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https://www.readbyqxmd.com/read/28086773/pleurotus-giganteus-berk-karun-hyde-the-giant-oyster-mushroom-inhibits-no-production-in-lps-h2o2-stimulated-raw-264-7-cells-via-stat-3-and-cox-2-pathways
#1
Asweni Baskaran, Kek Heng Chua, Vikineswary Sabaratnam, Mani Ravishankar Ram, Umah Rani Kuppusamy
BACKGROUND: Pleurotus giganteus (Berk. Karunarathna and K.D. Hyde), has been used as a culinary mushroom and is known to have medicinal properties but its potential as an anti-inflammatory agent to mitigate inflammation triggered diseases is untapped. In this study, the molecular mechanism underlying the protective effect of ethanol extract of P. giganteus (EPG) against lipopolysaccharide (LPS) and combination of LPS and hydrogen peroxide (H2O2)-induced inflammation on RAW 264.7 macrophages was investigated...
January 13, 2017: BMC Complementary and Alternative Medicine
https://www.readbyqxmd.com/read/28078243/ethnobotanical-knowledge-of-apiaceae-family-in-iran-a-review
#2
REVIEW
Mohammad Sadegh Amiri, Mohammad Reza Joharchi
OBJECTIVE: Apiaceae (Umbelliferae) family is one of the biggest plant families on the earth. Iran has a huge diversity of Apiaceae members. This family possesses a range of compounds that have many biological activities. The members of this family are well known as vegetables, culinary and medicinal plants. Here, we present a review of ethnobotanical uses of Apiaceae plants by the Iranian people in order to provide a comprehensive documentation for future investigations. MATERIALS AND METHODS: We checked scientific studies published in books and journals in various electronic databases (Medline, PubMed, Science Direct, Scopus and Google Scholar websites) from 1937 to 2015 and reviewed a total of 52 publications that provided information about different applications of these plant species in human and livestock...
November 2016: Avicenna Journal of Phytomedicine
https://www.readbyqxmd.com/read/28070488/transcriptome-profiling-of-elettaria-cardamomum-l-maton-small-cardamom
#3
F Nadiya, N Anjali, Jinu Thomas, A Gangaprasad, K K Sabu
Elettaria cardamomum (L.) Maton, known as 'queen of spices, is a perennial herbaceous monocot of the family Zingiberaceae, native to southern India. Cardamom is an economically valuable spice crop and used widely in culinary and medicinal purposes. In the present study, using Ion Proton RNA sequencing technology, we performed transcriptome sequencing and de novo transcriptome assembly of a wild and five cultivar genotypes of cardamom. RNA-seq generated a total of 22,811,983 (92 base) and 24,889,197 (75 base) raw reads accounting for approximately 8...
March 2017: Genomics Data
https://www.readbyqxmd.com/read/28009867/essential-oils-of-three-cow-parsnips-composition-and-activity-against-nosocomial-and-foodborne-pathogens-and-food-contaminants
#4
Ljuboš Ušjak, Silvana Petrović, Milica Drobac, Marina Soković, Tatjana Stanojković, Ana Ćirić, Marjan Niketić
Although some widespread, native cow parsnips (Heracleum L. spp., Apiaceae) had broad medicinal and culinary applications throughout history, the knowledge about their volatile constituents is insufficient. This work investigates the composition and bioactivities of H. sphondylium L. (HSPH), H. sibiricum L. (HSIB) and H. montanum Schleich. ex Gaudin (HMON) essential oils. The composition was tested by GC and GC-MS. (Z)-β-Ocimene was the most abundant in HSPH (28.9%) and HMON (20.4%) root oils, while in HSIB root oil, β-pinene (26...
