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Deep AND Vein AND Thrombosis

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https://www.readbyqxmd.com/read/29036518/are-prothrombotic-mutations-a-time-to-event-risk-factor
#1
Branko V Tomic, Maja Z Gvozdenov, Iva B Pruner, Jelena M Simic, Mirjana K Kovac, Dragica P Radojkovic, Valentina J Djordjevic
Background: Deep vein thrombosis (DVT) represents a common disorder involving genetic and acquired risk factors. It has been proposed that acquired risk factors are more important with aging than genetic factors, indicating different prevalence of prothrombotic mutations throughout the lifespan. Objective: To determine the role of the most frequent prothrombotic genetic risk factors (Factor V [FV] Leiden and Factor II [FII] G20210A mutations) in first-time DVT etiology in patients of different ages...
September 23, 2017: Laboratory Medicine
https://www.readbyqxmd.com/read/29035980/incidence-of-symptomatic-pulmonary-embolus-and-deep-vein-thrombosis-after-knee-arthroscopy-in-the-pediatric-and-adolescent-population
#2
Brian C Lau, Jason Jagodzinski, Nirav K Pandya
OBJECTIVE: The incidence of deep venous thrombosis (DVT) and pulmonary embolism (PE) after pediatric knee arthroscopy is unknown. The purpose of this study was to determine the incidence of venous thromboembolism (VTE) after knee arthroscopy in the pediatric and adolescent population in a high-volume center. DESIGN: Retrospective cohort study. SETTING: Tertiary care children's hospital. PATIENTS: All patients who underwent arthroscopy of the knee for a sports-related injury by 2 surgeons were reviewed...
October 10, 2017: Clinical Journal of Sport Medicine: Official Journal of the Canadian Academy of Sport Medicine
https://www.readbyqxmd.com/read/29034034/pathophysiology-of-venous-thromboembolism-with-respect-to-the-anatomical-features-of-the-deep-veins-of-lower-limbs-a-review
#3
REVIEW
Ayako Ro, Norimasa Kageyama, Toshiji Mukai
Here the pathophysiology of venous thromboembolism is reviewed with respect to the anatomical features of the deep veins of lower limbs. A thrombus is less likely to form in the thigh veins compared with that in the calf veins; however, clinical symptoms are more likely to appear in the thigh veins owing to vascular occlusion. When a patient is bedridden, thrombosis is more likely to occur in the intramuscular vein, which mainly depends on muscular pumping and the venous valve, rather than in the three crural branches, which mainly depends on the pulsation of the accompanying artery...
June 25, 2017: Annals of Vascular Diseases
https://www.readbyqxmd.com/read/29033376/evolution-of-prophylaxis-protocols-for-venous-thromboembolism-in-neurosurgery-results-from-a-prospective-comparative-study-on-low-molecular-weight-heparin-elastic-stockings-and-intermittent-pneumatic-compression-devices
#4
Salvatore Chibbaro, Helene Cebula, Julien Todeschi, Marco Fricia, Doris Vigouroux, Houssem Abid, Houssen Kourbanhoussen, Raoul Pop, Beniamino Nannavecchia, Arthur Gubian, Lara Prisco, Gianfranco K I Ligarotti, Francois Proust, Mario Ganau
BACKGROUND: The incidence of venous thromboembolism (VT) in neurosurgical practice is astonishingly high representing a major cause of morbidity and mortality. Prophylaxis strategies include elastic stockings (ES), low-molecular weight heparin (LMWH) and intermittent pneumatic compression (IPC) devices. OBJECTIVE: To assess the safety and efficacy of two different VT prophylaxis protocols implemented in a European neurosurgical centre. METHODS: All patients admitted for neurosurgical intervention between 2012 and 2016 were stratified in low-, moderate- and high-risk of VT, and received a combination of ES and LMWH...
October 12, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/29032910/venous-thromboembolism-after-laparoscopic-or-robotic-biliopancreatic-diversion-with-duodenal-switch-ninety-days-outcome-of-a-10-years-experience
#5
Hamzeh M Halawani, Charis F Ripley-Hager, Mary C Naglak, Fernando Bonanni, Gintaras Antanavicius
BACKGROUND: Venous thromboembolism (VTE) is a feared complication after bariatric surgery. Biliopancreatic diversion with duodenal switch (BPD-DS) is a complex bariatric procedure that is offered typically to super morbidly obese patients. Scarce data exist in reporting VTE outcome and identifying the risk factors associated with it after BPD-DS. OBJECTIVE: To determine the risk factors for VTE after BPD-DS at 90-day follow-up. SETTING: A nonprofit regional referral center and teaching hospital in Pennsylvania...
