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Fever and virus in childrens

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https://www.readbyqxmd.com/read/29895163/evidence-of-hepatitis-a-virus-infection-in-the-patients-with-acute-encephalitis-syndrome-in-gorakhpur-region-north-india
#1
M S Joshi, B V Tandale, M M Gore, S Bhalla, Y K Gurav, G N Sapkal, K P Kushwaha A, S D Chitambar
The etiological agent remained unidentified in a large number of patients hospitalized for acute encephalitis syndrome (AES) in 2008-2009 in Uttar Pradesh and Bihar, north India. All patients were found to present with fever and altered sensorium, while 28%, 19% and 13% showed hepatomegaly, splenomegaly and meningeal signs, respectively. Involvement mostly of children with abnormal hepatic features prompted us to undertake an exploratory study on viral hepatitis A to determine its association, if any, with hepatic derangements...
2018: Acta Virologica
https://www.readbyqxmd.com/read/29894797/diagnosis-and-outcomes-of-pregnant-women-with-zika-virus-infection-in-two-municipalities-of-risaralda-colombia-second-report-of-the-zikerncol-study
#2
Alfonso J Rodriguez-Morales, Jaime A Cardona-Ospina, Valeria Ramirez-Jaramillo, Javier A Gaviria, Gloria María González-Moreno, Juan D Castrillón-Spitia, Alejandra López-Villegas, Estefania Morales-Jiménez, Valentina Ramírez-Zapata, German Eduardo Rueda-Merchán, Adriana M Trujillo, Fredy A Tabares-Villa, Valentina Henao-SanMartin, David R Murillo-Garcia, Johana Andrea Herrera-Soto, Marta Liliana Buitrago-Cañas, Matthew H Collins, Juan Carlos Sepúlveda-Arias, José J Londoño, Héctor D Bedoya-Rendón, Javier de Jesús Cárdenas-Pérez, Sandra X Olaya, Guillermo J Lagos-Grisales
BACKGROUND: Zika virus (ZIKV) infection has emerged as a significant threat for pregnant women and newborns in populations living in or visiting Latin America. We previously reported a preliminary analysis in Sucre, Colombia, as the first group of pregnant women with RT-PCR-confirmed ZIKV (ZIKa enEmbarazadas yReciénNacidos enCOLombia, ZIKERNCOL). METHODS: In this second report, findings of the first 86 pregnant women from La Virginia and Dosquebradas (municipalities), Risaralda, Colombia, with RT-PCR-confirmed ZIKV infection are reported...
June 9, 2018: Travel Medicine and Infectious Disease
https://www.readbyqxmd.com/read/29889810/pathogen-clearance-and-new-respiratory-tract-infections-among-febrile-children-in-zanzibar-investigated-with-multitargeting-real-time-polymerase-chain-reaction-on-paired-nasopharyngeal-swab-samples
#3
Kristina Elfving, Deler Shakely, Maria Andersson, Kimberly Baltzell, Mwinyi I Msellem, Anders Björkman, Andreas Mårtensson, Max Petzold, Birger Trollfors, Magnus Lindh
BACKGROUND: New molecular methods have revealed frequent and often polymicrobial respiratory infections in children in low-income settings. It is not known whether presence of multiple pathogens is due to prolonged infections or to frequent exposure. The aim of this study was to analyze short-term pathogen clearance from nasopharynx and the rate of new respiratory tract infections in febrile preschool children. METHODS: Children (n = 207) with uncomplicated acute febrile illness 2-59 months of age presenting to a health center in Zanzibar, Tanzania, April-July 2011, were included...
July 2018: Pediatric Infectious Disease Journal
https://www.readbyqxmd.com/read/29873412/an-outbreak-due-to-mumps-virus-genotype-g-in-a-tribal-population-during-2016-17-from-india
#4
Sunil R Vaidya, Siddharth M Tilavat, Venkat S Hamde, Divya R Bhattad
Patients with fever and uni or bilateral parotitis were observed in a tribal population of Galonda and Silli villages (Dadra and Nagar Haveli, India) between 2nd October 2016 and 19th March 2017. Consequently, investigation was performed to determine the magnitude and epidemiological characteristics of the outbreak. Overall, 139 suspected mumps cases were reported from both villages. Majority of the suspected cases were 5-15 years old, except three adults without any noticeable complications among reported cases...
