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https://www.readbyqxmd.com/read/28642994/cardiovascular-magnetic-resonance-imaging-to-assess-myocardial-fibrosis-in-valvular-heart-disease
#1
Tomaz Podlesnikar, Victoria Delgado, Jeroen J Bax
The left ventricular (LV) remodeling process associated with significant valvular heart disease (VHD) is characterized by an increase of myocardial interstitial space with deposition of collagen and loss of myofibers. These changes occur before LV systolic function deteriorates or the patient develops symptoms. Cardiovascular magnetic resonance (CMR) permits assessment of reactive fibrosis, with the use of T1 mapping techniques, and replacement fibrosis, with the use of late gadolinium contrast enhancement...
June 22, 2017: International Journal of Cardiovascular Imaging
https://www.readbyqxmd.com/read/28639972/imaging-in-repaired-tetralogy-of-fallot-with-a-focus-on-recent-advances-in-echocardiography
#2
Guillermo Larios, Mark K Friedberg
PURPOSE OF REVIEW: Imaging is essential for the management of adults with repaired tetralogy of Fallot (rToF). Echocardiography and cardiac magnetic resonance imaging are the central modalities to assess rToF. Here we review recent literature on imaging rToF, focusing on echocardiography and advances in assessment of cardiac mechanics. RECENT FINDINGS: Several two-dimensional, three-dimensional, and Doppler echo parameters have been proposed to assess pulmonary regurgitation, right ventricular volumes and ejection fraction, but most of them still have important limitations in their feasibility and reliability compared to cardiac magnetic resonance (CMR)...
July 20, 2017: Current Opinion in Cardiology
https://www.readbyqxmd.com/read/28575228/right-ventricular-outflow-tract-dimensions-in-arrhythmogenic-right-ventricular-cardiomyopathy-dysplasia-a-multicentre-study-comparing-echocardiography-and-cardiovascular-magnetic-resonance
#3
Alexander Gotschy, Ardan M Saguner, Markus Niemann, Sandra Hamada, Deniz Akdis, Ji-Na Yoon, Elena V Parmon, Victoria Delgado, Jeroen J Bax, Sebastian Kozerke, Corinna Brunckhorst, Firat Duru, Felix C Tanner, Robert Manka
Aims: Right ventricular outflow tract (RVOT) dilation is one of the echocardiographic criteria in the 2010 revised Task Force Criteria (TFC) of arrhythmogenic right ventricular cardiomyopathy/dysplasia (ARVC/D). However, studies comparing cardiac magnetic resonance (CMR) and transthoracic echocardiography (TTE) suggest a lower diagnostic accuracy of TTE due to its operator dependence and limited reproducibility. The goal of this study was to compare the 2010 TFC measures of RVOT dilation with three alternative measures for improving the echocardiographic assessment of RVOT in patients with ARVC/D...
May 26, 2017: European Heart Journal Cardiovascular Imaging
https://www.readbyqxmd.com/read/28570260/comparison-of-non-contrast-cardiovascular-magnetic-resonance-imaging-to-computed-tomography-angiography-for-aortic-annular-sizing-before-transcatheter-aortic-valve-replacement
#4
Jing Wang, Dinesh H Jagasia, Yamuna R Kondapally, Howard C Herrmann, Yuchi Han
BACKGROUND: Accurate measurement of aortic annulus is crucial before transcatheter aortic valve replacement (TAVR). Computed tomography (CT) angiography is the most commonly utilized method, but requires contrast administration. Cardiovascular magnetic resonance (CMR) imaging is a promising alternative modality to provide aortic annulus measurements. Few studies have compared the clinical feasibility and accuracy of non-contrast CMR to contrast-enhanced computed tomography (CT) angiography in order to provide a non-contrast alternative to CT annular sizing...
