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https://www.readbyqxmd.com/read/28098514/edible-and-medicinal-mushrooms-emerging-brain-food-for-the-mitigation-of-neurodegenerative-diseases
#1
Chia-Wei Phan, Pamela David, Vikineswary Sabaratnam
There is an exponential increase in dementia in old age at a global level because of increasing life expectancy. The prevalence of neurodegenerative diseases such as dementia and Alzheimer's disease (AD) will continue to rise steadily, and is expected to reach 42 million cases worldwide in 2020. Despite the advancement of medication, the management of these diseases remains largely ineffective. Therefore, it is vital to explore novel nature-based nutraceuticals to mitigate AD and other age-related neurodegenerative disorders...
January 2017: Journal of Medicinal Food
https://www.readbyqxmd.com/read/28093222/swainsonine-induced-lysosomal-storage-disease-in-goats-caused-by-the-ingestion-of-sida-rodrigoi-monteiro-in-north-western-argentina
#2
Juan Francisco Micheloud, Raúl Marin, Luis Adrian Colque-Caro, Olga Gladys Martínez, Dale Gardner, Eduardo Juan Gimeno
There are numerous poisonous plants that can induce intralysosomal accumulation of glycoproteins and neurologic syndromes. Here we describe for the first time, a disease caused by ingesting Sida rodrigoi Monteiro in goats in North-western Argentina. The animals showed weight loss, indifference to the environment, unsteady gait and ataxia. Histopathologic studies showed vacuolization in cells of various organs, mainly in the CNS. The material deposited in the cells was positive for LCA (Lens culinaris agglutinin), WGA (Triticum vulgaris agglutinin), sWGA (succinyl-Triticum vulgaris agglutinin) and Con-A (Concanavalia ensiformis agglutinin) lectins...
January 13, 2017: Toxicon: Official Journal of the International Society on Toxinology
https://www.readbyqxmd.com/read/28090266/reconstruction-of-a-composite-comparative-map-composed-of-ten-legume-genomes
#3
Chaeyoung Lee, Dongwoon Yu, Hong-Kyu Choi, Ryan W Kim
The Fabaceae (legume family) is the third largest and the second of agricultural importance among flowering plant groups. In this study, we report the reconstruction of a composite comparative map composed of ten legume genomes, including seven species from the galegoid clade (Medicago truncatula, Medicago sativa, Lens culinaris, Pisum sativum, Lotus japonicus, Cicer arietinum, Vicia faba) and three species from the phaseoloid clade (Vigna radiata, Phaseolus vulgaris, Glycine max). To accomplish this comparison, a total of 209 cross-species gene-derived markers were employed...
2017: Genes & Genomics
https://www.readbyqxmd.com/read/28086773/pleurotus-giganteus-berk-karun-hyde-the-giant-oyster-mushroom-inhibits-no-production-in-lps-h2o2-stimulated-raw-264-7-cells-via-stat-3-and-cox-2-pathways
#4
Asweni Baskaran, Kek Heng Chua, Vikineswary Sabaratnam, Mani Ravishankar Ram, Umah Rani Kuppusamy
BACKGROUND: Pleurotus giganteus (Berk. Karunarathna and K.D. Hyde), has been used as a culinary mushroom and is known to have medicinal properties but its potential as an anti-inflammatory agent to mitigate inflammation triggered diseases is untapped. In this study, the molecular mechanism underlying the protective effect of ethanol extract of P. giganteus (EPG) against lipopolysaccharide (LPS) and combination of LPS and hydrogen peroxide (H2O2)-induced inflammation on RAW 264.7 macrophages was investigated...
January 13, 2017: BMC Complementary and Alternative Medicine
https://www.readbyqxmd.com/read/28078243/ethnobotanical-knowledge-of-apiaceae-family-in-iran-a-review
#5
REVIEW
Mohammad Sadegh Amiri, Mohammad Reza Joharchi
OBJECTIVE: Apiaceae (Umbelliferae) family is one of the biggest plant families on the earth. Iran has a huge diversity of Apiaceae members. This family possesses a range of compounds that have many biological activities. The members of this family are well known as vegetables, culinary and medicinal plants. Here, we present a review of ethnobotanical uses of Apiaceae plants by the Iranian people in order to provide a comprehensive documentation for future investigations. MATERIALS AND METHODS: We checked scientific studies published in books and journals in various electronic databases (Medline, PubMed, Science Direct, Scopus and Google Scholar websites) from 1937 to 2015 and reviewed a total of 52 publications that provided information about different applications of these plant species in human and livestock...
