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Arterial stiffness

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https://www.readbyqxmd.com/read/27908892/resting-heart-rate-trajectory-pattern-predicts-arterial-stiffness-in-a-community-based-chinese-cohort
#1
Shuhua Chen, Weijuan Li, Cheng Jin, Anand Vaidya, Jingli Gao, Hui Yang, Shouling Wu, Xiang Gao
OBJECTIVE: To examine whether the long-term resting heart rate (RHR) pattern can predict the risk of having arterial stiffness in a large ongoing cohort study. APPROACH AND RESULTS: This community-based cohort included 12 554 participants in the Kailun study, who were free of myocardial infarction, stroke, arrhythmia, and cancer. We used latent mixture modeling to identify RHR trajectories in 2006, 2008, and 2010. We used multivariate linear regression model to examine the association between RHR trajectory patterns and the risk of having arterial stiffness, which was assessed by brachial-ankle pulse wave velocity in 2010 to 2016...
December 1, 2016: Arteriosclerosis, Thrombosis, and Vascular Biology
https://www.readbyqxmd.com/read/27908486/an-inverse-method-to-determine-arterial-stiffness-with-guided-axial-waves
#2
Guo-Yang Li, Qiong He, Lin Jia, Ping He, Jianwen Luo, Yanping Cao
Many cardiovascular diseases can alter arterial stiffness; therefore, measurement of arterial wall stiffness can provide valuable information for both diagnosis of such diseases in the clinic and evaluation of the effectiveness of relevant drugs. However, quantitative assessment of the in vivo elastic properties of arterial walls in a non-invasive manner remains a great challenge. In this study, we found that the elastic modulus of the arterial wall can be extracted from the dispersion curve of the guided axial wave (GAW) measured using the ultrasound elastography method...
November 28, 2016: Ultrasound in Medicine & Biology
https://www.readbyqxmd.com/read/27906841/annexin-a5-in-treated-hypertensive-patients-and-its-association-with-target-organ-damage
#3
Alessandro Maloberti, Paolo Meani, Paola Vallerio, Marisa Varrenti, Francesca Casadei, Francesco Musca, Rita Facchetti, Anna M Di Blasio, Susanna Ravassa, Giuseppe Mancia, Cristina Giannattasio
OBJECTIVE: Annexin A5 (AnxA5) has been previously linked to the presence of carotid and cardiac target organ damage (TOD) in the context of heart failure and rheumatologic patients. However, information is scant in the context of hypertension. Aim of our study was to evaluate AnxA5 in treated hypertension patients compared with normotensive controls and to determine whether it is associated with vascular and heart TOD evaluated as arterial stiffness, carotid plaque and left ventricular hypertrophy...
January 2017: Journal of Hypertension
https://www.readbyqxmd.com/read/27906838/arterial-stiffness-index-beta-and-cardio-ankle-vascular-index-inherently-depend-on-blood-pressure-but-can-be-readily-corrected
#4
Bart Spronck, Alberto P Avolio, Isabella Tan, Mark Butlin, Koen D Reesink, Tammo Delhaas
OBJECTIVES: Arterial stiffness index β and cardio-ankle vascular index (CAVI) are widely accepted to quantify the intrinsic exponent (β0) of the blood pressure (BP)-diameter relationship. CAVI and β assume an exponential relationship between pressure (P) and diameter (d). We aim to demonstrate that, under this assumption, β and CAVI as currently implemented are inherently BP-dependent and to provide corrected, BP-independent forms of CAVI and β. METHODS AND RESULTS: In P = Prefe, usually reference pressure (Pref) and reference diameter (dref) are substituted with DBP and diastolic diameter to accommodate measurements...
January 2017: Journal of Hypertension
https://www.readbyqxmd.com/read/27905124/assessment-of-early-atherosclerosis-and-left-ventricular-dysfunction-in-children-with-21-hydroxylase-deficiency
#5
Rahmi Özdemir, Hüseyin Anil Korkmaz, Mehmet Küçük, Cem Karadeniz, Timur Meşe, Behzat Özkan
AIM: We analysed 25 children with 21-hydroxylase deficiency who received glucocorticoid and/or mineralocorticoid treatment for at least 12 months to determine the effects of the disease and its treatment on vascular structures and ventricular function. METHODS: Twenty-five patients with 21-hydroxylase-deficient congenital adrenal hyperplasia (CAH) and 25 control subjects were enrolled into this observational, cross-sectional study. The patients were investigated in terms of fasting blood glucose and insulin; fasting serum lipid profile; serum 17-hydroxyprogesterone; dehydroepiandrosterone sulphate; androstenedione; and adrenocorticotropic hormone...