May 15, 2017: Journal of Invasive Cardiology
https://www.readbyqxmd.com/read/28540067/utility-of-cardiac-magnetic-resonance-for-evaluation-of-mitral-regurgitation-prior-to-mitral-valve-surgery
#5
REVIEW
Neil K Mehta, Jiwon Kim, Jonathan Y Siden, Sara Rodriguez-Diego, Javid Alakbarli, Antonino Di Franco, Jonathan W Weinsaft
Mitral regurgitation (MR) is a common cause of morbidity worldwide and an accepted indication for interventional therapies which aim to reduce or resolve adverse clinical outcomes associated with MR. Cardiac magnetic resonance (CMR) provides highly accurate means of assessing MR, including a variety of approaches that can measure MR based on quantitative flow. Additionally, CMR is widely accepted as a reference standard for cardiac chamber quantification, enabling reliable detection of subtle changes in cardiac chamber size and function so as to guide decision-making regarding timing of mitral valve directed therapies...
April 2017: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/28540066/cine-cmr-partial-voxel-segmentation-demonstrates-increased-aortic-stiffness-among-patients-with-marfan-syndrome
#6
Parmanand Singh, Zaid Almarzooq, Noel C F Codell, Yi Wang, Mary J Roman, Richard B Devereux, Jonathan W Weinsaft
BACKGROUND: Standard cine-cardiac magnetic resonance (CMR) imaging is commonly used to evaluate cardiac structure, geometry and function. Prior studies have shown that automated segmentation via partial voxel interpolation (PVI) accurately quantifies phantom-based cardiac chamber volumes and necropsy left ventricular myocardial mass. Despite this, the applicability and usefulness of PVI in the determination of physiologic parameters of the aorta such as aortic stiffness has yet to be investigated...
April 2017: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/28540065/dynamic-and-quantitative-evaluation-of-degenerative-mitral-valve-disease-a-dedicated-framework-based-on-cardiac-magnetic-resonance-imaging
#7
Francesco Sturla, Francesco Onorati, Giovanni Puppini, Omar A Pappalardo, Matteo Selmi, Emiliano Votta, Giuseppe Faggian, Alberto Redaelli
BACKGROUND: Accurate quantification of mitral valve (MV) morphology and dynamic behavior over the cardiac cycle is crucial to understand the mechanisms of degenerative MV dysfunction and to guide the surgical intervention. Cardiac magnetic resonance (CMR) imaging has progressively been adopted to evaluate MV pathophysiology, although a dedicated framework is required to perform a quantitative assessment of the functional MV anatomy. METHODS: We investigated MV dynamic behavior in subjects with normal MV anatomy (n=10) and patients referred to surgery due to degenerative MV prolapse, classified as fibro-elastic deficiency (FED, n=9) and Barlow's disease (BD, n=10)...
April 2017: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/28536896/helical-distribution-of-hypertrophy-in-patients-with-hypertrophic-cardiomyopathy-prevalence-and-clinical-implications
#8
Dafne Viliani, Eduardo Pozo, Norma Aguirre, Alberto Cecconi, María J Olivera, Paloma Caballero, Luis J Jiménez-Borreguero, Fernando Alfonso
Recently a novel pattern of helical distribution of hypertrophy has been described in patients with hypertrophic cardiomyopathy (HCM). Our aim was to determine its prevalence and potential implications in an unselected cohort. One-hundred- and eight consecutive patients diagnosed with HCM by cardiac magnetic resonance (CMR) were included (median clinical follow up of 1718 days). All clinical and complementary test information was prospectively collected. The presence of a helical pattern was assessed by a simple measurement of the maximal left ventricle (LV) wall thickness (LVWT) for each of the 17 classical LV segments and it was classified in one of three types according to its extension...
