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Impotence prostate cancer mri

P Pepe, M Pennisi
Erectile dysfunction (ED) following transperineal prostate biopsy (TPB) was prospectively evaluated. From January 2011 to January 2014, 1050 patients were submitted to TPB: 18 core (extended TPB) in 610 cases, 28 core (saturation TPB) in 360 cases and 32 core (saturation plus magnetic resonance imaging (MRI) targeted TPB) in 210 cases. The indications for biopsy were increasing prostate-specific antigen (PSA) or PSA>10 ng ml(-1). All patients were prospectively evaluated with the 5-item version of the International Index of Erectile Function (IIEF-5) at time zero and at 1, 3 and 6 months from TPB...
January 2016: International Journal of Impotence Research
David A Woodrum, Akira Kawashima, R Jeffrey Karnes, Brian J Davis, Igor Frank, Donald E Engen, Krzysztof R Gorny, Joel P Felmlee, Matthew R Callstrom, Lance A Mynderse
OBJECTIVE: To establish the feasibility of magnetic resonance imaging (MRI)-guided cryoablation in patients with previous radical prostatectomy and MRI visualized biopsy-proven local recurrence of prostate adenocarcinoma. MATERIALS AND METHODS: Eighteen postprostatectomy patients (mean 67, 57-78 years) were treated with MRI-guided cryoablation for recurrent prostate carcinoma. Patients were found to have a hyperenhancing nodule using multiparametric MRI with endorectal coil followed by a positive transrectal ultrasound-guided biopsy...
October 2013: Urology
B Nicolas Bloch, Robert E Lenkinski, Neil M Rofsky
Management decisions for patients with prostate cancer present a dilemma for both patients and their clinicians because prostate cancers demonstrate a wide range in biologic activity, with the majority of cases not leading to a prostate cancer related death. Furthermore, the current treatment options have significant side effects, such as incontinence, rectal injury and impotence. Key elements for guiding appropriate treatment include: distinction of organ-confined disease from extracapsular extension (ECE); and determination of tumor volume and tumor grade, none of which have been satisfactorily accomplished in today's pre-treatment paradigm...
2008: Cancer Biomarkers: Section A of Disease Markers
Patrick W McLaughlin, Vrinda Narayana, Amichay Meirovitz, Amichay Meriowitz, Sara Troyer, Peter L Roberson, Roger Gonda, Howard Sandler, Lon Marsh, Theodore Lawrence, Marc Kessler
PURPOSE: Most evidence suggests that impotence after prostate radiation therapy has a vascular etiology. The corpus cavernosum (CC) and the internal pudendal artery (IPA) are the critical vascular structures related to erectile function. This study suggests that it is feasible to markedly decrease radiation dose to the CC and the IPA and directly determine the impact of dose limitation on potency. METHODS AND MATERIALS: Twenty-five patients (10 external beam, 15 brachytherapy) underwent MRI/CT-based treatment planning for prostate cancer...
January 1, 2005: International Journal of Radiation Oncology, Biology, Physics
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