Read by QxMD icon Read

Arterial stiffness

Despina Karasavvidou, Pierre Boutouyrie, Rigas Kalaitzidis, Hakim Kettab, Kosmas Pappas, Dimitrios Stagikas, Nikolaos Antonakis, Dimitrios Tsalikakis, Moses Elisaf, Stephane Laurent
In the general population aortic stiffening, assessed by carotid femoral pulse wave velocity (cf-PWV), is associated with cognitive dysfunction (CO/DY). Data in chronic kidney disease (CKD) are limited. This study tests the hypothesis that large artery stiffness and microvascular damage in CKD patients are related to the damage of brain microcirculation reflected by impaired cognitive function. A cross-sectional study enrolled 151 patients (mean age 58.4 years; 64.5% males; 44 patients with CKD stage 1; 47 with stage 2; 25 with stage 3; and 35 with stage 4)...
July 14, 2018: Journal of Clinical Hypertension
Alireza Rezvani-Sharif, Mohammad Tafazzoli-Shadpour, Alberto Avolio
Atherosclerosis is a major risk factor for cardiovascular disease. However, mechanisms of interaction of atherosclerotic plaque development and local stiffness of the lamellar structure of the arterial wall are not well established. In the current study, the local Young's modulus of the wall and plaque components were determined for three different groups of healthy, mildly diseased and advanced atherosclerotic human abdominal aortas. Histological staining was performed to highlight the atherosclerotic plaque components and lamellar structure of the aortic media, consisting of concentric layers of elastin and interlamellar zones...
July 13, 2018: Cardiovascular Engineering and Technology
Tatsuya Maruhashi, Junko Soga, Noritaka Fujimura, Naomi Idei, Shinsuke Mikami, Yumiko Iwamoto, Akimichi Iwamoto, Masato Kajikawa, Takeshi Matsumoto, Nozomu Oda, Shinji Kishimoto, Shogo Matsui, Haruki Hashimoto, Yoshiki Aibara, Farina Mohamad Yusoff, Takayuki Hidaka, Yasuki Kihara, Kazuaki Chayama, Kensuke Noma, Ayumu Nakashima, Chikara Goto, Hirofumi Tomiyama, Bonpei Takase, Takahide Kohro, Toru Suzuki, Tomoko Ishizu, Shinichiro Ueda, Tsutomu Yamazaki, Tomoo Furumoto, Kazuomi Kario, Teruo Inoue, Shinji Koba, Kentaro Watanabe, Yasuhiko Takemoto, Takuzo Hano, Masataka Sata, Yutaka Ishibashi, Koichi Node, Koji Maemura, Yusuke Ohya, Taiji Furukawa, Hiroshi Ito, Hisao Ikeda, Akira Yamashina, Yukihito Higashi
BACKGROUND: The usefulness of vascular function tests for management of patients with a history of coronary artery disease is not fully known. METHODS AND RESULTS: We measured flow-mediated vasodilation (FMD) and brachial-ankle pulse wave velocity (baPWV) in 462 patients with coronary artery disease for assessment of the predictive value of FMD and baPWV for future cardiovascular events in a prospective multicenter observational study. The first primary outcome was coronary events, and the second primary outcome was a composite of coronary events, stroke, heart failure, and sudden death...
July 12, 2018: Journal of the American Heart Association
Michal Schafer, Neil Wilson, D Dunbar Ivy, Richard Ing, Steven H Abman, Lorna Browne, Gareth Morgan, Michael Ross, Daniel McLennan, Alex Barker, Brian Fonseca, Michael Di Maria, Kendall S Hunter, Uyen Truong
The purpose of this study was to characterize the pulmonary vascular stiffness using wave intensity analysis (WIA) in children with pulmonary arterial hypertension (PAH), compare the WIA indices with catheterization and MRI derived hemodynamics, and assess the prognostic ability of WIA derived biomarkers to predict the functional worsening. WIA was performed in children with PAH (n=40) and healthy controls (n=15) from phase-contrast MRI derived flow and area waveforms in the main pulmonary artery. From comprehensive WIA spectra, we collected and compared with healthy controls forward compression waves (FCW), backward compression waves (BCW), forward decompression waves (FDW), and wave propagation speed (c-MPA)...