June 6, 2018: Microbiology and Immunology
https://www.readbyqxmd.com/read/29868136/prevalence-of-family-history-of-autoimmune-disorders-in-juvenile-systemic-lupus-erythematosus
#5
Parisa Ashournia, Payman Sadeghi, Nima Rezaei, Mohammad-Hassan Moradinejad, Vahid Ziaee
One of the causes of infants' hospitalizations is bronchiolitis, while different viral agents could be causative agents. As there is little information regarding the common agents of bronchiolitis in Iranian infants, we designed this study to determine which agents were responsible for hospitalization due to bronchiolitis among infants in an Iranian tertiary center. Two hundred and three infants with bronchiolitis who were hospitalized in Bahrami hospital were enrolled. Data regarding age, sex, duration of hospitalization, exposure to smoking, previous antibiotic usage and fever were collected for all enrolled cases...
March 2018: Mædica
https://www.readbyqxmd.com/read/29868135/viral-aetiology-of-bronchiolitis-in-hospitalised-children-in-a-tertiary-center-in-tehran
#6
Ali Akbar Rahbarimanesh, Anahita Izadi, Mahsa Ghajarzadeh
One of the causes of infants' hospitalizations is bronchiolitis, while different viral agents could be causative agents. As there is little information regarding the common agents of bronchiolitis in Iranian infants, we designed this study to determine which agents were responsible for hospitalization due to bronchiolitis among infants in an Iranian tertiary center. Two hundred and three infants with bronchiolitis who were hospitalized in Bahrami hospital were enrolled. Data regarding age, sex, duration of hospitalization, exposure to smoking, previous antibiotic usage and fever were collected for all enrolled cases...
March 2018: Mædica
https://www.readbyqxmd.com/read/29851952/detection-and-phylogenetic-characterization-of-arbovirus-dual-infections-among-persons-during-a-chikungunya-fever-outbreak-haiti-2014
#7
Sarah K White, Carla Mavian, Maha A Elbadry, Valery Madsen Beau De Rochars, Taylor Paisie, Taina Telisma, Marco Salemi, John A Lednicky, J Glenn Morris
In the context of recent arbovirus epidemics, questions about the frequency of simultaneous infection of patients with different arbovirus species have been raised. In 2014, a major Chikungunya virus (CHIKV) epidemic impacted the Caribbean and South America. As part of ongoing screening of schoolchildren presenting with acute undifferentiated febrile illness in rural Haiti, we used RT-PCR to identify CHIKV infections in 82 of 100 children with this diagnosis during May-August 2014. Among these, eight were infected with a second arbovirus: six with Zika virus (ZIKV), one with Dengue virus serotype 2, and one with Mayaro virus (MAYV)...
May 31, 2018: PLoS Neglected Tropical Diseases
https://www.readbyqxmd.com/read/29851943/progress-toward-rubella-and-congenital-rubella-syndrome-control-south-east-asia-region-2000-2016
#8
Sudhir Khanal, Sunil Bahl, Mohammad Sharifuzzaman, Deepak Dhongde, Sirima Pattamadilok, Susan Reef, Michelle Morales, Alya Dabbagh, Katrina Kretsinger, Minal Patel
In 2013, the 66th session of the Regional Committee of the World Health Organization (WHO) South-East Asia Region (SEAR)* adopted the goal of elimination of measles and control† of rubella and congenital rubella syndrome (CRS) by 2020 (1). Rubella is the leading vaccine-preventable cause of birth defects. Although rubella typically causes a mild fever and rash in children and adults, rubella virus infection during pregnancy, especially during the first trimester, can result in miscarriage, fetal death, or a constellation of congenital malformations known as CRS, commonly including visual, auditory, and/or cardiac defects, and developmental delay (2)...
June 1, 2018: MMWR. Morbidity and Mortality Weekly Report
https://www.readbyqxmd.com/read/29850402/empirical-treatment-with-parenteral-acyclovir-in-a-child-with-herpes-simplex-virus-hepatitis-and-acute-lymphoblastic-leukemia
#9
Nesreen A Faqih, Mahmoud A Alfaqih, Khadra Salami, Brian Herron, Iyad Sultan, Maysa Al-Hussaini
Introduction: Hepatitis secondary to Herpes Simplex Virus (HSV) infection is a complication that often leads to fatal hepatic failure. Early treatment with the anti-viral drug, acyclovir, is life-saving. In view of the non-specific nature of the signs and symptoms associated with HSV hepatitis, diagnosis is often made late during the course of the disease; a factor that largely contributes to the high mortality rate of this treatable disease complication. There is thus a growing consensus in the field to initiate empirical treatment with acyclovir once suspicion of HSV hepatitis is raised even before reaching a conclusive diagnosis...
