keyword
MENU ▼
Read by QxMD icon Read
search

rhinovirus infections in Children

keyword
https://www.readbyqxmd.com/read/29153065/-genotypes-of-rhinoviruses-in-children-and-adults-patients-with-acute-respiratory-tract-infections
#1
Eda Demirkan, Sevin Kırdar, Emel Ceylan, Ayşe Yenigün, İmran Kurt Ömürlü
Rhinovirus (RV) is one of the most frequent causative agent of acute respiratory tract infections in the world. The virus may cause a mild cold, as well as more serious clinical symptoms in patients with immune system deficiency or comorbidities. Rhinoviruses have been identified by molecular methods under three types: RV-A, RV-B and RV-C. In most of the cases, it was reported that RV-A and RV-C were related with lower respiratory tract infections and asthma exacerbations, while RV-B was rarely reported in lower respiratory tract infections...
October 2017: Mikrobiyoloji Bülteni
https://www.readbyqxmd.com/read/29149199/epidemiology-and-clinical-profile-of-pathogens-responsible-for-the-hospitalization-of-children-in-sousse-area-tunisia
#2
Ines Brini, Aida Guerrero, Naila Hannachi, Jihene Bouguila, Dorothea Orth-Höller, Amira Bouhlel, Lamia Boughamoura, Benjamin Hetzer, Wegene Borena, Britta Schiela, Dorothee Von Laer, Jalel Boukadida, Heribert Stoiber
This study aimed to identify a broad spectrum of respiratory pathogens from hospitalized and not-preselected children with acute respiratory tract infections in the Farhat Hached University-hospital of Sousse, Tunisia. Between September 2013 and December 2014, samples from 372 children aged between 1 month and 5 years were collected, and tested using multiplex real-time RT-PCR by a commercial assay for 21 respiratory pathogens. In addition, samples were screened for the presence of Streptococcus pneumoniae 16S rDNA using real-time PCR...
2017: PloS One
https://www.readbyqxmd.com/read/29143374/asthma-and-lung-function-in-adulthood-after-a-viral-wheezing-episode-in-early-childhood
#3
Katri Backman, Hertta Ollikainen, Eija Piippo-Savolainen, Kirsi Nuolivirta, Matti Korppi
BACKGROUND: Viral etiology of infection has a significant role in the long-term outcome of early-childhood wheezing. OBJECTIVE: This study examines asthma and lung function in adulthood after early-childhood wheezing induced by respiratory syncytial virus (RSV) and rhinovirus (RV). METHODS: A total of 100 children were hospitalized for a wheezing episode at less than 24 months of age from 1992 to 1993 in Kuopio University Hospital (Finland)...
November 16, 2017: Clinical and Experimental Allergy: Journal of the British Society for Allergy and Clinical Immunology
https://www.readbyqxmd.com/read/29131066/human-polyomavirus-wu-in-patients-with-respiratory-tract-infection-in-kuwait
#4
Sahar Essa, Wassim Chehadeh, Widad Al-Nakib
OBJECTIVE: To determine the circulating polyomavirus Washington University (WUV) strains among hospitalized patients with respiratory tract infections (RTI) in Kuwait. MATERIALS AND METHODS: Samples from 459 hospitalized children and adult patients with respiratory tract infections were screened for respiratory viruses by Polymerase chain reaction (PCR) techniques from April 2013 to April 2016. The VP2 gene from WUV-positive samples was sequenced and subjected to phylogenetic analysis...
November 7, 2017: Medical Principles and Practice: International Journal of the Kuwait University, Health Science Centre
https://www.readbyqxmd.com/read/29124902/t-cell-responses-against-rhinovirus-species-a-and-c-in-asthmatic-and-healthy-children
#5
Cibele M Gaido, Caitlyn Granland, Ingrid A Laing, Peter N Le Souëf, Wayne R Thomas, Andrew J Currie, Belinda J Hales
BACKGROUND: Infections by rhinovirus (RV) species A and C are the most common causes of exacerbations of asthma and a major cause of exacerbations of other acute and chronic respiratory diseases. Infections by both species are prevalent in pre-school and school-aged children and, particularly for RV-C, can cause severe symptoms and a need for hospitalization. While associations between RV infection and asthma are well established, the adaptive immune-mechanisms by which RV infections influence asthma exacerbations are yet to be defined...