July 13, 2018: American Journal of Physiology. Heart and Circulatory Physiology
Soo Ji Jeon, Hae-Young Lopilly Park, Jae Hyung Lee, Chan Kee Park
Retinal nerve fiber layer (RNFL) loss in diabetic patients is especially common regardless of diabetic retinopathy (DR). The correlations between nonglaucomatous RNFL loss and systemic characteristics in diabetic patients have aroused interests in many aspects. 167 subjects with type 2 diabetes who underwent evaluation for arterial stiffness and cardiovascular autonomic function using heart rate variability (HRV) were included in this study. Arterial stiffness was measured using cardio-ankle vascular index (CAVI) and ankle-brachial index (ABI)...
July 12, 2018: Scientific Reports
Ka Ying Bonnie Ng, Nigel A B Simpson, Janet E Cade, Darren C Greenwood, Harry J Mcardle, Etienne Ciantar, Nisreen A Alwan
BACKGROUND: In adults, arterial stiffness measured by pulse wave velocity (PWV) is regarded as a predictor of cardiovascular disease. Infant vascular development depends on factors related to pregnancy, including maternal blood pressure (BP). This study assessed the association between maternal BP in pregnancy and infant brachio-femoral PWV at age 2-6 weeks. METHODS: The Baby Vascular health and Iron in Pregnancy (Baby VIP) study is a birth cohort which measured PWV and heart rate (HR) in 284 babies in Leeds, UK, at 2-6 weeks after birth...
2018: PloS One
Hossein Mohammadi, Simon Lessard, Eric Therasse, Rosaire Mongrain, Gilles Soulez
Endovascular aneurysm repair is rapidly emerging as the primary preferred method for treating abdominal aortic aneurysm. In this image-guided interventional procedure, to obtain the roadmap and decrease contrast injections, preoperative CT images are overlaid onto live fluoroscopy images using various 2D/3D image fusion techniques. However, the structural changes due to the insertion of stiff tools degrade the fusion accuracy. To correct the mismatch and quantify the intraoperative deformations, we present a patient-specific biomechanical model of the aorto-iliac structure and its surrounding tissues...
July 11, 2018: Annals of Biomedical Engineering
Dong-Hui Ao, Fei-Fei Zhai, Fei Han, Li-Xin Zhou, Jun Ni, Ming Yao, Ding-Ding Zhang, Ming-Li Li, Xiao-Hong Fan, Zheng-Yu Jin, Li-Ying Cui, Shu-Yang Zhang, Yi-Cheng Zhu
Background: Recent studies have shown that renal disease is associated with magnetic resonance imaging (MRI) markers of cerebral small vessel disease (CSVD), independent of traditional vascular risk factors. Although large artery lesions might be involved in the cerebrorenal association, evidence has been lacking. Methods: A total of 928 participants from a population-based cohort study were included. Kidney injury measurements included urinary albumin-to-creatinine ratio (ACR) and estimated glomerular filtration rate (eGFR)...
2018: Frontiers in Neurology
Benjamin E Levy, Md Murad Hossain, Justin M Sierchio, Diwash Thapa, Caterina M Gallippi, Amy L Oldenburg
Direct ultrasonic imaging of arterial and venous thrombi could aid in diagnosis and treatment planning by providing rapid and cost-effective measurements of thrombus volume and elastic modulus. Toward this end, it was demonstrated that open-air magnetomotive ultrasound (MMUS) provides specific contrast to superparamagnetic iron oxide (SPIO)-labelled model thrombi embedded in gelatin-based blood vessel-mimicking flow phantoms. MMUS was performed on model thrombi in the presence of pulsatile flow that mimics cardiac-induced motion found in real vasculature...