2018: IDCases
https://www.readbyqxmd.com/read/29845955/hand-foot-and-mouth-disease-in-the-andaman-islands-india
#10
Surya Palani, Muruganandam Nagarajan, Ashok Kumar Biswas, Rajesh Reesu, Vijayachari Paluru
OBJECTIVE: To investigate an outbreak of Hand, foot and mouth disease (HFMD) in Andaman Islands during 2013. METHODS: Epidemiological, clinical data and samples were collected from HFMD patients who attended selected hospitals. Data were analyzed and samples were processed for detection of Enterovirus and further confirmed by sequencing. Serotype-specific molecular typing was also done to identify the etiological agent. RESULTS: Of the 246 suspected patients, most were affected in August 2013 (92/246, 37...
May 15, 2018: Indian Pediatrics
https://www.readbyqxmd.com/read/29813148/symptomatic-zika-virus-infection-in-infants-children-and-adolescents-living-in-puerto-rico
#11
Jennifer S Read, Brenda Torres-Velasquez, Olga Lorenzi, Aidsa Rivera Sanchez, Sanet Torres-Torres, Lillian V Rivera, Sheila M Capre-Franceschi, Carlos Garcia-Gubern, Jorge Munoz-Jordan, Gilberto A Santiago, Luisa I Alvarado
Importance: Little information is available regarding Zika virus (ZIKV) infection in children. Objective: To describe patients younger than 18 years who were infected with ZIKV and were enrolled in the Sentinel Enhanced Dengue and Acute Febrile Illness Surveillance System (SEDSS). Design, Setting, and Participants: Children infected with ZIKV with 7 or fewer days of fever or emancipated minors aged 14 to 17 years with a generalized maculopapular rash, arthritis or arthralgia, or nonpurulent conjunctivitis were eligible for enrollment on or before December 31, 2016, in Puerto Rico...
May 29, 2018: JAMA Pediatrics
https://www.readbyqxmd.com/read/29789000/spontaneous-splenic-rupture-complicating-primary-varicella-zoster-infection-a-case-report
#12
Aarthy Uthayakumar, David Harrington
BACKGROUND: Primary varicella zoster virus (VZV) infection is a common illness, predominantly affecting children. Its course is typically benign, although severe complications have been described. Splenic rupture is an extremely rare and potentially fatal complication of primary VZV infection, with only a handful of cases reported in the literature. CASE PRESENTATION: A 32-year-old Romanian man with no significant past medical history, presented with a 2 day history of sudden onset, worsening generalised abdominal pain and a 1 day history of vomiting...
May 22, 2018: BMC Research Notes
https://www.readbyqxmd.com/read/29780032/severe-outcomes-associated-with-respiratory-viruses-in-newborns-and-infants-a-prospective-viral-surveillance-study-in-jordan
#13
Najwa Khuri-Bulos, Lindsey Lawrence, Bhinnata Piya, Li Wang, Christopher Fonnesbeck, Samir Faouri, Asem Shehabi, Sten H Vermund, John V Williams, Natasha B Halasa
OBJECTIVE: To assess virus-specific hospitalisation rates, risk factors for illness severity and seasonal trends in children hospitalised with acute respiratory infections (ARI). DESIGN: Prospective cohort study. SETTING: A government hospital serving low-income and middle-income population in Amman, Jordan. PARTICIPANTS: Children under 2 years of age hospitalised with fever and/or respiratory symptoms (n=3168) from 16 March 2010 to 31 March 2013...
May 20, 2018: BMJ Open
https://www.readbyqxmd.com/read/29769256/early-use-of-antibiotics-for-at-risk-children-with-influenza-archie-protocol-for-a-double-blind-randomised-placebo-controlled-trial
#14
Kay Wang, Tricia Carver, Sharon Tonner, Malcolm G Semple, Alastair D Hay, Michael Moore, Paul Little, Christopher Butler, Andrew Farmer, Rafael Perera, Ly-Mee Yu, Susan Mallett, Jane Wolstenholme, Anthony Harnden
INTRODUCTION: Influenza and influenza-like illness (ILI) create considerable burden on healthcare resources each winter. Children with pre-existing conditions such as asthma, diabetes mellitus and cerebral palsy are among those at greatest risk of clinical deterioration from influenza/ILI. The Antibiotics for at Risk CHildren with InfluEnza (ARCHIE) trial aims to determine whether early oral treatment with the antibiotic co-amoxiclav reduces the likelihood of reconsultation due to clinical deterioration in these 'at risk' children...
May 16, 2018: BMJ Open
https://www.readbyqxmd.com/read/29751747/a-fatal-case-associated-with-respiratory-syncytial-virus-infection-in-a-young-child
#15
Lili Xu, Hengmiao Gao, Jiansheng Zeng, Jun Liu, Cong Lu, Xiaolei Guan, Suyun Qian, Zhengde Xie
BACKGROUND: Respiratory syncytial virus (RSV) is the most common viral cause of pediatric bronchiolitis and pneumonia worldwide. Risk factors for high mortality and prolonged morbidity after RSV infection include premature birth, bronchopulmonary dysplasia, congenital heart disease, and Down syndrome. However, some previously healthy, full-term children who are infected with RSV also require hospitalization and even experience severe sequelae or death. CASE PRESENTATION: In this report, we present the case of an RSV-associated death of a child who was born at full-term and developed normally up to the age of 2 years old...
