagnostic test for excluding obstructive CAD. However, the positive predictive value is suboptimal. METHODS: We investigated 864 consecutive symptomatic patients with intermediate probability of CAD who adhered to the sequential imaging approach...
May 15, 2017: JACC. Cardiovascular Imaging
https://www.readbyqxmd.com/read/28528054/surgical-management-of-simultaneous-left-coronary-atresia-and-anomalous-right-coronary-artery-origin
#18
Shyam Sathanandam, T K Susheel Kumar, Umar Boston, Christopher J Knott-Craig
A 9-year-old child presented with syncope during exercise. He received a diagnosis of congenital atresia of the left main coronary artery by angiography. He underwent successful coronary artery bypass grafting. On the third postoperative day, he experienced acute, precordial chest pain. An urgent computed tomographic scan showed an unrecognized anomalous origin of the right coronary artery (RCA) with a 1.5-cm intramural course. He was taken back to the operating room to undergo unroofing of the RCA. This case highlights the difficulty involved in making two rare diagnoses that can cause the same exact symptoms in a patient and the surgical challenges associated with it...
June 2017: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/28521653/matrix-metalloproteinase-3-gene-polymorphism-rs3025058-affects-markers-atherosclerosis-in-type-2-diabetes-mellitus
#19
Aleš Pleskovič, Marija Šantl Letonja, Andreja Cokan Vujkovac, Jovana Nikolajević Starčević, Martin Caprnda, Eduard Curilla, Ioana Mozos, Peter Kruzliak, Robert Prosecky, Daniel Petrovič
BACKGROUND: The study was designed to test the possible association between either polymorphisms of the matrix metalloproteinase-9 (MMP-9) gene (rs17576, rs3918242) or the MMP-3 5A/6A gene polymorphism (rs3025058) with markers of carotid atherosclerosis in patients with type 2 diabetes mellitus (T2DM). The second aim of the study was to demonstrate an association between either the rs17576, rs3918242 or rs3025058 and subclinical markers of coronary artery disease in the same subset of patients with T2DM...
May 19, 2017: VASA. Zeitschrift Für Gefässkrankheiten
https://www.readbyqxmd.com/read/28520537/anomalous-origin-of-right-coronary-artery-from-left-coronary-sinus-13-cases-treated-with-the-reimplantation-technique
#20
Alain Cubero, Alejandro Crespo, Gadah Hamzeh, Andrés Cortes, Daniel Rivas, José Ignacio Aramendi
OBJECTIVES: Anomalous aortic origin of a coronary artery is uncommon but potentially clinically significant. Manifestations vary from asymptomatic patients to those who present with angina pectoris, myocardial infarction, heart failure, syncope, arrhythmias, and sudden death. We describe our experience with surgical reimplantation and results at midterm follow-up. METHODS: Between February 2003 and July 2016, a total of 13 patients with anomalous origin of the right coronary artery (RCA) from the left sinus underwent surgical reimplantation...
May 2017: World Journal for Pediatric & Congenital Heart Surgery
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