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antiemetic propofol

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https://www.readbyqxmd.com/read/29094418/total-intravenous-anesthesia-vs-single-pharmacological-prophylaxis-to-prevent-postoperative-vomiting-in-children-a-systematic-review-and-meta-analysis
#1
REVIEW
Maximilian S Schaefer, Peter Kranke, Stephanie Weibel, Robert Kreysing, Janika Ochel, Peter Kienbaum
BACKGROUND: Postoperative nausea and postoperative vomiting are frequent but often missed complications after general anesthesia in pediatric patients. Because inhaled anesthetics are known to trigger postoperative vomiting, total intravenous anesthesia is often administered in high-risk children to avoid the use of inhalational anesthesia. Since inhalational anesthesia might be advantageous in some situations, the question is raised whether administration of pharmacological prophylaxis offers equal protection from postoperative vomiting compared with total intravenous anesthesia alone...
December 2017: Paediatric Anaesthesia
https://www.readbyqxmd.com/read/28728322/perioperative-hypertension-management-during-facelift-under-local-anesthesia-with-intravenous-hypnotics
#2
Ki Ho Chung, Myeong Soo Cho, Hoon Jin
Perioperative hypertension is a phenomenon in which a surgical patient's blood pressure temporarily increases throughout the preoperative and postoperative periods and remains high until the patient's condition stabilizes. This phenomenon requires immediate treatment not only because it is observed in a majority of patients who are not diagnosed with high blood pressure, but also because occurs in patients with underlying essential hypertension who show a sharp increase in their blood pressure. The most common complication following facelift surgery is hematoma, and the most critical risk factor that causes hematoma is elevated systolic blood pressure...
July 2017: Archives of Plastic Surgery
https://www.readbyqxmd.com/read/28701596/propofol-versus-ketofol-for-sedation-of-pediatric-patients-undergoing-transcatheter-pulmonary-valve-implantation-a-double-blind-randomized-study
#3
Rabie Soliman, Mohammed Mofeed, Tarek Momenah
OBJECTIVE: The study was done to compare propofol and ketofol for sedation of pediatric patients scheduled for elective pulmonary valve implantation in a catheterization laboratory. DESIGN: This was a double-blind randomized study. SETTING: This study was conducted in Prince Sultan Cardiac Centre, Saudi Arabia. PATIENTS AND METHODS: The study included 60 pediatric patients with pulmonary regurge undergoing pulmonary valve implantation...
July 2017: Annals of Cardiac Anaesthesia
https://www.readbyqxmd.com/read/28500750/nausea-and-vomiting-in-children-and-adolescents-receiving-intrathecal-methotrexate-a-prospective-observational-study
#4
COMMENT
Jacqueline Flank, Komail Nadeem, Sheliza Moledina, Mila Khanna, Christina Schindera, Angela Punnett, L Lee Dupuis
BACKGROUND: The prevalence of nausea and vomiting after receipt of intrathecal methotrexate (IT-MTX) in pediatric oncology patients is unknown. METHODS: Patients (4-18 years) about to receive IT-MTX were eligible to participate in this prospective, observational study. Patients received antiemetics as prescribed by their clinical team. Nausea severity (patient-assessed), timing of emetic episodes, and administration of antiemetics were recorded beginning immediately prior to IT-MTX administration, for the next 24 hr (acute phase), and for a maximum of 7 additional days (delayed phase)...
October 2017: Pediatric Blood & Cancer
https://www.readbyqxmd.com/read/28389799/effects-of-hypercapnia-on-postoperative-nausea-and-vomiting-after-laparoscopic-surgery-a-double-blind-randomized-controlled-study
#5
Ji-Seon Son, Ji-Yun Oh, Seonghoon Ko
BACKGROUND: Laparoscopic surgery is associated with a high incidence of postoperative nausea and vomiting (PONV). The use of CO2 pneumoperitoneum has been proposed as a potential cause of high PONV incidence. However, intraoperative hypercarbia may be related to enhanced perfusion to the main effector sites for PONV, including the brain and gastrointestinal tract. In this study, we investigated whether an increase in intraoperative CO2 partial pressure in arterial blood (PaCO2) reduces the incidence of PONV...
