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https://www.readbyqxmd.com/read/28108495/neural-representations-of-belief-concepts-a-representational-similarity-approach-to-social-semantics
#1
Anna Leshinskaya, Juan Manuel Contreras, Alfonso Caramazza, Jason P Mitchell
The present experiment identified neural regions that represent a class of concepts that are independent of perceptual or sensory attributes. During functional magnetic resonance imaging scanning, participants viewed names of social groups (e.g. Atheists, Evangelicals, and Economists) and performed a one-back similarity judgment according to 1 of 2 dimensions of belief attributes: political orientation (Liberal to Conservative) or spiritualism (Spiritualist to Materialist). By generalizing across a wide variety of social groups that possess these beliefs, these attribute concepts did not coincide with any specific sensory quality, allowing us to target conceptual, rather than perceptual, representations...
January 19, 2017: Cerebral Cortex
https://www.readbyqxmd.com/read/28107237/evaluating-a-posterior-approach-for-surgical-treatment-of-thoracolumbar-pseudarthrosis-in-ankylosing-spondylitis
#2
Ting Wang, Dechun Wang, Yanan Cong, Chuqiang Yin, Shuzhong Li, Xiaoliang Chen
STUDY DESIGN: Retrospective study of a posterior approach for surgical treatment of thoracolumbar pseudarthrosis in ankylosing spondylitis (AS). OBJECTIVE: The aim of the current study was to report the surgical results of symptomatic thoracolumbar pseudarthrosis in AS through a posterior approach. SUMMARY OF BACKGROUND DATA: Spinal pseudarthrosis is a well-known complication in AS. The condition may complicate with mechanical back pain, spinal deformity, and sometimes neurological deficits...
February 2017: Clinical Spine Surgery
https://www.readbyqxmd.com/read/28107204/non-invasive-blood-glucose-detection-system-based-on-conservation-of-energy-method
#3
Yang Zhang, Jian-Ming Zhu, Yong-Bo Liang, Hong-Bo Chen, Shi-Min Yin, Zhen-Cheng Chen
The most common method used for minimizing the occurrence of diabetes complications is frequent glucose testing to adjust the insulin dose. However, using blood glucose (BG) meters presents a risk of infection. It is of great importance to develop non-invasive BG detection techniques. To realize high-accuracy, low-cost and continuous glucose monitoring, we have developed a non-invasive BG detection system using a mixed signal processor 430 (MSP430) microcontroller. This method is based on the combination of the conservation-of-energy method with a sensor integration module, which collects physiological parameters, such as the blood oxygen saturation (SPO2), blood flow velocity and heart rate...
January 20, 2017: Physiological Measurement
https://www.readbyqxmd.com/read/28100860/-a-pediatric-case-of-intractable-cerebrospinal-fluid-leakage-after-implantation-of-an-intrathecal-baclofen-pump
#4
Akitsugu Morishita, Hideo Aihara, Tomoaki Nakai, Masao Adachi
Intrathecal baclofen(ITB)infusion can offer a useful treatment for severe spasticity;however, numerous complications have been reported. We report a pediatric case in which intractable cerebrospinal fluid(CSF)leakage associated with several inconvenient symptoms arose after implantation of the ITB pump system. A 10-year-old girl with spastic quadriparesis and athetoid cerebral palsy underwent implantation of an ITB delivery system. After discharge, she presented with fluid collection surrounding the pump in the abdomen...
January 2017: No Shinkei Geka. Neurological Surgery
https://www.readbyqxmd.com/read/28096264/adherens-junctions-on-the-move-membrane-trafficking-of-e-cadherin
#5
Lena Brüser, Sven Bogdan
Cadherin-based adherens junctions are conserved structures that mediate epithelial cell-cell adhesion in invertebrates and vertebrates. Despite their pivotal function in epithelial integrity, adherens junctions show a remarkable plasticity that is a prerequisite for tissue architecture and morphogenesis. Epithelial cadherin (E-cadherin) is continuously turned over and undergoes cycles of endocytosis, sorting and recycling back to the plasma membrane. Mammalian cell culture and genetically tractable model systems such as Drosophila have revealed conserved, but also distinct, mechanisms in the regulation of E-cadherin membrane trafficking...