December 23, 2016: Food & Function
https://www.readbyqxmd.com/read/28008812/anti-inflammation-properties-of-fruiting-bodies-and-submerged-cultured-mycelia-of-culinary-medicinal-higher-basidiomycetes-mushrooms
#5
Rao-Chi Chien, Lan-Min Lin, Yuan-Hua Chang, Yu-Chieh Lin, Pei-Hsuan Wu, Mikheil D Asatiani, Sophie-Gabrielle Wasser, Maxim Krakhmalnyi, Abed Agbarya, Solomon P Wasser, Jeng-Leun Mau
This research shows the phenolic composition and anti-inflammation properties of fruiting bodies and mycelia of 15 strains of 12 species of higher Basidiomycetes medicinal mushrooms. In this research, 15 extracts were prepared and their effects on inflammation-related mediators in RAW 264.7 cells were evaluated. In the extracts, amounts of total phenols ranged from 8.47 to 70.32 gallic acid equivalents mg/g and amounts of flavonoids ranged from 0.13 to 15.21 rutin equivalents mg/g. The production of nitric oxide, tumor necrosis factor-α, and interleukin-6 was decreased at different levels by these extracts, whereas the production of interleukin-10 was increased by 6 of the extracts...
2016: International Journal of Medicinal Mushrooms
https://www.readbyqxmd.com/read/28008810/a-polysaccharide-from-the-culinary-medicinal-mushroom-pholiota-nameko-agaricomycetes-inhibits-the-nf-%C3%AE%C2%BAb-pathway-in-dendritic-cells-through-the-tlr2-receptor
#6
Haiping Li, Pei Zhao, Fengling Wang, Lihua Huai, Ruixuan Zhu, Guoliang Li, Yufeng Xu
A polysaccharide purified from Pholiota nameko (PNPS-1) was found to have anticancer and anti-inflammatory activity. This study investigated the effect of PNPS-1 on the nuclear factor (NF)-κB signaling pathway of TLR2 small interfering RNA-silenced murine bone marrow-derived dendritic cells (BMDCs) and relevant mechanisms. The expression of messenger RNA of 4 NF-κB-related genes, including MyD88, IKBKB, RelA(p65), and CCL2, was determined by real-time polymerase chain reaction; the expression of the phenotype molecule intercellular adhesion molecule-1 (ICAM-1) by flow cytometry; the protein expression of IKKβ and p65 by Western blot; the production of p65 by enzyme-linked immunosorbent assay; and the expression of p65 by immunocytochemistry...
2016: International Journal of Medicinal Mushrooms
https://www.readbyqxmd.com/read/28003804/golden-needle-mushroom-a-culinary-medicine-with-evidenced-based-biological-activities-and-health-promoting-properties
#7
REVIEW
Calyn Tang, Pearl Ching-Xin Hoo, Loh Teng-Hern Tan, Priyia Pusparajah, Tahir Mehmood Khan, Learn-Han Lee, Bey-Hing Goh, Kok-Gan Chan
Flammulina velutipes (enoki, velvet shank, golden needle mushroom or winter mushroom), one of the main edible mushrooms on the market, has long been recognized for its nutritional value and delicious taste. In recent decades, research has expanded beyond detailing its nutritional composition and delved into the biological activities and potential health benefits of its constituents. Many bioactive constituents from a range of families have been isolated from different parts of the mushroom, including carbohydrates, protein, lipids, glycoproteins, phenols, and sesquiterpenes...
2016: Frontiers in Pharmacology
https://www.readbyqxmd.com/read/27991959/local-anesthetic-activity-from-extracts-fractions-and-pure-compounds-from-the-roots-of-ottonia-anisum-spreng-piperaceae
#8
Kelvin S E López, André M Marques, Davyson DE L Moreira, Leosvaldo S Velozo, Roberto T Sudo, Gisele Zapata-Sudo, Elsie F Guimarães, Maria Auxiliadora C Kaplan
Piperaceae species can be found worldwide in tropical and subtropical areas and many of them have been used for centuries in traditional folk medicine and in culinary. In Brazil, species of Piperaceae are commonly used in some communities as local anesthetic and analgesic. Countrified communities have known some species of the genus Ottonia as "anestesia" and it is a common habit of chewing leaves and roots of Ottonia species to relief toothache. The purpose of this study is to report our findings on new molecules entities obtained from the roots of Ottonia anisum Spreng, in which local anesthetic activity (sensory blockage) is demonstrated for the first time in vivo guinea pig model...
