keyword
MENU ▼
Read by QxMD icon Read
search

rhinovirus infections in Children

keyword
https://www.readbyqxmd.com/read/28237484/viral-co-infections-among-children-with-confirmed-measles-at-hospitals-in-hanoi-vietnam-2014
#1
Le Khanh Nguyen Hang, Loan Phuong Do, Thanh Thi Trieu Van, Son Vu Nguyen, Phuong Vu Mai Hoang, Hien Thi Pham, Thanh Thi Le, Huong Thi Thu Tran, Cuong Duc Vuong, Thi Quynh Le Mai
OBJECTIVE: To characterize viral co-infections among representative hospitalized measles cases during the 2014 Hanoi outbreak. METHODS: Throat swabs were collected from 54 pediatric patients with confirmed measles, and molecular diagnostics performed for 10 additional viral respiratory pathogens (Influenza A/H1N1pdm09; A/H3N2 and influenza B; Parainfluenza 1, 2, 3; Respiratory Synctial Virus, RSV; human Metapneumovirus, hMPV; Adenovirus and Picornavirus). RESULTS: Twenty-one cases (38...
February 2017: Asian Pacific Journal of Tropical Medicine
https://www.readbyqxmd.com/read/28213960/association-of-rhinovirus-with-exacerbations-in-young-children-affected-by-cystic-fibrosis-preliminary-data
#2
Sacha Stelzer-Braid, Nancy Liu, Michael Doumit, Russell D'Cunha, Yvonne Belessis, Adam Jaffe, William D Rawlinson
Rhinovirus (RV) is a common respiratory viral infection linked to worsening of chronic respiratory diseases including cystic fibrosis (CF) and asthma. RV was tested by RT-PCR in samples (n = 465) collected from the upper (nasal swab, oropharyngeal suction and sputum) and lower (bronchoalveolar washings) respiratory tract of 110 children with CF. Air samples (n = 52) collected from the operating theatres and outpatient clinics were tested for RV. RV was found in 43% of children <5 years suffering an exacerbation, and 12% of older children (5-17 years)...
February 18, 2017: Journal of Medical Virology
https://www.readbyqxmd.com/read/28193180/viral-aetiology-of-bronchiolitis-in-hospitalised-children-in-qatar
#3
Ibrahim Janahi, Anas Abdulkayoum, Fawziya Almeshwesh, Mohamed Alkuwari, Ahmed Al Hammadi, Marwah Alameri
BACKGROUND: Bronchiolitis is considered one of the earliest and most common causes of hospitalisation in young children. Development of molecular technologies allowed a better understanding of bronchiolitis aetiology. Results from cohort studies evaluating the association between single, multiple viral infections and clinical outcomes are conflicting. Data on viral bronchiolitis in children were found to be limited in Qatar. This study aimed to determine frequency and seasonal trends of viral pathogens causing acute bronchiolitis, and to explore association between viral pathogens, disease severity and length of stay (LOS)...
February 13, 2017: BMC Infectious Diseases
https://www.readbyqxmd.com/read/28187115/clinical-course-of-enterovirus-d68-in-hospitalized-children
#4
Jennifer E Schuster, Rangaraj Selvarangan, Ferdaus Hassan, Kayla B Briggs, Lindsay Hays, Jenna O Miller, Barbara Pahud, Henry T Puls, Mary Ann Queen, Marita T Thompson, Gina Weddle, Mary Anne Jackson
BACKGROUND: Enterovirus D68 (EV-D68) has been sporadically reported as a cause of respiratory tract infections. In 2014, an international outbreak of EV-D68 occurred and caused severe respiratory disease in the pediatric population. METHODS: A retrospective chart review was performed of children admitted to Children's Mercy Hospital from August 1, 2014, to September 15, 2014, with positive multiplex polymerase chain reaction testing for EV/rhinovirus (RV). Specimens were subsequently tested for EV-D68, and clinical data were obtained from the medical records...
March 2017: Pediatric Infectious Disease Journal
https://www.readbyqxmd.com/read/28187065/clinical-course-of-enterovirus-d68-in-hospitalized-children
#5
Jennifer E Schuster, Rangaraj Selvarangan, Ferdaus Hassan, Kayla B Briggs, Lindsay Hays, Jenna O Miller, Barbara Pahud, Henry T Puls, Mary Ann Queen, Marita T Thompson, Gina Weddle, Mary Anne Jackson
BACKGROUND: Enterovirus D68 (EV-D68) has been sporadically reported as a cause of respiratory tract infections. In 2014, an international outbreak of EV-D68 occurred and caused severe respiratory disease in the pediatric population. METHODS: A retrospective chart review was performed of children admitted to Children's Mercy Hospital from August 1-September 15, 2014 with positive multiplex PCR testing for enterovirus/rhinovirus (EV/RV). Specimens were subsequently tested for EV-D68, and clinical data were obtained from the medical records...