November 7, 2016: Clinical Endocrinology
https://www.readbyqxmd.com/read/27904026/inverse-relationship-between-sleep-duration-and-cardio-ankle-vascular-index-in-children
#6
Noriteru Morita, Isao Kambayashi, Tomoyasu Okuda, Shiro Oda, Shingo Takada, Toshihiro Nakajima, Noriyuki Shide, Hisashi Shinkaiya, Koichi Okita
AIM: Poor sleep has been shown to be associated with the development of cardiovascular risk factors, such as obesity, in both adults and children. This study aimed to investigate the relationship between sleep duration and arterial stiffness indices in Japanese children and early adolescents. METHODS: The data on 102 students (56 males, 46 females; mean age, 11.9±1.8 years) were analyzed. As non-invasive arterial stiffness parameters, the cardio-ankle vascular index (CAVI) and heart-ankle pulse wave velocity (haPWV) were evaluated...
December 1, 2016: Journal of Atherosclerosis and Thrombosis
https://www.readbyqxmd.com/read/27902626/a-lesson-in-vigilance-pressure-dependency-of-a-presumed-pressure-independent-index-of-arterial-stiffness
#7
Patrick Segers
No abstract text is available yet for this article.
January 2017: Journal of Hypertension
https://www.readbyqxmd.com/read/27900498/central-hemodynamics-and-arterial-stiffness-in-idiopathic-and-multiple-system-atrophy
#8
Klaas Franzen, Sabine Fliegen, Jelena Koester, Rafael Campos Martin, Günther Deuschl, Michael Reppel, Kai Mortensen, Susanne A Schneider
Blood pressure is commonly abnormal in parkinsonian disorders, but central hemodynamics and arterial stiffness, well-established predictors of total cardiovascular risk, have rarely been studied in these disorders. 32 patients [27 with idiopathic Parkinson's disease (iPD); 5 with multiple system atrophy (MSA)] and 15 controls matched for cardiac risk factors underwent 24 h-ambulatory blood pressure recordings using an I.E.M. device (Mobil-O-Graph™), measuring peripheral pressure and calculating central pressures and arterial stiffness...
November 29, 2016: Journal of Neurology
https://www.readbyqxmd.com/read/27900165/evaluation-of-cardiovascular-risk-lowering-health-benefits-accruing-from-laboratory-based-community-based-and-exercise-referral-exercise-programmes
#9
R Webb, J E S Thompson, J-S Ruffino, N A Davies, L Watkeys, S Hooper, P M Jones, G Walters, D Clayton, A W Thomas, K Morris, D H Llewellyn, M Ward, J Wyatt-Williams, B J McDonnell
BACKGROUND: To evaluate the ability of community-based exercise programmes to facilitate public participation in exercise and hence improved cardiovascular health, we assessed the respective impacts of: a continuously monitored exercise programme based within our university (study 1); a Valleys Regional Park-facilitated community-based outdoor exercise programme (study 2); a Wales National Exercise Referral Scheme-delivered exercise-referral programme (study 3). METHODS: Biomolecular (monocytic PPARγ target gene expression), vascular haemodynamic (central/peripheral blood pressure, arterial stiffness), clinical (insulin sensitivity, blood lipids) and anthropometric (body mass index, waist circumference, heart rate) parameters were investigated using RT-PCR, applanation tonometry, chemical analysis and standard anthropometric techniques...
2016: BMJ Open Sport & Exercise Medicine
https://www.readbyqxmd.com/read/27899739/impact-of-immune-deficiency-on-remodeling-of-maternal-resistance-vasculature-4-weeks-postpartum-in-mice
#10
Elizabeth A Bonney, Ann Howard, Kendall Krebs, Kelly Begin, Kelsey Veilleux, Natalia I Gokina
Pregnancy manifests changes in the vascular and immune systems that persist postpartum (PP), have important implications for future pregnancies, and may modify responses to cardiovascular stress in late life. The association between immune and vascular function and the generation or progression of cardiovascular disease beg the question of whether altered immunity modifies pregnancy-induced changes in the vasculature. Our objective was to compare changes in the function and remodeling of systemic resistance vessels 4 weeks PP in normal C57BL/6 (B6), and immunodeficient mice recombinase 1-deficient/B6 (Rag1(-/-))...