October 2016: Anais da Academia Brasileira de Ciências
https://www.readbyqxmd.com/read/27989856/development-of-oral-site-specific-pellets-containing-flavonoid-extract-with-antioxidant-activity
#9
Zsófia Edit Pápay, Nikolett Kállai-Szabó, Krisztina Ludányi, Imre Klebovich, István Antal
Herbal medicines are recognized as an effective treatment of common diseases, mainly associated with oxidative stress. Therefore developing drug delivery systems of these biological active ingredients are gaining interest. Parsley (Petroselinum crispum L.) is a well-known culinary herb and its leaf contains high amount of apigenin, therefore it is suitable as a natural source of this flavonoid. Apigenin possess many health effects such as antioxidant, anti-inflammatory and anticancer activities. Unfortunately, these benefits are limited due to the low water solubility and bioavailability, it was recently classified as BCS II group compound...
October 29, 2016: European Journal of Pharmaceutical Sciences
https://www.readbyqxmd.com/read/27965082/analysis-of-whole-chloroplast-genomes-from-the-genera-of-the-clauseneae-the-curry-tribe-rutaceae-citrus-family
#10
Vikram S Shivakumar, Marc S Appelhans, Gabriel Johnson, Monica Carlsen, Elizabeth A Zimmer
The Clauseneae (Aurantioideae, Rutaceae) is a tribe in the Citrus family that, although economically important as it contains the culinary and medicinally-useful curry tree (Bergera koenigii), has been relatively understudied. Due to the recent significant taxonomic changes made to this tribe, a closer inspection of the genetic relationships among its genera has been warranted. Whole genome skimming was used to generate chloroplast genomes from six species, representing each of the four genera (Bergera, Clausena, Glycosmis, Micromelum) in the Clauseneae tribe plus one closely related outgroup (Merrillia), using the published plastome sequence of Citrus sinensis as a reference...
December 11, 2016: Molecular Phylogenetics and Evolution
https://www.readbyqxmd.com/read/27924631/cardioprotective-effects-of-curcumin-loaded-magnetic-hydrogel-nanocomposite-nanocurcumin-against-doxorubicin-induced-cardiac-toxicity-in-rat-cardiomyocyte-cell-lines
#11
Mehrdad Namdari, Ali Eatemadi
Curcumin, is a yellow substance extracted from Curcuma longa rhizomes, it is a crystalline compound that has been traditionally applied in culinary practices and medicines in India. The aim of our study is to demonstrate the efficacy of curcumin-loaded magnetic hydrogel nanocomposite in the treatment of heart hypertrophy. 10 rats weighing 150-200 g each were induced with heart failure using 2.5 mg/kg doxorubicin for 2 weeks. The test groups were treated with curcumin-loaded magnetic hydrogel nanocomposite while the control was treated with curcumin alone...
December 7, 2016: Artificial Cells, Nanomedicine, and Biotechnology
https://www.readbyqxmd.com/read/27910787/nonvolatile-taste-components-and-antioxidant-properties-of-fruiting-body-and-mycelium-with-high-ergothioneine-content-from-the-culinary-medicinal-golden-oyster-mushroom-pleurotus-citrinopileatus-agaricomycetes
#12
Shin-Yi Lin, Shih-Chang Chien, Sheng-Yang Wang, Jeng-Leun Mau
Pleurotus citrinopileatus mycelium was prepared with high ergothioneine (Hi-Ergo) content and its proximate composition, nonvolatile taste components, and antioxidant properties were studied. The ergothioneine contents of fruiting bodies and Hi-Ergo and regular mycelia were 3.89, 14.57, and 0.37 mg/g dry weight, respectively. Hi-Ergo mycelium contained more dietary fiber, soluble polysaccharides, and ash but less carbohydrates, reducing sugar, fiber, and fat than regular mycelium. However, Hi-Ergo mycelium contained the smallest amounts of total sugars and polyols (47...