November 10, 2017: Immunity, Inflammation and Disease
https://www.readbyqxmd.com/read/29121479/cdhr3-genetics-and-rhinovirus-c-respiratory-illnesses
#6
Klaus Bønnelykke, Amaziah T Coleman, Michael D Evans, Jonathan Thorsen, Johannes Waage, Nadja H Vissing, Christian J Carlsson, Jakob Stokholm, Bo L Chawes, Leon E Jessen, Thea K Fischer, Yury A Bochkov, Carole Ober, Robert F Lemanske, Daniel J Jackson, James E Gern, Hans Bisgaard
Background Experimental evidence suggests that CDHR3 is a receptor for rhinovirus-C (RV-C), and a missense variant in this gene (rs6967330) is associated with childhood asthma with severe exacerbations. Objective To determine whether rs6967330 influences RV-C infections and illnesses in early childhood. Methods We studied associations between rs6967330 and respiratory infections and illnesses in the COPSAC2010 and COAST birth cohorts, where respiratory infections were monitored prospectively for the first 3 years of life...
November 9, 2017: American Journal of Respiratory and Critical Care Medicine
https://www.readbyqxmd.com/read/29106589/a-multicenter-consortium-to-define-the-epidemiology-and-outcomes-of-inpatient-respiratory-viral-infections-in-pediatric-hematopoietic-stem-cell-transplant-recipients
#7
Brian T Fisher, Lara Danziger-Isakov, Leigh R Sweet, Flor M Munoz, Gabriela Maron, Elaine Tuomanen, Alistair Murray, Janet A Englund, Daniel Dulek, Natasha Halasa, Michael Green, Marian G Michaels, Rebecca Pellett Madan, Betsy C Herold, William J Steinbach
Background: Respiratory virus infections (RVIs) pose a threat to children undergoing hematopoietic stem cell transplantation (HSCT). In this era of sensitive molecular diagnostics, the incidence and outcome of HSCT recipients who are hospitalized with RVI (H-RVI) are not well described. Methods: A retrospective observational cohort of pediatric HSCT recipients (between January 2010 and June 2013) was assembled from 9 US pediatric transplant centers. Their medical charts were reviewed for H-RVI events within 1 year after their transplant...
July 1, 2017: Journal of the Pediatric Infectious Diseases Society
https://www.readbyqxmd.com/read/29069373/detection-of-influenza-c-viruses-among-outpatients-and-patients-hospitalized-for-severe-acute-respiratory-infection-minnesota-2013-2016
#8
Beth K Thielen, Hannah Friedlander, Sarah Bistodeau, Bo Shu, Brian Lynch, Karen Martin, Erica Bye, Kathyrn Como-Sabetti, David Boxrud, Anna K Strain, Sandra S Chaves, Andrea Steffens, Ashley L Fowlkes, Stephen Lindstrom, Ruth Lynfield
Background: Existing literature suggests that influenza C typically causes mild respiratory tract disease. However, clinical and epidemiological data are limited. Methods: Four outpatient clinics and three hospitals submitted clinical data and respiratory specimens through a surveillance network for acute respiratory infection (ARI) during May 2013 through December 2016. Specimens were tested using multi-target nucleic acid amplification tests (NAAT) for 19-22 respiratory pathogens, including influenza C...
