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https://www.readbyqxmd.com/read/28718033/a-new-clinical-trial-of-neoadjuvant-chemotherapy-combined-with-transoral-robotic-surgery-and-customized-adjuvant-therapy-for-patients-with-t3-or-t4-oropharyngeal-cancer
#1
Young Min Park, Chan Min Jung, Dongchul Cha, Da Hee Kim, Hye Ryun Kim, Ki Chang Keum, Nam Hoon Cho, Se-Heon Kim
BACKGROUND: A prospective clinical trial of combination neoadjuvant chemotherapy, transoral robotic surgery (TORS), and customized adjuvant therapy for patients with locally advanced oropharyngeal cancer was conducted. METHODS: Between July 2009 and October 2016, 31 patients were enrolled in this clinical trial. RESULTS: The primary lesions were located in the tonsils of 27 patients and in the base of the tongue of 4 patients. Of the 31 patients, 16 (51...
July 17, 2017: Annals of Surgical Oncology
https://www.readbyqxmd.com/read/28715374/in-vivo-evaluation-of-the-mechanical-and-viscoelastic-properties-of-the-rat-tongue
#2
Emanuele Loro, Stephen H Wang, Richard J Schwab, Tejvir S Khurana
The tongue is a highly innervated and vascularized muscle hydrostat on the floor of the mouth of most vertebrates. Its primary functions include supporting mastication and deglutition, as well as taste-sensing and phonetics. Accordingly, the strength and volume of the tongue can impact the ability of vertebrates to accomplish basic activities such as feeding, communicating, and breathing. Human patients with sleep apnea have enlarged tongues, characterized by reduced muscle tone and increased intramuscular fat that can be visualized and quantified by magnetic resonance imaging (MRI)...
July 6, 2017: Journal of Visualized Experiments: JoVE
https://www.readbyqxmd.com/read/28713745/recovering-breathing-and-feeding-of-a-newborn-with-pierre-robin-sequence
#3
Francisnele Maria de Aquino Fraporti Tomáz, Alvaro Henrique Borges, Alexandre Meireles Borba, Luiz Evaristo Ricci Volpato
Pierre Robin sequence (PRS) is characterized by the triad micrognathia, glossoptosis, and airway obstruction, commonly associated with cleft palate. This study reports the case of a patient with characteristics consistent with the diagnosis of PRS in the 1(st) week of life. To stabilize the airway, oro-tracheal intubation was performed without success, followed by tracheostomy and glossopexy and after a small improvement in symptoms, it was decided to perform the mandibular distraction osteogenesis (MDO). At the age of 6, her maxillofacial development was within expectations, with patent airway, the presence of deciduous teeth, and without neurological impairment...
January 2017: Annals of Maxillofacial Surgery
https://www.readbyqxmd.com/read/28704419/a-pilot-feeding-study-for-adults-with-asthma-the-healthy-eating-better-breathing-trial
#4
Emily P Brigham, Elizabeth C Matsui, Lawrence J Appel, Deborah A Bull, Jean Curtin-Brosnan, Shuyan Zhai, Karen White, Jeanne B Charleston, Nadia N Hansel, Gregory B Diette, Meredith C McCormack
RATIONALE: Evidence from observational studies and to a lesser extent clinical trials suggest that a healthy diet may improve symptoms and lung function in patients with asthma. We conducted a pilot study to determine the feasibility of conducting a larger scale dietary trial and to provide preliminary evidence on the impact of a healthy diet on asthma outcomes. METHODS: In a randomized, two period cross-over trial, participants with asthma received a 4-week dietary intervention followed by a usual diet (or vice versa), separated by a 4-week washout...
2017: PloS One
https://www.readbyqxmd.com/read/28701605/role-of-transesophageal-echocardiography-in-surgical-retrieval-of-embolized-amplatzer-device-and-closure-of-coronary-cameral-fistula
#5
Bhupesh Kumar, Alok Kumar, Ganesh Kumar, Harkant Singh
Congenital coronary artery fistula is an uncommon anomaly. Transcatheter coil embolization or Amplatzer vascular plug device closure of fistula is often done in symptomatic patients with safe accessibility to the feeding coronary artery. Embolization of Amplatzer vascular plug device is rare. We report an 11-year-old male child who presented to us with increasing shortness of breath for 7 years. He had a history of Amplatzer vascular plug device closure of right coronary-cameral fistula 8 years back. Echocardiography demonstrated a dilated aneurysmal right coronary artery with turbulent jet entering into the right ventricle (RV) and device embolized into the left pulmonary artery (LPA)...