December 13, 2016: Pediatric Infectious Disease Journal
https://www.readbyqxmd.com/read/28155195/clinical-evaluation-of-the-isothermal-amplification-assays-for-the-detection-of-four-common-respiratory-viruses-in-children-with-pneumonia
#6
Hangyu Zhou, Mengchuan Zhao, Xinna Li, Dan Zhang, Shuaifeng Zhou, Chen Chen, Zhishan Feng, Xuejun Ma
Respiratory viruses are recognized as serious causes of morbidity and mortality in lower respiratory tract infections in patients. Isothermal amplification assays are increasingly used in their detection because of their rapidity, simplicity and cost-effectiveness, when compared to traditional molecular diagnostic methods. However, systematic assessment of these assays in the clinical settings is rarely reported. MEDLINE (Pubmed) searches were done analysing subject headings and words in the abstract related to isothermal amplification assay and virus...
February 2, 2017: Archives of Virology
https://www.readbyqxmd.com/read/28132571/the-diagnosis-and-management-of-respiratory-viral-infections-in-cystic-fibrosis
#7
William Flight, Andrew Jones
Respiratory viruses, such as those that cause influenza and the common cold, are a regular feature of life for the entire human population. Among people with CF, these viruses are associated with prolonged respiratory illness and show a clear association with pulmonary exacerbations which in turn are associated with lung function decline and risk of death. Human rhinovirus is the most commonly encountered respiratory viral pathogen in CF although adenovirus, bocavirus, coronavirus, influenza, parainfluenza, metapneumovirus and respiratory syncytial virus are all also responsible for infections in this population...
February 3, 2017: Expert Review of Respiratory Medicine
https://www.readbyqxmd.com/read/28121929/correlation-of-symptomatic-enterovirus-infection-and-later-risk-of-allergic-diseases-via-a-population-based-cohort-study
#8
Zon-Min Lee, Ying-Hsien Huang, Shu-Chen Ho, Ho-Chang Kuo
Infants who are exposed to the rhinovirus or respiratory syncytial virus are at a higher risk of subsequently developing wheezing or asthma. This study aims to determine whether preschoolers with a history of symptomatic enterovirus infection are at an increased risk of developing allergic diseases or not.We used data from the Taiwan National Health Insurance Research Database from 1999 to 2006 for this nationwide population-based cohort study. The subsequent risks for allergic diseases, which included asthma (International Classification of Diseases [ICD]-9: 493...
January 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28118832/in-vitro-screening-for-antiviral-activity-of-turkish-plants-revealing-methanolic-extract-of-rindera-lanata-var-lanata-active-against-human-rotavirus
#9
Andrea Civra, Rachele Francese, Davide Sinato, Manuela Donalisio, Valeria Cagno, Patrizia Rubiolo, Ramazan Ceylan, Ahmet Uysal, Gokhan Zengin, David Lembo
BACKGROUND: Human rotavirus (HRoV) is the leading cause of severe gastroenteritis in infants and children under the age of five years. No specific antiviral drug is available for HRoV infections and the treatment of viral diarrhea is mainly based on rehydration and zinc treatment. In this study, we explored medicinal plants endemic to Turkey flora as a source of anti-HRoV compunds. METHODS: We performed an antiviral screening on Ballota macrodonta, Salvia cryptantha and Rindera lanata extracts by focus reduction assay...
January 24, 2017: BMC Complementary and Alternative Medicine
https://www.readbyqxmd.com/read/28100615/rhinovirus-c-asthma-and-cell-surface-expression-of-virus-receptor-cdhr3
#10
Ann C Palmenberg
Human rhinoviruses of the A, B, and C species are defined agents of the common cold. But more than that, the RV-A and RV-C are the dominant cause of hospitalization-category infections in young children, especially those with asthma. The RV-C use of cadherin-related family member 3 (CDHR3) as its cellular receptor, creates a direct phenotypic link between human genetics ("G" vs "A" alleles cause Cys529 vs Tyr529 protein variants) and the efficiency with which RV-C can infect cells. With a lower cell surface display density, the human-specific Cys529 variant apparently confers partial protection from the severest virus-induced asthma episodes...