May 23, 2017: International Journal of Cardiovascular Imaging
https://www.readbyqxmd.com/read/28535761/the-emerging-role-of-cardiovascular-magnetic-resonance-in-the-evaluation-of-hypertensive-heart-disease
#9
REVIEW
Sophie Mavrogeni, Vasiliki Katsi, Vasiliki Vartela, Michel Noutsias, George Markousis-Mavrogenis, Genovefa Kolovou, Athanasios Manolis
BACKGROUND: Arterial hypertension is the commonest cause of cardiovascular death. It may lead to hypertensive heart disease (HHD), including heart failure (HF), ischemic heart disease (IHD) and left ventricular hypertrophy (LVH). MAIN BODY: According to the 2007 ESH/ESC guidelines, the recommended imaging technique is echocardiography (echo), when a more sensitive detection of LVH than that provided by ECG, is needed. Cardiovascular Magnetic Resonance (CMR), a non-invasive, non-radiating technique, offers the following advantages, beyond echo: a) more reliable and reproducible measurements of cardiac parameters such as volumes, ejection fraction and cardiac mass b) more accurate differentiation of LVH etiology by providing information about tissue characterisation c) more accurate evaluation of myocardial ischemia, specifically if small vessels disease is present d) technique of choice for diagnosis of renovascular, aortic tree/branches lesions and quantification of aortic valve regurgitation e) technique of choice for treatment evaluation in clinical trials...
May 23, 2017: BMC Cardiovascular Disorders
https://www.readbyqxmd.com/read/28502640/a-cohort-study-reveals-myocarditis-to-be-a-rare-and-life-threatening-presentation-of-large-vessel-vasculitis
#10
Katie Bechman, Deepa Gopalan, Petros Nihoyannopoulos, Justin C Mason
BACKGROUND: The predominant forms of adult large vessel vasculitis (LVV) are giant cell arteritis (GCA) and Takayasu arteritis (TA). Cardiac involvement in LVV is a cause of morbidity and mortality, particularly in TA. Cardiac failure is most commonly secondary to uncontrolled arterial hypertension or myocardial ischaemia. Pulmonary hypertension and aortic valve incompetence following ascending aortic dilatation represent other serious cardiovascular complications. However, cardiac failure as a consequence of myocarditis is rarely reported, principally in single case reports or in autopsy studies...
April 4, 2017: Seminars in Arthritis and Rheumatism
https://www.readbyqxmd.com/read/28450039/characterization-of-chronic-aortic-and-mitral-regurgitation-undergoing-valve-surgery-using-cardiovascular-magnetic-resonance
#11
Christian L Polte, Sinsia A Gao, Åse A Johnsson, Kerstin M Lagerstrand, Odd Bech-Hanssen
Grading of chronic aortic regurgitation (AR) and mitral regurgitation (MR) by cardiovascular magnetic resonance (CMR) is currently based on thresholds, which are neither modality nor quantification method specific. Accordingly, this study sought to identify CMR-specific and quantification method-specific thresholds for regurgitant volumes (RVols), RVol indexes, and regurgitant fractions (RFs), which denote severe chronic AR or MR with an indication for surgery. The study comprised patients with moderate and severe chronic AR (n = 38) and MR (n = 40)...
March 29, 2017: American Journal of Cardiology
https://www.readbyqxmd.com/read/28318537/cardiac-magnetic-resonance-imaging-in-suspected-blunt-cardiac-injury-a-prospective-pilot-cohort-study
#12
Aidan Jc Burrell, David M Kaye, Mark C Fitzgerald, David J Cooper, James L Hare, Benedict T Costello, Andrew J Taylor
INTRODUCTION: The aim of this study was to evaluate the incidence and severity of blunt cardiac injury (BCI) as determined by cardiac magnetic resonance imaging (CMR), and to compare this to currently used diagnostic methods in severely injured patients. MATERIALS AND METHODS: We conducted a prospective, pilot cohort study of 42 major trauma patients from July 2013 to Jan 2015. The cohort underwent CMR within 7 days, enrolling 21 patients with evidence of chest injury and an elevated Troponin I compared to 21 patients without chest injury who acted as controls...
