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https://www.readbyqxmd.com/read/28521909/proximal-interphalangeal-joint-ankylosis-in-an-early-medieval-horse-from-wroc%C3%A5-aw-cathedral-island-poland
#1
Maciej Janeczek, Aleksander Chrószcz, Vedat Onar, Radomir Henklewski, Aleksandra Skalec
Animal remains that are unearthed during archaeological excavations often provide useful information about socio-cultural context, including human habits, beliefs, and ancestral relationships. In this report, we present pathologically altered equine first and second phalanges from an 11th century specimen that was excavated at Wrocław Cathedral Island, Poland. The results of gross examination, radiography, and computed tomography, indicate osteoarthritis of the proximal interphalangeal joint, with partial ankylosis...
June 2017: International Journal of Paleopathology
https://www.readbyqxmd.com/read/28484253/human-ancestry-correlates-with-language-and-reveals-that-race-is-not-an-objective-genomic-classifier
#2
Jennifer L Baker, Charles N Rotimi, Daniel Shriner
Genetic and archaeological studies have established a sub-Saharan African origin for anatomically modern humans with subsequent migrations out of Africa. Using the largest multi-locus data set known to date, we investigated genetic differentiation of early modern humans, human admixture and migration events, and relationships among ancestries and language groups. We compiled publicly available genome-wide genotype data on 5,966 individuals from 282 global samples, representing 30 primary language families. The best evidence supports 21 ancestries that delineate genetic structure of present-day human populations...
May 8, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28391047/evolution-of-photoperiod-sensing-in-plants-and-algae
#3
REVIEW
Gloria Serrano-Bueno, Francisco J Romero-Campero, Eva Lucas-Reina, Jose M Romero, Federico Valverde
Measuring day length confers a strong fitness improvement to photosynthetic organisms as it allows them to anticipate light phases and take the best decisions preceding diurnal transitions. In close association with signals from the circadian clock and the photoreceptors, photoperiodic sensing constitutes also a precise way to determine the passing of the seasons and to take annual decisions such as the best time to flower or the beginning of dormancy. Photoperiodic sensing in photosynthetic organisms is ancient and two major stages in its evolution could be identified, the cyanobacterial time sensing and the evolutionary tool kit that arose in green algae and developed into the photoperiodic system of modern plants...
April 6, 2017: Current Opinion in Plant Biology
https://www.readbyqxmd.com/read/28381901/an-ethnolinguistic-and-genetic-perspective-on-the-origins-of-the-dravidian-speaking-brahui-in-pakistan
#4
Luca Pagani, Vincenza Colonna, Chris Tyler-Smith, Qasim Ayub
Pakistan is a part of South Asia that modern humans encountered soon after they left Africa ~50 - 70,000 years ago. Approximately 9,000 years ago they began establishing cities that eventually expanded to represent the Harappan culture, rivalling the early city states of Mesopotamia. The modern state constitutes the north western land mass of the Indian sub-continent and is now the abode of almost 200 million humans representing many ethnicities and linguistic groups. Studies utilising autosomal, Y chromosomal and mitochondrial DNA markers in selected Pakistani populations revealed a mixture of Western Eurasian-, South- and East Asian-specific lineages, some of which were unequivocally associated with past migrations...
2017: Man in India
https://www.readbyqxmd.com/read/28332253/sex-and-ancestry-determine-the-free-running-circadian-period
#5
Charmane I Eastman, Victoria A Tomaka, Stephanie J Crowley
The endogenous, free-running circadian period (τ) determines the phase relationship that an organism assumes when entrained to the 24-h day. We found a shorter circadian period in African Americans compared to non-Hispanic European Americans (24.07 versus 24.33 h). We speculate that a short circadian period, closer to 24 h, was advantageous to humans living around the equator, but when humans migrated North out of Africa, where the photoperiod changes with seasons, natural selection favoured people with longer circadian periods...
