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https://www.readbyqxmd.com/read/28930512/food-allergy
#1
Stacie M Jones, A Wesley Burks
New England Journal of Medicine, Volume 377, Issue 12, Page 1168-1176, September 2017.
September 21, 2017: New England Journal of Medicine
https://www.readbyqxmd.com/read/28929421/immunotherapy-of-food-allergy-a-comprehensive-review
#2
REVIEW
Christine Y Y Wai, Nicki Y H Leung, Patrick S C Leung, Ka Hou Chu
Food allergy imposes a severe global health burden, and thus, there is a dire need for safe and effective treatments. Allergen-specific immunotherapy (AIT) is currently the only approach to restore immune tolerance through administrating increasing doses of allergen extracts. Unfortunately, the development of AIT for food allergies has been impeded by the frequent anaphylactic side effects during the course of treatment. The emergence of component-resolved diagnosis has greatly improved our ability to identify causative allergens and revolutionized the design of AIT...
September 19, 2017: Clinical Reviews in Allergy & Immunology
https://www.readbyqxmd.com/read/28929093/the-elevated-rate-of-cesarean-section-and-its-contribution-to-non-communicable-chronic-diseases-in-latin-america-the-growing-involvement-of-the-microbiota
#3
REVIEW
Fabien Magne, Alexa Puchi Silva, Bielka Carvajal, Martin Gotteland
The current recommendation of the World Health Organization (WHO) regarding cesarean section (C-section) is that this clinical practice should be carried out only under specific conditions, when the health or life of the mother/newborn dyad is threatened, and that its use should not exceed 10-15% of the total deliveries. However, over the last few decades, the frequency of C-section delivery in medium- and high-income countries has rapidly increased worldwide. This review describes the evolution of this procedure in Latin American countries, showing that today more than half of newborns in the region are delivered by C-section...
2017: Frontiers in Pediatrics
https://www.readbyqxmd.com/read/28925766/correlation-of-types-of-food-and-asthma-diagnosis-in-childhood-a-case-control-study
#4
Souheil Hallit, Chantal Raherison, Rita Abou Abdallah, Rabih Hallit, Pascale Salameh
BACKGROUND: Studies concerning asthma in Lebanon investigated environmental and personal factors but none of them took into account the effect of nutritional habits. Our objective is to assess the effect of nutritional habits on asthma and allergies in Lebanese children aged between 3-16 years old. METHODS: This is a case-control study, conducted between December 2015 and April 2016. The Food Frequency Questionnaire was composed of 16 semi-quantitative questions covering different food categories...
September 19, 2017: Journal of Asthma: Official Journal of the Association for the Care of Asthma
https://www.readbyqxmd.com/read/28925724/pistachio-nut-allergy-an-updated-overview
#5
Joana Costa, Isa Silva, António A Vicente, M Beatriz P P Oliveira, Isabel Mafra
Pistachio nut (Pistacia vera) is highly appreciated for its organoleptic characteristics and potential health benefits. However, this tree nut is also responsible for triggering moderate to severe IgE-mediated reactions in allergic individuals. Currently, pistachio nut allergy has gained some special attention, mainly due to its intrinsic relation with cashew nut allergy. Like for other nuts, the prevalence of pistachio nut allergy seems to be increasing at a global scale. Until now, there are five allergenic proteins officially listed for pistachio nut (Pis v 1, Pis v 2, Pis v 3, Pis v 4 and Pis v 5)...
September 19, 2017: Critical Reviews in Food Science and Nutrition
https://www.readbyqxmd.com/read/28925556/national-allergy-programme-had-little-impact-on-parent-reported-food-allergies-in-children-aged-6-7-years
#6
Sauli Palmu, Paula Heikkilä, Virpi Uski, Siina Niitty, Sari Kurikka, Matti Korppi
AIM: The ten-year Finnish national allergy programme was launched in 2008 to lessen the disease and psychological burden of allergy. This study assessed the prevalence of parent-reported food allergies requiring avoidance diets at primary school in children aged six and seven years. METHODS: The cohort comprised 1,937 children (51% boys) who started primary school in Tampere, Finland in August 2016. School health nurses charted parent-reported, doctor-diagnosed food allergies requiring avoidance diets as part of the routine health examination...
