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https://www.readbyqxmd.com/read/29785774/thymol-thyme-and-other-plant-sources-health-and-potential-uses
#1
REVIEW
Bahare Salehi, Abhay Prakash Mishra, Ila Shukla, Mehdi Sharifi-Rad, María Del Mar Contreras, Antonio Segura-Carretero, Hannane Fathi, Nafiseh Nasri Nasrabadi, Farzad Kobarfard, Javad Sharifi-Rad
Thymol is a naturally occurring phenol monoterpene derivative of cymene and isomer of carvacrol. Thymol (10-64%) is one of the major constituent of essential oils of thyme (Thymus vulgaris L., Lamiaceae), a medicinal plant with several therapeutic properties. This plant, native to Mediterranean regions, is commonly used as a culinary herb and also with a long history of use for different medicinal purposes. Nowadays, thymol and thyme present a wide range of functional possibilities in pharmacy, food, and cosmetic industry...
May 22, 2018: Phytotherapy Research: PTR
https://www.readbyqxmd.com/read/29773008/antimicrobial-cytotoxic-anti-inflammatory-and-antioxidant-activity-of-culinary-processed-shiitake-medicinal-mushroom-lentinus-edodes-agaricomycetes-and-its-major-sulfur-sensory-active-compound-lenthionine
#2
Kristyna Kupcova, Iveta Stefanova, Zuzana Plavcova, Jan Hosek, Pavel Hrouzek, Roman Kubec
The antimicrobial, cytotoxic, anti-inflammatory, and antioxidant properties of aqueous extracts of raw and culinary processed shiitake mushrooms were evaluated and compared with those of lenthionine (1,2,3,5,6-penta-thiepane), the principal aroma-bearing substance of the shiitake medicinal mushroom (Lentinus edodes). Antimicrobial activity was tested using a panel of 4 strains of bacteria, 2 yeasts, and 2 fungi. Cytotoxic properties were evaluated against 3 cell lines (HepG2, HeLa, PaTu), whereas the anti-inflammatory activity of tested samples was assayed based on their ability to attenuate the secretion of the cytokine tumor necrosis factor-α...
2018: International Journal of Medicinal Mushrooms
https://www.readbyqxmd.com/read/29773006/antimelanogenesis-and-anti-inflammatory-activity-of-selected-culinary-medicinal-mushrooms
#3
Hazwani Mat Saad, Kae Shin Sim, Yee Shin Tan
Five culinary-medicinal mushrooms are commonly available in the Malaysian market: Agaricus bisporus (white and brown), Ganoderma lucidum, Hypsizygus marmoreus, Pleurotus floridanus, and P. pulmonarius. These species were selected for use in the current study, the aim of which was to investigate the antimelanogenesis and anti-inflammatory activity of these mushrooms in an attempt to evaluate their potential use in cosmeceuticals. Mushroom fruiting bodies were extracted with hot water, and the extracts were freeze-dried before testing...
2018: International Journal of Medicinal Mushrooms
https://www.readbyqxmd.com/read/29773005/anti-inflammatory-potential-of-in-vitro-cultures-of-the-white-button-mushroom-agaricus-bisporus-agaricomycetes-in-caco-2-cells
#4
Bozena Muszynska, Agata Grzywacz, Katarzyna Kala, Joanna Gdula-Argasinska
Agaricus bisporus (white button mushroom) is one of the most popular culinary-medicinal mushrooms worldwide. This species has for decades been the subject of numerous scientific studies. The aim of this study was to examine the pro- or anti-inflammatory properties of A. bisporus and biomass extracts from in vitro cultures growing in Oddoux medium enriched with α-linolenic acid in colon epithelial Caco-2 cells activated with lipopolysaccharide (LPS) and tumor necrosis factor (TNF)-α. Incubation of Caco-2 cells with A...
2018: International Journal of Medicinal Mushrooms
https://www.readbyqxmd.com/read/29761651/mr%C3%AF-inside-the-meat-pie
#5
John Massie, Michael Kean, Tim Cain
Meat pies have been adopted as one of Australia's favourite foods, and considered an icon by many. The hand-held convenience of the pie has made them a culinary necessity while watching sport, also beloved in Australia. An enduring question about the meat pie is what exactly is inside. This can be difficult to ascertain by digital, ocular or oral exploration. In this study we use MR imaging to study the contents of some of Australia's best loved pies.
