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https://www.readbyqxmd.com/read/29135493/relationship-between-postoperative-pain-and-overall-30-day-complications-in-a-broad-surgical-population-an-observational-study
#1
Regina L M van Boekel, Michiel C Warlé, Renske G C Nielen, Kris C P Vissers, Rob van der Sande, Ewald M Bronkhorst, Jos G C Lerou, Monique A H Steegers
OBJECTIVE: The aim of this study was to establish the relationship between postoperative pain and 30-day postoperative complications. BACKGROUND: Only scarce data are available on the association between postoperative pain and a broad range of postoperative complications in a large heterogeneous surgical population. METHODS: Having postoperative pain was assessed in 2 ways: the movement-evoked pain score on the Numerical Rating Scale (NRS-MEP) and the patients' opinion whether the pain was acceptable or not...
November 13, 2017: Annals of Surgery
https://www.readbyqxmd.com/read/29118302/impact-of-the-relationship-between-the-defibrillation-threshold-dft-and-clinical-outcomes-in-recipients-of-modern-era-implantable-cardioverter-defibrillator-icd
#2
Yoshinari Enomoto, Mahito Noro, Masao Moroi, Masato Nakamura, Kaoru Sugi
Defibrillation threshold (DFT) testing during implantable cardioverter defibrillator (ICD) implantations is considered necessary for appropriate shock therapy and to measure the safety margin. However, the relationship between the DFT with modern era devices and the clinical outcome, including the total mortality is limited, which may lead to DFT testing itself being questioned. This study aimed to evaluate the relationship between the DFT and clinical outcome in ICD recipients.We enrolled 81 consecutive patients (66 males, aged 64...
November 8, 2017: International Heart Journal
https://www.readbyqxmd.com/read/29073058/big-data-modeling-to-predict-platelet-usage-and-minimize-wastage-in-a-tertiary-care-system
#3
Leying Guan, Xiaoying Tian, Saurabh Gombar, Allison J Zemek, Gomathi Krishnan, Robert Scott, Balasubramanian Narasimhan, Robert J Tibshirani, Tho D Pham
Maintaining a robust blood product supply is an essential requirement to guarantee optimal patient care in modern health care systems. However, daily blood product use is difficult to anticipate. Platelet products are the most variable in daily usage, have short shelf lives, and are also the most expensive to produce, test, and store. Due to the combination of absolute need, uncertain daily demand, and short shelf life, platelet products are frequently wasted due to expiration. Our aim is to build and validate a statistical model to forecast future platelet demand and thereby reduce wastage...
October 24, 2017: Proceedings of the National Academy of Sciences of the United States of America
https://www.readbyqxmd.com/read/29070451/arctic-antibiotic-resistance-gene-contamination-a-result-of-anthropogenic-activities-and-natural-origin
#4
Lu Tan, Linyun Li, Nicholas Ashbolt, Xiaolong Wang, Yuxiao Cui, Xiao Zhu, Yan Xu, Yang Yang, Daqing Mao, Yi Luo
The increasing global prevalence of antibiotic resistance genes (ARGs) in the environment is attributed to anthropogenic activities, particularly the misuse of antimicrobial drugs in human care and animal production. In the present study, we first examined Arctic/sub-Arctic (polar) sediments for the abundance and diversity of 30 ARGs against sulfonamide, tetracycline, aminoglycoside, quinolone, macrolide, and β-lactam antibiotics. Polar sediment ARGs were detected by qPCR at relatively low levels (10(-9) to 10(-5) copies/16S rRNA gene copies) compared to the reference sites, which were heavily impacted regions of China (the Haihe River, the Tianjin Water Park water and the Qilihai Wetland water, at 10(-8) to 10(-2) copies/16S rRNA gene copies)...