November 2017: Surgical Endoscopy
https://www.readbyqxmd.com/read/28024715/incidence-of-postoperative-nausea-and-vomiting-following-gynecological-laparoscopy-a-comparison-of-standard-anesthetic-technique-and-propofol-infusion
#6
RANDOMIZED CONTROLLED TRIAL
Pradipta Bhakta, Bablu Rani Ghosh, Umesh Singh, Preeti S Govind, Abhinav Gupta, Kulwant Singh Kapoor, Rajesh Kumar Jain, Tulsi Nag, Dipanwita Mitra, Manjushree Ray, Vikash Singh, Gauri Mukherjee
OBJECTIVE: To determine the safety, efficacy, and feasibility of propofol-based anesthesia in gynecological laparoscopies in reducing incidences of postoperative nausea and vomiting compared to a standard anesthesia using thiopentone/isoflurane. DESIGN: Randomized single-blind (for anesthesia techniques used) and double-blind (for postoperative assessment) controlled trial. SETTING: Operation theater, postanesthesia recovery room, teaching hospital...
December 2016: Acta Anaesthesiologica Taiwanica: Official Journal of the Taiwan Society of Anesthesiologists
https://www.readbyqxmd.com/read/27650295/a-randomized-double-blind-trial-evaluating-the-efficacy-of-palonosetron-with-total-intravenous-anesthesia-using-propofol-and-remifentanil-for-the-prevention-of-postoperative-nausea-and-vomiting-after-gynecologic-surgery
#7
RANDOMIZED CONTROLLED TRIAL
Yun-Sic Bang, Young Uk Kim, Dawoon Oh, Eui Yong Shin, Soo Kyoung Park
PURPOSE: Palonosetron has potent and long-acting antiemetic effects for postoperative nausea and vomiting (PONV). The aim of this study was to prospectively evaluate the efficacy of palonosetron when used with total intravenous anesthesia (TIVA) using propofol and remifentanil for the prevention of PONV in patients undergoing laparoscopic gynecologic surgery. METHODS: This prospective double-blind study comprised 100 female American Society of Anesthesiologist physical status I and II patients who were undergoing laparoscopic gynecologic surgery under TIVA...
December 2016: Journal of Anesthesia
https://www.readbyqxmd.com/read/27454663/total-intravenous-anaesthesia-versus-single-drug-pharmacological-antiemetic-prophylaxis-in-adults-a-systematic-review-and-meta-analysis
#8
Maximilian S Schaefer, Peter Kranke, Stephanie Weibel, Robert Kreysing, Peter Kienbaum
BACKGROUND: Postoperative nausea and vomiting (PONV) are among the most unfavourable anaesthetic outcomes attributed to the administration of inhaled anaesthetics. Accordingly, inhaled anaesthetics are frequently substituted by propofol when patients are at risk of PONV. As, on some occasions, inhalational anaesthesia may be favourable, the relative impact of propofol anaesthesia needs to be established based on robust data. OBJECTIVE: To compare the effectiveness of a single-drug pharmacological prophylaxis with total intravenous anaesthesia (TIVA) for prevention of PONV...
October 2016: European Journal of Anaesthesiology
https://www.readbyqxmd.com/read/27295547/-ponv-after-strabismus-surgery-risk-adapted-prophylaxis
#9
R Wolf, E Morinello, G Kestler, B Käsmann-Kellner, M Bischoff, T Hager, J Schöpe, L H J Eberhart
BACKGROUND: Following strabismus surgery, patients frequently develop variable degrees of postoperative nausea and vomiting (PONV). These symptoms cause discomfort and result in serious complications such as intramuscular bleeding and subconjunctival hemorrhage. In children long lasting PONV can lead to and electrolyte imbalance and dehydration. A prolonged course of recovery is the consequence. For the hospital, PONV can also involve negative economic impacts because of a damaged public reputation of the institution...
July 2016: Der Anaesthesist
https://www.readbyqxmd.com/read/27282013/generation-z-adolescent-xenobiotic-abuse-in-the-21st-century
#10
REVIEW
William Eggleston, Christine Stork
NMDA receptor antagonists include the prescription medication ketamine, the illicit xenobiotics PCP, MXE, and other novel PCP analogs, and the OTC medication DXM. The NMDA receptor antagonist most commonly abused by adolescents in the United States is DXM. These xenobiotics cause dissociative effects by non-competitively inhibiting the action of glutamate at the NMDA receptor. Additionally, these agents modulate the actions of monoamine neurotransmitters, agonize opioid receptors, and inhibit nitric oxide synthase...
December 2015: Adolescent Medicine: State of the Art Reviews
https://www.readbyqxmd.com/read/27004392/-a-case-of-psychogenic-tremor-during-awake-craniotomy
#11
Kazumasa Kujirai, Kotoe Kamata, Toshihiro Uno, Keiko Hamada, Makoto Ozaki
A 31-year-old woman with a left frontal and parietal brain tumor underwent awake craniotomy. Propofol/remifentanil general anesthesia was induced. Following craniotomy, anesthetic administrations ceased. The level of consciousness was sufficient and she was not agitated. However, the patient complained of nausea 70 minutes into the awake phase. Considering the adverse effects of antiemetics and the upcoming surgical strategy, we did not give any medications. Nausea disappeared spontaneously while the operation was suspended...