March 23, 2017: Journal of Sleep Research
https://www.readbyqxmd.com/read/28328951/practising-pastoralism-in-an-agricultural-environment-an-isotopic-analysis-of-the-impact-of-the-hunnic-incursions-on-pannonian-populations
#6
Susanne E Hakenbeck, Jane Evans, Hazel Chapman, Erzsébet Fóthi
We conducted a multi-isotope study of five fifth-century AD cemeteries in modern-day Hungary to determine relationships between nomadic-pastoralist incomers-the historically documented Huns and other nomadic groups-and the sedentary agricultural population of the late Roman province of Pannonia. Contemporary historical sources describe this relationship as adversarial and destructive for the late Roman population, but archaeological evidence indicates high levels of hybridity between different groups. We undertook carbon, nitrogen, strontium and oxygen isotope analyses of bone collagen, dentine and tooth enamel at Keszthely-Fenékpuszta, Hács-Béndekpuszta, Győr-Széchenyi Square, Mözs and Szolnok-Szanda to examine these relationships through past subsistence practices...
2017: PloS One
https://www.readbyqxmd.com/read/28283140/pay-matters-the-piece-rate-and-health-in-the-developing-world
#7
Mary E Davis
BACKGROUND: Piece rate pay remains a common form of compensation in developing-world industries. While the piece rate may boost productivity, it has been shown to have unintended consequences for occupational safety and health, including increased accident and injury risk. OBJECTIVES: This paper explores the relationship between worker pay and physical and emotional health, and questions the modern day business case for piece rate pay in the developing world. METHODS: The relationship between piece rate and self-reported measures of physical and emotional health is estimated using a large survey of garment workers in 109 Vietnamese factories between 2010 and 2014...
September 2016: Annals of Global Health
https://www.readbyqxmd.com/read/28281334/warm-cold-colonization-response-of-oaks-to-uplift-of-the-himalaya-hengduan-mountains
#8
Hong-Hu Meng, Tao Su, Xiao-Yang Gao, Jie Li, Xiao-Long Jiang, Hang Sun, Zhe-Kun Zhou
Clarifying the relationship between distribution patterns of organisms and geological events is critical to understanding the impact of environmental changes on organismal evolution. Quercus sect. Heterobalanus is now distributed across the Himalaya-Hengduan Mountains (HHM) and warm lowland in East China, yet how the distribution patterns of this group changed in response to the HHM uplift remains largely unknown. This study examines the effect of tectonic events in the HHM region on the oaks, providing a biological perspective on the geological history of this region...
June 2017: Molecular Ecology
https://www.readbyqxmd.com/read/28256601/complete-mitochondrial-sequences-from-mesolithic-sardinia
#9
Alessandra Modi, Francesca Tassi, Roberta Rosa Susca, Stefania Vai, Ermanno Rizzi, Gianluca De Bellis, Carlo Lugliè, Gloria Gonzalez Fortes, Martina Lari, Guido Barbujani, David Caramelli, Silvia Ghirotto
Little is known about the genetic prehistory of Sardinia because of the scarcity of pre-Neolithic human remains. From a genetic perspective, modern Sardinians are known as genetic outliers in Europe, showing unusually high levels of internal diversity and a close relationship to early European Neolithic farmers. However, how far this peculiar genetic structure extends and how it originated was to date impossible to test. Here we present the first and oldest complete mitochondrial sequences from Sardinia, dated back to 10,000 yBP...
March 3, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28237909/the-relationship-between-smoking-intensity-and-subclinical-cardiovascular-injury-the-multi-ethnic-study-of-atherosclerosis-mesa
#10
Mahmoud Al Rifai, Andrew P DeFillippis, John W McEvoy, Michael E Hall, Ana Navas Acien, Miranda R Jones, Rachel Keith, Hoda S Magid, Carlos J Rodriguez, Graham R Barr, Emelia J Benjamin, Rose Marie Robertson, Aruni Bhatnagar, Michael J Blaha
BACKGROUND AND AIMS: Modern tobacco regulatory science requires an understanding of which biomarkers of cardiovascular injury are most sensitive to cigarette smoking exposure. METHODS: We studied self-reported current smokers from the Multi-Ethnic Study of Atherosclerosis. Smoking intensity was defined by number of cigarettes/day and urinary cotinine levels. Subclinical cardiovascular injury was assessed using markers of inflammation [high-sensitivity C-reactive protein (hsCRP), interleukin 6 & 2 (IL-2 & IL-6), tumor necrosis factor alpha (TNF-α)], thrombosis (fibrinogen, D-dimer, homocysteine), myocardial injury (troponin T; TnT), endothelial damage (albumin: creatinine ratio), and vascular function [aortic & carotid distensibility, flow-mediated dilation (FMD)]...