September 19, 2017: Acta Paediatrica
https://www.readbyqxmd.com/read/28925060/current-food-allergenic-risk-assessment-is-it-fit-for-novel-foods-status-quo-and-identification-of-gaps
#7
REVIEW
Gabriel Mazzucchelli, Thomas Holzhauser, Tanja Cirkovic-Velickovic, Araceli Diaz-Perales, Elena Molina, Paola Roncada, Pedro Rodrigues, Kitty Verhoeckx, Karin Hoffmann-Sommergruber
Food allergies are recognised as a global health concern. In order to protect allergic consumers from severe symptoms, allergenic risk assessment for well known foods and foods containing genetically modified ingredients was installed. However, population is steadily growing and there is a rising need to provide adequate protein-based foods, including novel sources, not yet used for human consumption. In this context safety issues such as a potential increased allergenic risk need to be assessed before marketing novel food sources...
September 19, 2017: Molecular Nutrition & Food Research
https://www.readbyqxmd.com/read/28924447/passive-blood-anaphylaxis-subcutaneous-immunoglobulins-are-a-cause-of-ongoing-passive-anaphylactic-reaction
#8
Przemyslaw Zdziarski, Andrzej Gamian, Jacek Majda, Agnieszka Korzeniowska-Kowal
BACKGROUND: Allergic, especially anaphylactic, reactions during immunoglobulin replacement therapy are rare, but their pathophysiology and classification remain ambiguous. Recent findings show positive results of skin tests with commercially available immunoglobulins, but target antigens and responsible compounds of the tested immunoglobulins have not been strictly identified. CASE DESCRIPTION AND FINDINGS: Four adult patients with recently diagnosed common variable immunodeficiency qualified for standard subcutaneous immunoglobulin replacement therapy regimen...
2017: Allergy, Asthma, and Clinical Immunology
https://www.readbyqxmd.com/read/28922259/gastrointestinal-symptoms-of-food-challenge-proven-non-ige-cow-s-milk-allergy-are-dissipated-by-early-school-age
#9
Noora Helin, Kaija-Leena Kolho, Erik Qvist, Mika Mäkelä, Laura Merras-Salmio
OBJECTIVES: To evaluate the current well-being and dietary restrictions in children six years after food challenge confirmed diagnosis of non-IgE cow's milk protein allergy, compared to peers with gastrointestinal symptoms but negative food challenge. To evaluate the diagnostic process retrospectively. METHODS: Internet-based survey for mothers whose children underwent six years ago the double-blind, placebo-controlled food challenge for cow's milk because of gastrointestinal symptoms causing suspicion of non-IgE cow's milk protein allergy...
September 16, 2017: Journal of Pediatric Gastroenterology and Nutrition
https://www.readbyqxmd.com/read/28921896/evaluating-potential-risks-of-food-allergy-and-toxicity-of-soy-leghemoglobin-expressed-in-pichia-pastoris
#10
Yuan Jin, Xiaoyun He, Kwame Andoh-Kumi, Rachel Z Fraser, Mei Lu, Richard E Goodman
SCOPE: The Soybean (Glycine max) leghemoglobin c2 (LegHb) gene was introduced into Pichia pastoris yeast for sustainable production of a heme-carrying protein, for organoleptic use in plant-based meat. The potential allergenicity and toxicity of LegHb and 17 Pichia host-proteins each representing ≥1% of total protein in production batches were evaluated by literature review, bioinformatics sequence comparisons to known allergens or toxins, and in vitro pepsin digestion. METHODS AND RESULTS: Literature searches found no evidence of allergenicity or toxicity for these proteins...