October 23, 2017: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
https://www.readbyqxmd.com/read/29033350/phenotypical-characterization-of-human-rhinovirus-infections-in-severely-premature-children
#9
Geovanny F Perez, Bassem Kurdi, Rosemary Megalaa, Krishna Pancham, Shehlanoor Huseni, Natalia Isaza, Carlos E Rodriguez-Martinez, Dinesh Pillai, Gustavo Nino
BACKGROUND: Human Rhinovirus (HRV) has been identified as the most common cause of acute respiratory infections and hospitalizations in premature children. It is unclear if premature children are more susceptible to HRV due to their decreased pulmonary reserve or because they have enhanced lower airway reactivity to HRV. METHODS: We conducted a retrospective analysis of the clinical respiratory presentation of all PCR-confirmed HRV infections in full-term and premature children aged ≤3 years in our institution...
September 27, 2017: Pediatrics and Neonatology
https://www.readbyqxmd.com/read/29029245/host-transcription-profile-in-nasal-epithelium-and-whole-blood-of-hospitalised-children-under-two-years-of-age-with-respiratory-syncytial-virus-infection
#10
Lien Anh Ha Do, Johann Pellet, H Rogier van Doorn, Anh Tuan Tran, Bach Hue Nguyen, Thi Thu Loan Tran, Quynh Huong Tran, Quoc Bao Vo, Nguyen Anh Tran Dac, Hong Nhien Trinh, Thi Thanh Hai Nguyen, Bao Tinh Le Binh, Huu Mai Khanh Nguyen, Minh Tien Nguyen, Quang Tung Thai, Thanh Vu Vo, Ngoc Quang Minh Ngo, Thi Kim Huyen Dang, Ngoc Huong Cao, Thu Van Tran, Lu Viet Ho, Bertrand De Meulder, Charles Auffray, Jorrit-Jan Hofstra, Jeremy Farrar, Juliet E Bryant, Menno de Jong, Martin L Hibberd
Most insights into the cascade of immune events following acute respiratory syncytial virus (RSV) infection have been obtained from animal experiments or in vitro models. Here we investigated host gene expression profiles in nasopharyngeal swabs (NP) and whole blood samples during natural RSV and rhinovirus (hRV) infection (acute versus early recovery phase) in 83 hospitalised patients <2 years old with lower respiratory tract infections (LRTI). RSV infection induced strong and persistent innate immune responses including interferon signaling and pathways related to chemokine/cytokine signaling in both compartments...
September 27, 2017: Journal of Infectious Diseases
https://www.readbyqxmd.com/read/29020463/the-role-of-human-rhinovirus-hrv-species-on-asthma-exacerbation-severity-in-children-and-adolescents
#11
Katrina A Lambert, Luke A Prendergast, Shyamali C Dharmage, Mimi Tang, Molly O'Sullivan, Thomas Tran, Julian Druce, Philip Bardin, Michael J Abramson, Bircan Erbas
OBJECTIVE: It is recognized that human rhinovirus (HRV) infection is an important factor in asthma exacerbations requiring hospitalization in children. However, previous studies have disagreed on the differential impact of various HRV species. We sought to assess the impact of HRV species on the severity of asthma exacerbations in children and adolescents. We also examined whether the effect of HRV species on severity was modified by age and gender. METHODS: Virus strain was determined for 113 children with HRV detectable at the time of admission for asthma exacerbation...
October 11, 2017: Journal of Asthma: Official Journal of the Association for the Care of Asthma
https://www.readbyqxmd.com/read/28987219/role-of-viral-infections-in-the-development-and-exacerbation-of-asthma-in-children
#12
REVIEW
Tuomas Jartti, James E Gern
Viral infections are closely linked to wheezing illnesses in children of all ages. Respiratory syncytial virus (RSV) is the main causative agent of bronchiolitis, whereas rhinovirus (RV) is most commonly detected in wheezing children thereafter. Severe respiratory illness induced by either of these viruses is associated with subsequent development of asthma, and the risk is greatest for young children who wheeze with RV infections. Whether viral illnesses actually cause asthma is the subject of intense debate...