January 17, 2017: Cold Spring Harbor Perspectives in Biology
https://www.readbyqxmd.com/read/28072794/does-percutaneous-vertebroplasty-or-balloon-kyphoplasty-for-osteoporotic-vertebral-compression-fractures-increase-the-incidence-of-new-vertebral-fractures-a-meta-analysis
#6
Hui Zhang, Caiyuan Xu, Tongxing Zhang, Zhongyu Gao, Tao Zhang
BACKGROUND: Because of an aging population,osteoporotic vertebral fractures are becoming more frequent.Conservative therapy was considered the gold standard for treating osteoporotic vertebral compression fractures (OVCFs) in the past. Percutaneous vertebroplasty (PVP) or balloon kyphoplasty (BKP) as minimally invasive techniques are new treatments that are widely used for painful OVCFs. However, an increase in new vertebral compression fractures at non-treated levels following augmentation is of concern...
January 2017: Pain Physician
https://www.readbyqxmd.com/read/28068753/retrospective-matched-pair-cohort-study-on-effect-of-bisegmental-fenestration-versus-hemilaminectomy-for-bisegmental-spinal-canal-stenosis-at-l3-l4-and-l4-l5
#7
Julia Schüppel, Friedrich Weber
Background The main symptoms of degenerative lumbar spinal canal stenosis are progressive back pain, spinal claudication, and, occasionally, sensory and motor deficits. Impairments particularly occur during walking, standing, and sitting. Thus social and vocational activities are increasingly restricted, causing considerable suffering for patients. Surgical therapies are superior to conservative ones. This article studies the outcome of 2-level fenestration versus hemilaminectomy for bisegmental spinal stenosis decompression...
January 9, 2017: Journal of Neurological Surgery. Part A, Central European Neurosurgery
https://www.readbyqxmd.com/read/28056090/accurate-de-novo-prediction-of-protein-contact-map-by-ultra-deep-learning-model
#8
Sheng Wang, Siqi Sun, Zhen Li, Renyu Zhang, Jinbo Xu
MOTIVATION: Protein contacts contain key information for the understanding of protein structure and function and thus, contact prediction from sequence is an important problem. Recently exciting progress has been made on this problem, but the predicted contacts for proteins without many sequence homologs is still of low quality and not very useful for de novo structure prediction. METHOD: This paper presents a new deep learning method that predicts contacts by integrating both evolutionary coupling (EC) and sequence conservation information through an ultra-deep neural network formed by two deep residual neural networks...
January 2017: PLoS Computational Biology
https://www.readbyqxmd.com/read/28055111/there-and-back-again-loss-and-reacquisition-of-two-cys-photocycles-in-cyanobacteriochromes
#9
Nathan C Rockwell, Shelley S Martin, J Clark Lagarias
Cyanobacteriochromes (CBCRs) are cyanobacterial photoreceptors distantly related to phytochromes. Both families use linear tetrapyrrole (bilin) chromophores that are covalently attached to a conserved Cys residue. CBCRs are more spectrally diverse than phytochromes, with known examples detecting light from the near ultraviolet to the edge of the infrared (370-750 nm). Detection of ultraviolet to blue light by CBCRs is mediated by a second Cys residue, which forms a covalent linkage to the bilin C10 atom. Second linkage formation is best understood in a subfamily possessing a conserved Asp-Xaa-Cys-Phe (DXCF) motif...
January 5, 2017: Photochemistry and Photobiology
https://www.readbyqxmd.com/read/28050425/severe-left-ventricular-endomyocardial-fibrosis-presenting-as-biventricular-failure-in-a-young-adult-a-case-report
#10
Harpreet Singh Sandhu, Sampathkumar Mahadevappa Mahendrakar, Rajebali Ramzanali Pethani, Azizullah Hafizullah Khan, Yunus Shafi Loya
Endomyocardial Fibrosis (EMF) is a form of progressive restrictive cardiomyopathy of unclear aetiology prevalent in areas within 15(0) of equator including coastal areas of Kerala a few decades back. It inflicts young adults and carries a poor prognosis due to limited options for treatment. Fortunately, the incidence of cases is now declining due to improvement in health and hygiene standards. Here, we review the aetiology and pathogenesis of EMF and report a case of a young male from Mumbai (non-endemic area) presenting with progressively worsening breathlessness and signs of heart failure unresponsive to conventional medical treatment...