May 14, 2018: Journal of Medical Imaging and Radiation Oncology
https://www.readbyqxmd.com/read/29735100/multidirectional-investigations-on-different-parts-of-allium-scorodoprasum-l-subsp-rotundum-l-stearn-phenolic-components-in-vitro-biological-and-in-silico-propensities
#6
Adriano Mollica, Gokhan Zengin, Marcello Locatelli, Carene Marie Nancy Picot-Allain, Mohamad Fawzi Mahomoodally
Allium species have been widely used for culinary and medicinal purposes. This study attempts for the first time to investigate into the enzyme inhibitory potential of different plant parts of Allium scorodoprasum L. subsp. rotundum (L.) Stearn, also known as wild garlic or leek in Turkey. The antioxidant and enzyme inhibitory potential of the flower, stem, and bulb extracts of A. scorodoprasum were assessed using in vitro bio-assays. The phenolic composition of the different plant parts was also established...
June 2018: Food Research International
https://www.readbyqxmd.com/read/29717671/improvement-of-nutritional-and-bioactive-compound-production-by-lion-s-mane-medicinal-mushroom-hericium-erinaceus-agaricomycetes-by-spraying-growth-regulators
#7
Minhthuan Vi, Xueqin Yang, Xianlu Zeng, Rui'an Chen, Liqiong Guo, Junfang Lin, Qianyun He, Qianwang Zheng, Tao Wei
Hericium erinaceus is a popular culinary and medicinal mushroom in China because of its broad beneficial effects. In this study we evaluated the effects of stimulation with 7 growth regulators at 5 different concentrations on improving the production of nutritional and bioactive compounds by H. erinaceus. Results showed that among all the tested regulators, gibberellic acid (GA) increased protein content (165%), free amino acids (100%), polysaccharides (108%), and polyphenols (26%). Spraying nephthyl acetic acid increased polysaccharides and triterpenoids to 4...
2018: International Journal of Medicinal Mushrooms
https://www.readbyqxmd.com/read/29717670/effects-of-cooking-and-in-vitro-digestion-on-antioxidant-properties-and-cytotoxicity-of-the-culinary-medicinal-mushroom-pleurotus-ostreatoroseus-agaricomycetes
#8
Tatiane Brugnari, Pedro Henrique Alves da Silva, Alex Graça Contato, Fabíola Dorneles Inácio, Mariene Marques Nolli, Camila Gabriel Kato, Rosane Marina Peralta, Cristina Giatti Marques de Souza
In this study we evaluated the antioxidant capacity, antimicrobial activity, and cytotoxicity of an aqueous extract of the Pleurotus ostreatoroseus mushroom, which was cooked. Fresh basidiocarps were heated and steamed at 100°C and the resulting aqueous extract was assessed before and after in vitro digestion. Cooking reduced the amounts of phenolic compounds in the extract. The antioxidant activity of the extract was evaluated through the use of 4 methods. The lowest half-maximal effective concentration (EC50) against ABTS radicals was 0...
2018: International Journal of Medicinal Mushrooms
https://www.readbyqxmd.com/read/29717668/its1-5-8s-its2-a-good-marker-for-initial-classification-of-shiitake-culinary-medicinal-lentinus-edodes-agaricomycetes-strains-in-china
#9
Xiao-Xia Song, Yan Zhao, Chun-Yan Song, Chuan-Hua Li, Ying Song, Ming-Jie Chen, Da-Peng Bao, Qi Tan
China is home to rich wild and cultivated strains of Lentinus edodes, an important edible and medicinal mushroom. Artificial selection of L. edodes has a long history, and the widely cultivated strains belong to populations different from those of most wild strains. Internal transcribed spacer (ITS) regions have been used as good markers to identify L. edodes populations. But because ITS regions exhibit incomplete concerted evolution, the use of an ITS to identify L. edodes populations has been questioned. The objective of this study was to determine whether the ITS region is suitable for identifying L...
2018: International Journal of Medicinal Mushrooms
https://www.readbyqxmd.com/read/29604912/purification-and-antithrombotic-potential-of-a-fibrinolytic-enzyme-from-shiitake-culinary-medicinal-mushroom-lentinus-edodes-gna01-agaricomycetes
#10
Jun-Hui Choi, Kyung-Je Kim, Seung Kim
We purified Lentinus edodes GNA01 fibrinolytic enzyme (LEFE) and identified it as a novel metalloprotease. LEFE was purified to homogeneity through a 2-step procedure, with an 8.28-fold increase in specific activity and 5.3% recovery. The molecular mass of LEFE was approximately 38 kDa, based on sodium dodecyl sulfate-polyacrylamide gel electrophoresis. Its optimal pH, optimal temperature, pH stability, and thermal stability were 5, 30°C, 6-7, and 40°C, respectively. LEFE was inhibited by zinc and magnesium ions, and by EDTA and EGTA, indicating that LEFE is a metalloprotease...