September 18, 2017: Molecular Nutrition & Food Research
https://www.readbyqxmd.com/read/28917235/reconfirmation-of-improved-tolerance-to-a-new-amino-acid-based-formula-by-infants-with-cow-s-milk-protein-allergy
#11
Pipop Jirapinyo, Narumon Densupsoontorn, Channagan Kangwanpornsiri, Renu Wongarn, Hathaichanok Tirapongporn, Kwanjai Chotipanang, Phakkanan Phuangphan
BACKGROUND AND OBJECTIVES: Reasons for intolerance to commercial amino acid-based formulas (cAAF) in infants diagnosed with cow's milk protein allergy (CMA) remain unknown. We assume that minute amounts of proteins, presenting in the glucose polymers derived from corn starch (cGPs), can elicit the intolerance to the cAAFs observed in some infants with CMA. By replacing cGPs with glucose polymers derived from rice starch (rGPs), a new amino acid-based (nAAF) formula has been shown to be better tolerated than an existing cAAF...
2017: Asia Pacific Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/28916424/predictors-of-epinephrine-dispensing-and-allergy-follow-up-after-emergency-department-visit-for-anaphylaxis
#12
Megan Motosue, M Fernanda Bellolio, Holly K Van Houten, Nilay D Shah, Ronna L Campbell
BACKGROUND: National guidelines recommend that patients with anaphylaxis be prescribed an epinephrine auto-injector (EAI) and referred to an allergy/immunology (A/I) specialist. OBJECTIVE: To evaluate guideline concordance and identify predictors of EAI dispensing and A/I follow-up in patients with anaphylaxis treated in the emergency department (ED). METHODS: We identified patients seen in the ED for anaphylaxis from 2010 through 2014 from an administrative claims database using an expanded International Classification of Diseases, Ninth Revision, Clinical Modification diagnosis code algorithm...
September 12, 2017: Annals of Allergy, Asthma & Immunology
https://www.readbyqxmd.com/read/28914636/dietary-intervention-for-preventing-food-allergy-in-children
#13
Yichao Wang, Katrina J Allen, Jennifer J Koplin
PURPOSE OF REVIEW: In the past decade, food allergy has been increasingly recognized as an important public health issue. The role of maternal and infant diet in the development of food allergy has been a major focus of research throughout this period. Recently, research in this area has moved from observational studies to intervention trials, and the findings from these trials have started to influence infant feeding guidelines. In this article, we review recent studies of dietary interventions for preventing food allergy, summarize current knowledge and discuss future research directions...
September 13, 2017: Current Opinion in Pediatrics
https://www.readbyqxmd.com/read/28913993/a-retrospective-study-of-korean-adults-with-food-allergy-differences-in-phenotypes-and-causes
#14
So Hee Lee, Ga Young Ban, Kyunguk Jeong, Yoo Seob Shin, Hae Sim Park, Sooyoung Lee, Young Min Ye
PURPOSE: Increasing in prevalence, food allergy (FA) is becoming an important public health concern. In Korean adults, however, clinical phenotypes and causes of FA have not been studied. We aimed to study common causative allergens and clinical manifestations of FA in Korean adults. METHODS: This study was conducted as a retrospective review of medical records for 95 patients (≥19 years old) diagnosed with FA from September 2014 to August 2015 at a single university hospital...
November 2017: Allergy, Asthma & Immunology Research
https://www.readbyqxmd.com/read/28906157/economic-factors-impacting-food-allergen-management-perspectives-from-the-food-industry
#15
Ruchi S Gupta, Steve L Taylor, Joseph L Baumert, Lauren M Kao, Erik Schuster, Bridget M Smith
Food allergies affect up to 8% of children in the United States and may occasionally lead to severe life-threatening reactions. Because there is currently no cure for food allergies, strict avoidance of the allergen-containing foods is the only means of preventing an allergic reaction. Consumers rely on food manufacturers to reliably track and declare the presence of food allergens in products. Over the past 10 to 20 years, the food industry has increasingly adopted allergen control approaches in its processing facilities...
September 14, 2017: Journal of Food Protection
https://www.readbyqxmd.com/read/28906044/specific-ige-to-peanut-2s-albumin-ara-h-7-has-a-discriminative-ability-comparable-to-ara-h-2-and-6
#16
Mark A Blankestijn, Henny G Otten, Waltraud Suer, Alf Weimann, Edward F Knol, André C Knulst
BACKGROUND: Little is known on the clinical relevance of peanut 2S albumin Ara h 7. OBJECTIVE: To investigate the discriminative ability of Ara h 7 in peanut allergy and assess the role of cross-reactivity between Ara h 2, 6 and Ara h 7 isoforms. METHODS: Sensitization to recombinant peanut storage proteins Ara h 1, 2, 3, 6 and 7 was assessed using a line blot in sera from 40 peanut tolerant and 40 peanut allergic patients, based on food challenge outcome...