November 2016: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28043001/flow-cytometry-for-immediate-follow-up-of-drinking-water-networks-after-maintenance
#11
Sam Van Nevel, Benjamin Buysschaert, Karen De Roy, Bart De Gusseme, Lieven Clement, Nico Boon
Drinking water networks need maintenance every once in a while, either planned interventions or emergency repairs. When this involves opening of the water pipes, precautionary measures need to be taken to avoid contamination of the drinking water at all time. Drinking water suppliers routinely apply plating for faecal indicator organisms as quality control in such a situation. However, this takes at least 21 h of waiting time, which can be crucial when dealing with major supply pipes. A combination of flow cytometric (FCM) bacterial cell counts with FCM fingerprinting techniques is proposed in this study as a fast and sensitive additional technique...
December 25, 2016: Water Research
https://www.readbyqxmd.com/read/28042448/statistical-analysis-of-the-frequency-distribution-of-signs-and-symptoms-of-patients-with-temporomandibular-disorders
#12
R Franco, M Basili, A Venditti, C Chiaramonte, L Ottria, A Barlattani, P Bollero
The purpose of this text is to evaluate the distribution by sex and age of TMD patients and the frequency of pain on palpation of the lateral pterygoid muscle, pterygoid internal, sternocleidomastoid, masseter, temporal. The purpose is also to assess the existence of direct correlations between the articulating click and lateral deviation, the headache and tenderness of the temporal, the back pain and tenderness of the sternocleidomastoid, the postural disorders and difficulty finding the exact mating closing, the disorders related to previous dental procedures (large conservative reconstructions, rehabilitations fixed dentures and dental extractions) and tenderness to the temporal and masseter...
October 2016: Oral & Implantology
https://www.readbyqxmd.com/read/28035232/back-into-the-wild-apply-untapped-genetic-diversity-of-wild-relatives-for-crop-improvement
#13
REVIEW
Hengyou Zhang, Neha Mittal, Larry J Leamy, Oz Barazani, Bao-Hua Song
Deleterious effects of climate change and human activities, as well as diverse environmental stresses, present critical challenges to food production and the maintenance of natural diversity. These challenges may be met by the development of novel crop varieties with increased biotic or abiotic resistance that enables them to thrive in marginal lands. However, considering the diverse interactions between crops and environmental factors, it is surprising that evolutionary principles have been underexploited in addressing these food and environmental challenges...
January 2017: Evolutionary Applications
https://www.readbyqxmd.com/read/28028448/a-novel-technique-to-repair-a-transverse-sacral-fracture-in-a-previously-fused-lumbosacral-spondylolisthesis
#14
Thomas Noh, Mokbel K Chedid
BACKGROUND: Transverse fractures of the sacrum are rare, and surgical treatment for these fractures ranges from conservative to challenging. Transverse stress fractures of the sacrum after placement of lumbar-to-sacral instrumentation have been previously described. We report a new technique to repair a transverse Type-2 Roy-Camille fracture with spondylolisthesis of S1 over S2 in a previously fused instrumented high-grade L4-L5, L5-S1 spondylolisthesis. CASE DESCRIPTION: A 64-year-old female who previously had an L4-L5, L5-S1 fusion for spondylolisthesis presented with excruciating lower back pain and radiculopathy for over 6 months...
2016: Surgical Neurology International
https://www.readbyqxmd.com/read/28025275/mirnas-in-ancient-tissue-specimens-of-the-tyrolean-iceman
#15
Andreas Keller, Stephanie Kreis, Petra Leidinger, Frank Maixner, Nicole Ludwig, Christina Backes, Valentina Galata, Gea Guerriero, Tobias Fehlmann, Andre Franke, Benjamin Meder, Albert Zink, Eckart Meese
The analysis of nucleic acids in ancient samples is largely limited to DNA. Small non-coding RNAs (microRNAs) are known to be evolutionary conserved and stable. To gain knowledge on miRNAs measured from ancient samples we profiled microRNAs in cryoconserved mummies. First, we established the approach on a World War One warrior, the "Kaiserjäger", which has been preserved for almost one century. Then, we profiled seven ancient tissue specimens including skeletal muscle, stomach mucosa, stomach content and two corpus organ tissues of the 5,300 year-old copper age mummy Iceman and compared these profiles to the presence of organ-specific miRNAs in modern tissues...