May 28, 2018: IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control
Mark Butlin, Fatemeh Shirbani, Edward Barin, Isabella Tan, Bart Spronck, Alberto Avolio
OBJECTIVE: Measuring arterial pulse transit time (PTT) to estimate blood pressure (BP) without conventional brachial cuff-based measurement is not new, but is a focus of current wearable technologies research. Much research pertains to efficient, accurate sensing of artery-related waveforms, yet the relationship between PTT and BP receives less attention despite being key for accurate BP estimation. This study investigated BP/PTT calibration by quantifying anatomical site variability (n=10, 3 female, age 309 years) and individual variability (n=103, 50 female, age 5322 years)...
April 5, 2018: IEEE Transactions on Bio-medical Engineering
Zorana Vasiljevic, Gordana Krljanac, Marija Zdravkovic, Ratko Lasica, Danijela Trifunovic, Milika Asanin
BACKGROUND: The heart failure with preserved ejection fraction (HFpEF) is defined as the preserved left ventricular ejection fraction (LVEF) with the signs of heart failure, elevated natriuretic peptides, and either the evidence of the structural heart disease or diastolic dysfunction. The importance of this form of heart failure was increased after studies where the mortality rates and readmission to the hospital were founded similar as in patients with HF and reduced EF (HFrEF). Coronary microvascular ischemia, cardiomyocyte injury and stiffness could be an important factors in the pathophysiology of HFpEF...
July 11, 2018: Current Pharmaceutical Design
Kenneth Yong, Trevor Mori, Gerard Chew, Lawrence J Beilin, Ian Puddey, Gerald Watts, Gursharan Dogra, Neil Boudville, Wai Lim
INTRODUCTION: Diastolic dysfunction (DD) is an important cause of cardiovascular disease (CVD) mortality in chronic kidney disease (CKD) patients. Non-traditional risk factors such as arterial stiffness and inflammation are implicated in the pathogenesis of DD in CKD patients. AIM: To determine the association between inflammatory markers [interleukin(IL)-12, IL-18, highly sensitive C-reactive protein (hsCRP)] and non-invasive markers of arterial stiffness [24-hour pulse pressure (PP)] with DD in stage 3-4 CKD patients...
July 10, 2018: Internal Medicine Journal
Albane B R Maggio, Nathalie J Farpour-Lambert, Yacine Aggoun, Katia Galan, Fabrizio Montecucco, François Mach, Maurice Beghetti
BACKGROUND: Childhood obesity is associated with premature cardiovascular complications. However, little is known about the effect of a family-based behavioral intervention on the relationship between arterial function, blood pressure and biomarkers in pre-pubertal children with obesity. DESIGN: This was a single center randomized controlled trial (RCT) including 74 children randomized to a 6-month behavioral intervention to treat obesity. In 48 children (13 controls and 35 interventions), we assessed: serum level of cytokine (CCL2), adiponectin, and neutrophil product (MMP-8), as well as carotid intima-media thickness, flow-mediated dilation (FMD), nitroglycerin-mediated dilation; arterial stiffness (incremental elastic modulus, Einc), pulse wave velocity (PWV), resting and 24-hour blood pressure (BP)...
July 10, 2018: European Journal of Clinical Investigation
Pauline Vanderweckene, Laurent Weekers, Patrizio Lancellotti, François Jouret
Arteriovenous fistula (AVF) is regarded as the best vascular access for chronic haemodialysis (HD). Still, AVF inherently causes significant haemodynamic changes. Although the necessity for vascular access despite its putative cardiovascular complications favours AVF creation in patients under chronic HD, one may question whether sustaining a functional AVF after successful kidney transplantation extends the haemodynamic threat. Small prospective series suggest that AVF ligation causes rapid and sustained reduction in left ventricular hypertrophy...