2018: International Journal of Medicinal Mushrooms
https://www.readbyqxmd.com/read/29604911/extrinsic-and-intrinsic-apoptotic-responses-induced-by-shiitake-culinary-medicinal-mushroom-lentinus-edodes-agaricomycetes-aqueous-extract-against-a-larynx-carcinoma-cell-line
#11
Tiane C Finimundy, Gustavo Scola, Fernando J Scariot, Aldo J P Dillon, Sidnei Moura, Sérgio Echeverrigaray, João Pegas Henriques, Mariana Roesch-Ely
Cumulative evidence from research studies has shown that the shiitake culinary-medicinal mushroom, Lentinus edodes, is an excellent source of natural antitumor agents and is capable of inhibiting cancer cell growth. However, the cell signaling pathway that leads tumor cells to apoptosis is not well understood because many chemical compounds may be acting. This study investigated the chemopreventive effects of an L. edodes aqueous extract on human HEp-2 epithelial larynx carcinoma cells and normal human MRC-5 lung fibroblasts by identifying proliferative and apoptotic pathways...
2018: International Journal of Medicinal Mushrooms
https://www.readbyqxmd.com/read/29584636/response-of-plant-secondary-metabolites-to-environmental-factors
#12
REVIEW
Li Yang, Kui-Shan Wen, Xiao Ruan, Ying-Xian Zhao, Feng Wei, Qiang Wang
Plant secondary metabolites (SMs) are not only a useful array of natural products but also an important part of plant defense system against pathogenic attacks and environmental stresses. With remarkable biological activities, plant SMs are increasingly used as medicine ingredients and food additives for therapeutic, aromatic and culinary purposes. Various genetic, ontogenic, morphogenetic and environmental factors can influence the biosynthesis and accumulation of SMs. According to the literature reports, for example, SMs accumulation is strongly dependent on a variety of environmental factors such as light, temperature, soil water, soil fertility and salinity, and for most plants, a change in an individual factor may alter the content of SMs even if other factors remain constant...
March 27, 2018: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
https://www.readbyqxmd.com/read/29530611/anethum-graveolens-dill-a-medicinal-herb-induces-apoptosis-and-cell-cycle-arrest-in-hepg2-cell-line
#13
Furkhan Ahmed Mohammed, Ayman I Elkady, Fareeduddin Quadri Syed, Muqtadir Baig Mirza, Khalid Rehman Hakeem, Saleh Alkarim
ETHNOPHARMACOLOGICAL RELEVANCE: The medicinal herb, Anethum graveolens L. (dill) is one of the potent culinary herbs used as an alternative form of medicine worldwide. The unguent topical Oil from the aerial parts of A. graveolens was found to be effective in the management of uterus cancer in ethnomedicine has been reported. BACKGROUND: The incidence and mortality rates of Hepatocellular carcinoma (HCC) are steadily rising worldwide, especially, in underdeveloped and developing countries...
March 9, 2018: Journal of Ethnopharmacology
https://www.readbyqxmd.com/read/29499374/borago-officinalis-l-attenuates-uvb-induced-skin-photodamage-via-regulation-of-ap-1-and-nrf2-are-pathway-in-normal-human-dermal-fibroblasts-and-promotion-of-collagen-synthesis-in-hairless-mice
#14
Seul A Seo, Bom Park, Eunson Hwang, Sang-Yong Park, Tae-Hoo Yi
Ultraviolet B (UVB) irradiation is regarded as the main cause of skin photodamage. After exposure to UVB irradiation, collagen degradation is accelerated by upregulation of matrix metalloproteinases (MMPs), and collagen synthesis is decreased via downregulation of transforming growth factor (TGF)-β1 signaling. Borago officinalis L. (BO) is an annual herb with medicinal and culinary applications. Although BO has been demonstrated to have antioxidant and anti-inflammatory activities, its potential anti-photoaging effects have not been examined...
July 1, 2018: Experimental Gerontology
https://www.readbyqxmd.com/read/29487458/lc-esi-q-tof-ms-ms-profiling-and-antioxidant-activity-of-phenolics-from-l-sativum-seedcake
#15
Deepak Kadam, Shanooba Palamthodi, S S Lele
Lepidium sativum is widely used as a culinary and medicinal herb and is claimed to cure many diseases. In this study, an attempt was made to investigate the biochemical composition and functional properties of L. sativum ethanolic extract. The extract contained a total phenolic content of 11.03 ± 0.75 (mg GAE/g dw plant material) and a flavonoid content of 4.79 ± 0.24 (mg QE/100 g dw plant material). Further, the extract was characterized by LC-ESI-Q-TOF-MS/MS profiling and the results showed that the ethanolic fraction contains many important phenolics such as Kaempferol, Coumaroylquinic acid, p -Coumaroyl glycolic acid, Caffeic acid...