January 2016: Masui. the Japanese Journal of Anesthesiology
https://www.readbyqxmd.com/read/26966107/a-comparison-of-subhypnotic-doses-of-propofol-and-midazolam-during-spinal-anaesthesia-for-elective-caesarean-section
#12
RANDOMIZED CONTROLLED TRIAL
Monika Danielak-Nowak, Ewa Musioł, Danuta Arct-Danielak, Izabela Duda, Karol Ludwik
BACKGROUND: This study compared two types of sedation in pregnant women receiving subarachnoid anaesthesia for elective Caesarean section. METHODS: This prospective randomised study included 56 women. Patients were sedated with propofol (PROP group, n = 27) or midazolam (MID group, n = 29) via intravenous infusion after extraction of the foetus. The following parameters were assessed at five-minute intervals: degree of sedation, heart rate, arterial pressure, ECG recording and arterial haemoglobin oxygen saturation...
2016: Anaesthesiology Intensive Therapy
https://www.readbyqxmd.com/read/26866433/impact-of-a-prophylactic-combination-of-dexamethasone-ondansetron-on-postoperative-nausea-and-vomiting-in-obese-adult-patients-undergoing-laparoscopic-sleeve-gastrectomy-during-closed-loop-propofol-remifentanil-anaesthesia-a-randomised-double-blind-placebo
#13
Aurélien Bataille, Jacques-Florian Letourneulx, Alain Charmeau, Pascale Lemedioni, Philippe Léger, Thierry Chazot, Morgan Le Guen, Pierre Diemunsch, Marc Fischler, Ngai Liu
BACKGROUND: In obese patients, the incidence of postoperative nausea and vomiting (PONV) following sleeve gastrectomy under titration of total intravenous anaesthesia (TIVA) and the relevance of risk factors to indicate prophylaxis is unknown. OBJECTIVES: The hypothesis was that after automated TIVA, prophylaxis reduces PONV following laparoscopic sleeve gastrectomy. Our objective was to determine the incidence of PONV and evaluate the efficacy of dexamethasone and ondansetron as prophylaxis when automated intravenous anaesthesia is employed...
December 2016: European Journal of Anaesthesiology
https://www.readbyqxmd.com/read/26768924/effects-of-a-novel-method-of-anesthesia-combining-propofol-and-volatile-anesthesia-on-the-incidence-of-postoperative-nausea-and-vomiting-in-patients-undergoing-laparoscopic-gynecological-surgery
#14
RANDOMIZED CONTROLLED TRIAL
Hiroaki Kawano, Naohiro Ohshita, Kimiko Katome, Takako Kadota, Michiko Kinoshita, Yayoi Matsuoka, Yasuo M Tsutsumi, Shinji Kawahito, Katsuya Tanaka, Shuzo Oshita
BACKGROUND: We investigated the effects of a novel method of anesthesia combining propofol and volatile anesthesia on the incidence of postoperative nausea and vomiting in patients undergoing laparoscopic gynecological surgery. METHODS: Patients were randomly divided into three groups: those maintained with sevoflurane (Group S, n=42), propofol (Group P, n=42), or combined propofol and sevoflurane (Group PS, n=42). We assessed complete response (no postoperative nausea and vomiting and no rescue antiemetic use), incidence of nausea and vomiting, nausea severity score, vomiting frequency, rescue antiemetic use, and postoperative pain at 2 and 24h after surgery...
January 2016: Brazilian Journal of Anesthesiology
https://www.readbyqxmd.com/read/26658268/effect-of-total-intravenous-anaesthesia-and-prophylactic-ramosetron-on-postoperative-nausea-and-vomiting-after-thyroidectomy-a-prospective-randomized-controlled-study
#15
RANDOMIZED CONTROLLED TRIAL
Han Bum Joe, Sook Young Lee, Jin-Soo Kim, Hyuk Soo Chang, Yunyong Jeong, Haewon Jeong, Sung Yong Park
OBJECTIVE: To investigate the effect of combined prophylactic ramosetron and total intravenous anaesthesia (TIVA) on postoperative nausea and vomiting (PONV), compared with sevoflurane anaesthesia without prophylactic antiemetics, in female patients undergoing thyroidectomy. METHODS: Female patients were randomized between the sevoflurane group (anaesthesia maintained with sevoflurane) or TIVA + ramosetron group (TIVAR; 0.3 mg ramosetron just before anaesthesia induction, remifentanil and propofol anaesthesia)...
