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Arterial stiffness

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https://www.readbyqxmd.com/read/29166584/swell-or-not-too-swell-cytokines-regulate-arterial-aneurysm-formation
#1
Peter Libby, Amélie Vrooman
Arterial remodeling participates pivotally in many diseases including arterial aneurysms. In this issue of Immunity, Da Ros et al. (2017) report that, in experimental aortic aneurysm formation, neutralization of interleukin-1β reduced arterial wall stiffness and hampered aneurysm development.
November 21, 2017: Immunity
https://www.readbyqxmd.com/read/29164683/is-hypertension-the-fate-of-aortic-coarctation-patients-treated-with-cheatham-platinum-cp-stent
#2
Ali Baykan, Ayse G Demiraldi, Onur Tasci, Ozge Pamukcu, Suleyman Sunkak, Kazım Uzum, Sadettin Sezer, Nazmi Narin
AIM: The aim of this study is to address the presence of hypertension and risk for cardiovascular diseases in patients with Coarctation of the Aorta (CoA) who were treated with endovascular stent placement. METHODS: Twenty patients (mean age: 14.2 ± 3.9 years) who were treated with stent and 20 age- and sex-matched controls were included to the study. Structure and functions of left ventricle were assessed by echocardiography. Carotid intima media (CIM) thickness was measured by using sonography as a marker for detecting cardiovascular risk...
November 21, 2017: Journal of Interventional Cardiology
https://www.readbyqxmd.com/read/29163200/a-pulse-wave-velocity-based-method-to-assess-the-mean-arterial-blood-pressure-limits-of-autoregulation-in-peripheral-arteries
#3
Ananya Tripathi, Yurie Obata, Pavel Ruzankin, Narwan Askaryar, Dan E Berkowitz, Jochen Steppan, Viachaslau Barodka
Background: Constant blood flow despite changes in blood pressure, a phenomenon called autoregulation, has been demonstrated for various organ systems. We hypothesized that by changing hydrostatic pressures in peripheral arteries, we can establish these limits of autoregulation in peripheral arteries based on local pulse wave velocity (PWV). Methods: Electrocardiogram and plethysmograph waveforms were recorded at the left and right index fingers in 18 healthy volunteers. Each subject changed their left arm position, keeping the right arm stationary...
2017: Frontiers in Physiology
https://www.readbyqxmd.com/read/29159794/high-fat-high-sugar-diet-induced-subendothelial-matrix-stiffening-is-mitigated-by-exercise
#4
Julie C Kohn, Julian Azar, Francesca Seta, Cynthia A Reinhart-King
Consumption of a high-fat, high-sugar diet and sedentary lifestyle are correlated with bulk arterial stiffening. While measurements of bulk arterial stiffening are used to assess cardiovascular health clinically, they cannot account for changes to the tissue occurring on the cellular scale. The compliance of the subendothelial matrix in the intima mediates vascular permeability, an initiating step in atherosclerosis. High-fat, high-sugar diet consumption and a sedentary lifestyle both cause micro-scale subendothelial matrix stiffening, but the impact of these factors in concert remains unknown...
November 20, 2017: Cardiovascular Engineering and Technology
https://www.readbyqxmd.com/read/29158357/evidence-for-a-role-of-vascular-endothelium-in-the-control-of-arterial-wall-viscosity-in-humans
#5
Frederic Roca, Michele Iacob, Isabelle Remy-Jouet, Jeremy Bellien, Robinson Joannides
Arterial wall viscosity (AWV) is a major cause of energy dissipation along the arterial tree. Its determinants remain controversial but an active endothelial regulation has been suggested. Our objective was to assess in humans the physiological role of endothelium-derived nitric oxide (NO), epoxyeicosatrienoic acids and the effect of modulating smooth muscle tone in the regulation of AWV. We simultaneously measured radial artery diameter, wall thickness, and arterial pressure in healthy volunteers during the local infusion of inhibitors of NO-synthase (N(G)-monomethyl-l-arginine), epoxyeicosatrienoic acids synthesis by cytochrome P450 (fluconazole), the epoxyeicosatrienoic acids cellular targets calcium-activated potassium channels (tetraethylammonium), alone and in combination...