July 2017: Annals of Cardiac Anaesthesia
https://www.readbyqxmd.com/read/28700565/nasal-continuous-positive-airway-pressure-influences-bottle-feeding-in-preterm-lambs
#6
Nathalie Samson, Audrey Michaud, Rahmeh Othman, Charlène Nadeau, Stéphanie Nault, Danny Cantin, Michaël Sage, Céline Catelin, Jean-Paul Praud
BACKGROUND: In preterm infants, the time from initiation to full oral feeding can take weeks, which represents a very worrisome problem in neonatal medicine. Although current knowledge suggests that oral feeding should be introduced early, this is often delayed due to the need for prolonged nasal continuous positive airway pressure (nCPAP). Indeed, most caregivers fear that nCPAP could disrupt sucking-swallowing-breathing coordination and induce tracheal aspiration. The goal of the present study was to assess the impact of nCPAP delivered by the Infant Flow System on the physiology of sucking-swallowing-breathing coordination during bottle-feeding in preterm lambs over 24 h...
July 12, 2017: Pediatric Research
https://www.readbyqxmd.com/read/28695252/oil-spills-and-marine-mammals-in-british-columbia-canada-development-and-application-of-a-risk-based-conceptual-framework
#7
Adrianne L Jarvela Rosenberger, Misty MacDuffee, Andrew G J Rosenberger, Peter S Ross
Marine mammals are inherently vulnerable to oil spills. We developed a conceptual framework to evaluate the impacts of potential oil exposure on marine mammals and applied it to 21 species inhabiting coastal British Columbia (BC), Canada. Oil spill vulnerability was determined by examining both the likelihood of species-specific (individual) oil exposure and the consequent likelihood of population-level effects. Oil exposure pathways, ecology, and physiological characteristics were first used to assign species-specific vulnerability rankings...
July 2017: Archives of Environmental Contamination and Toxicology
https://www.readbyqxmd.com/read/28673080/enteral-nutrition-for-preterm-infants-by-bolus-or-continuous-an-update
#8
Valentina Bozzetti, Paolo E Tagliabue
Optimization of nutritional management of preterm infants is crucial for achievement of their long-term health. Enteral nutrition is preferred to total parenteral nutrition (TPN) because the former avoids complications related to vascular catheterization, sepsis, adverse effects of TPN, and fasting. Due to the lack of ability of preterm infants to coordinate suckling, swallowing, and breathing, tube feeding is necessary for most infants less than 1500 g to ensure sufficient feeding tolerance, to support optimal growth and to reduce the risk of aspiration...
June 28, 2017: La Pediatria Medica e Chirurgica: Medical and Surgical Pediatrics
https://www.readbyqxmd.com/read/28672098/inhaled-corticosteroids-in-transient-tachypnea-of-the-newborn-a-randomized-placebo-controlled-study
#9
Yulia Vaisbourd, Bahaa Abu-Raya, Shmuel Zangen, Shmuel Arnon, Arieh Riskin, Irit Shoris, Nael Elias, David Bader, Amir Kugelman
OBJECTIVE: Prenatal corticosteroids were shown to reduce the respiratory complication in late preterm infants. Our objective was to determine if early inhaled corticosteroids could alleviate the respiratory distress and morbidity in late preterm and term neonates with transient tachypnea of the newborn (TTN). STUDY DESIGN: Double-blind, randomized placebo-controlled, multicenter pilot study. Infants born at >34 weeks gestational age with TTN at 4 h of age were randomized to two doses, 12 h apart, of inhaled Budesonide 1000 μg/dose or placebo within 6 h from delivery...
August 2017: Pediatric Pulmonology
https://www.readbyqxmd.com/read/28661414/muscle-mass-and-physical-recovery-in-icu-innovations-for-targeting-of-nutrition-and-exercise
#10
Paul E Wischmeyer, Zudin Puthucheary, Iñigo San Millán, Daniel Butz, Michael P W Grocott
PURPOSE OF REVIEW: We have significantly improved hospital mortality from sepsis and critical illness in last 10 years; however, over this same period we have tripled the number of 'ICU survivors' going to rehabilitation. Furthermore, as up to half the deaths in the first year following ICU admission occur post-ICU discharge, it is unclear how many of these patients ever returned home or a meaningful quality of life. For those who do survive, recent data reveals many 'ICU survivors' will suffer significant functional impairment or post-ICU syndrome (PICS)...
