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https://www.readbyqxmd.com/read/29334520/invited-commentary-evaluation-of-horner-syndrome-in-the-mri-era
#1
Aki Kawasaki
This Invited Commentary discusses the following article: BACKGROUND:: To identify the etiologies of adult Horner syndrome (HS) in the MRI era using a targeted evaluation approach and to assess the value and yield of targeted imaging. METHODS: A retrospective chart review was performed of 200 adult outpatients with HS, confirmed with cocaine eyedrop testing. Patients were divided into subgroups based on the presence or absence of symptoms and those who did or did not receive additional testing with hydroxyamphetamine drops...
January 11, 2018: Journal of Neuro-ophthalmology: the Official Journal of the North American Neuro-Ophthalmology Society
https://www.readbyqxmd.com/read/29334490/differential-impact-of-local-and-regional-aortic-stiffness-on-left-ventricular-remodeling-a-cardiovascular-magnetic-resonance-study
#2
Thiago Quinaglia, Mourad Z Bensalah, Emilie Bollache, Nadjia Kachenoura, Gilles Soulat, Pierre Boutouyrie, Stéphane Laurent, Elie Mousseaux
BACKGROUND: Left ventricular (LV) remodeling and aortic stiffness have independent predictive value for all causes and cardiovascular mortality. Because elastic properties of the arterial wall vary along the aortic pathway, we hypothesized that local and regional aortic stiffness could differently impact on LV remodeling. METHODS AND RESULTS: Regional aortic stiffness was determined from carotid-femoral pulse wave velocity (cfPWV) measured by aplanation tonometry...
January 13, 2018: Journal of Hypertension
https://www.readbyqxmd.com/read/29334265/prevalence-and-covariates-of-uncontrolled-hypertension-in-ischemic-stroke-survivors-the-norwegian-stroke-in-the-young-study
#3
Åshild Oftedal, Eva Gerdts, Ulrike Waje-Andreassen, Annette Fromm, Halvor Naess, Anja Linde, Sahrai Saeed
PURPOSE: Hypertension is the most important modifiable risk factor for stroke. Few data are available on control of hypertension in younger ischemic stroke survivors. MATERIAL AND METHODS: We assessed clinic and ambulatory blood pressure (BP) measurements in 320 patients aged 15-60 years (mean 48 ± 10) included in the Norwegian Stroke in the Young Study during 3-months follow-up after the index stroke. Controlled hypertension was defined as ambulatory BP <130/80 mmHg...
January 15, 2018: Blood Pressure
https://www.readbyqxmd.com/read/29329827/effect-of-serum-adiponectin-levels-on-the-association-between-childhood-body-mass-index-and-adulthood-carotid-intima-media-thickness
#4
Yang Du, Tao Zhang, Dianjianyi Sun, Changwei Li, Lydia Bazzano, Lu Qi, Marie Krousel-Wood, Jiang He, Paul K Whelton, Wei Chen, Shengxu Li
Childhood obesity predicts adult cardiovascular risk. We hypothesized that the association between childhood body mass index (BMI) and adult carotid intima-media thickness (CIMT) may be modified by levels of adiponectin, an adipocytokine that connects body fatness with cardiovascular risk. The study sample included 1,052 adults (71% white and 29% black, 57% female) aged 23.8 to 43.5 years who were previously examined as children in the Bogalusa Heart Study cohort, with an average follow-up period of 26.5 (range 14...
December 12, 2017: American Journal of Cardiology
https://www.readbyqxmd.com/read/29325542/visceral-adipose-tissue-and-carotid-intima-media-thickness-in-hiv-infected-patients-undergoing-cart-a-prospective-cohort-study
#5
Maria Teresa Beires, André Silva-Pinto, Ana Cristina Santos, António José Madureira, Jorge Pereira, Davide Carvalho, António Sarmento, Paula Freitas
BACKGROUND: Combined antiretroviral therapy (cART) in HIV-infected patients has been associated with lipodystrophy, metabolic abnormalities, and an increased risk of cardiovascular disease. Ultrasound measures of carotid artery intima-media thickness (cIMT) have been used as a valid measure of subclinical atherosclerosis and as a tool to predict the risk of cardiovascular events. Our aim was to evaluate the progression of cIMT in HIV-infected patients subjected to cART, with and without lipodystrophy, over a one-year period...
