Jethro C C Kwong, Adree Khondker, Eric Meng, Nicholas Taylor, Cynthia Kuk, Nathan Perlis, Girish S Kulkarni, Robert J Hamilton, Neil E Fleshner, Antonio Finelli, Theodorus H van der Kwast, Amna Ali, Munir Jamal, Frank Papanikolaou, Thomas Short, John R Srigley, Valentin Colinet, Alexandre Peltier, Romain Diamand, Yolene Lefebvre, Qusay Mandoorah, Rafael Sanchez-Salas, Petr Macek, Xavier Cathelineau, Martin Eklund, Alistair E W Johnson, Andrew Feifer, Alexandre R Zlotta
BACKGROUND: Accurate prediction of side-specific extraprostatic extension (ssEPE) is essential for performing nerve-sparing surgery to mitigate treatment-related side-effects such as impotence and incontinence in patients with localised prostate cancer. Artificial intelligence (AI) might provide robust and personalised ssEPE predictions to better inform nerve-sparing strategy during radical prostatectomy. We aimed to develop, externally validate, and perform an algorithmic audit of an AI-based Side-specific Extra-Prostatic Extension Risk Assessment tool (SEPERA)...
July 2023: The Lancet. Digital health