November 2016: Avicenna Journal of Phytomedicine
https://www.readbyqxmd.com/read/28070488/transcriptome-profiling-of-elettaria-cardamomum-l-maton-small-cardamom
#6
F Nadiya, N Anjali, Jinu Thomas, A Gangaprasad, K K Sabu
Elettaria cardamomum (L.) Maton, known as 'queen of spices, is a perennial herbaceous monocot of the family Zingiberaceae, native to southern India. Cardamom is an economically valuable spice crop and used widely in culinary and medicinal purposes. In the present study, using Ion Proton RNA sequencing technology, we performed transcriptome sequencing and de novo transcriptome assembly of a wild and five cultivar genotypes of cardamom. RNA-seq generated a total of 22,811,983 (92 base) and 24,889,197 (75 base) raw reads accounting for approximately 8...
March 2017: Genomics Data
https://www.readbyqxmd.com/read/28054232/retraction-note-to-coordinated-response-of-sulfate-transport-cysteine-biosynthesis-and-glutathione-mediated-antioxidant-defense-in-lentil-lens-culinaris-medik-genotypes-exposed-to-arsenic
#7
https://www.readbyqxmd.com/read/28029136/application-of-lectin-array-technology-for-biobetter-characterization-its-correlation-with-fc%C3%AE-riii-binding-and-adcc
#8
Markus Roucka, Klaus Zimmermann, Markus Fido, Andreas Nechansky
Lectin microarray technology was applied to compare the glycosylation pattern of the monoclonal antibody MB311 expressed in SP2.0 cells to an antibody-dependent cellular cytotoxic effector function (ADCC)-optimized variant (MB314). MB314 was generated by a plant expression system that uses genetically modified moss protoplasts (Physcomitrella patens) to generate a de-fucosylated version of MB311. In contrast to MB311, no or very low interactions of MB314 with lectins Aspergillus oryzae l-fucose (AOL), Pisum sativum agglutinin (PSA), Lens culinaris agglutinin (LCA), and Aleuria aurantia lectin (AAL) were observed...
December 24, 2016: Microarrays
https://www.readbyqxmd.com/read/28009867/essential-oils-of-three-cow-parsnips-composition-and-activity-against-nosocomial-and-foodborne-pathogens-and-food-contaminants
#9
Ljuboš Ušjak, Silvana Petrović, Milica Drobac, Marina Soković, Tatjana Stanojković, Ana Ćirić, Marjan Niketić
Although some widespread, native cow parsnips (Heracleum L. spp., Apiaceae) had broad medicinal and culinary applications throughout history, the knowledge about their volatile constituents is insufficient. This work investigates the composition and bioactivities of H. sphondylium L. (HSPH), H. sibiricum L. (HSIB) and H. montanum Schleich. ex Gaudin (HMON) essential oils. The composition was tested by GC and GC-MS. (Z)-β-Ocimene was the most abundant in HSPH (28.9%) and HMON (20.4%) root oils, while in HSIB root oil, β-pinene (26...
December 23, 2016: Food & Function
https://www.readbyqxmd.com/read/28008812/anti-inflammation-properties-of-fruiting-bodies-and-submerged-cultured-mycelia-of-culinary-medicinal-higher-basidiomycetes-mushrooms
#10
Rao-Chi Chien, Lan-Min Lin, Yuan-Hua Chang, Yu-Chieh Lin, Pei-Hsuan Wu, Mikheil D Asatiani, Sophie-Gabrielle Wasser, Maxim Krakhmalnyi, Abed Agbarya, Solomon P Wasser, Jeng-Leun Mau
This research shows the phenolic composition and anti-inflammation properties of fruiting bodies and mycelia of 15 strains of 12 species of higher Basidiomycetes medicinal mushrooms. In this research, 15 extracts were prepared and their effects on inflammation-related mediators in RAW 264.7 cells were evaluated. In the extracts, amounts of total phenols ranged from 8.47 to 70.32 gallic acid equivalents mg/g and amounts of flavonoids ranged from 0.13 to 15.21 rutin equivalents mg/g. The production of nitric oxide, tumor necrosis factor-α, and interleukin-6 was decreased at different levels by these extracts, whereas the production of interleukin-10 was increased by 6 of the extracts...
