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https://www.readbyqxmd.com/read/29153564/sex-dimorphism-in-the-myocardial-response-to-aortic-stenosis
#1
Thomas A Treibel, Rebecca Kozor, Marianna Fontana, Camilla Torlasco, Patricia Reant, Sveeta Badiani, Maria Espinoza, John Yap, Javier Diez, Alun D Hughes, Guy Lloyd, James C Moon
OBJECTIVES: The goal of this study was to explore sex differences in myocardial remodeling in aortic stenosis (AS) by using echocardiography, cardiac magnetic resonance (CMR), and biomarkers. BACKGROUND: AS is a disease of both valve and left ventricle (LV). Sex differences in LV remodeling are reported in AS and may play a role in disease phenotyping. METHODS: This study was a prospective assessment of patients awaiting surgical valve replacement for severe AS using echocardiography, the 6-min walking test, biomarkers (high-sensitivity troponin T and N-terminal pro-brain natriuretic peptide), and CMR with late gadolinium enhancement and extracellular volume fraction, which dichotomizes the myocardium into matrix and cell volumes...
November 10, 2017: JACC. Cardiovascular Imaging
https://www.readbyqxmd.com/read/29121956/regional-differences-in-prognostic-value-of-cardiac-valve-plane-displacement-in-systemic-light-chain-amyloidosis
#2
Marco M Ochs, Thomas Fritz, Nisha Arenja, Johannes Riffel, Florian Andre, Derliz Mereles, Fabian Aus dem Siepen, Ute Hegenbart, Stefan Schönland, Hugo A Katus, Matthias G W Friedrich, Sebastian J Buss
BACKGROUND: To compare the prognostic value of cardiac valve plane displacement (CVPD) on various locations in cardiac light chain (AL) amyloidosis. METHODS: Consecutive patients with biopsy-proven cardiac involvement in AL amyloidosis who had undergone cardiovascular magnetic resonance (CMR) between 2005 and 2014 in our institution, were retrospectively identified and data analyzed. The primary combined endpoint was all-cause mortality or heart transplantation...
November 9, 2017: Journal of Cardiovascular Magnetic Resonance
https://www.readbyqxmd.com/read/29119274/quantification-of-pulmonary-regurgitation-and-prediction-of-pulmonary-valve-replacement-by-echocardiography-in-patients-with-congenital-heart-defects-in-comparison-to-cardiac-magnetic-resonance-imaging
#3
Claudia Dellas, Laura Kammerer, Verena Gravenhorst, Joachim Lotz, Thomas Paul, Michael Steinmetz
Pulmonary regurgitation (PR) is common in patients with congenital heart defects (CHD) and contributes to morbidity and mortality in the long-term. We investigated in this retrospective analysis whether readily accessible echocardiographic parameters are useful for quantification of PR and for predicting pulmonary valve replacement (PVR) in comparison to the gold-standard phase contrast (PC) flow measurements from cardiovascular magnetic resonance (CMR). Continuous wave (CW) Doppler and colour flow images in echocardiograms from 53 patients with CHD were analysed...
November 8, 2017: International Journal of Cardiovascular Imaging
https://www.readbyqxmd.com/read/29119025/parachute-like-mitral-valve-tuberculoma-a-rare-presentation
#4
Arslan Masood, Gul Zaman Khan, Irfan Bashir, Zubair Akram
There have been anecdotal reports of tuberculous cardiac involvement, mainly in cases of military tuberculosis or immune deficient individuals. The spectrum of clinical presentations of tuberculous cardiac involvements includes incidental detection of single and multiple well-circumscribed tuberculomas, symptomatic obstructive lesions, AV conduction abnormalities, and even sudden death. We present a case of cardiac tuberculoma in an immune-competent person who presented with worsening dyspnea. The unique morphology of this mass posed an imaging challenge that required 4-dimensional (4D) echocardiography and cardiac magnetic resonance (CMR) detail to differentiate the mass from an anterior mitral leaflet (AML) aneurysm...