October 22, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/29033327/40-000-year-old-individual-from-asia-provides-insight-into-early-population-structure-in-eurasia
#5
Melinda A Yang, Xing Gao, Christoph Theunert, Haowen Tong, Ayinuer Aximu-Petri, Birgit Nickel, Montgomery Slatkin, Matthias Meyer, Svante Pääbo, Janet Kelso, Qiaomei Fu
By at least 45,000 years before present, anatomically modern humans had spread across Eurasia [1-3], but it is not well known how diverse these early populations were and whether they contributed substantially to later people or represent early modern human expansions into Eurasia that left no surviving descendants today. Analyses of genome-wide data from several ancient individuals from Western Eurasia and Siberia have shown that some of these individuals have relationships to present-day Europeans [4, 5] while others did not contribute to present-day Eurasian populations [3, 6]...
October 23, 2017: Current Biology: CB
https://www.readbyqxmd.com/read/29019456/introduction-paving-the-old-new-way-from-qing-to-china
#6
Ori Sela
The funeral procession of Sheng Xuanhuai (, 1844-1916) - the renowned Qing scholar-official, financier, and "father of Chinese industrialism" - meandered through the streets of Shanghai on 18 November 1917. The funeral was a grand event, one that was purportedly documented in film, later to be distributed as the first "news short-film" () in China. The North China Herald reported on the event in some detail, at times in rather florid language, and suggested that "the cortege was splendid and impressive, bringing back the days of the Manchu emperors...
September 2017: Science in Context
https://www.readbyqxmd.com/read/28967725/testicular-and-thyroid-function-as-survival-predictors-in-the-elderly-patient-candidate-to-surgery
#7
Antonio Aversa, Andrea Fabbri
The relationship between testosterone deficiency (TD) syndrome and surgical resilience has a great impact in the modern approach to male elderly patients. There is good evidence that low levels of T are a strong marker for cardiovascular risk; also, TD is frequently associated with increased cardiovascular and all-cause mortality especially in cardiac older frail men. Screening for low T should be mandatory in high risk groups candidate to surgery including those with diabetes, metabolic syndrome and obesity, even though benefits from T-treatment on survival rates are unclear...
July 18, 2017: Monaldi Archives for Chest Disease, Archivio Monaldi Per le Malattie del Torace
https://www.readbyqxmd.com/read/28958695/high-intake-of-dietary-advanced-glycation-end-products-is-associated-with-increased-arterial-stiffness-and-inflammation-in-subjects-with-type-2-diabetes
#8
A Di Pino, W Currenti, F Urbano, R Scicali, S Piro, F Purrello, A M Rabuazzo
BACKGROUND AND AIMS: Modern diets are high in advanced glycation end-products (dAGEs), derived from processing methods, exerting a pivotal role in promoting atherosclerotic risk. In this cross-sectional study we investigate the relationship between dAGE intake, arterial stiffness, inflammatory profile and macronutrient composition, in subjects with type 2 diabetes without overt cardiovascular disease. METHODS AND RESULTS: Arterial stiffness, carboxy-methyl-lysine, endogenous secretory receptor for AGEs (esRAGE), high sensitivity C reactive protein (hs-CRP), S100A12 and macronutrient intake were evaluated in 85 subjects with type 2 diabetes...
July 8, 2017: Nutrition, Metabolism, and Cardiovascular Diseases: NMCD
https://www.readbyqxmd.com/read/28953826/reflecting-on-the-humanities-related-to-experiences-of-illness-with-a-creative-exploration-of-metaphoric-spaces
#9
Mohamud A Verjee
Every patient has a story to tell, and every experienced physician has a bank of stories to recall. A patient's visit is not chance but a search for a cure, amelioration of state, advice, guidance, a prescription, or for seeking reassurance, comfort, and in some circumstances, permission to "be well". From the simplest tale to the most complex, narratives abound. Sometimes, the most intimate information shared with the physician confidante, go dark and deep, with a yearning to "tell all" after a period of suppression...
September 2017: Psychiatria Danubina
https://www.readbyqxmd.com/read/28918147/invited-review-effects-of-heat-stress-on-dairy-cattle-welfare
#10
Liam Polsky, Marina A G von Keyserlingk
The effects of high ambient temperatures on production animals, once thought to be limited to tropical areas, has extended into northern latitudes in response to the increasing global temperature. The number of days where the temperature-humidity index (THI) exceeds the comfort threshold (>72) is increasing in the northern United States, Canada, and Europe. Compounded by the increasing number of dairy animals and the intensification of production, heat stress has become one of the most important challenges facing the dairy industry today...
