Ioanna Saougou, Theodora E Markatseli, Charalampos Papagoras, Evripidis Kaltsonoudis, Paraskevi V Voulgari, Alexandros A Drosos
OBJECTIVES: The majority of patients with ankylosing spondylitis (AS) and psoriatic arthritis (PsA) are affected during their peak reproductive years. Tumor necrosis factor (TNF)α plays a pivotal role in the pathogenesis of both diseases. Today, anti-TNFα blockers are an essential treatment for these patients. To identify male patients who achieved pregnancy development during their management with anti-TNFα blockers (infliximab). METHODS: We reviewed the data of 65 patients with AS and 30 patients with PsA who were followed-up in our rheumatology outpatients clinic and they were on infliximab therapy between January 2001 and December 2010...
January 2013: Joint, Bone, Spine: Revue du Rhumatisme