November 20, 2017: Hypertension
https://www.readbyqxmd.com/read/29155890/longitudinal-fasting-blood-glucose-patterns-and-arterial-stiffness-risk-in-a-population-without-diabetes
#6
Yuntao Wu, Junxing Yu, Cheng Jin, Yun Li, Jinmei Su, Guoqing Wei, Xiaoming Zheng, Jingsheng Gao, Wenyuan Gao, Shouling Wu
OBJECTIVE: To identify long-term fasting blood glucose trajectories and to assess the association between the trajectories and the risk of arterial stiffness in individuals without diabetes. METHODS: We enrolled 16,454 non-diabetic participants from Kailuan cohort. Fasting blood glucose concentrations were measured in 2006, 2008, and 2010 survey. Brachial-ankle pulse wave velocities were measured during 2011 to 2016. Multivariate regression model was used to estimate the difference of brachial-ankle pulse wave velocity levels and logistic regression was used to calculate odds ratios (ORs) and 95% confidence intervals (95%CIs) of arterial stiffness risk, according to the fasting blood glucose trajectories...
2017: PloS One
https://www.readbyqxmd.com/read/29154683/arterial-stiffness-in-childhood-a-predictor-for-later-cardiovascular-disease
#7
Fariba Ahmadizar, Trudy Voortman
No abstract text is available yet for this article.
January 1, 2017: European Journal of Preventive Cardiology
https://www.readbyqxmd.com/read/29153673/pregnancy-complications-and-later-vascular-ultrasound-measures-a-cohort-study
#8
Emily W Harville, Markus Juonala, Jorma S A Viikari, Mika Kähönen, Olli T Raitakari
OBJECTIVES: Pregnancy complications predict or even predispose to later cardiovascular disease in the mother. We examined whether pregnancy complications are associated with post-pregnancy measures of endothelial dysfunction and arterial stiffness. STUDY DESIGN: Prospective cohort; Data for 847 women female participants in the Cardiovascular Risk in Young Finns study were linked with the national birth registry. Preterm birth (<37weeks), low birthweight (<2500g), small-for-gestational-age (weight <10th percentile for gestational age), and hypertensive disorders of pregnancy were examined as predictors of later vascular measures...
October 2017: Pregnancy Hypertension
https://www.readbyqxmd.com/read/29153362/in-vivo-assessment-of-placental-elasticity-in-intrauterine-growth-restriction-by-shear-wave-elastography
#9
Hatice Arioz Habibi, Ebru Alici Davutoglu, Sedat Giray Kandemirli, Mine Aslan, Aysegul Ozel, Ayse Kalyoncu Ucar, Pinar Zeytun, Riza Madazli, Ibrahim Adaletli
PURPOSE: In this study, we evaluated the placental elasticity in vivo by shear-wave elastography in pregnant women under follow-up for intrauterine growth restriction (IUGR) and compared the elasticity values to normal pregnancies. MATERIAL AND METHODS: This prospective study included 42 pregnant women with a possible diagnosis of intrauterine growth restriction based on obstetrical grayscale and Doppler ultrasonography and 42 women with a normal pregnancy during the 2nd and 3rd trimester...
December 2017: European Journal of Radiology
https://www.readbyqxmd.com/read/29151492/determinants-of-the-change-in-arterial-stiffness-in-peritoneal-dialysis-patients
#10
Mitsutaka Nakahigashi, Hiroyasu Tsukaguchi, Satoshi Morimoto, Chikara Nakano, Hiroko Ueda, Kazunori Someya, Makiko Kusabe, Sanae Kikuchi, Takanobu Imada, Ichiro Shiojima
Arterial stiffness is an important risk factor for cardiovascular disease (CVD) in patients with end-stage renal failure. However, little is known about the factors that contribute to arterial rigidity in peritoneal dialysis (PD) patients. The aim of this study was to define the pattern and determinants of the longitudinal change in arterial stiffness after PD initiation.Arterial stiffening was estimated for 46 PD patients by using brachial-ankle pulse wave velocity (baPWV) and carotid intima-media thickness (cIMT)...