September 9, 2017: Surgery for Obesity and related Diseases: Official Journal of the American Society for Bariatric Surgery
https://www.readbyqxmd.com/read/29032587/team-preparation-for-human-uterus-transplantation-autologous-transplantation-in-sheep-model
#6
Evgeny Solomonov, Naama Marcus Braun, Yariv Siman-Tov, Inbar Ben Shachar
We performed autologous uterus transplantation using the living-sheep donor model for team preparation before human uterine transplantation. Five sequential operations (in 3 ewes) were prospectively conducted. Surgical technique included uterus retrieval, graft preparation, and uterus transplantation. Anastomoses were performed at the level of the external iliac. At 3 weeks follow-up, the uterus and anastomoses were checked for strictures and thrombosis. Two successful auto-transplantations were made, and one failed because of undeveloped uterine arteries (< 1 mm in diameter)...
October 15, 2017: Clinical Transplantation
https://www.readbyqxmd.com/read/29030060/bedside-diagnosis-of-deep-vein-thrombosis-using-pocket-sized-ultrasound
#7
Elizabeth Baker, Michael Wagner
No abstract text is available yet for this article.
October 10, 2017: American Journal of Medicine
https://www.readbyqxmd.com/read/29029715/the-role-of-inferior-vena-cava-filters-in-pulmonary-embolism
#8
Jonathan D Steinberger, Scott J Genshaft
Pulmonary embolism (PE) is a cause of significant morbidity and mortality, with an estimated 600,000 cases of clinically significant PE in the United States annually, and roughly 200,000 deaths per annum directly attributable to PE. By far the most frequent cause of PE is deep vein thrombosis originating in the lower extremities, which travels to the pulmonary vasculature. The mainstay of treatment is anticoagulation, but multiple additional treatments exist for patients in whom anticoagulation is inadequate or contraindicated...
September 2017: Techniques in Vascular and Interventional Radiology
https://www.readbyqxmd.com/read/29029707/epidemiology-pathophysiology-stratification-and-natural-history-of-pulmonary-embolism
#9
Nicholas J Giordano, Paul S Jansson, Michael N Young, Kaitlin A Hagan, Christopher Kabrhel
Pulmonary embolism (PE) is a common and potentially fatal form of venous thromboembolism that can be challenging to diagnose and manage. PE occurs when there is obstruction of the pulmonary vasculature and is a common cause of morbidity and mortality in the United States. A combination of acquired and inherited factors may contribute to the development of this disease and should be considered, since they have implications for both susceptibility to PE and treatment. Patients with suspected PE should be evaluated efficiently to diagnose and administer therapy as soon as possible, but the presentation of PE is variable and nonspecific so diagnosis is challenging...
September 2017: Techniques in Vascular and Interventional Radiology
https://www.readbyqxmd.com/read/29029334/effect-of-long-term-hydroxychloroquine-on-vascular-events-in-patients-with-systemic-lupus-erythematosus-a-database-prospective-cohort-study
#10
Chung-Yuan Hsu, Yu-Sheng Lin, Yu-Jih Su, Hsing-Fen Lin, Ming-Shyan Lin, Ya-Jhu Syu, Tien-Tsai Cheng, Shan-Fu Yu, Jia-Feng Chen, Tien-Hsing Chen
Objectives: The incidence of thromboembolism in patients with SLE is higher than that in the general population. HCQ, widely used to treat lupus, may have vascular protective effects. The aim of this study was to determine whether long-term HCQ exposure is associated with decreased thromboembolism risk in SLE. Methods: We designed a prospective cohort study within an SLE population based on the National Health Insurance Research Database in Taiwan. We divided participants into HCQ and control groups according to HCQ prescription during the first year...