2016: International Journal of Medicinal Mushrooms
https://www.readbyqxmd.com/read/27910786/bioavailability-and-digestibility-of-nutrients-from-the-dried-oyster-culinary-medicinal-mushroom-pleurotus-ostreatus-agaricomycetes-in-vivo-experiments
#13
Julita Regula, Joanna Suliburska, Marek Siwulski
There is a limited number of publications on the bioavailability and digestibility of nutrients contained in macrofungi. The aim of this study was to assess the bioavailability and digestibility of macronutrients using in vivo experiments on laboratory animals. The experiments were conducted with the commercial oyster mushroom Pleurotus ostreatus. Semisynthetic diets were prepared based on the modified AIN-93M diet and were supplemented with 4% and 8% mushroom powder. Between days 4 and 13, apparent digestibility indexes were determined for all animals using the conventional balance method...
2016: International Journal of Medicinal Mushrooms
https://www.readbyqxmd.com/read/27910772/structural-characterization-and-immunological-activities-of-a-novel-water-soluble-polysaccharide-from-the-fruiting-bodies-of-culinary-medicinal-winter-mushroom-flammulina-velutipes-agaricomycetes
#14
Ting Feng, Wei Jia, Wen-Han Wang, Chi-Chung Lin, Hua Fan, Jing-Song Zhang, Hai-Ying Bao
A water-soluble polysaccharide, designated FVPA2, was isolated from the fruiting bodies of Flammulina velutipes using DEAE Sepharose Fast Flow and gel-permeation chromatography. Its structure was elucidated by monosaccharide composition and methylation analysis, ultraviolet, Fourier transform infrared spectrometry, and nuclear magnetic resonance spectroscopy. Results showed that FVPA2 was a homogeneous heteropolysaccharide containing galactose, fucose, and mannose in a molar ratio of 5:1:1. High-performance liquid chromatography indicated its molecular weight as 3...
2016: International Journal of Medicinal Mushrooms
https://www.readbyqxmd.com/read/27910758/antimicrobial-coumarins-from-the-oyster-culinary-medicinal-mushroom-pleurotus-ostreatus-agaricomycetes-from-kenya
#15
Lilechi D Baraza, Wekesa Neser, Korir Cheruiyot Jackson, Juma B Fredrick, Ochieno Dennis, Kamau R Wairimu, Aggrey Osogo Keya, Matthias Heydenreich
Pleurotus ostreatus has been widely used as food because of its nutritional and medicinal properties. These have been attributed to the presence of macronutrients, minerals, vitamins, and amino acids, among other secondary metabolites. There are, however, few reports on the antimicrobial activities of different classes of purified compounds from P. ostreatus. This led to the current study, the objective of which was to chemically characterize the antibiotic activities of P. ostreatus against selected human pathogenic bacteria and endophytic fungi...
2016: International Journal of Medicinal Mushrooms
https://www.readbyqxmd.com/read/27910755/comparison-of-the-composition-and-antioxidant-activities-of-phenolics-from-the-fruiting-bodies-of-cultivated-asian-culinary-medicinal-mushrooms
#16
Shaoling Lin, Lai Tsz Ching, Xinxin Ke, Peter Chi Keung Cheung
The composition profile and the antioxidant properties of phenolics in water extracts obtained from the fresh fruiting bodies of 4 common cultivated Asian edible mushrooms-Agrocybe aegerita, Pleurotus ostreatus, P. eryngii, and Pholiota nameko were compared. The water extract from A. aegerita (AaE) had the highest total phenolic content (TPC) at 54.18 ± 0.27 gallic acid equivalents (μmol/L)/mg extract (P < 0.05), as measured by the Folin-Ciocalteu method, and consisted of the largest number (including gallic acid, protocatechuic acid, chlorogenic acid, ferulic acid, and sinapic acid) and total amounts of phenolic acids identified by Fourier transform-ion cyclotron resonance mass spectrometry...