May 2017: Injury
https://www.readbyqxmd.com/read/28317480/novel-insights-into-complex-cardiovascular-pathologies-using-4d-flow-analysis-by-cardiovascular-magnetic-resonance-imaging
#13
Adam James Lewandowski, Betty Raman, Rajarshi Banerjee, Matteo Milanesi
BACKGROUND: It is essential that we are able to assess variations in blood flow in order to fully understand cardiovascular function in disease pathologies and for identification of individuals at long-term risk of cardiovascular disease development. Qualitative and quantitative assessments of blood flow by imaging modalities have been limited, and much of the accurate quantification has relied on invasive measures. METHODS: This review discusses how four-dimensional velocity cardiovascular magnetic resonance (4D flow CMR) offers increasing potential for the non-invasive assessment of blood flow in the heart and major blood vessels such as the aorta...
March 17, 2017: Current Pharmaceutical Design
https://www.readbyqxmd.com/read/28303211/real-time-three-dimensional-echocardiography-characterization-of-cardiac-anatomy-and-function-current-clinical-applications-and-literature-review-update
#14
REVIEW
Omar Velasco, Morgan Q Beckett, Aaron W James, Megan N Loehr, Taylor G Lewis, Tahmin Hassan, Rajesh Janardhanan
Our review of real-time three-dimensional echocardiography (RT3DE) discusses the diagnostic utility of RT3DE and provides a comparison with two-dimensional echocardiography (2DE) in clinical cardiology. A Pubmed literature search on RT3DE was performed using the following key words: transthoracic, two-dimensional, three-dimensional, real-time, and left ventricular (LV) function. Articles included perspective clinical studies and meta-analyses in the English language, and focused on the role of RT3DE in human subjects...
2017: BioResearch Open Access
https://www.readbyqxmd.com/read/28292302/impact-of-left-ventricular-outflow-tract-ellipticity-on-the-grading-of-aortic-stenosis-in-patients-with-normal-ejection-fraction
#15
Frédéric Maes, Sophie Pierard, Christophe de Meester, Jamila Boulif, Mihaela Amzulescu, David Vancraeynest, Anne-Catherine Pouleur, Agnès Pasquet, Bernhard Gerber, Jean-Louis Vanoverschelde
BACKGROUND: The pathophysiology of paradoxical low-gradient (LG) severe aortic stenosis (SAS) remains controversial. As low transvalvular flow has been implicated, we sought to investigate the impact of left ventricular outflow tract (LVOT) ellipticity on the estimation of the LV stroke volume, the calculation of the aortic valve area (AVA) by use of the continuity equation and on AS severity grading. METHODS: We studied 190 consecutive patients (mean age: 72 ± 13 years; male: 57%) with SAS (indexed AVA < 0...
March 15, 2017: Journal of Cardiovascular Magnetic Resonance
https://www.readbyqxmd.com/read/28275558/myocardial-strain-and-symptom-severity-in-severe-aortic-stenosis-insights-from-cardiovascular-magnetic-resonance
#16
Tarique Al Musa, Akhlaque Uddin, Peter P Swoboda, Pankaj Garg, Timothy A Fairbairn, Laura E Dobson, Christopher D Steadman, Anvesha Singh, Bara Erhayiem, Sven Plein, Gerald P McCann, John P Greenwood
BACKGROUND: Symptomatic severe aortic stenosis (AS) is a class I indication for replacement in patients when left ventricular ejection fraction (LVEF) is preserved. However, symptom reporting is often equivocal and decision making can be challenging. We aimed to quantify myocardial deformation using cardiovascular magnetic resonance (CMR) in patients classified by symptom severity. METHODS: Forty-two patients with severe AS referred to heart valve clinic were studied using tagged CMR imaging...