2017: Case Reports in Cardiology
https://www.readbyqxmd.com/read/29092127/iatrogenic-lutembacher-syndrome-after-percutaneous-mitral-commissurotomy
#5
Theodoros D Karamitsos, Chrysovalantou Nikolaidou, Athanasios Koutsakis, Kyriakos Anastasiadis, Charalambos Karvounis, Stavros Hadjimiltiades
Atrial septal defects (ASDs) are common immediately after percutaneous mitral commissurotomy (PMC). They are usually small, hemodynamically insignificant, and tend to decrease or disappear within 6 to 12 months. Herein, a case is described of persistent ASD in a patient with mitral valve stenosis who had undergone successful PMC three years previously. The patient had signs and symptoms of right heart failure and severe tricuspid regurgitation (TR) with borderline right ventricular systolic function on echocardiography, in addition to the ASD...
May 2017: Journal of Heart Valve Disease
https://www.readbyqxmd.com/read/29064540/myocardial-strain-characteristics-and-outcomes-after-transcatheter-aortic-valve-replacement
#6
Dominik Buckert, Raid Tibi, Maciej Cieslik, Michael Radermacher, Yang-Yang Qu, Volker Rasche, Peter Bernhardt, Vinzenz Hombach, Wolfgang Rottbauer, Jochen Wöhrle
BACKGROUND: Objective of this study was to make an assessment of standard functional and deformation parameters (strain) in patients after transcatheter aortic valve replacement (TAVR) by cardiac magnetic resonance imaging (CMR) and the evaluation of their prognostic impact. METHODS: Patients undergoing TAVR received CMR on a 1.5T whole-body scanner at 3 months after the procedure. Deformation parameters (strain, strain rate, velocity, displacement) were assessed in longitudinal, circumferential and radial orientation using a feature tracking approach...
October 24, 2017: Cardiology Journal
https://www.readbyqxmd.com/read/29061184/assessment-of-reverse-remodeling-predicted-by-myocardial-deformation-on-tissue-tracking-in-patients-with-severe-aortic-stenosis-a-cardiovascular-magnetic-resonance-imaging-study
#7
Ji-Won Hwang, Sung Mok Kim, Sung-Ji Park, Eun Jeong Cho, Eun Kyoung Kim, Sung-A Chang, Sang-Chol Lee, Yeon Hyeon Choe, Seung Woo Park
BACKGROUND: The technique of tissue tracking with balanced steady-state free precession cine sequences was introduced, and allowed myocardial strain to be derived directly, offering advantages over traditional myocardial tagging. The aim of this study was to evaluate the correlation between reverse remodeling as an outcome and left ventricular strain using cardiovascular magnetic resonance imaging (CMR) tissue tracking, and to evaluate prediction of reverse remodeling by myocardial deformation in patients with severe aortic stenosis (AS)...
October 23, 2017: Journal of Cardiovascular Magnetic Resonance
https://www.readbyqxmd.com/read/29059484/imaging-characteristics-of-papillary-muscle-site-of-origin-of-ventricular-arrhythmias-in-patients-with-mitral-valve-prolapse
#8
Brian L Fulton, Jackson J Liang, Andres Enriquez, Fermin C Garcia, Gregory E Supple, Michael P Riley, Robert D Schaller, Sanjay Dixit, David J Callans, Francis E Marchlinski, Yuchi Han
BACKGROUND: Mitral valve prolapse has been associated with increased risk of ventricular arrhythmias. We aimed to examine whether certain cardiac imaging characteristics are associated with papillary muscle origin of ventricular arrhythmias in these patients. METHODS AND RESULTS: We screened electronic medical records of all patients documented to have mitral valve prolapse on either transthoracic echocardiogram (TTE) or cardiac magnetic resonance imaging (CMR) in our center, who also underwent an electrophysiologic study (EPS) between 2007 and 2016...