September 27, 2017: Rheumatology
https://www.readbyqxmd.com/read/29027356/relationship-between-neighbourhood-socioeconomic-status-and-venous-thromboembolism-results-from-a-population-based-study
#11
D Kort, N van Rein, F J M van der Meer, H W Vermaas, N Wiersma, S C Cannegieter, W M Lijfering
BACKGROUND: The association between socioeconomic status and arterial cardiovascular disease is well established. However, despite its high burden of disability-adjusted life years, little research has been done to determine whether socioeconomic status is associated with venous thromboembolism. OBJECTIVE: To determine if neighbourhood socioeconomic status is associated with venous thromboembolism in a population-based study from the Netherlands. METHODS: We identified all patients aged 15 years and older with a first event of venous thromboembolism from inhabitants who lived in the urban districts of The Hague, Leiden and Utrecht in the Netherlands in 2008-2012...
October 12, 2017: Journal of Thrombosis and Haemostasis: JTH
https://www.readbyqxmd.com/read/29026346/treatment-with-direct-oral-anticoagulants-in-patients-with-upper-extremity-deep-vein-thrombosis
#12
Francisco Sánchez Montiel, Raein Ghazvinian, Anders Gottsäter, Johan Elf
BACKGROUND: Upper extremity deep vein thrombosis (UEDVT) constitutes around 10% of all DVT, and can cause both pulmonary embolism (PE) and postthrombotic syndrome (PTS) in the arm. The incidence of secondary UEDVT is increasing due to widespread use of central venous catheters in patients with cancer and other chronic diseases. The safety and efficacy of using new direct acting oral anti coagulants (DOAC) in the treatment of UEDVT has not been systematically evaluated. Our aims were to evaulate efficacy, safety, and risk of recurrence of venous thromboembolism (VTE) during DOAC treatment in UEDVT patients...
2017: Thrombosis Journal
https://www.readbyqxmd.com/read/29022529/deep-vein-thrombosis-in-the-era-of-high-hiv-and-tuberculosis-prevalence-a-prospective-review-of-its-diagnosis-and-treatment-in-a-quaternary-centre
#13
K E Hodkinson, J N Mahlangu
BACKGROUND: Venous thromboembolic disease (VTE) is a leading cause of morbidity and mortality worldwide. HIV and tuberculosis (TB) infections have an aetiological association with VTE. Implementation of national HIV and TB programmes in South Africa (SA) has changed the burden of these two conditions, with resultant effects on VTE prevalence. Furthermore, with the increased use of direct oral anticoagulants (DOACs), baseline thrombosis data are needed to evaluate the effect of these new agents...
September 22, 2017: South African Medical Journal, Suid-Afrikaanse Tydskrif Vir Geneeskunde
https://www.readbyqxmd.com/read/29020303/risk-of-venous-thromboembolism-following-hemorrhagic-fever-with-renal-syndrome-a-self-controlled-case-series-study
#14
Anne-Marie Connolly-Andersen, Heather Whitaker, Jonas Klingström, Clas Ahlm
Background: Bleeding is associated with viral hemorrhagic fevers; however, thromboembolic complications has received less attention. Hemorrhagic fever with renal syndrome (HFRS) is a mild viral hemorrhagic fever caused by Puumala hantavirus. We previously identified HFRS as a risk factor for myocardial infarction and stroke, but the risk for venous thromboembolism (VTE), including deep vein thrombosis (DVT) and pulmonary embolism (PE) is unknown. Methods: Personal identity numbers from the Swedish HFRS database were cross-linked with the Patient Register to obtain information on all causes for hospitalization during 1964 to 2013...
September 4, 2017: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
https://www.readbyqxmd.com/read/29019812/venous-thromboembolism-after-adult-lung-transplantation-a-frequent-event-associated-with-lower-survival
#15
Manuel L Ribeiro Neto, Marie Budev, Daniel A Culver, C Randall Lane, Marcelo Gomes, Xiao-Feng Wang, Paulo Novis Rocha, Mitchell A Olman
BACKGROUND: The incidence of venous thromboembolism (VTE) after lung transplantation (LTX) varies significantly across studies. Two studies have suggested that these thrombotic events are associated with a lower posttransplant survival. Herein, we sought to determine the incidence, predictors and impact of VTE on survival after LTX at a quaternary referral center. METHODS: This was a large cohort study of LTX recipients. Key outcome parameters were time to VTE after transplant and survival...