2016: International Journal of Medicinal Mushrooms
https://www.readbyqxmd.com/read/28008810/a-polysaccharide-from-the-culinary-medicinal-mushroom-pholiota-nameko-agaricomycetes-inhibits-the-nf-%C3%AE%C2%BAb-pathway-in-dendritic-cells-through-the-tlr2-receptor
#11
Haiping Li, Pei Zhao, Fengling Wang, Lihua Huai, Ruixuan Zhu, Guoliang Li, Yufeng Xu
A polysaccharide purified from Pholiota nameko (PNPS-1) was found to have anticancer and anti-inflammatory activity. This study investigated the effect of PNPS-1 on the nuclear factor (NF)-κB signaling pathway of TLR2 small interfering RNA-silenced murine bone marrow-derived dendritic cells (BMDCs) and relevant mechanisms. The expression of messenger RNA of 4 NF-κB-related genes, including MyD88, IKBKB, RelA(p65), and CCL2, was determined by real-time polymerase chain reaction; the expression of the phenotype molecule intercellular adhesion molecule-1 (ICAM-1) by flow cytometry; the protein expression of IKKβ and p65 by Western blot; the production of p65 by enzyme-linked immunosorbent assay; and the expression of p65 by immunocytochemistry...
2016: International Journal of Medicinal Mushrooms
https://www.readbyqxmd.com/read/28004742/first-molecular-and-isotopic-evidence-of-millet-processing-in-prehistoric-pottery-vessels
#12
Carl Heron, Shinya Shoda, Adrià Breu Barcons, Janusz Czebreszuk, Yvette Eley, Marise Gorton, Wiebke Kirleis, Jutta Kneisel, Alexandre Lucquin, Johannes Müller, Yastami Nishida, Joon-Ho Son, Oliver E Craig
Analysis of organic residues in pottery vessels has been successful in detecting a range of animal and plant products as indicators of food preparation and consumption in the past. However, the identification of plant remains, especially grain crops in pottery, has proved elusive. Extending the spectrum is highly desirable, not only to strengthen our understanding of the dispersal of crops from centres of domestication but also to determine modes of food processing, artefact function and the culinary significance of the crop...
December 22, 2016: Scientific Reports
https://www.readbyqxmd.com/read/28003804/golden-needle-mushroom-a-culinary-medicine-with-evidenced-based-biological-activities-and-health-promoting-properties
#13
REVIEW
Calyn Tang, Pearl Ching-Xin Hoo, Loh Teng-Hern Tan, Priyia Pusparajah, Tahir Mehmood Khan, Learn-Han Lee, Bey-Hing Goh, Kok-Gan Chan
Flammulina velutipes (enoki, velvet shank, golden needle mushroom or winter mushroom), one of the main edible mushrooms on the market, has long been recognized for its nutritional value and delicious taste. In recent decades, research has expanded beyond detailing its nutritional composition and delved into the biological activities and potential health benefits of its constituents. Many bioactive constituents from a range of families have been isolated from different parts of the mushroom, including carbohydrates, protein, lipids, glycoproteins, phenols, and sesquiterpenes...
2016: Frontiers in Pharmacology
https://www.readbyqxmd.com/read/27991959/local-anesthetic-activity-from-extracts-fractions-and-pure-compounds-from-the-roots-of-ottonia-anisum-spreng-piperaceae
#14
Kelvin S E López, André M Marques, Davyson DE L Moreira, Leosvaldo S Velozo, Roberto T Sudo, Gisele Zapata-Sudo, Elsie F Guimarães, Maria Auxiliadora C Kaplan
Piperaceae species can be found worldwide in tropical and subtropical areas and many of them have been used for centuries in traditional folk medicine and in culinary. In Brazil, species of Piperaceae are commonly used in some communities as local anesthetic and analgesic. Countrified communities have known some species of the genus Ottonia as "anestesia" and it is a common habit of chewing leaves and roots of Ottonia species to relief toothache. The purpose of this study is to report our findings on new molecules entities obtained from the roots of Ottonia anisum Spreng, in which local anesthetic activity (sensory blockage) is demonstrated for the first time in vivo guinea pig model...
October 2016: Anais da Academia Brasileira de Ciências
https://www.readbyqxmd.com/read/27989856/development-of-oral-site-specific-pellets-containing-flavonoid-extract-with-antioxidant-activity
#15
Zsófia Edit Pápay, Nikolett Kállai-Szabó, Krisztina Ludányi, Imre Klebovich, István Antal
Herbal medicines are recognized as an effective treatment of common diseases, mainly associated with oxidative stress. Therefore developing drug delivery systems of these biological active ingredients are gaining interest. Parsley (Petroselinum crispum L.) is a well-known culinary herb and its leaf contains high amount of apigenin, therefore it is suitable as a natural source of this flavonoid. Apigenin possess many health effects such as antioxidant, anti-inflammatory and anticancer activities. Unfortunately, these benefits are limited due to the low water solubility and bioavailability, it was recently classified as BCS II group compound...