October 2017: Journal of Allergy and Clinical Immunology
https://www.readbyqxmd.com/read/28968668/rhinovirus-viremia-in-patients-hospitalized-with-community-acquired-pneumonia
#13
Xiaoyan Lu, Eileen Schneider, Seema Jain, Anna M Bramley, Weston Hymas, Chris Stockmann, Krow Ampofo, Sandra R Arnold, Derek J Williams, Wesley H Self, Anami Patel, James D Chappell, Carlos G Grijalva, Evan J Anderson, Richard G Wunderink, Jonathan A McCullers, Kathryn M Edwards, Andrew T Pavia, Dean D Erdman
Background: Rhinoviruses (RVs) are ubiquitous respiratory pathogens that often cause mild or subclinical infections. Molecular detection of RV from the upper respiratory tract can be prolonged, complicating etiologic association in persons with severe lower respiratory tract infections. Little is known about RV viremia and its value as a diagnostic indicator in persons hospitalized with community-acquired pneumonia (CAP). Methods: Sera from RV-positive children and adults hospitalized with CAP were tested for RV by real-time RT-PCR...
August 29, 2017: Journal of Infectious Diseases
https://www.readbyqxmd.com/read/28870461/enhanced-plasmacytoid-dendritic-cell-antiviral-responses-after-omalizumab
#14
Michelle A Gill, Andrew H Liu, Agustin Calatroni, Rebecca Z Krouse, Baomei Shao, Allison Schiltz, James E Gern, Alkis Togias, William W Busse
BACKGROUND: Atopy and viral respiratory tract infections synergistically promote asthma exacerbations. IgE cross-linking inhibits critical virus-induced IFN-α responses of plasmacytoid dendritic cells (pDCs), which can be deficient in patients with allergic asthma. OBJECTIVE: We sought to determine whether reducing IgE levels in vivo with omalizumab treatment increases pDC antiviral IFN-α responses in inner-city children with asthma. METHODS: PBMCs and pDCs isolated from children with exacerbation-prone asthma before and during omalizumab treatment were stimulated ex vivo with rhinovirus and influenza in the presence or absence of IgE cross-linking...
September 1, 2017: Journal of Allergy and Clinical Immunology
https://www.readbyqxmd.com/read/28864597/parvovirus-b19-infection-in-children-with-arterial-ischemic-stroke
#15
MULTICENTER STUDY
Heather J Fullerton, Jorge M Luna, Max Wintermark, Nancy K Hills, Rafal Tokarz, Ying Li, Carol Glaser, Gabrielle A DeVeber, W Ian Lipkin, Mitchell S V Elkind
BACKGROUND AND PURPOSE: Case-control studies suggest that acute infection transiently increases the risk of childhood arterial ischemic stroke. We hypothesized that an unbiased pathogen discovery approach utilizing MassTag-polymerase chain reaction would identify pathogens in the blood of childhood arterial ischemic stroke cases. METHODS: The multicenter international VIPS study (Vascular Effects of Infection in Pediatric Stroke) enrolled arterial ischemic stroke cases, and stroke-free controls, aged 29 days through 18 years...
October 2017: Stroke; a Journal of Cerebral Circulation
https://www.readbyqxmd.com/read/28852711/enterovirus-d68-in-viet-nam-2009-2015
#16
Nguyen Thi Han Ny, Nguyen To Anh, Vu Thi Ty Hang, Lam Anh Nguyet, Tran Tan Thanh, Do Quang Ha, Ngo Ngoc Quang Minh, Do Lien Anh Ha, Angela McBride, Ha Manh Tuan, Stephen Baker, Pham Thi Thanh Tam, Tran My Phuc, Dang Thao Huong, Tran Quoc Loi, Nguyen Tran Anh Vu, Nguyen Van Hung, Tran Thi Thuy Minh, Nguyen Van Xang, Nguyen Dong, Ho Dang Trung Nghia, Nguyen Van Vinh Chau, Guy Thwaites, H Rogier van Doorn, Catherine Anscombe, Tan Le Van
BACKGROUND: Since 1962, enterovirus D68 (EV-D68) has been implicated in multiple outbreaks and sporadic cases of respiratory infection worldwide, but especially in the USA and Europe with an increasing frequency between 2010 and 2014. We describe the detection, associated clinical features and molecular characterization of EV-D68 in central and southern Viet Nam between 2009 and 2015. METHODS: Enterovirus/rhinovirus PCR positive respiratory or CSF samples taken from children and adults with respiratory/central nervous system infections in Viet Nam were tested by an EV-D68 specific PCR...