February 2017: Quantitative Imaging in Medicine and Surgery
https://www.readbyqxmd.com/read/28270219/quantification-of-aortic-stenosis-diagnostic-parameters-comparison-of-fast-3-direction-and-1-direction-phase-contrast-cmr-and-transthoracic-echocardiography
#17
Juliana Serafim da Silveira, Matthew Smyke, Adam V Rich, Yingmin Liu, Ning Jin, Debbie Scandling, Jennifer A Dickerson, Carlos E Rochitte, Subha V Raman, Lee C Potter, Rizwan Ahmad, Orlando P Simonetti
BACKGROUND: Aortic stenosis (AS) is a common valvular disorder, and disease severity is currently assessed by transthoracic echocardiography (TTE). However, TTE results can be inconsistent in some patients, thus other diagnostic modalities such as cardiovascular magnetic resonance (CMR) are demanded. While traditional unidirectional phase-contrast CMR (1Dir PC-CMR) underestimates velocity if the imaging plane is misaligned to the flow direction, multi-directional acquisitions are expected to improve velocity measurement accuracy...
March 7, 2017: Journal of Cardiovascular Magnetic Resonance
https://www.readbyqxmd.com/read/28236163/comparison-of-patients-undergoing-surgical-versus-transcatheter-pulmonary-valve-replacement-criteria-for-referral-and-mid-term-outcome
#18
COMPARATIVE STUDY
Jenny E Zablah, Nilanjana Misra, Dorota Gruber, Dipak Kholwadwala, Shilpi Epstein
Pulmonary regurgitation and/or stenosis (PS) is challenging in patients with congenital heart defects. Our aim was to identify if criteria for referral were different between surgical (SPVR) and transcatheter pulmonary valve replacement (TPVR) populations, and to further assess if any baseline differences influence the resultant ventricular remodeling at medium-term follow-up. Retrospective chart review of patients post-SPVR or TPVR at our center from 2013 to 2015 was conducted. Volumetric data from cardiac magnetic resonance (CMR), 1 year before and 1 year after PVR was obtained...
March 2017: Pediatric Cardiology
https://www.readbyqxmd.com/read/28222756/proximal-aortic-stiffening-in-turner-patients-may-be-present-before-dilation-can-be-detected-a-segmental-functional-mri-study
#19
Daniel G H Devos, Katya De Groote, Danilo Babin, Laurent Demulier, Yves Taeymans, Jos J Westenberg, Luc Van Bortel, Patrick Segers, Eric Achten, Jean De Schepper, Ernst Rietzschel
BACKGROUND: To study segmental structural and functional aortic properties in Turner syndrome (TS) patients. Aortic abnormalities contribute to increased morbidity and mortality of women with Turner syndrome. Cardiovascular magnetic resonance (CMR) allows segmental study of aortic elastic properties. METHOD: We performed Pulse Wave Velocity (PWV) and distensibility measurements using CMR of the thoracic and abdominal aorta in 55 TS-patients, aged 13-59y, and in a control population (n = 38;12-58y)...
February 13, 2017: Journal of Cardiovascular Magnetic Resonance
https://www.readbyqxmd.com/read/28222749/the-impact-of-trans-catheter-aortic-valve-replacement-induced-left-bundle-branch-block-on-cardiac-reverse-remodeling
#20
Laura E Dobson, Tarique A Musa, Akhlaque Uddin, Timothy A Fairbairn, Owen J Bebb, Peter P Swoboda, Philip Haaf, James Foley, Pankaj Garg, Graham J Fent, Christopher J Malkin, Daniel J Blackman, Sven Plein, John P Greenwood
BACKGROUND: Left bundle branch block (LBBB) is common following trans-catheter aortic valve replacement (TAVR) and has been linked to increased mortality, although whether this is related to less favourable cardiac reverse remodeling is unclear. The aim of the study was to investigate the impact of TAVR induced LBBB on cardiac reverse remodeling. METHODS: 48 patients undergoing TAVR for severe aortic stenosis were evaluated. 24 patients with new LBBB (LBBB-T) following TAVR were matched with 24 patients with a narrow post-procedure QRS (nQRS)...
February 22, 2017: Journal of Cardiovascular Magnetic Resonance
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