October 23, 2017: Journal of Cardiovascular Electrophysiology
https://www.readbyqxmd.com/read/29027633/multi-modality-imaging-in-the-evaluation-and-treatment-of-mitral-regurgitation
#9
REVIEW
Marc-André Bouchard, Claudia Côté-Laroche, Jonathan Beaudoin
Mitral regurgitation (MR) is frequent and associated with increased mortality and morbidity when severe. It may be caused by intrinsic valvular disease (primary MR) or ventricular deformation (secondary MR). Imaging has a critical role to document the severity, mechanism, and impact of MR on heart function as selected patients with MR may benefit from surgery whereas other will not. In patients planned for a surgical intervention, imaging is also important to select candidates for mitral valve (MV) repair over replacement and to predict surgical success...
October 13, 2017: Current Treatment Options in Cardiovascular Medicine
https://www.readbyqxmd.com/read/29020257/reappraising-myocardial-fibrosis-in-severe-aortic-stenosis-an-invasive-and-non-invasive-study-in-133-patients
#10
Thomas A Treibel, Begoña López, Arantxa González, Katia Menacho, Rebecca S Schofield, Susana Ravassa, Marianna Fontana, Steven K White, Carmelo DiSalvo, Neil Roberts, Michael T Ashworth, Javier Díez, James C Moon
Aims: To investigate myocardial fibrosis (MF) in a large series of severe aortic stenosis (AS) patients using invasive biopsy and non-invasive imaging. Methods and results: One hundred thirty-three patients with severe, symptomatic AS accepted for surgical aortic valve replacement underwent cardiovascular magnetic resonance (CMR) with late gadolinium enhancement (LGE) and extracellular volume fraction (ECV) quantification. Intra-operative left ventricular (LV) biopsies were performed by needle or scalpel, yielding tissue with (n = 53) and without endocardium (n = 80), and compared with 10 controls...
July 22, 2017: European Heart Journal
https://www.readbyqxmd.com/read/28988308/improving-the-role-of-echocardiography-in-studying-the-right-ventricle-of-repaired-tetralogy-of-fallot-patients-comparison-with-cardiac-magnetic-resonance
#11
Carolina D'Anna, Armando Caputi, Benedetta Natali, Benedetta Leonardi, Aurelio Secinaro, Gabriele Rinelli, Alessia Del Pasqua, Claudia Esposito, Adriano Carotti, Fabrizio Drago, Marcello Chinali
Right ventricular (RV) evaluation represents one of the major clinical tasks in the follow-up of repaired tetralogy of Fallot patients (rToF) with pulmonary valve regurgitation, as both severe RV dilatation and dysfunction are key factors in defining the need of pulmonary valve replacement. The aim of our study was to report the diagnostic accuracy of echocardiography in the identification of rToF patients with severely dilated and/or depressed RV as compared to cardiac magnetic resonance (CMR). Among our patients with rToF, a subgroup of 95 (17...
October 7, 2017: International Journal of Cardiovascular Imaging
https://www.readbyqxmd.com/read/28822982/evaluation-of-aortic-regurgitation-with-cardiac-magnetic-resonance-imaging-a-systematic-review
#12
REVIEW
James C Lee, Kelley R Branch, Christian Hamilton-Craig, Eric V Krieger
This review summaries the utility, application and data supporting use of cardiac magnetic resonance imaging (CMR) to evaluate and quantitate aortic regurgitation. We systematically searched Medline and PubMed for original research articles published since 2000 that provided data on the quantitation of aortic regurgitation by CMR and identified 11 articles for review. Direct aortic measurements using phase contrast allow quantitation of volumetric flow across the aortic valve and are highly reproducible and accurate compared with echocardiography...