November 17, 2017: International Heart Journal
https://www.readbyqxmd.com/read/29148291/effectiveness-and-safety-of-anti-ischemic-trimetazidine-in-patients-with-stable-angina-pectoris-and-type-2-diabetes
#11
Zsófia Meiszterics, Attila Kónyi, Gábor Hild, Zsolt Sárszegi, Balázs Gaszner
Aim & methods: This 6-month prospective, observational, noninterventional, open-label clinical study assessed the effectiveness/safety of trimetazidine in 737 patients with stable angina pectoris and Type 2 diabetes mellitus (OGYI/51534-1/2014). RESULTS: Trimetazidine-based therapy was effective in stable coronary artery disease, with significant improvements from baseline (p < 0.05) in: number of angina attacks/week (2.9 ± 2.4 vs 1.1 ± 1.6), angina severity (Canadian Cardiovascular Society Classification 1...
November 17, 2017: Journal of Comparative Effectiveness Research
https://www.readbyqxmd.com/read/29147168/study-of-the-characteristics-of-pulmonary-trunk-in-pulmonary-hypertension-secondary-to-left-heart-disease-using-pressure-velocity-loops-pu-loops
#12
Shizuo Hanya, Kengo Yoshii, Motoaki Sugawara
Objectives: Although pulmonary hypertension (PH) caused by left heart disease (PH-LHD) is more common in PH, little is known about its properties of pulmonary artery (PA) in PH-LHD. The purpose of this study was to measure pulmonary regional pulse wave velocity (PWV) and to quantify the magnitude of reflected waves in patients with PH-LHD by the analysis of the pressure-velocity loops (PU-loop). Methods: High-fidelity PA pressure (Pm) and PA velocity (Vm) were measured in 11 subjects with PH-LHD (mean Pm>25 mmHg), 1 subject with atrial septal defect (ASD) without PH and 12 control subjects, using multisensor catheters...
September 25, 2017: Annals of Vascular Diseases
https://www.readbyqxmd.com/read/29147132/numerical-investigation-of-pulse-wave-propagation-in-arteries-using-fluid-structure-interaction-capabilities
#13
Hisham Elkenani, Essam Al-Bahkali, Mhamed Souli
The aim of this study is to present a reliable computational scheme to serve in pulse wave velocity (PWV) assessment in large arteries. Clinicians considered it as an indication of human blood vessels' stiffness. The simulation of PWV was conducted using a 3D elastic tube representing an artery. The constitutive material model specific for vascular applications was applied to the tube material. The fluid was defined with an equation of state representing the blood material. The onset of a velocity pulse was applied at the tube inlet to produce wave propagation...
2017: Computational and Mathematical Methods in Medicine
https://www.readbyqxmd.com/read/29145340/open-repair-of-intraoperative-popliteal-artery-injury-during-total-knee-arthroplasty-in-a-patient-with-severe-hemophilia-a-a-case-report-and-literature-review
#14
Bin Feng, Ke Xiao, Jiang Shao, Yu Fan, Xisheng Weng
RATIONALE: Arterial injuries during total knee arthroplasty (TKA) though rare may occur. Hemophilia may further challenge the management of such injury. PATIENT CONCERNS: A 48-year-old male patient with severe hemophilia type A and stiff knee arthropathy underwent bilateral TKAs. Left popliteal artery injury was detected at the end of the left TKA. DIAGNOSES: Urgent angiography confirmed the diagnosis of the left popliteal artery transection...
November 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29145217/association-of-female-sex-and-heart-rate-with-increased-arterial-stiffness-in-patients-with-type-2-diabetes-mellitus
#15
Min Kyung Kang, Jae Myung Yu, Kwang Jin Chun, Jaehuk Choi, Seonghoon Choi, Namho Lee, Jung Rae Cho
OBJECTIVE: This study aimed to evaluate the factors associated with increased arterial stiffness (IAS) measured by pulse wave velocity (PWV) and its clinical implications in patients with type 2 diabetes mellitus (DM). METHODS: This was an observational, cross-sectional study. The ankle-brachial PWV was used to measure arterial stiffness, and 310 patients (mean age, 49±9 years; 180 men) with type 2 DM were divided into two groups according to the results of PWV: Group 1 (IAS; n=214) and Group 2 (normal arterial stiffness; n=96)...