January 11, 2018: BMC Infectious Diseases
https://www.readbyqxmd.com/read/29325370/-association-between-carotid-artery-plaques-and-all-cause-mortality-and-cardiovascular-events
#6
W Li, F Ma, Y M Jiang, J J Li, L Song, S H Chen, X M Liu, X Q Li, S L Wu
Objective: To observe the association of carotid artery plaque with all-cause mortality and cardiovascular events. Methods: A total of 7 017 participants who completed the carotid sonography examination between 2010 and 2011 were selected from the stroke and the elderly prospective cohort Kailuan study. The participants of stroke cohort received health examination between 2006 and 2007, and participants of elderly cohort received health examination between 2010 and 2011. All participants were divided into plaque group (3 285 cases) and without plaque group (3 732 cases) according to with or without carotid artery plaque...
December 24, 2017: Zhonghua Xin Xue Guan Bing za Zhi
https://www.readbyqxmd.com/read/29323183/delivery-of-xenon-containing-echogenic-liposomes-inhibits-early-brain-injury-following-subarachnoid-hemorrhage
#7
Yi-Feng Miao, Tao Peng, Melanie R Moody, Melvin E Klegerman, Jaroslaw Aronowski, James Grotta, David D McPherson, Hyunggun Kim, Shao-Ling Huang
Xenon (Xe), a noble gas, has promising neuroprotective properties with no proven adverse side-effects. We evaluated neuroprotective effects of Xe delivered by Xe-containing echogenic liposomes (Xe-ELIP) via ultrasound-controlled cerebral drug release on early brain injury following subarachnoid hemorrhage (SAH). The Xe-ELIP structure was evaluated by ultrasound imaging, electron microscopy and gas chromatography-mass spectroscopy. Animals were randomly divided into five groups: Sham, SAH, SAH treated with Xe-ELIP, empty ELIP, or Xe-saturated saline...
January 11, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29316186/organ-damage-changes-in-patients-with-resistant-hypertension-randomized-to-renal-denervation-or-spironolactone-the-denervhta-denervaci%C3%A3-n-en-hipertensi%C3%A3-n-arterial-study
#8
Anna Oliveras, Pedro Armario, Laia Sans, Albert Clarà, Susana Vázquez, Luis Molina, Júlia Pareja, Alejandro de la Sierra, Julio Pascual
Renal denervation and spironolactone have both been proposed for the treatment of resistant hypertension, but their effects on preclinical target organ damage have not been compared. Twenty-four patients with 24-hour systolic blood pressure ≥140 mm Hg despite receiving three or more full-dose antihypertensive drugs, one a diuretic, were randomized to receive spironolactone or renal denervation. Changes in 24-hour blood pressure, urine albumin excretion, arterial stiffness, carotid intima-media thickness, and left ventricular mass index were evaluated at 6 months...
January 5, 2018: Journal of Clinical Hypertension
https://www.readbyqxmd.com/read/29310495/outcome-of-carotid-and-subclavian-blowout-syndrome-in-patients-with-pharynx-and-larynx-carcinoma-passing-a-standardized-multidisciplinary-treatment
#9
Constanze Gahleitner, Benedikt Hofauer, Katharina Storck, Andreas Knopf
BACKGROUND: Carotid blowout syndrome (CBS) is one of the most feared emergencies in the head and neck surgery and tends to occur in patients with head and neck cancer, wound complications, pharyngocutaneous fistulas, or after radio(chemo)therapy. CBS is always life threatening and associated with a 50% mortality/morbidity rate. METHODS: Between 2007 and 2015, a total of 51 patients who developed CBS caused by the tumour masses or after radio(chemo)therapy were included...
January 8, 2018: Acta Oto-laryngologica
https://www.readbyqxmd.com/read/29306901/cardiometabolic-health-among-adult-offspring-of-hypertensive-pregnancies-the-cardiovascular-risk-in-young-finns-study
#10
Robyn J Tapp, Alun D Hughes, Mika Kähönen, Tien Yin Wong, Nicholas Witt, Terho Lehtimäki, Nina Hutri-Kähönen, Pinki Sahota, Markus Juonala, Olli T Raitakari
BACKGROUND: Cardiometabolic health among adult offspring of hypertensive disorders of pregnancy (HDP) is relatively unknown. We hypothesized that offspring of HDP would have abnormalities in the retinal microvasculature and cardiac structure by midadulthood. METHODS AND RESULTS: The Cardiovascular Risk in Young Finns Study included randomly selected children from 5 Finnish university cities. The mean age of participants was 40 years (range 34-49 years) at the time of retinal photography and cardiac assessment...