August 19, 2017: Heart: Official Journal of the British Cardiac Society
https://www.readbyqxmd.com/read/28808772/longitudinal-strain-assessed-by-cardiac-magnetic-resonance-correlates-to-hemodynamic-findings-in-patients-with-severe-aortic-stenosis-and-predicts-positive-remodeling-after-transcatheter-aortic-valve-replacement
#13
Dominik Buckert, Maciej Cieslik, Raid Tibi, Michael Radermacher, Volker Rasche, Peter Bernhardt, Vinzenz Hombach, Wolfgang Rottbauer, Jochen Wöhrle
AIMS: To assess left-ventricular strain parameters before and after transcatheter aortic valve replacement (TAVR) by feature tracking cardiac magnetic resonance imaging (FT CMR) and to correlate the findings to hemodynamic state and left-ventricular remodeling. METHODS AND RESULTS: Patients with symptomatic AS underwent FT CMR before and after TAVR. Patients were carefully evaluated by a comprehensive work-up including CMR, echocardiography and left and right heart catheterization...
August 14, 2017: Clinical Research in Cardiology: Official Journal of the German Cardiac Society
https://www.readbyqxmd.com/read/28802508/prognostic-significance-of-left-ventricular-fibrosis-in-patients-with-congenital-bicuspid-aortic-valve
#14
Gentian Lluri, Pierangelo Renella, J Paul Finn, Gabriel Vorobiof, Jamil Aboulhosn, Arjun Deb
This study sought to evaluate the prognostic value of left ventricular (LV) fibrosis assessed by late gadolinium enhancement (LGE) of the myocardium during cardiac magnetic resonance (CMR) imaging in patients with bicuspid aortic valve (BAV), which is associated with early aortic valve fibrosis and calcification. To what degree the LV myocardial wall is affected by fibrosis and its prognostic value is currently unknown. This is a retrospective, single-center study evaluating all adult patients with BAV who had CMR and followed from March 2002 to March 2016...
October 1, 2017: American Journal of Cardiology
https://www.readbyqxmd.com/read/28776135/importance-of-non-invasive-right-and-left-ventricular%C3%A2-variables-on-exercise-capacity-in-patients-with-tetralogy-of-fallot-hemodynamics
#15
Christian Meierhofer, Timon Tavakkoli, Andreas Kühn, Kurt Ulm, Alfred Hager, Jan Müller, Stefan Martinoff, Peter Ewert, Heiko Stern
Good quality of life correlates with a good exercise capacity in daily life in patients with tetralogy of Fallot (ToF). Patients after correction of ToF usually develop residual defects such as pulmonary regurgitation or stenosis of variable severity. However, the importance of different hemodynamic parameters and their impact on exercise capacity is unclear. We investigated several hemodynamic parameters measured by cardiovascular magnetic resonance (CMR) and echocardiography and evaluated which parameter has the most pronounced effect on maximal exercise capacity determined by cardiopulmonary exercise testing (CPET)...
December 2017: Pediatric Cardiology
https://www.readbyqxmd.com/read/28764576/contemporary-evaluation-of-mitral-regurgitation-3d-echocardiography-cardiac-magnetic-resonance-and-procedural-planning
#16
Frank E Corrigan, Aneel Maini, Shawn Reginauld, Stamatios Lerakis
Mitral regurgitation is one of the more common forms of valvular heart disease. Given the expansion of therapies for structural heart disease, new therapies for mitral regurgitation are emerging. An accurate description and classification of mitral disease is important to understand pathology and provide recommendations for therapy. Areas covered: In the modern evaluation of mitral regurgitation, 3-dimensional echocardiography (3DE) and cardiac magnetic resonance imaging (CMR) play important roles which overcome the prior limitations of 2-dimensional echocardiography...
September 2017: Expert Review of Cardiovascular Therapy
https://www.readbyqxmd.com/read/28750632/impact-of-bileaflet-mitral-valve-prolapse-on-quantification-of-mitral-regurgitation-with-cardiac-magnetic-resonance-a-single-center-study
#17
Gabriella Vincenti, Pier Giorgio Masci, Tobias Rutz, Jonathan De Blois, Milan Prša, Xavier Jeanrenaud, Juerg Schwitter, Pierre Monney
BACKGROUND: To quantify mitral regurgitation (MR) with CMR, the regurgitant volume can be calculated as the difference between the left ventricular (LV) stroke volume (SV) measured with the Simpson's method and the reference SV, i.e. the right ventricular SV (RVSV) in patients without tricuspid regurgitation. However, for patients with prominent mitral valve prolapse (MVP), the Simpson's method may underestimate the LV end-systolic volume (LVESV) as it only considers the volume located between the apex and the mitral annulus, and neglects the ventricular volume that is displaced into the left atrium but contained within the prolapsed mitral leaflets at end systole...