August 2017: Current Opinion in Critical Care
https://www.readbyqxmd.com/read/28635876/-salivation-after-stroke
#11
Z A Zalyalova
Salivation after stroke (sialorrhea, hypersalivation, ptyalism) can be caused by the overproduction or a lack of utilization of saliva. Patients after stroke often have sialorrhea as a result of dysphagia. Neurogenic dysphagia in acute period after stroke occurs in 25-65% of patients. The mortality rate among people with post-stroke dysphagia and tube feeding ranges from 20 to 24%. Patients who suffering from profuse salivation have difficulties with articulation and swallowing, bad breath, irritation and maceration of perioral area, contamination of clothing and bed linen...
2017: Zhurnal Nevrologii i Psikhiatrii Imeni S.S. Korsakova
https://www.readbyqxmd.com/read/28624274/effect-of-nutritional-immunomodulation-and-heat-stress-during-the-dry-period-on-subsequent-performance-of-cows
#12
Thiago F Fabris, Jimena Laporta, Fabiana N Corra, Yazielis M Torres, David J Kirk, Derek J McLean, J D Chapman, Geoffrey E Dahl
Heat stress in dairy cows during the dry period impairs milk yield in the next lactation. Feeding OmniGen-AF (OG; Phibro Animal Health Corp., Teaneck, NJ) to lactating cows during heat stress may increase dry matter intake (DMI) and lowers respiration rate (RR) and rectal temperature (RT), but the effects in dry cows are not known. We hypothesized that OG supplementation before, during, and after the dry period (approximately 160 d total) would overcome the effects of heat stress and improve cow performance in the next lactation...
June 14, 2017: Journal of Dairy Science
https://www.readbyqxmd.com/read/28590549/association-between-breast-feeding-and-paediatric-sleep-disordered-breathing-a-systematic-review
#13
REVIEW
Cecilia Ponce-Garcia, Ivonne Angelica Hernandez, Paul Major, Carlos Flores-Mir
BACKGROUND: Breast feeding has been suggested as a potential protective factor against childhood snoring and sleep disordered breathing (SDB). SDB can have major health consequences. The objective of this systematic review is to synthesise the available literature concerning any potential association between infant feeding methods and SDB in young children. METHODS: Five electronic databases were searched. All searches were inclusive until August 5, 2016. Two authors independently reviewed potentially relevant articles for eligibility...
June 7, 2017: Paediatric and Perinatal Epidemiology
https://www.readbyqxmd.com/read/28586692/functional-innovations-and-the-conquest-of%C3%A2-the%C3%A2-oceans-by-acanthomorph-fishes
#14
REVIEW
Peter C Wainwright, Sarah J Longo
The world's oceans are home to many fantastic creatures, including about 16,000 species of actinopterygian, or ray-finned, fishes. Notably, 85% of marine fish species come from a single actinopterygian subgroup, the acanthomorph or spiny-rayed fishes. Here, we review eight functional innovations found in marine acanthomorphs that have been instrumental in the adaptive radiation of this group in the marine realm. Jaw protrusion substantially enhances the suction feeding mechanism found in all fish. Fin spines serve as a major deterrent to predators and enhance the locomotor function of fins...
June 5, 2017: Current Biology: CB
https://www.readbyqxmd.com/read/28577340/abnormal-growth-and-feeding-behavior-persist-after-removal-of-upper-airway-obstruction-in-juvenile-rats
#15
Mohammad H Assadi, Elena Shknevsky, Yael Segev, Ariel Tarasiuk
Pediatric obstructive sleep-disordered breathing is associated with growth retardation, but also with obesity that has a tendency to persist following treatment. We investigated the effect of upper airways obstruction (AO) and of obstruction removal (OR) in juvenile rats on gut-derived ghrelin and related hypothalamic factors, feeding, and growth hormone (GH) homeostasis. Here, we show that after seven weeks of AO, animals gained less weight compared to controls, despite an increase in food intake due to elevated ghrelin and hypothalamic feeding factors...