November 2017: Anatolian Journal of Cardiology
https://www.readbyqxmd.com/read/29143384/enhanced-ventricular-arterial-coupling-during-a-2-year-physical-activity-program-in-patients-with-rheumatoid-arthritis
#16
Philip Sarajlic, Cecilia Fridén, Lars H Lund, Aristomenis Manouras, Ashwin Venkateshvaran, Susanna C Larsson, Birgitta Nordgren, Christina H Opava, Ingrid E Lundberg, Magnus Bäck
OBJECTIVE: To establish how guided physical activity in patients with rheumatoid arthritis (RA) without known cardiovascular disease affected vascular and cardiac function, and how these two entities were prospectively interconnected in this patient group. METHODS: Prospective substudy of 29 participants in the Physical Activity in RA (PARA) 2010 trial. All subjects were examined at baseline, at year 1 and 2 with measures of pulse wave velocity and arterial augmentation index, as well as echocardiographic evaluation of diastolic parameters and ventricular-arterial coupling...
November 15, 2017: Journal of Internal Medicine
https://www.readbyqxmd.com/read/29142811/carotid-artery-stiffness-and-development-of-hypertension-in-people-with-paraplegia-and-no-overt-cardiovascular-disease-a-7-year-follow-up-study
#17
Olga Vriz, Nicole Bertin, Arianna Ius, Emiliana Bizzarini, Eduardo Bossone, Francesco Antonini-Canterin
Objectives: The aim of this study was to compare arterial stiffness between people with paraplegia and able-bodied persons (ABPs) and to assess cardiovascular markers that may be predictive of the development of arterial hypertension in people with spinal cord injury (SCI). Setting: This study was conducted at rehabilitation Hospital, Udine (Italy). Methods: Fifty-seven patients with SCI were prospectively enrolled and compared with 88 healthy ABPs...
October 2017: Journal of Cardiovascular Echography
https://www.readbyqxmd.com/read/29142490/postoperative-elevated-resistive-indices-do-not-predict-hepatic-artery-thrombosis-in-extended-criteria-donor-livers
#18
Eric J Siskind, Fauzia Vandermeer, Tamar R Siskind, David A Bruno, Samuel Sultan, Josue Alvarez-Casas, Arielle Stafford, Barton Lane, John C Lamattina, Rolf N Barth, Steven I Hanish
Postoperative transplant liver ultrasounds were analyzed in standard criteria donor (SCD), extended criteria donor (ECD), and donation after cardiac death (DCD) liver allografts to determine if elevated resistive indices (RIs) are consistently present and if they are pathological. Postoperative transplant liver ultrasounds were reviewed from 115 consecutive patients. Hepatic arterial RIs were stratified based on the type of donor: DCD, macrosteatosis (>30%), or standard criteria. In all patients with elevated RI, subsequent ultrasounds were reviewed to demonstrate RI normalization...
December 2017: International Journal of Angiology: Official Publication of the International College of Angiology, Inc
https://www.readbyqxmd.com/read/29131886/determinant-factors-for-arterial-hemodynamics-in-hypertension-theoretical-insights-from-a-computational-model-based-study
#19
Fuyou Liang, Debao Guan, Jordi Alastruey
Hypertension is a well-documented predictive factor for cardiovascular events. Clinical studies have extensively demonstrated the differential hemodynamic consequences of various anti-hypertensive drugs, but failed to clearly elucidate the underlying mechanisms due to the difficulty in performing a quantitative deterministic analysis based on clinical data that carry confounding information stemming from inter-patient differences and the nonlinearity of cardiovascular hemodynamics. In the present study, a multi-scale model of the cardiovascular system was developed to quantitatively investigate the relationships between hemodynamic variables and cardiovascular properties under hypertensive conditions, aiming to establish a theoretical basis for assisting in the interpretation of clinical observations or optimization of therapy...
November 13, 2017: Journal of Biomechanical Engineering
https://www.readbyqxmd.com/read/29129735/arterial-stiffness-and-cerebral-hemodynamic-pulsatility-during-cognitive-engagement-in-younger-and-older-adults
#20
Kevin S Heffernan, Jacqueline A Augustine, Wesley K Lefferts, Nicole L Spartano, William E Hughes, Randall S Jorgensen, Brooks B Gump
This study examined central artery stiffness and hemodynamic pulsatility during cognitive engagement in younger and older adults. METHODS: Vascular-hemodynamic measures were completed in 19 younger (age 35±1yrs) and 20 older (age 69±2yrs) adults at rest and during a Stroop task. Aortic stiffness (carotid-femoral pulse wave velocity, PWV) and carotid pulse pressure (PP) were assessed using applanation tonometry. Carotid stiffness was assessed as a single-point PWV using Doppler Ultrasound...
November 10, 2017: Experimental Gerontology
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