January 18, 2017: Journal of Virology
https://www.readbyqxmd.com/read/28077283/aetiology-of-febrile-pharyngitis-in-children-potential-of-myxovirus-resistance-protein-a-mxa-as-a-biomarker-of-viral-infection
#11
Lauri Ivaska, Jussi Niemelä, Johanna Lempainen, Riikka Österback, Matti Waris, Tytti Vuorinen, Jukka Hytönen, Kaisu Rantakokko-Jalava, Ville Peltola
OBJECTIVES: Besides group A streptococcus (GAS), microbial causes of pharyngitis in children are not well known. We aimed to document the viral and bacterial aetiology of pharyngitis and to assess the pathogenic role of viruses by determining the myxovirus resistance protein A (MxA) in the blood as a marker of interferon response. METHODS: In this prospective observational study, throat swabs and blood samples were collected from children (age 1-16 years) presenting to the emergency department with febrile pharyngitis...
January 7, 2017: Journal of Infection
https://www.readbyqxmd.com/read/28040689/burden-of-healthcare-associated-viral-respiratory-infections-in-children-s-hospitals
#12
Caroline Quach, Rita Shah, Lorry G Rubin
OBJECTIVE: Although healthcare-associated (HA) viral respiratory infections (VRIs) are common in pediatrics, no benchmark for comparison exists. We aimed to determine, compare, and assess determinants of unit-specific HA-VRI incidence rates in 2 children's hospitals. METHODS: This study was a retrospective comparison of prospective cohorts. The Montreal Children's Hospital and the Cohen Children's Medical Center of New York perform prospective surveillance for HA-VRI using standardized definitions that require the presence of symptoms compatible with VRI and virus detection...
December 30, 2016: Journal of the Pediatric Infectious Diseases Society
https://www.readbyqxmd.com/read/28028115/epidemiologic-analysis-of-respiratory-viral-infections-mainly-in-hospitalized-children-and-adults-in-a-midwest-university-medical-center-after-the-implementation-of-a-14-virus-multiplex-nucleic-acid-amplification-test
#13
Sophie Arbefeville, Patricia Ferrieri
OBJECTIVES: To investigate the etiology of viral respiratory tract infections mainly in hospitalized children and adults over a 12-month consecutive period after implementation of a 14-virus multiplex nucleic acid amplification test. METHODS: From January 2014 to January 2015, a total of 2,237 respiratory samples were analyzed with the US Food and Drug Administration-cleared eSensor Respiratory Viral Panel (GenMark Diagnostics, Carlsbad, CA). RESULTS: Of the 2,237 specimens tested, 788 specimens were positive for at least one virus, giving a positivity rate of 35...
December 27, 2016: American Journal of Clinical Pathology
https://www.readbyqxmd.com/read/28027280/clinical-and-virus-surveillance-after-the-first-wheezing-episode-special-reference-to-rhinovirus-a-and-c-species
#14
Riitta Turunen, Tytti Vuorinen, Yury Bochkov, James Gern, Tuomas Jartti
BACKGROUND: Susceptibility to rhinovirus (RV) induced early wheezing episode has been recognized as an important risk factor for asthma but the data on different RV species are limited. Our aim was to investigate the risk for recurrences in first-time wheezing children with special focus on RV species. METHODS: First-time wheezing children (88/23 in-/outpatients) were prospectively followed at 2-week, 2-month and 12-month time-points, and at first recurrence within 12 months...
December 23, 2016: Pediatric Infectious Disease Journal
https://www.readbyqxmd.com/read/28024227/the-role-of-outdoor-fungi-on-asthma-hospital-admissions-in-children-and-adolescents-a-5-year-time-stratified-case-crossover-analysis
#15
Rachel Tham, Constance H Katelaris, Don Vicendese, Shyamali C Dharmage, Adrian J Lowe, Gayan Bowatte, Philip Taylor, Pamela Burton, Michael J Abramson, Bircan Erbas
BACKGROUND: Some fungal spores can trigger asthma exacerbation but knowledge of which outdoor fungal spores contribute to asthma hospitalisation is limited. OBJECTIVES: To examine the role of outdoor fungal spores in child and adolescent asthma hospitalisations. METHODS: We conducted a bi-directional time-stratified case-crossover study of child and adolescent asthma hospitalisations over 5 years. Conditional logistic regression assessed the role of 20 fungi taxa (Same day [L0] and lagged [L1-3]) adjusted for maximum temperature, humidity and grass pollen...