March 2017: Atherosclerosis
https://www.readbyqxmd.com/read/28216996/busman-s-stomach-and-the-embodiment-of-modernity
#11
Rhodri Hayward
This paper examines the relationship between the gastric illness, 'busman's stomach' and the Coronation bus strike of May 1937 in which 27,000 London busworkers walked out for better working conditions and a seven-and-half-hour day. It explores the way in which new patterns of somatisation, gastroenterological techniques, psychological theories and competing understandings of time worked together to create new political institutions and new forms of political action in inter-war Britain.
January 2, 2017: Contemporary British History
https://www.readbyqxmd.com/read/28205612/dna-analysis-of-a-30-000-year-old-urocitellus-glacialis-from-northeastern-siberia-reveals-phylogenetic-relationships-between-ancient-and-present-day-arctic-ground-squirrels
#12
Marina Faerman, Gila Kahila Bar-Gal, Elisabetta Boaretto, Gennady G Boeskorov, Nikolai E Dokuchaev, Oleg A Ermakov, Fedor N Golenishchev, Stanislav V Gubin, Eugenia Mintz, Evgeniy Simonov, Vadim L Surin, Sergei V Titov, Oksana G Zanina, Nikolai A Formozov
In contrast to the abundant fossil record of arctic ground squirrels, Urocitellus parryii, from eastern Beringia, only a limited number of fossils is known from its western part. In 1946, unnamed GULAG prisoners discovered a nest with three mummified carcasses of arctic ground squirrels in the permafrost sediments of the El'ga river, Yakutia, Russia, that were later attributed to a new species, Citellus (Urocitellus) glacialis Vinogr. To verify this assignment and to explore phylogenetic relationships between ancient and present-day arctic ground squirrels, we performed (14)C dating and ancient DNA analyses of one of the El'ga mummies and four contemporaneous fossils from Duvanny Yar, northeastern Yakutia...
February 16, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28168123/a-new-glimpse-on-mesozoic-zooplankton-150-million-year-old-lobster-larvae
#13
Joachim T Haug, Carolin Haug
Larvae of malacostracan crustaceans represent a large fraction of modern day zooplankton. Plankton is not only a major part of the modern marine ecosystem, but must have played an important role in the ecosystems of the past as well. Unfortunately, our knowledge about plankton composition of the past is still quite limited. As an important part of today's zooplankton, malacostracan larvae are still a rarity in the fossil record; many types of malacostracan larvae dominating the modern plankton have so far not been found as fossils...
2017: PeerJ
https://www.readbyqxmd.com/read/28099442/a-whole-genome-dartseq-and-snp-analysis-for-genetic-diversity-assessment-in-durum-wheat-from-central-fertile-crescent
#14
Faheem Shehzad Baloch, Ahmad Alsaleh, Muhammad Qasim Shahid, Vahdettin Çiftçi, Luis E Sáenz de Miera, Muhammad Aasim, Muhammad Azhar Nadeem, Husnu Aktaş, Hakan Özkan, Rüştü Hatipoğlu
Until now, little attention has been paid to the geographic distribution and evaluation of genetic diversity of durum wheat from the Central Fertile Crescent (modern-day Turkey and Syria). Turkey and Syria are considered as primary centers of wheat diversity, and thousands of locally adapted wheat landraces are still present in the farmers' small fields. We planned this study to evaluate the genetic diversity of durum wheat landraces from the Central Fertile Crescent by genotyping based on DArTseq and SNP analysis...
2017: PloS One
https://www.readbyqxmd.com/read/28000096/relationship-between-tissue-distributions-of-modified-wuzi-yanzong-prescription-in-rats-and-meridian-tropism-theory
#15
Lin-Lin Wang, Wei-Wei Li, Cai-Sheng Wu, Jin-Lan Zhang, Yi-Xiang Song, Fang-Jiao Song, Hong Fu, Geng-Xin Liu, Xue-Mei Wang
OBJECTIVE: To investigate the relationship between tissue distributions of modified Wuzi Yanzong prescription (, MWP) in rats and meridian tropism theory. METHODS: A high-performance liquid chromatography with Fourier transform-mass spectrometry (HPLC-FT) method was used to identify the metabolites of MWP in different tissues of rats after continued oral administration of MWP for 7 days. The relationship between MWP and meridian tropism theory was studied according to the tissue distributions of the metabolites of MWP in rats and the relevant literature...