November 28, 2016: Reproductive Sciences
https://www.readbyqxmd.com/read/27898844/static-and-dynamic-components-of-right-ventricular-afterload-are-negatively-associated-with-calf-survival-at-high-altitude
#11
J M Neary, R D Brown, T N Holt, K R Stenmark, R M Enns, M G Thomas, F B Garry
The purposes of this study were to evaluate mean, systolic, and diastolic pulmonary arterial pressures; pulmonary arterial pulse pressures; and systemic oxygen extraction fraction as risk factors for the survival of suckling calves on one ranch located at an altitude of ≥ 2,730 m in Colorado, USA. A prospective cohort study of 58 calves was performed. Pulmonary arterial pressures and systemic oxygen extraction were measured when calves were approximately 3 mo (86 ± 7 d) and 7 mo (197 ± 6 d) of age. Seven of the 58 calves (12%), 4 steers and 3 heifers, were unaccounted for and presumed dead between 3 and 7 mo of age...
October 2016: Journal of Animal Science
https://www.readbyqxmd.com/read/27898644/-letter-to-the-editor-of-response-for-arterial-stiffness-in-patients-with-celiac-disease
#12
Hüseyin Korkmaz, Levent Kebapcilar
No abstract text is available yet for this article.
January 2017: European Journal of Gastroenterology & Hepatology
https://www.readbyqxmd.com/read/27898424/arterial-stiffness-as-a-cardiovascular-risk-factor-in-stage-5d-chronic-kidney-disease-patients-an-age-affair
#13
Carmine Zoccali, Francesca Mallamaci
No abstract text is available yet for this article.
November 30, 2016: American Journal of Nephrology
https://www.readbyqxmd.com/read/27898419/high-pulse-wave-velocity-defines-a-very-high-cardiovascular-risk-cohort-of-dialysis-patients-under-age-60
#14
João Pedro Ferreira, Nicolas Girerd, Bruno Pannier, Patrick Rossignol, Gerard M London
BACKGROUND: Patients with end-stage renal disease (ESRD) are at a high risk of cardiovascular mortality (CVM). In patients with ESRD, arterial stiffness increases at an earlier age when compared to the general population and this contributes to the overall risk of cardiovascular mortality. The main objective of this study was to clarify the interplay between age and cardiovascular alterations in ESRD. METHODS: Prospective, observational cohort study initiated in April 1987 until the end of 1998 with events recorded until the end of the year 2000 at the F...
November 30, 2016: American Journal of Nephrology
https://www.readbyqxmd.com/read/27897608/modulating-oxidative-stress-and-inflammation-in-elders-the-moxie-study
#15
Amy Cameron Ellis, Tanja Dudenbostel, Julie L Locher, Kristi Crowe-White
Cardiovascular disease (CVD) is the leading cause of death among women in the United States. Endothelial dysfunction and arterial stiffness increase with advancing age and are early predictors of future CVD outcomes. We designed the Modulating Oxidative Stress and Inflammation in Elders (MOXIE) study to examine the effects of 100% watermelon juice as a "food-first" intervention to reduce CVD risk among African American (AA) and European American (EA) women aged 55-69 years. Vascular dysfunction is more pronounced in AA compared to EA women due in part to lower nitric oxide bioavailability caused by higher oxidative stress...
October 2016: Journal of Nutrition in Gerontology and Geriatrics
https://www.readbyqxmd.com/read/27897440/association-between-aerobic-exercise-training-effects-of-serum-adropin-level-arterial-stiffness-and-adiposity-in-obese-elderly-adults
#16
Shumpei Fujie, Natsuki Hasegawa, Toshiyuki Kurihara, Kiyoshi Sanada, Takafumi Hamaoka, Motoyuki Iemitsu
Serum levels of adropin, which enhances endothelial cell release of nitric oxide (NO), are lower in obese patients. Although habitual aerobic exercise reduces arterial stiffness and adiposity, the relationship between these effects and circulating levels of adropin remains unclear. The purpose of this study was to determine if serum adropin level is associated with the effects of aerobic exercise training on arterial stiffness and adiposity in obese adults. In Experiment 1, we examined whether serum adropin levels are associated with cardiorespiratory fitness, carotid β-stiffness, plasma nitrite/nitrate (NOx) level, and abdominal visceral fat in 27 normal, 20 overweight, and 25 obese adults (age, 41-79 years)...