November 2017: Journal of Dairy Science
https://www.readbyqxmd.com/read/28902894/what-determines-sclerobiont-colonization-on-marine-mollusk-shells
#11
Vanessa Ochi Agostini, Matias do Nascimento Ritter, Alexandre José Macedo, Erik Muxagata, Fernando Erthal
Empty mollusk shells may act as colonization surfaces for sclerobionts depending on the physical, chemical, and biological attributes of the shells. However, the main factors that can affect the establishment of an organism on hard substrates and the colonization patterns on modern and time-averaged shells remain unclear. Using experimental and field approaches, we compared sclerobiont (i.e., bacteria and invertebrate) colonization patterns on the exposed shells (internal and external sides) of three bivalve species (Anadara brasiliana, Mactra isabelleana, and Amarilladesma mactroides) with different external shell textures...
2017: PloS One
https://www.readbyqxmd.com/read/28902892/neanderthal-and-denisova-tooth-protein-variants-in-present-day-humans
#12
Clément Zanolli, Mathilde Hourset, Rémi Esclassan, Catherine Mollereau
Environment parameters, diet and genetic factors interact to shape tooth morphostructure. In the human lineage, archaic and modern hominins show differences in dental traits, including enamel thickness, but variability also exists among living populations. Several polymorphisms, in particular in the non-collagenous extracellular matrix proteins of the tooth hard tissues, like enamelin, are involved in dental structure variation and defects and may be associated with dental disorders or susceptibility to caries...
2017: PloS One
https://www.readbyqxmd.com/read/28884802/a-female-viking-warrior-confirmed-by-genomics
#13
Charlotte Hedenstierna-Jonson, Anna Kjellström, Torun Zachrisson, Maja Krzewińska, Veronica Sobrado, Neil Price, Torsten Günther, Mattias Jakobsson, Anders Götherström, Jan Storå
OBJECTIVES: The objective of this study has been to confirm the sex and the affinity of an individual buried in a well-furnished warrior grave (Bj 581) in the Viking Age town of Birka, Sweden. Previously, based on the material and historical records, the male sex has been associated with the gender of the warrior and such was the case with Bj 581. An earlier osteological classification of the individual as female was considered controversial in a historical and archaeological context...
September 8, 2017: American Journal of Physical Anthropology
https://www.readbyqxmd.com/read/28783229/breaking-the-taboo-a-history-of-monetary-financing-in-canada-1930-1975
#14
Josh Ryan-Collins
Monetary financing - the funding of state expenditure via the creation of new money rather than through taxation or borrowing - has become a taboo policy instrument in advanced economies. It is generally associated with dangerously high inflation and/or war. Relatedly, a key institutional feature of modern independent central banks is that they are not obligated to support government expenditure via money creation. Since the financial crisis of 2007-2008, however, unorthodox monetary policies, in particular quantitative easing, coupled with stagnant growth and high levels of public and private debt have led to questions over the monetary financing taboo...
August 7, 2017: British Journal of Sociology
https://www.readbyqxmd.com/read/28757201/continuity-and-admixture-in-the-last-five-millennia-of-levantine-history-from-ancient-canaanite-and-present-day-lebanese-genome-sequences
#15
Marc Haber, Claude Doumet-Serhal, Christiana Scheib, Yali Xue, Petr Danecek, Massimo Mezzavilla, Sonia Youhanna, Rui Martiniano, Javier Prado-Martinez, Michał Szpak, Elizabeth Matisoo-Smith, Holger Schutkowski, Richard Mikulski, Pierre Zalloua, Toomas Kivisild, Chris Tyler-Smith
The Canaanites inhabited the Levant region during the Bronze Age and established a culture that became influential in the Near East and beyond. However, the Canaanites, unlike most other ancient Near Easterners of this period, left few surviving textual records and thus their origin and relationship to ancient and present-day populations remain unclear. In this study, we sequenced five whole genomes from ∼3,700-year-old individuals from the city of Sidon, a major Canaanite city-state on the Eastern Mediterranean coast...