March 2018: Journal of Food Science and Technology
https://www.readbyqxmd.com/read/29477139/effects-of-thymol-a-natural-phenolic-compound-on-human-gastric-adenocarcinoma-cells-in-vitro
#16
Ayse Günes-Bayir, Abdurrahim Kocyigit, Eray Metin Güler, Huriye Senay Kiziltan
Context • Alternative and complementary medicine has gained importance in anticancer treatment, reflecting a movement toward an integrated approach to treating various diseases. Natural products originating from plants can contain biologically active substances. Thymol is a major component of many plants from the family Lamiaceae that are often used for medicinal and culinary purposes in Mediterranean countries. Objective • The purpose of the present study was to investigate thymol's cytotoxic, genotoxic, apoptotic effects on gastric adenocarcinoma (AGS) cells, including measurement of reactive oxygen species (ROS) and glutathione (GSH) levels at the same time...
February 24, 2018: Alternative Therapies in Health and Medicine
https://www.readbyqxmd.com/read/29448760/identification-of-new-compounds-from-sage-flowers-salvia-officinalis-l-as-markers-for-quality-control-and-the-influence-of-the-manufacturing-technology-on-the-chemical-composition-and-antibacterial-activity-of-sage-flower-extracts
#17
Sebastian Gericke, Tilo Lübken, Diana Wolf, Martin Kaiser, Christian Hannig, Karl Speer
Parts of Salvia species such as its flowers and leaves are currently used as a culinary herb and for some medicinal applications. To distinguish the different sage extracts it is necessary to analyze their individual chemical compositions. Their characteristic compounds might be established as markers to differentiate between sage flowers and leaf extracts or to determine the manufacturing technology and storage conditions. Tri-p-coumaroylspermidine can be detected only in flowers and has been described here for Salvia and Lavandula species for the first time...
February 28, 2018: Journal of Agricultural and Food Chemistry
https://www.readbyqxmd.com/read/29433220/coriander-coriandrum-sativum-a-promising-functional-food-toward-the-well-being
#18
REVIEW
Veda Prachayasittikul, Supaluk Prachayasittikul, Somsak Ruchirawat, Virapong Prachayasittikul
Coriandrum sativum (C. sativum) or coriander is one of the most popularly used spices in culinary worldwide, and its medicinal values has been recognized since ancient time. C. sativum contains bioactive phytochemicals that are accounted for a wide range of biological activities including antioxidant, anticancer, neuroprotective, anxiolytic, anticonvulsant, analgesic, migraine-relieving, hypolipidemic, hypoglycemic, hypotensive, antimicrobial, and antiinflammatory activities. The major compound, linalool, abundantly found in seeds is remarked for its abilities to modulate many key pathogenesis pathways of diseases...
March 2018: Food Research International
https://www.readbyqxmd.com/read/29408310/phytochemical-characterization-and-biological-activity-evaluation-of-ethanolic-extract-of-cinnamomum-zeylanicum
#19
Ishrat Husain, Rumana Ahmad, Anu Chandra, Syed Tasleem Raza, Yogeshwer Shukla, Farzana Mahdi
ETHNOPHARMACOLOGICAL RELEVANCE: India being a multicultural nation, every region of the country offers a distinct culinary flavor and taste. These flavors are attributed to spices and condiments which form the mainstay of Indian cuisine. Most of these spices and condiments are derived from various biodiversity hotspots in India and form the crux of India's multidiverse and multicultural cuisine. Apart from their varying aromas, flavors and tastes, these spices and condiments are known to possess several medicinal properties also...
March 22, 2018: Journal of Ethnopharmacology
https://www.readbyqxmd.com/read/29405040/phytochemical-composition-biological-potential-and-enzyme-inhibition-activity-of-scandix-pecten-veneris-l
#20
Abdul Wahab, Syed Aleem Jan, Abdur Rauf, Zia Ur Rehman, Zahid Khan, Aftab Ahmed, Fatima Syed, Sher Zaman Safi, Hamayun Khan, Muhammad Imran
OBJECTIVE: Scandix pecten-veneris L. is a less studied wild edible herb and is considered an extinct plant species in many parts of the world. This study was designed to evaluate its phytochemical composition and biological potential of S. pecten-veneris L. METHODS: Phytochemicals including alkaloids, flavonoids, polyphenols, and tannins were determined in extracts of S. pecten-veneris. Antioxidant activity was determined using 2,2-diphenyl-1-picrylhydrazyl (DPPH), while reducing power was tested by ferric reducing/antioxidant power (FRAP) assay...
2018: Journal of Zhejiang University. Science. B
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