September 13, 2016: Applied Physiology, Nutrition, and Metabolism, Physiologie Appliquée, Nutrition et Métabolisme
https://www.readbyqxmd.com/read/27891374/effect-of-enhanced-external-counter-pulsation-treatment-on-aortic-blood-pressure-arterial-stiffness-and-ejection-fraction-in-patients-with-coronary-artery-disease
#17
Ramasamy Subramanian, Sushma Nayar, Chokkalingam Meyyappan, N Ganesh, Arumugam Chandrakasu, Pradeep G Nayar
INTRODUCTION: Enhanced External Counter Pulsation (EECP) is a non-invasive treatment option for patients with Coronary Artery Disease (CAD). The treatment has shown to augment diastolic pressure and reduce Left Ventricular (LV) after-load by reducing systemic vascular resistance. The effect of EECP in standard brachial blood pressure and central haemodynamic parameters are not known. AIM: We hypothesized that EECP may have differential effect in CAD patients with low systolic blood pressure when compared to normal systolic pressure and the mechanism underlying this differential effect may be due to improvement in LV function...
October 2016: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/27885494/comparison-of-arterial-stiffness-compliance-in-the-ascending-aorta-and-common-carotid-artery-in-healthy-subjects-and-its-impact-on-left-ventricular-structure-and-function
#18
Olga Vriz, Julien Magne, Caterina Driussi, Gabriele Brosolo, Francesco Ferrara, Paolo Palatini, Victor Aboyans, Eduardo Bossone
Arterial stiffness and compliance parameters from two adjacent elastic arteries [aorta and common carotid artery (CCA)] were compared and their relationship with left ventricular (LV) structure and function and clinical parameters was assessed. 584 healthy subjects were prospectively enrolled [mean age 47.8 ± 18.4 years, range 16-94; 318 (54.4%) men]. They underwent comprehensive transthoracic echocardiography; M-mode diameters were measured at the level of the ascending aorta in systole and diastole and by echo-tracking at the level of the left CCA...
November 24, 2016: International Journal of Cardiovascular Imaging
https://www.readbyqxmd.com/read/27885445/limited-ventricular-preload-is-the-main-reason-for-reduced-stress-reserve-after-atrial-baffle-repair
#19
Andreas Eicken, Julia Michel, Alfred Hager, Daniel Tanase, Harald Kaemmerer, Julie Cleuziou, John Hess, Peter Ewert
The atrial baffle repair (ABR) significantly improved the fate of patients with transposition of the great arteries (TGA). However, these patients show impaired exercise tolerance and some present severe decline of systemic ventricular function. Intrinsic myocardial weakness, low heart rate response to exercise and diastolic filling impairment are discussed to be causative. Forty-nine long-term survivors with TGA (median age 23.7 year) after ABR were catheterized with measured oxygen consumption in four conditions (baseline, volume, atrial pacing, dobutamine) and the results were compared to 10 normal controls...
November 24, 2016: Pediatric Cardiology
https://www.readbyqxmd.com/read/27885058/association-between-human-immunodeficiency-virus-infection-and-arterial-stiffness-in-children
#20
Justin S Kuilder, Nikmah S Idris, Diederick E Grobbee, Michiel L Bots, Michael Mh Cheung, David Burgner, Nia Kurniati, Cuno Spm Uiterwaal
BACKGROUND: Human immunodeficiency virus infection (HIV) is associated with increased cardiovascular risk and adverse cardiovascular outcome in adults. Early recognition of changes in vascular properties might prove essential in cardiovascular prevention in HIV-infected patients. We investigated the relations between HIV infection and arterial stiffness in children. METHODS: This cross-sectional study included 51 HIV-infected and 52 healthy children (age 3.2-14...
November 24, 2016: European Journal of Preventive Cardiology
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