February 2016: Journal of International Medical Research
https://www.readbyqxmd.com/read/26550123/efficacy-of-dexmedetomidine-on-postoperative-nausea-and-vomiting-a-meta-analysis-of-randomized-controlled-trials
#16
Xiao Liang, Miao Zhou, Jiao-Jiao Feng, Liang Wu, Shang-Ping Fang, Xin-Yu Ge, Hai-Jing Sun, Peng-Cheng Ren, Xin Lv
PURPOSE: Postoperative nausea and vomiting (PONV) is a frequent complication in postoperative period. The aim of the current meta-analysis was to assess the efficacy of dexmedetomidine on PONV. METHODS: Two researchers independently searched PubMed, Embase and Cochrane Central Register of Controlled Trials for randomized controlled trials (RCTs). The meta-analysis was performed with Review Manager. RESULTS: Eighty-two trials with 6,480 patients were included in this meta-analysis...
2015: International Journal of Clinical and Experimental Medicine
https://www.readbyqxmd.com/read/26437544/-the-interaction-of-low-dose-droperidol-propofol-and-sevoflurane-on-qtc-prolongation
#17
Tomomi Toyoda, Yoshiaki Terao, Makito Oji, Mai Okada, Hiroko Araki, Makoto Fukusaki
BACKGROUND: Droperidol is an effective antiemetic, but its use is limited because of the warning of drug-induced QT prolongation. Some reports showed that low-dose droperidol does not significantly probing QT interval. This study was aimed to determine the effect of low-dose droperidol (1.25 and 2.5 mg) on QTc interval, and the interaction among droperidol, propofol and sevoflurane. METHODS: Patients received either 1.25 mg (group L : n = 25) or 2.5 mg (group H : n = 25) droperidol, and fentanyl (3 μg x kg(-1)) was administered 2...
June 2015: Masui. the Japanese Journal of Anesthesiology
https://www.readbyqxmd.com/read/26309498/efficacy-of-dexmedetomidine-on-postoperative-nausea-and-vomiting-a-meta-analysis-of-randomized-controlled-trials
#18
Xiao Liang, Miao Zhou, Jiao-Jiao Feng, Liang Wu, Shang-Ping Fang, Xin-Yu Ge, Hai-Jing Sun, Peng-Cheng Ren, Xin Lv
PURPOSE: Postoperative nausea and vomiting (PONV) is a frequent complication in postoperative period. The aim of the current meta-analysis was to assess the efficacy of dexmedetomidine on PONV. METHODS: Two researchers independently searched PubMed, Embase and Cochrane Central Register of Controlled Trials for randomized controlled trials (RCTs). The meta-analysis was performed with Review Manager. RESULTS: Eighty-two trials with 6,480 patients were included in this meta-analysis...
2015: International Journal of Clinical and Experimental Medicine
https://www.readbyqxmd.com/read/26308518/anaesthesia-for-the-paediatric-outpatient
#19
REVIEW
Martin Jöhr, Thomas M Berger
PURPOSE OF REVIEW: The aim of this review was to discuss recent developments in paediatric anaesthesia, which are particularly relevant to the practitioner involved in paediatric outpatient anaesthesia. RECENT FINDINGS: The use of a pharmacological premedication is still a matter of debate. Several publications are focussing on nasal dexmedetomidine; however, its exact place has not yet been defined. Both inhalational and intravenous anaesthesia techniques still have their advocates; for diagnostic imaging, however, propofol is emerging as the agent of choice...
December 2015: Current Opinion in Anaesthesiology
https://www.readbyqxmd.com/read/26079533/intra-and-postoperative-low-dose-ketamine-for-adolescent-idiopathic-scoliosis-surgery-a-randomized-controlled-trial
#20
RANDOMIZED CONTROLLED TRIAL
R Minoshima, S Kosugi, D Nishimura, N Ihara, H Seki, T Yamada, K Watanabe, N Katori, S Hashiguchi, H Morisaki
BACKGROUND: In this randomized controlled trial, we examined whether intra- and postoperative infusion of low-dose ketamine decreased postoperative morphine requirement and morphine-related adverse effects as nausea and vomiting after scoliosis surgery. METHODS: After IRB approval and informed consent, 36 patients, aged 10-19 years, undergoing posterior correction surgery for adolescent idiopathic scoliosis, were randomly allocated into two groups: intra- and postoperative ketamine infusion at a rate of 2 μg/kg/min until 48 h after surgery (ketamine group, n = 17) or infusion of an equal volume of saline (placebo group, n = 19)...
November 2015: Acta Anaesthesiologica Scandinavica
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