August 3, 2017: American Journal of Human Genetics
https://www.readbyqxmd.com/read/28753828/risk-of-testosterone-flare-in-the-era-of-the-saturation-model-one-more-historical-myth
#16
REVIEW
Yonah Krakowsky, Abraham Morgentaler
CONTEXT: When luteinizing hormone-releasing hormone (LHRH) agonists were introduced in the 1980s, it was universally believed that the initial transient rise in serum testosterone (T), termed T flare, caused rapid prostate cancer (PCa) growth and led to disease progression, complications, and death. It became routine to offer antiandrogens (AAs) to prevent these risks. However, over the last decade, it has become recognized that androgens have a finite ability to stimulate PCa growth (the saturation model), providing a theoretical challenge to the risks of T flare...
July 1, 2017: European Urology Focus
https://www.readbyqxmd.com/read/28690059/the-relationship-between-norwegian-red-heifer-growth-and-their-first-lactation-test-day-milk-yield-a-field-study
#17
K S Storli, G Klemetsdal, H Volden, R Salte
Today's Norwegian Red (NR) is markedly different from the one that existed 25 yr ago due to the continuous genetic improvement of economically important traits. Still, current national recommendations on replacement heifer rearing largely are based on results from Danish studies from the late 1980s to the mid 1990s. The objectives of the present study were to gain information on (1) growth and growth profiles of modern NR replacement heifers in commercial dairy herds and (2) how growth during the rearing period affects the heifers' milk yield during their first lactation...
September 2017: Journal of Dairy Science
https://www.readbyqxmd.com/read/28687060/safety-limit-warning-levels-for-the-avoidance-of-excessive-sound-amplification-to-protect-against-further-hearing-loss
#18
Earl E Johnson
OBJECTIVE: To determine safe output sound pressure levels (SPL) for sound amplification devices to preserve hearing sensitivity after usage. DESIGN: A mathematical model consisting of the Modified Power Law (MPL) (Humes & Jesteadt, 1991 ) combined with equations for predicting temporary threshold shift (TTS) and subsequent permanent threshold shift (PTS) (Macrae, 1994b ) was used to determine safe output SPL. STUDY SAMPLE: The study involves no new human subject measurements of loudness tolerance or threshold shifts...
July 7, 2017: International Journal of Audiology
https://www.readbyqxmd.com/read/28521909/proximal-interphalangeal-joint-ankylosis-in-an-early-medieval-horse-from-wroc%C3%A5-aw-cathedral-island-poland
#19
Maciej Janeczek, Aleksander Chrószcz, Vedat Onar, Radomir Henklewski, Aleksandra Skalec
Animal remains that are unearthed during archaeological excavations often provide useful information about socio-cultural context, including human habits, beliefs, and ancestral relationships. In this report, we present pathologically altered equine first and second phalanges from an 11th century specimen that was excavated at Wrocław Cathedral Island, Poland. The results of gross examination, radiography, and computed tomography, indicate osteoarthritis of the proximal interphalangeal joint, with partial ankylosis...
June 2017: International Journal of Paleopathology
https://www.readbyqxmd.com/read/28484253/human-ancestry-correlates-with-language-and-reveals-that-race-is-not-an-objective-genomic-classifier
#20
Jennifer L Baker, Charles N Rotimi, Daniel Shriner
Genetic and archaeological studies have established a sub-Saharan African origin for anatomically modern humans with subsequent migrations out of Africa. Using the largest multi-locus data set known to date, we investigated genetic differentiation of early modern humans, human admixture and migration events, and relationships among ancestries and language groups. We compiled publicly available genome-wide genotype data on 5,966 individuals from 282 global samples, representing 30 primary language families. The best evidence supports 21 ancestries that delineate genetic structure of present-day human populations...
May 8, 2017: Scientific Reports
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