October 10, 2017: Transplantation
https://www.readbyqxmd.com/read/29017137/ovarian-vein-thrombosis-after-total-laparoscopic-hysterectomy-with-unilateral-adnexectomy-a-case-report
#16
Samer Nikolaos Al-Αchmar, Sofoklis Stavrou, Athanasios Protopapas, Peter Drakakis, Panagiota Siemou, Ioannis Chatzipapas
INTRODUCTION: Ovarian vein thrombosis is a rare but potentially serious complication after surgical and gynecologic procedures such as oophorectomy and hysterectomy. The association of this event with laparoscopic hysterectomy in particular, is very rare. Only two cases have been described so far. PRESENTATION OF CASE: We present a case of ovarian vein thrombosis after laparoscopic hysterectomy in a 40-year-old with deep endometriosis and multiple intramural uterine myomas...
October 4, 2017: International Journal of Surgery Case Reports
https://www.readbyqxmd.com/read/29016487/ovarian-vein-thrombosis-incidence-of-recurrent-venous-thromboembolism-and-survival
#17
Charles J Lenz, Waldemar E Wysokinski, Stanislav Henkin, Kevin P Cohoon, Ana Casanegra, Benjamin S Simmons, Rayya A Saadiq, Paul R Daniels, Ewa M Wysokinska, Haraldur Bjarnason, Robert D McBane
OBJECTIVE: To identify the risk of venous thromboembolism recurrence, major bleeding, and mortality in patients with ovarian vein thrombosis so as to better define optimal treatment strategies. METHODS: Patients with ovarian vein thrombosis (1990-2015) and age- and gender-matched patients with contemporary leg deep vein thrombosis (DVT) were assessed for differences in etiology, venous thromboembolism recurrence, and survival in a case-control study. RESULTS: Over the timeframe of this study, only 219 ovarian vein thrombosis cases were identified compared with 13,417 leg DVTs...
October 6, 2017: Obstetrics and Gynecology
https://www.readbyqxmd.com/read/28994575/thrombin-activatable-microbubbles-as-potential-ultrasound-contrast-agents-for-the-detection-of-acute-thrombosis
#18
Jacques Lux, Alexander M Vezeridis, Kenneth Hoyt, Stephen Roy Adams, Amanda M Armstrong, Shashank R Sirsi, Robert Mattrey
Acute deep vein thrombosis (DVT) is the formation of a blood clot in the deep veins of the body that can lead to fatal pulmonary embolism. Acute DVT is difficult to distinguish from chronic DVT by ultrasound (US), the imaging modality of choice, and is therefore treated aggressively with anticoagulants, which can lead to internal bleeding. Here we demonstrate that conjugating perfluorobutane (PFB)-filled microbubbles (MBs) with thrombin-sensitive activatable cell-penetrating peptides (ACPP) could lead to the development of contrast agents that detect acute thrombosis with US imaging...
October 10, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/28993088/hip-and-knee-arthroplasty-orthopedic-literature-in-medical-journals-is-it-negatively-biased
#19
Ronald E Delanois, Chukwuweike U Gwam, Nicolas S Piuzzi, Morad Chughtai, Arthur L Malkani, Peter M Bonutti, Michael A Mont
BACKGROUND: Healthcare policy is often determined by well-designed studies most often published in high-impact medical journals. However, concern about the presence of publication bias against lower-extremity arthroplasty-related studies has called into question some of the validity of certain reports. There are only a few studies investigating the presence of the bias in high-impact medical journals against lower-extremity arthroplasty intervention, particularly in the Journal of American Medical Association (JAMA), New England Journal of Medicine (NEJM), and the Lancet...
September 19, 2017: Journal of Arthroplasty
https://www.readbyqxmd.com/read/28993079/lateral-femoral-epicondylar-osteotomy-for-correction-of-fixed-valgus-deformity-in-total-knee-arthroplasty-a-technical-note
#20
Jacob M Conjeski, Giles R Scuderi
BACKGROUND: Multiple surgical techniques exist to restore limb alignment and to balance soft tissues in valgus knees during total knee arthroplasty (TKA). One technique is to perform a lateral femoral epicondylar osteotomy. METHODS: A retrospective analysis was performed on all patients with a fixed valgus deformity that was corrected with a lateral femoral epicondylar osteotomy during TKA. Preoperative and postoperative Knee Society Knee Scores, knee stability, range of motion, and radiographic alignment were recorded...
September 19, 2017: Journal of Arthroplasty
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