May 11, 2018: BMC Infectious Diseases
https://www.readbyqxmd.com/read/29741717/influenza-associated-acute-necrotizing-encephalopathy-in-siblings
#16
Ashley Howard, Timothy M Uyeki, Jaime Fergie
Encephalopathy is an important complication associated with influenza, most frequently observed in young children, with a wide range of severity. The most severe category of influenza-associated encephalopathy (IAE) is acute necrotizing encephalopathy (ANE), characterized by high frequency of neurologic sequelae and fatal outcomes. We report two young siblings who developed fever and seizures with altered mental status. Influenza A(H1N1)pdm09 virus infection was identified in upper respiratory tract specimens from both patients, and neuroimaging revealed bilateral inflammatory lesions, consistent with acute necrotizing encephalopathy...
May 4, 2018: Journal of the Pediatric Infectious Diseases Society
https://www.readbyqxmd.com/read/29713613/acute-gastritis-and-splenic-infarction-caused-by-epstein-barr-virus
#17
Ji Eun Jeong, Kyung Moon Kim, Hye Lim Jung, Jae Won Shim, Deok Soo Kim, Jung Yeon Shim, Moon Soo Park, Soo Kyung Park
Epstein-Barr virus (EBV) infection can be presented with various clinical manifestations and different levels of severity when infected. Infectious mononucleosis, which is most commonly caused by EBV infection in children and adolescents, is a clinical syndrome characterized by fatigue, malaise, fever, sore throat, and generalized lymphadenopathy. But rarely, patients with infectious mononucleosis may present with gastrointestinal symptoms and complicated by gastritis, splenic infarction, and splenic rupture...
April 2018: Pediatric Gastroenterology, Hepatology & Nutrition
https://www.readbyqxmd.com/read/29707592/varicella-pneumonia-case-report-and-review-of-a-potentially-lethal-complication-of-a-common-disease
#18
John T Denny, Zoe M Rocke, Valerie A McRae, Julia E Denny, Christine Hunter Fratzola, Sajjad Ibrar, Joyce Bonitz, James T Tse, Shaul Cohen, Scott J Mellender, Geza K Kiss
Varicella zoster virus causes varicella (chickenpox). It can be reactivated endogenously many years later to cause herpes zoster (shingles). Although varicella is usually a benign disease in healthy children, it resulted in over 11 000 hospitalizations and over 100 deaths every year, in all ages, in the United States. Morbidity was considerably worse in older teenagers and adults. Between 5% and 15% of cases of adult chickenpox will produce some form of pulmonary illness. Progression to pneumonia risk factors include pregnancy, age, smoking, chronic obstructive pulmonary disease, and immunosuppression...
January 2018: Journal of Investigative Medicine High Impact Case Reports
https://www.readbyqxmd.com/read/29698505/estimation-of-community-level-influenza-associated-illness-in-a-low-resource-rural-setting-in-india
#19
Siddhartha Saha, Vivek Gupta, Fatimah S Dawood, Shobha Broor, Kathryn E Lafond, Mandeep S Chadha, Sanjay K Rai, Anand Krishnan
OBJECTIVE: To estimate rates of community-level influenza-like-illness (ILI) and influenza-associated ILI in rural north India. METHODS: During 2011, we conducted household-based healthcare utilization surveys (HUS) for any acute medical illness (AMI) in preceding 14days among residents of 28villages of Ballabgarh, in north India. Concurrently, we conducted clinic-based surveillance (CBS) in the area for AMI episodes with illness onset ≤3days and collected nasal and throat swabs for influenza virus testing using real-time polymerase chain reaction...
2018: PloS One
https://www.readbyqxmd.com/read/29698412/clinical-manifestations-in-infants-and-children-with-mycoplasma-pneumoniae-infection
#20
Mia Johanna Søndergaard, Martin Barfred Friis, Dennis Schrøder Hansen, Inger Merete Jørgensen
BACKGROUND: Mycoplasma pneumoniae is a common cause of community-acquired pneumonia in older children. Pulmonary and extra-pulmonary symptoms associated with M. pneumoniae infection are reported. M. pneumoniae is mainly epidemic in Denmark with the recurrence every 4-7th year. AIMS: Retrospectively, to describe the epidemiology and clinical features, in infants and children, during the M. pneumoniae epidemic in 2010 and 2011. METHODS: All children under the age of 16 that were tested for M...
2018: PloS One
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