2016: International Journal of Medicinal Mushrooms
https://www.readbyqxmd.com/read/27910754/assessment-of-the-safety-of-the-shiitake-culinary-medicinal-mushroom-lentinus-edodes-agaricomycetes-in-rats-biochemical-hematological-and-antioxidative-parameters
#17
Denise Grotto, Daiane Cristovam Rosa Bueno, Gabriela Karine de Almeida Ramos, Susi Rosa da Costa, Sara Rosicler Vieira Spim, Marli Gerenutti
Lentinus edodes is an edible mushroom studied for use, or as an adjunct, in the prevention of illnesses such as hypertension, hypercholesterolemia, diabetes, and cancer. Despite the functional properties of L. edodes, the doses commonly reported in experimental studies are much higher than those actually consumed. Thus, we aimed to establish the optimum intake levels of L. edodes in vivo. Four groups of male Wistar rats received dry and powdered L. edodes reconstituted in water for 30 days: control (water only), L...
2016: International Journal of Medicinal Mushrooms
https://www.readbyqxmd.com/read/27817090/optimization-of-physical-conditions-for-the-aqueous-extraction-of-antioxidant-compounds-from-ginger-zingiber-officinale-applying-a-box-behnken-design
#18
Juan Ramírez-Godínez, Judith Jaimez-Ordaz, Araceli Castañeda-Ovando, Javier Añorve-Morga, Verónica Salazar-Pereda, Luis Guillermo González-Olivares, Elizabeth Contreras-López
Since ancient times, ginger (Zingiber officinale) has been widely used for culinary and medicinal purposes. This rhizome possesses several chemical constituents; most of them present antioxidant capacity due mainly to the presence of phenolic compounds. Thus, the physical conditions for the optimal extraction of antioxidant components of ginger were investigated by applying a Box-Behnken experimental design. Extracts of ginger were prepared using water as solvent in a conventional solid-liquid extraction. The analyzed variables were time (5, 15 and 25 min), temperature (20, 55 and 90 °C) and sample concentration (2, 6 and 10 %)...
November 5, 2016: Plant Foods for Human Nutrition
https://www.readbyqxmd.com/read/27816657/haematological-biochemical-and-histopathological-aspects-of-hericium-erinaceus-ingestion-in-a-rodent-model-a-sub-chronic-toxicological-assessment
#19
Hariprasath Lakshmanan, Jegadeesh Raman, Pamela David, Kah-Hui Wong, Murali Naidu, Vikineswary Sabaratnam
ETHNOPHARMACOLOGICAL RELEVANCE: Hericium erinaceus is a culinary-medicinal mushroom and has a long history of usage in traditional Chinese medicine as a tonic for stomach disorders, ulcers and gastrointestinal ailments. AIM OF THE STUDY: The present investigation was aimed to evaluate the potential toxic effects of the aqueous extract from the fruiting bodies of H. erinaceus in rats by a sub-chronic oral toxicity study. MATERIALS AND METHODS: In this sub-chronic toxicity study, rats were orally administered with the aqueous extract of H...
December 24, 2016: Journal of Ethnopharmacology
https://www.readbyqxmd.com/read/27774899/spices-therapeutic-potential-in-cardiovascular-health
#20
Subha Rastogi, Madan Mohan Pandey, Aks Rawat
BACKGROUND: Dietary factors play a key role in the development as well as prevention of certain human diseases, including cardiovascular diseases. Currently there has been an increase in global interest to identify medicinal plants that are pharmacologically effective and have low or no side effects for use in preventive medicine. Culinary herbs and spices are an important part of human nutrition in all the cultures of the world. There is a growing amount of literature concerning the potential benefits of these herbs and spices from a health perspective especially in conferring protection against cardiovascular diseases...
October 21, 2016: Current Pharmaceutical Design
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