January 6, 2018: Journal of the American Heart Association
https://www.readbyqxmd.com/read/29304064/hyperleptinemia-positively-associated-with-central-arterial-stiffness-in-hemodialysis-patients
#11
Chiu-Huang Kuo, Yu-Li Lin, Chung-Jen Lee, Chih-Hsien Wang, Yu-Hsien Lai, Hung-Hsiang Liou, Bang-Gee Hsu
OBJECTIVE: Leptin plays a role in stimulating vascular inflammation, vascular smooth muscle hypertrophy, and augmenting blood pressure, which contributes to the pathogenesis of atherosclerosis and leads to arterial stiffness. This vascular damage, measured by carotid-femoral pulse wave velocity (cfPWV), is recognized as an independent predictor of cardiovascular mortality in hemodialysis (HD) patients. The aim of this study was to evaluate the relationship between serum leptin and arterial stiffness in HD patients...
2018: PloS One
https://www.readbyqxmd.com/read/29303831/arterial-stiffness-and-peripheral-vascular-resistance-in-offspring-of-hypertensive-parents-influence-of-sex-and-other-confounders
#12
Niels Henrik Buus, Rasmus K Carlsen, Dinah S Khatir, Hans Eiskjær, Michael J Mulvany, Karin Skov
AIM: Established essential hypertension is associated with increased arterial stiffness and peripheral resistance, but the extent of vascular changes in persons genetically predisposed for essential hypertension is uncertain. METHODS: Participants from the Danish Hypertension Prevention Project (DHyPP) (both parents hypertensive) (n = 95, 41 ± 1 years, 53% men) were compared with available spouses (n = 45, 41 ± 1 years) using measurements of ambulatory blood pressure (BP), left ventricular mass index (LVMI), pulse wave velocity, central BP and augmentation index (AIx) in addition to forearm resting and minimal resistance [forearm resting vascular resistance (Rrest) and forearm minimal vascular resistance (Rmin)]...
January 4, 2018: Journal of Hypertension
https://www.readbyqxmd.com/read/29303699/implication-of-osteoprotegerin-and-sclerostin-in-axial-spondyloarthritis-cardiovascular-disease-study-of-163-spanish-patients
#13
Fernanda Genre, Javier Rueda-Gotor, Sara Remuzgo-Martínez, Alfonso Corrales, Begoña Ubilla, Verónica Mijares, Carlos Fernández-Díaz, Virginia Portilla, Ricardo Blanco, José Luis Hernández, Javier Llorca, Raquel López-Mejías, Miguel Angel González-Gay
OBJECTIVES: Due to the high incidence of cardiovascular disease in axial spondyloarthritis (axSpA), the search of potential biomarkers that may help to identify patients with high cardiovascular risk is of main importance. Therefore, in this study we assessed the implication of osteoprotegerin (OPG) and sclerostin (SCL), two biomarkers associated with cardiovascular disease and bone metabolism, in the clinical spectrum and atherosclerotic disease of patients with axSpA. METHODS: OPG and SCL serum levels were determined in 163 axSpA Spanish patients (119 ankylosing spondylitis and 44 non-radiographic axSpA) and 63 healthy controls by enzyme-linked immunosorbent assay...
December 15, 2017: Clinical and Experimental Rheumatology
https://www.readbyqxmd.com/read/29288784/association-of-prostatic-volume-and-carotid-intima-media-thickness-in-patients-with-benign-prostatic-hyperplasia
#14
Ali Riza Erbay, Hüseyin Ede, Kürsad Zengin, Mustafa Fatih Erkoc, Serhat Tanık, Sebahattin Albayrak, Ertan Yetkin
OBJECTIVE: To assess cardiovascular risk factors and carotid intima-media thickness in patients with benign prostatic hyperplasia. MATERIALS AND METHODS: One hundred and twenty three patients who were evaluated for the presence of benign prostatic hyperplasia with accompanying symptoms were included in the study. Patients were also examined by cardiology department to assess and measure cardiovascular risk factors, left ventricular functions and carotid intima-media thickness...
December 27, 2017: Urology
https://www.readbyqxmd.com/read/29285449/carotid-intima-medial-thickness-and-glucose-homeostasis-in-indian-obese-children-and-adolescents
#15
Aashima Dabas, Thushanth Thomas, Monita Gahlot, Nandita Gupta, K Devasenathipathy, Rajesh Khadgawat
Objective: To evaluate for subclinical atherosclerosis and its risk factors in Indian obese children. Materials and Methods: A cross-sectional, case-control study was conducted to recruit 80 children aged 6-17 years with constitutional obesity as cases and 23 age- and gender-matched controls with normal body mass index (BMI). Anthropometric and clinical evaluation was followed by biochemical analysis and body fat estimation by dual-energy X-ray absorptiometry in cases...