July 27, 2017: Journal of Cardiovascular Magnetic Resonance
https://www.readbyqxmd.com/read/28728865/mass-spring-models-for-the-simulation-of-mitral-valve-function-looking-for-a-trade-off-between-reliability-and-time-efficiency
#18
O A Pappalardo, F Sturla, F Onorati, G Puppini, M Selmi, G B Luciani, G Faggian, A Redaelli, E Votta
Patient-specific finite element (FE) models can assess the impact of mitral valve (MV) repair on the complex MV anatomy and function. However, FE excessive time requirements hamper their use for surgical planning; mass-spring models (MSMs) represent a more approximate approach but can provide almost real-time simulations. On this basis, we implemented MSMs of three healthy MVs from cardiac magnetic resonance (cMR) imaging to simulate the systolic MV closure, including the in vivo papillary muscles and annular kinematics, and the anisotropic and non-linear mechanical response of MV tissues...
July 17, 2017: Medical Engineering & Physics
https://www.readbyqxmd.com/read/28694784/4d-flow-analysis-of-bav-related-fluid-dynamic-alterations-evidences-of-wall-shear-stress-alterations-in-absence-of-clinically-relevant-aortic-anatomical-remodeling
#19
Filippo Piatti, Francesco Sturla, Malenka M Bissell, Selene Pirola, Massimo Lombardi, Igor Nesteruk, Alessandro Della Corte, Alberto C L Redaelli, Emiliano Votta
Bicuspid aortic valve (BAV) is the most common congenital cardiac disease and is a foremost risk factor for aortopathies. Despite the genetic basis of BAV and of the associated aortopathies, BAV-related alterations in aortic fluid-dynamics, and particularly in wall shear stresses (WSSs), likely play a role in the progression of aortopathy, and may contribute to its pathogenesis. To test whether WSS may trigger aortopathy, in this study we used 4D Flow sequences of phase-contrast cardiac magnetic resonance imaging (CMR) to quantitatively compare the in vivo fluid dynamics in the thoracic aorta of two groups of subjects: (i) five prospectively enrolled young patients with normo-functional BAV and with no aortic dilation and (ii) ten age-matched healthy volunteers...
2017: Frontiers in Physiology
https://www.readbyqxmd.com/read/28684436/major-adverse-events-and-atrial-tachycardia-in-ebstein-s-anomaly-predicted-by-cardiovascular-magnetic-resonance
#20
Riikka Rydman, Yumi Shiina, Gerhard-Paul Diller, Koichiro Niwa, Wei Li, Hideki Uemura, Anselm Uebing, Umberto Barbero, Beatriz Bouzas, Sabine Ernst, Tom Wong, Dudley J Pennell, Michael A Gatzoulis, Sonya V Babu-Narayan
OBJECTIVES: Patients with Ebstein's anomaly of the tricuspid valve (EA) are at risk of tachyarrhythmia, congestive heart failure and sudden cardiac death. We sought to determine the value of cardiovascular magnetic resonance (CMR) for predicting these outcomes. METHODS: Seventy-nine consecutive adult patients (aged 37±15 years) with unrepaired EA underwent CMR and were followed prospectively for a median 3.4 (range 0.4-10.9) years for clinical outcomes, namely major adverse cardiovascular events (MACEs: sustained ventricular tachycardia/heart failure hospital admission/cardiac transplantation/death) and first-onset atrial tachyarrhythmia (AT)...
July 6, 2017: Heart: Official Journal of the British Cardiac Society
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