April 2017: Environmental Research
https://www.readbyqxmd.com/read/28018433/viral-agents-causing-acute-respiratory-infections-in-children-under-five-a-study-from-eastern-india
#16
Pravakar Mishra, Lipika Nayak, Rashmi Ranjan Das, Bhagirathi Dwibedi, Amitabh Singh
Background. Acute respiratory infections (ARIs) are important cause of mortality and morbidity in children under five in developing country. Methods. This observational study was conducted over two-year period in a tertiary care teaching hospital of Eastern India. Nasal and throat swabs were collected, transported to the laboratory at 2-8°C in viral transport media, and then processed for detection of viruses using mono/multiplex real-time polymerase chain reaction. Results. A total of 300 children aged 2-60 months with ARIs were included...
2016: International Journal of Pediatrics
https://www.readbyqxmd.com/read/27997520/polymorphisms-of-mannose-binding-lectin-and-toll-like-receptors-2-3-4-7-and-8-and-the-risk-of-respiratory-infections-and-acute-otitis-media-in-children
#17
Laura Toivonen, Juho Vuononvirta, Jussi Mertsola, Matti Waris, Qiushui He, Ville Peltola
BACKGROUND: Mannose-binding lectin (MBL) and toll-like receptors (TLR) are important components of the innate immune system. We assessed the susceptibility of children with genetic variants in these factors to respiratory infections, rhinovirus infections, and acute otitis media. METHODS: In a prospective cohort study, blood samples from 381 Finnish children were analyzed for polymorphisms in MBL2 at codons 52, 54, and 57, TLR2 Arg753Gln, TLR3 Leu412Phe, TLR4 Asp299Gly, TLR7 Gln11Leu, and TLR8 Leu651Leu...
December 15, 2016: Pediatric Infectious Disease Journal
https://www.readbyqxmd.com/read/27992067/the-role-of-rhinoviruses-is-overestimated-in-the-aetiology-of-community-acquired-pneumonia-in-children
#18
Matti Korppi
No abstract text is available yet for this article.
December 19, 2016: Acta Paediatrica
https://www.readbyqxmd.com/read/27936016/a-tool-for-investigating-asthma-and-copd-exacerbations-a-newly-manufactured-and-well-characterised-gmp-wild-type-human-rhinovirus-for-use-in-the-human-viral-challenge-model
#19
Daniel J Fullen, Bryan Murray, Julie Mori, Andrew Catchpole, Daryl W Borley, Edward J Murray, Ganesh Balaratnam, Anthony Gilbert, Alex Mann, Fiona Hughes, Rob Lambkin-Williams
BACKGROUND: Human Rhinovirus infection is an important precursor to asthma and chronic obstructive pulmonary disease exacerbations and the Human Viral Challenge model may provide a powerful tool in studying these and other chronic respiratory diseases. In this study we have reported the production and human characterisation of a new Wild-Type HRV-16 challenge virus produced specifically for this purpose. METHODS AND STOCK DEVELOPMENT: A HRV-16 isolate from an 18 year old experimentally infected healthy female volunteer (University of Virginia Children's Hospital, USA) was obtained with appropriate medical history and consent...
2016: PloS One
https://www.readbyqxmd.com/read/27927871/severity-of-respiratory-syncytial-virus-lower-respiratory-tract-infection-with-viral-coinfection-in-hiv-uninfected-children
#20
Natalie I Mazur, Louis Bont, Adam L Cohen, Cheryl Cohen, Anne von Gottberg, Michelle J Groome, Orienka Hellferscee, Kerstin Klipstein-Grobusch, Omphile Tschegofatso Mekgoe, Fathima Naby, Jocelyn Moyes, Stefano Tempia, Florette K Treurnicht, Marietje Venter, Sibongile Walaza, Nicole Wolter, Shabir A Madhi
BACKGROUND: Molecular diagnostics enable sensitive detection of respiratory viruses but their clinical significance remains unclear in pediatric lower respiratory tract infections (LRTI). We aimed to determine whether viral coinfections increased life-threatening disease in a large cohort. METHODS: Molecular testing was performed for respiratory viruses in nasopharyngeal aspirates collected from children aged <5 years within 24 hours of hospital admission during sentinel surveillance for Severe Acute Respiratory Illness (SARI) hospitalisation conducted in South Africa during February 2009-December 2013...
December 7, 2016: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
keyword
keyword
82963
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"