November 2017: Indian Journal of Endocrinology and Metabolism
https://www.readbyqxmd.com/read/29284736/carotid-atheroma-from-men-has-significantly-higher-levels-of-inflammation-and-iron-metabolism-enabled-by-macrophages
#16
Xi-Ming Yuan, Liam J Ward, Claes Forssell, Nabeel Siraj, Wei Li
BACKGROUND AND PURPOSE: Men differ from women in the manifestation of atherosclerosis and iron metabolism. Intraplaque hemorrhage and hemoglobin (Hb) catabolism by macrophages are associated with atherosclerotic lesion instability. The study aims were to investigate sex differences in (1) lesion severity in relation to blood Hb, (2) iron homeostasis in human carotid plaques, and (3) macrophage polarization within atheroma. METHODS: The carotid artery samples from 39 men and 23 women were immunostained with cell markers for macrophages, smooth muscle cells, ferritin, and TfR1 (transferrin receptor 1), which were further analyzed according to sex in relation to iron, Hb, and lipids in circulation...
December 28, 2017: Stroke; a Journal of Cerebral Circulation
https://www.readbyqxmd.com/read/29281076/impaired-baroreflex-sensitivity-carotid-stiffness-and-exaggerated-exercise-blood-pressure-a-community-based-analysis-from-the-paris-prospective-study-iii
#17
James E Sharman, Pierre Boutouyrie, Marie-Cécile Perier, Frédérique Thomas, Catherine Guibout, Hakim Khettab, Bruno Pannier, Stéphane Laurent, Xavier Jouven, Jean-Philippe Empana
Aims: People with exaggerated exercise blood pressure (BP) have adverse cardiovascular outcomes. Mechanisms are unknown but could be explained through impaired neural baroreflex sensitivity (BRS) and/or large artery stiffness. This study aimed to determine the associations of carotid BRS and carotid stiffness with exaggerated exercise BP. Methods and results: Blood pressure was recorded at rest and following an exercise step-test among 8976 adults aged 50 to 75 years from the Paris Prospective Study III...
December 21, 2017: European Heart Journal
https://www.readbyqxmd.com/read/29280189/adiponectin-concentration-data-improve-the-estimation-of-atherosclerotic-risk-in-normal-and-in-overweight-subjects
#18
Adriana Bertolami, José C de Lima-Júnior, Riobaldo M Cintra, Luiz S Carvalho, Carolina de C Gonzaga, Martha L Sulzbach, Ana C G P Petisco, José E M Barbosa, André A Faludi, Jorge Plutzky, Marcelo C Bertolami, Andrei C Sposito
BACKGROUND: The combinations of adipokines and body mass parameters to estimate carotid atherosclerotic disease have not been completely delineated. OBJECTIVE: To test the combinations of well-established, easily accessible body mass indices and circulating biomarkers to identify increased carotid intima-media thickness (cIMT) in a primary prevention setting. DESIGN AND PATIENTS: In a cross-sectional analysis of 339 asymptomatic individuals with no history of cardiovascular events, inflammatory and insulin sensitivity biomarkers as well as adipokine levels were measured and combined with body mass parameters to evaluate the best marker for increased cIMT...
December 27, 2017: Clinical Endocrinology
https://www.readbyqxmd.com/read/29280026/management-of-non-functioning-pituitary-adenomas-surgery
#19
REVIEW
David L Penn, William T Burke, Edward R Laws
Non-functional pituitary adenomas (NFPAs) are benign tumors of the pituitary gland that do not over-secrete hormonal products, therefore, they are generally detected through symptoms of mass effect, including headache, vision loss, or hypopituitarism. There are multiple pathological subtypes of NFPAs, such as null cell adenomas, silent gonadotrophs, silent somatotrophs, silent corticotrophs, and silent subtype 3, all of which can be classified based on immunohistochemical studies and electron microscopy. Despite these numerous pathological subtypes, surgical resection remains the first-line treatment for NFPAs...
December 26, 2017: Pituitary
https://www.readbyqxmd.com/read/29279983/surgical-anatomy-of-neurovascular-structures-related-to-ventral-c1-2-complex-an-anatomical-study
#20
Sibel Cirpan, Salih Sayhan, Goksin Nilufer Yonguc, Canan Eyuboglu, Mustafa Güvençer, Sait Naderi
OBJECTIVE: Transoral odontoidectomy and ventral C1-2 stabilization are important surgical procedures, performed to decompress ventral spinal cord, and to stabilize craniovertebral junction. These procedures require knowledge regarding surgical anatomy of neurovascular structures ventral to the C1-2 complex. The aim of this study is to evaluate the relationships between neurovascular structures and bony landmarks in ventral atlantoaxial complex. MATERIALS AND METHODS: This study was performed on six formaldehyde fixed cadaveric head and neck specimens...
December 26, 2017: Surgical and Radiologic Anatomy: SRA
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