2017: Wellcome Open Research
https://www.readbyqxmd.com/read/28822736/-rhinovirus-underestimated-pathogens-in-patients-during-the-neonatal-period
#17
S Zacharie, A Vabret, B Guillois, C Dupont, J Brouard
INTRODUCTION: In recent years, developments in virological tools have led to the easy detection of rhinoviruses and enteroviruses (E/RV). Their detection is very frequent in cases of airway involvement in children and their demonstrated causality. But the morbidity of E/RV in the neonatal period is unknown due to lack of epidemiological data. The objective of this study was to evaluate the incidence and clinical characteristics of these infections in hospitalized neonates. MATERIALS AND METHODS: We retrospectively analyzed the virology specimens of all neonates hospitalized at the Caen University Hospital between 2006 and 2011...
September 2017: Archives de Pédiatrie: Organe Officiel de la Sociéte Française de Pédiatrie
https://www.readbyqxmd.com/read/28750058/human-enteroviruses-associated-with-and-without-diarrhea-in-thailand-between-2010-and-2016
#18
Jira Chansaenroj, Supansa Tuanthap, Thanundorn Thanusuwannasak, Ausanee Duang-In, Sirapa Klinfueng, Napha Thaneskongtong, Viboonsuk Vutithanachot, Sompong Vongpunsawad, Yong Poovorawan
Non-bacterial acute gastroenteritis (AGE) associated with virus infection affects individuals living in developing countries, especially children. To investigate whether shedding of certain human enterovirus (EV) is more frequently detected in the stool of individuals with AGE of unknown etiology than individuals without AGE symptoms, we tested fecal samples collected from 2,692 individuals with diarrhea between January 2010 and December 2016. Samples were tested for rotavirus, norovirus, and EV by reverse-transcription polymerase chain reaction (RT-PCR) and adenovirus by PCR...
2017: PloS One
https://www.readbyqxmd.com/read/28747261/enterovirus-d68-infection-in-a-cluster-of-children-with-acute-flaccid-myelitis-buenos-aires-argentina-2016
#19
Victor Ruggieri, Maria Ivana Paz, María Gabriela Peretti, Carlos Rugilo, Rosa Bologna, Cecilia Freire, Silvana Vergel, Andrea Savransky
OBJECTIVE: To report a outbreak of 11 cases of acute asymmetric flaccid myelopathy due to spinal motor neuron injury. MATERIAL AND METHODS: Eleven children, six male, with a mean age of 3 years presented with acute flaccid myelitis. We analyzed clinical features, etiology, neuroradiological images, treatment, and outcome. RESULTS: Nine children had bilateral and asymmetric flaccid myelitis of the upper limbs, 1 had upper limb monoplegia, and 1 presented with hemiparesis...
November 2017: European Journal of Paediatric Neurology: EJPN
https://www.readbyqxmd.com/read/28726613/human-metapneumovirus-and-other-respiratory-viral-infections-during-pregnancy-and-birth-nepal
#20
Jennifer L Lenahan, Janet A Englund, Joanne Katz, Jane Kuypers, Anna Wald, Amalia Magaret, James M Tielsch, Subarna K Khatry, Stephen C LeClerq, Laxman Shrestha, Mark C Steinhoff, Helen Y Chu
Human metapneumovirus (HMPV) is a respiratory virus that can cause severe lower respiratory tract disease and even death, primarily in young children. The incidence and characteristics of HMPV have not been well described in pregnant women. As part of a trial of maternal influenza immunization in rural southern Nepal, we conducted prospective, longitudinal, home-based active surveillance for febrile respiratory illness during pregnancy through 6 months postpartum. During 2011-2014, HMPV was detected in 55 of 3,693 women (16...
August 2017: Emerging Infectious Diseases
keyword
keyword
82963
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"