December 26, 2016: Molecular Biology and Evolution
https://www.readbyqxmd.com/read/28018090/natural-tibialization-of-fibula-in-non-union-tibia-two-cases
#16
Vinay Prabhat, Gauresh S Vargaonkar, Sunil R Mallojwar, Ramesh Kumar
BACKGROUND: Non-union of tibia is known to be a common complication after fracture both bones of leg treated conservatively. During the course of natural healing, fibula usually unites early as it had more soft tissue attachment and vascular supply. Due to early union of fibula and absence of axial force across the tibia, it undergoes non-union. CASE CHARACTERISTICS: Two cases, a 32-year-old male and 65-year-old female treated conservatively for fracture both bones of leg long years back, presented to us with mild calf pain on and off...
October 2016: Journal of Clinical Orthopaedics and Trauma
https://www.readbyqxmd.com/read/28017582/outcomes-of-conservative-management-of-spontaneous-celiac-artery-dissection
#17
Akihiro Hosaka, Masaru Nemoto, Tetsuro Miyata
OBJECTIVE: Spontaneous celiac artery (CA) dissection without associated aortic dissection is a rare condition. Although this condition has been diagnosed more frequently with the advent of improved diagnostic imaging modalities, its pathogenesis and treatment strategy remain to be established. The present study examined the clinical features and outcomes of conservative management of this disease. METHODS: The study included 12 patients (10 men and two women) in whom spontaneous CA dissection was diagnosed between 2007 and 2015...
December 22, 2016: Journal of Vascular Surgery
https://www.readbyqxmd.com/read/28012752/percutaneous-stone-manipulation
#18
P Alken, G Hutschenreiter, R Günther, M Marberger
Percutaneous stone manipulation by direct ultrasound disintegration, extraction or chemolysis was done on 34 patients. A total of 15 patients presented with an operatively established nephrostomy, while percutaneous nephrostomy and subsequent dilation of the nephrostomy channel were done in 19. The rate of complete stone clearance was 19 of 20 stones after percutaneous nephrostomy and 8 of 16 stones in the group with an operatively established nephrostomy. The primary goal, to remove obstructing pelvic stones, was achieved in all cases...
December 21, 2016: Journal of Urology
https://www.readbyqxmd.com/read/28003290/surgical-versus-conservative-treatment-for-lumbar-disc-herniation-a-prospective-cohort-study
#19
Marinella Gugliotta, Bruno R da Costa, Essam Dabis, Robert Theiler, Peter Jüni, Stephan Reichenbach, Hans Landolt, Paul Hasler
OBJECTIVES: Evidence comparing the effectiveness of surgical and conservative treatment of symptomatic lumbar disc herniation is controversial. We sought to compare short-term and long-term effectiveness of surgical and conservative treatment in sciatica symptom severity and quality of life in patients with lumbar disc herniation in a routine clinical setting. METHODS: A prospective cohort study of a routine clinical practice registry consisting of 370 patients...
December 21, 2016: BMJ Open
https://www.readbyqxmd.com/read/28002916/mesenchymal-stem-cells-for-intervertebral-disc-regeneration
#20
G Vadalà, F Russo, L Ambrosio, R Papalia, V Denaro
Low back pain (LBP) is one of the most common disabling symptoms affecting the adult population throughout the industrialized world. The main cause underlying this condition is intervertebral disc degeneration (IDD), which is characterized by progressive decrease of the proteoglycan content within the nucleus pulposus (NP), leading to disc dehydration and loss of its morpho-functional and biomechanical properties. To date, LBP treatment is based upon conservative and invasive procedures which are not capable of restoring the degenerative alterations of the disc, as they only help relieve the symptoms and/or slow down disc degeneration and are, nonetheless, characterized by significant comorbidities, costs and secondary risks...
October 2016: Journal of Biological Regulators and Homeostatic Agents
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