December 20, 2016: Chinese Journal of Integrative Medicine
https://www.readbyqxmd.com/read/27934774/the-moral-agency-of-institutions-effectively-using-expert-nurses-to-support-patient-autonomy
#16
Sonya Charles
Patient autonomy-with an emphasis on informed consent and the right to refuse treatment-is a cornerstone of modern bioethics. Within discussions about patient autonomy, feminist bioethicists have argued for a relational approach to autonomy. Under a relational framework, we must look beyond the individual moment of choice to include the role relationships and specific contexts can play in supporting or undermining autonomy. Given the day-to-day interactions they have with patients, nurses play a significant role in helping patients understand the nature of their illnesses and make truly informed decisions...
December 1, 2016: Journal of Medical Ethics
https://www.readbyqxmd.com/read/27857087/the-oral-microbiome-an-update-for-oral-healthcare-professionals
#17
M Kilian, I L C Chapple, M Hannig, P D Marsh, V Meuric, A M L Pedersen, M S Tonetti, W G Wade, E Zaura
For millions of years, our resident microbes have coevolved and coexisted with us in a mostly harmonious symbiotic relationship. We are not distinct entities from our microbiome, but together we form a 'superorganism' or holobiont, with the microbiome playing a significant role in our physiology and health. The mouth houses the second most diverse microbial community in the body, harbouring over 700 species of bacteria that colonise the hard surfaces of teeth and the soft tissues of the oral mucosa. Through recent advances in technology, we have started to unravel the complexities of the oral microbiome and gained new insights into its role during both health and disease...
November 18, 2016: British Dental Journal
https://www.readbyqxmd.com/read/27824859/the-strength-of-selection-against-neanderthal-introgression
#18
Ivan Juric, Simon Aeschbacher, Graham Coop
Hybridization between humans and Neanderthals has resulted in a low level of Neanderthal ancestry scattered across the genomes of many modern-day humans. After hybridization, on average, selection appears to have removed Neanderthal alleles from the human population. Quantifying the strength and causes of this selection against Neanderthal ancestry is key to understanding our relationship to Neanderthals and, more broadly, how populations remain distinct after secondary contact. Here, we develop a novel method for estimating the genome-wide average strength of selection and the density of selected sites using estimates of Neanderthal allele frequency along the genomes of modern-day humans...
November 2016: PLoS Genetics
https://www.readbyqxmd.com/read/27766937/leveraging-graph-topology-and-semantic-context-for-pharmacovigilance-through-twitter-streams
#19
Ryan Eshleman, Rahul Singh
BACKGROUND: Adverse drug events (ADEs) constitute one of the leading causes of post-therapeutic death and their identification constitutes an important challenge of modern precision medicine. Unfortunately, the onset and effects of ADEs are often underreported complicating timely intervention. At over 500 million posts per day, Twitter is a commonly used social media platform. The ubiquity of day-to-day personal information exchange on Twitter makes it a promising target for data mining for ADE identification and intervention...
October 6, 2016: BMC Bioinformatics
https://www.readbyqxmd.com/read/27723159/physical-activity-patterns-and-biomarkers-of-cardiovascular-disease-risk-in-hunter-gatherers
#20
David A Raichlen, Herman Pontzer, Jacob A Harris, Audax Z P Mabulla, Frank W Marlowe, J Josh Snodgrass, Geeta Eick, J Colette Berbesque, Amelia Sancilio, Brian M Wood
OBJECTIVES: Time spent in moderate-to-vigorous physical activity (MVPA) is a strong predictor of cardiovascular health, yet few humans living in industrialized societies meet current recommendations (150 min/week). Researchers have long suggested that human physiological requirements for aerobic exercise reflect an evolutionary shift to a hunting and gathering foraging strategy, and a recent transition to more sedentary lifestyles likely represents a mismatch with our past in terms of physical activity...
October 9, 2016: American Journal of Human Biology: the Official Journal of the Human Biology Council
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