June 2, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28566868/oral-subcutaneous-midline-leiomyomatous-hamartoma-presenting-as-congenital-incisive-papilla-overgrowth-in-a-toddler
#16
Ashish Loomba, Shalini Garg, Abhishek Dhindsa, Harshaminder Kaur, Neetu Jain, Promila Dhindsa
Congenital soft-tissue tumors of oral cavity are mostly hyperplastic and benign in nature. This article presents an unusual case of congenital subcutaneous hamartoma of incisive papilla in a 2-year-old female child causing feeding and breathing difficulty. Total excisional biopsy was done under local anesthesia. Histopathology of tissue in reticulin-stained slide showed the presence of immature muscle fibers whereas Masson's trichrome stain revealed collagen fibers and smooth muscles confirming the diagnosis of oral midline subcutaneous smooth muscle (leiomyomatous) hamartoma of incisive papilla...
January 2017: Contemporary Clinical Dentistry
https://www.readbyqxmd.com/read/28542424/development-of-behavioural-profile-in-the-northern-common-boa-boa-imperator-repeatable-independent-traits-or-personality
#17
Olga Šimková, Petra Frýdlová, Barbora Žampachová, Daniel Frynta, Eva Landová
Recent studies of animal personality have focused on its proximate causation and ecological and evolutionary significance in particular, but the question of its development was largely overlooked. The attributes of personality are defined as between-individual differences in behaviour, which are consistent over time (differential consistency) and contexts (contextual generality) and both can be affected by development. We assessed several candidates for personality variables measured in various tests with different contexts over several life-stages (juveniles, older juveniles, subadults and adults) in the Northern common boa...
2017: PloS One
https://www.readbyqxmd.com/read/28508559/two-weeks-of-repetitive-gut-challenge-reduces-exercise-associated-gastrointestinal-symptoms-and-malabsorption
#18
Atlanta Miall, Anthony Khoo, Christopher Rauch, Rhiannon Snipe, Vera Camões-Costa, Peter R Gibson, Ricardo J S Costa
Debilitating gastrointestinal symptoms are a common feature of endurance running, and may be exacerbated by and (or) limit the ability to tolerate carbohydrate intake during exercise. The study aimed to determine whether two weeks of repetitive gut-challenge during running can reduce exercise associated gastrointestinal symptoms and carbohydrate malabsorption. Endurance runners (n= 18) performed an initial gut-challenge trial (GC1) comprising 2 h running exercise at 60% VO2max (steady state) whilst consuming a formulated gel-disc containing 30 g carbohydrates (2:1 glucose-fructose, 10% w/v) every 20 min, followed by a 1 h running effort bout...
May 16, 2017: Scandinavian Journal of Medicine & Science in Sports
https://www.readbyqxmd.com/read/28482381/-nasal-continuous-positive-airway-pressure-ventilation-in-children-with-community-acquired-pneumonia-under-five-years-of-age-a-prospective-multi-center-clinical-study
#19
J Liu, Q Wang, S Y Qian, W M Xu, L L Li, L M Ning, X X Ren, F Lyu, Y B Cheng, L J Gao, C F Liu, W Xu, L Pei, G P Lu, W M Chen
Objective: To analyze the clinical characteristics of community-acquired pneumonia (CAP) in children under five years of age and analyze the safety and efficiency of nasal continuous positive airway pressure (NCPAP) ventilation for CAP in this population. Method: This was a prospective multicenter study. Children who were admitted to these six centers with CAP and met the NCPAP ventilation indications, aged from 29 d to 5 years, were continuously included during November 2013 to October 2015. The baseline data were collected and NCPAP ventilation were then followed up by operation standards, and the vital signs and arterial blood gas change at special time points were observed and recorded...
May 4, 2017: Zhonghua Er Ke za Zhi. Chinese Journal of Pediatrics
https://www.readbyqxmd.com/read/28461167/singing-lessons-for-respiratory-health-a-literature-review
#20
REVIEW
Rachel B Goldenberg
OBJECTIVE: Several studies have explored the role of music and singing as a treatment for respiratory symptoms. The objective of this paper was to review the current body of literature in regard to the use of singing as both a physiological and a psychological therapy for respiratory disease and assess the role the singing teacher might play in this treatment. STUDY DESIGN: This is a literature review, discussion of results and directions for further research. METHOD: Multiple databases were searched using keywords such as "respiratory," "physiotherapy," and "pulmonary" in conjunction with "singing...
April 28, 2017: Journal of Voice: Official Journal of the Voice Foundation
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