October 29, 2016: European Journal of Pharmaceutical Sciences
https://www.readbyqxmd.com/read/27979078/cooking-impact-in-color-pigments-and-volatile-composition-of-grapevine-leaves-vitis-vinifera-l-var-malvasia-fina-and-touriga-franca
#16
Adriano Lima, José Alberto Pereira, Ilton Baraldi, Ricardo Malheiro
Grapevine leaves (Vitis vinifera L. var. Malvasia Fina and Touriga Franca) under culinary treatment (blanching and boiling at 60, 75 and 90min) were studied for their color, pigments and volatile fraction changes. Blanching and boiling caused a decrease in luminosity and a loss of green coloration in both varieties, while a yellow-brownish color arose. Significant correlations were established between the loss of green color (monochromatic variable a(∗)) and the total chlorophylls content. The main volatiles in fresh leaves [(Z)-3-hexenal, (Z)-3-hexen-1-ol, and (Z)-3-hexenyl acetate] were drastically reduced by blanching and suppressed by boiling...
April 15, 2017: Food Chemistry
https://www.readbyqxmd.com/read/27976467/rapid-species-level-identification-of-salvias-by-chemometric-processing-of-ambient-ionisation-mass-spectrometry-derived-chemical-profiles
#17
Justine E Giffen, Ashton D Lesiak, A John Dane, Robert B Cody, Rabi A Musah
INTRODUCTION: The Salvia genus contains numerous economically important plants that have horticultural, culinary and nutraceutical uses. They are often similar in appearance, making species determination difficult. Species identification of dried Salvia products is also challenging since distinguishing plant morphological features are no longer present. OBJECTIVE: The development of a simple high-throughput method of analysis of fresh and dried Salvia leaves that would permit rapid species-level identification and detection of diagnostic biomarkers...
January 2017: Phytochemical Analysis: PCA
https://www.readbyqxmd.com/read/27976376/italian-and-spanish-commercial-tomato-sauces-for-pasta-dressing-study-of-sensory-and-head-space-profiles-by-flash-profiling-and-spme-gc-ms
#18
Alessandra Bendini, Anna Vallverdu-Queralt, Enrico Valli, Rosa Palagano, Rosa Maria Lamuela-Raventos, Tullia Gallina Toschi
BACKGROUND: The sensory and head-space profiles of Italian and Spanish commercial tomato sauces have been studied. The Flash Profiling method was used to evaluate the sensory characteristics and samples within each set and were ranked according to selected descriptors. A hundred volatile compounds were identified by SPME-GC-MS. RESULTS: For Italian samples, the sensory notes of basil/aromatic herbs, acid and cooked tomato were among the most perceived by assessors, whereas in Spanish ones the sensory attributes of garlic/onion, onion/sweet pepper and, as for the Italian ones, cooked tomato were among the most frequently found...
December 15, 2016: Journal of the Science of Food and Agriculture
https://www.readbyqxmd.com/read/27965963/transforming-beef-by-products-into-valuable-ingredients-which-spell-recipe-to-use
#19
Maeve Henchion, Mary McCarthy, Jim O'Callaghan
Satisfying the increasing global demand for protein results in challenges from a supply perspective. Increased use of animal proteins, through greater use of meat by-products, could form part of the solution, subject to consumer acceptance. This research investigates consumer evaluations of food products that incorporate ingredients derived from offals that have been produced through a range of food processing technologies. Using focus groups incorporating product stimuli representing various combinations of offals, processing, and carrier products, the research finds that the physical state and perceived naturalness of the ingredients influences acceptance...
2016: Frontiers in Nutrition
https://www.readbyqxmd.com/read/27965082/analysis-of-whole-chloroplast-genomes-from-the-genera-of-the-clauseneae-the-curry-tribe-rutaceae-citrus-family
#20
Vikram S Shivakumar, Marc S Appelhans, Gabriel Johnson, Monica Carlsen, Elizabeth A Zimmer
The Clauseneae (Aurantioideae, Rutaceae) is a tribe in the Citrus family that, although economically important as it contains the culinary and medicinally-useful curry tree (Bergera koenigii), has been relatively understudied. Due to the recent significant taxonomic changes made to this tribe, a closer inspection of the genetic relationships among its genera has been warranted. Whole genome skimming was used to generate chloroplast genomes from six species, representing each of the four genera (Bergera, Clausena, Glycosmis, Micromelum) in the Clauseneae tribe plus one closely related outgroup (Merrillia), using the published plastome sequence of Citrus sinensis as a reference...
December 11, 2016: Molecular Phylogenetics and Evolution
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