June 2018: Clinical Kidney Journal
Juhyun Song, So Ra Yoon, Oh Yoen Kim
Background: Low adiponectin levels are associated with increased insulin resistance (IR) and arterial stiffness in hypertensive patients, but higher adiponectin levels are also found in heart failure patients. This discrepancy has not been fully resolved, but it may be related to the adiponectin gene ( ADIPOQ ) which regulates adiponectin production. We aimed to investigate whether the relationship between adiponectin and arterial stiffness is associated with ADIPOQ rs1501299 G/T polymorphism in nondiabetic Korean men...
2018: Diabetology & Metabolic Syndrome
Martin Chaumont, Benjamin de Becker, Wael Zaher, Antoine Culié, Guillaume Deprez, Christian Mélot, Florence Reyé, Pierre Van Antwerpen, Cédric Delporte, Nadia Debbas, Karim Zouaoui Boudjeltia, Philippe van de Borne
Propylene glycol and glycerol are electronic cigarettes vehicles allowing liquid vaporization and nicotine transport. The respective effects of these different constituents on the cardiovascular system are unknown. We assessed the differential effects of vehicles (propylene glycol and glycerol) and nicotine on microcirculatory function, arterial stiffness, hemodynamic parameters and oxidative stress. Twenty-five tobacco smokers were exposed to vaping with and without nicotine, and sham vaping, in a randomized, single blind, 3-period crossover design study...
July 10, 2018: Scientific Reports
Jennifer H Jordan, Sharon M Castellino, Giselle C Meléndez, Heidi D Klepin, Leslie R Ellis, Zanetta Lamar, Sujethra Vasu, Dalane W Kitzman, William O Ntim, Peter H Brubaker, Nathaniel Reichek, Ralph B D'Agostino, W Gregory Hundley
BACKGROUND: Myocardial atrophy and left ventricular (LV) mass reductions are associated with fatigue and exercise intolerance. The relationships between the receipt of anthracycline-based chemotherapy (Anth-bC) and changes in LV mass and heart failure (HF) symptomatology are unknown, as is their relationship to LV ejection fraction (LVEF), a widely used measurement performed in surveillance strategies designed to avert symptomatic HF associated with cancer treatment. METHODS AND RESULTS: We performed blinded, serial assessments of body weight, LVEF and mass, LV-arterial coupling, aortic stiffness, and Minnesota Living with Heart Failure Questionnaire measures before and 6 months after initiating Anth-bC (n=61) and non-Anth-bC (n=15), and in 24 cancer-free controls using paired t and χ2 tests and multivariable linear models...
July 2018: Circulation. Heart Failure
Sahar El Shedoudy, Eman El-Doklah
Objectives: To evaluate the safety of using the stiff end of a coronary wire to perforate an atretic pulmonary valve (PV) in patients with pulmonary atresia with intact ventricular septum (PAIVS). Background: Radiofrequency perforation is an accepted modality to perforate the PV in patients PAIVS. However, the high cost precludes its widespread use. Patients and methods: This is a single-center experience that spanned from March 2013 to January 2016 and involved 13 neonates who were severely cyanotic with PAIVS and with ductal-dependent pulmonary circulation...
July 2018: Journal of the Saudi Heart Association
Edoardo Melilli, Anna Manonelles, Nuria Montero, Josep Grinyo, Alberto Martinez-Castelao, Oriol Bestard, Josep Cruzado
Arterial stiffness is a biologic process related to ageing and its relationship with cardiovascular risk is well established. Several methods are currently available for non-invasive measurement of arterial stiffness that provide valuable information to further assess patients' vascular status in real time. In kidney transplantation recipients, several factors could accelerate the stiffness process, such as the use of calcineurin inhibitors (CNIs), the presence of chronic kidney disease and other classical cardiovascular factors, which would explain, at least in part, the high cardiovascular mortality and morbidity...
June 2018: Clinical Kidney Journal
Masanari Kuwabara, Mehmet Kanbay, Ichiro Hisatome
No abstract text is available yet for this article.
July 9, 2018: Hypertension
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"