September 14, 2017: Clinical and Experimental Allergy: Journal of the British Society for Allergy and Clinical Immunology
https://www.readbyqxmd.com/read/28904968/the-prevalence-of-ocular-allergy-and-comorbidities-in-chinese-school-children-in-shanghai
#17
Yanqing Feng, Xiangning Wang, Fang Wang, Rongming Liu, Lu Chen, Shuqin Wu, Xia Yang, Miaoying Chen, Yu-Qing Rao, Jing Li
OBJECTIVE: To investigate the prevalence and features of ocular allergy (OA) and comorbidities among school children in Shanghai, China. METHODS: This was a population-based cross-sectional study. Each participant completed an ISAAC-based questionnaire. The prevalence of OA symptoms, allergic rhinitis (AR) asthma, atopic dermatitis (AD), and sensitization to mites, pollen, and food was analyzed. RESULTS: A total of 724 and 942 completed questionnaires from the 7-9-year-old (young group) and the 12-14-year-old (teen group) groups were analyzed, respectively...
2017: BioMed Research International
https://www.readbyqxmd.com/read/28904734/a-17-year-old-male-with-a-small-bowel-neuroendocrine-tumor-flushing-differential-diagnosis
#18
Maria Alejandra Forero Molina, Elizabeth Garcia, Deyanira Gonzalez-Devia, Rafael García-Duperly, Alonso Vera
BACKGROUND: Neuroendocrine tumors (NETs) are heterogeneous neoplasms that originate from cells with a secretory function. Small bowel NETs (SB-NETs) are related to serotonin hypersecretion which causes: flushing, diarrhea, abdominal pain, bronchoconstriction and heart involvement, also known as carcinoid syndrome (CS). CS can be confused with an allergic reaction and thus should be considered as a differential diagnosis in the allergy consult. We present the case of a pediatric patient initially referred under the suspicion of food allergies...
2017: World Allergy Organization Journal
https://www.readbyqxmd.com/read/28903469/signatures-in-the-gut-microbiota-of-japanese-infants-who-developed-food-allergies-in-early-childhood
#19
Masaru Tanaka, Yuki Korenori, Masakazu Washio, Takako Kobayashi, Rie Momoda, Chikako Kiyohara, Aki Kuroda, Yuka Saito, Kenji Sonomoto, Jiro Nakayama
Bacterial colonization in infancy is considered crucial for the development of the immune system. Recently, there has been a drastic increase in childhood allergies in Japan. Therefore, we conducted a prospective study with 56 infants on the relationship between gut microbiota in the first year of life and the development of allergies during the first 3 years. In the lactation period, organic acid producers such as Leuconostoc, Weissella and Veillonella tended to be underrepresented in subjects who developed food allergies (FA, n = 14) within the first two years...
August 1, 2017: FEMS Microbiology Ecology
https://www.readbyqxmd.com/read/28900324/a-significant-breakthrough-in-the-incidence-of-childhood-cancers-and-evaluation-of-its-risk-factors-in-southern-iran
#20
Asma Erjaee, Maryam Niknam, Ahmadreza Sadeghi, Maryam Dehghani, Zeinab Safaei, Saeed Hosseini Teshnizi, Mehran Karimi
BACKGROUND AND OBJECTIVE: This study investigates epidemiologic and practical information about the incidence and risk factors of childhood cancer in a population of Southern Iranian children. MATERIALS AND METHODS: A total number of 300 cancer patients along with 600 age- and gender-matched healthy control were interviewed by a trained physician regarding their demographic characteristics, and major family-associated risk factors, childhood malignancies. RESULTS: The average annual percentage change for cancers in the studied population is calculated as 45%...
April 2017: Indian Journal of Medical and Paediatric Oncology
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