keyword
MENU ▼
Read by QxMD icon Read
search

urea excretion

keyword
https://www.readbyqxmd.com/read/29344901/imaging-characteristics-and-first-experience-of-68ga-thp-psma-a-novel-probe-for-rapid-kit-based-ga-68-labeling-and-pet-imaging-comparative-analysis-with-68ga-psma-i-t
#1
Thorsten Derlin, Sebastian Schmuck, Cathleen Juhl, Steffi Teichert, Johanna Zörgiebel, Hans-Jürgen Wester, Sophie M Schneefeld, Almut C A Walte, James T Thackeray, Tobias L Ross, Frank M Bengel
PURPOSE: [68Ga]Trishydroxypyridinone (THP)-prostate-specific membrane antigen (PSMA) is a novel tracer that can be labeled in one step by cold reconstitution of a kit with unprocessed generator eluate, targeting PSMA via the lysine-urea-glutamate (KuE) motif. The aim of this study was to evaluate the human imaging characteristics of [68Ga]THP-PSMA. PROCEDURES: [68Ga]THP-PSMA positron emission tomography (PET)/x-ray computed tomography (CT) was performed in 25 patients with biochemical recurrence after radical prostatectomy for prostate cancer...
January 17, 2018: Molecular Imaging and Biology: MIB: the Official Publication of the Academy of Molecular Imaging
https://www.readbyqxmd.com/read/29341028/ameliorative-effects-of-zataria-multiflora-hydro-alcoholic-extract-on-gentamicin-induced-nephrotoxicity-in-rats
#2
Saeed Hajihashemi, Tahereh Jafarian, Mahboubeh Ahmadi, Ali Rahbari, Fatemeh Ghanbari
BACKGROUND: Nephrotoxicity is the major side effects of aminoglycoside antibiotics such as gentamicin. The aim of this study was to investigate the therapeutic effects of Z.multiflora (ZM) hydroalcoholic extract on gentamicin-induced nephrotoxicity. METHODS: Twenty-eight male Wistar rats categorized into four groups: 1) the control group without injection, 2) the gentamicin treated group (100 mg/kg, i.p) 3) the gentamicin and Z. Multiflora treated group; Z. Multiflora extract(0...
January 16, 2018: Drug Research
https://www.readbyqxmd.com/read/29340320/association-of-a-low-protein-diet-with-slower-progression-of-ckd
#3
Marie Metzger, Wen Lun Yuan, Jean-Philippe Haymann, Martin Flamant, Pascal Houillier, Eric Thervet, Jean-Jacques Boffa, François Vrtovsnik, Marc Froissart, Lise Bankir, Denis Fouque, Bénédicte Stengel
Introduction: Reducing protein intake is recommended for slowing chronic kidney disease (CKD) progression, but assessment of its true effectiveness is sparse. Methods: Using the Maroni formula, we assessed dietary protein intake (DPI) from 24-hour urinary urea excretion in 1594 patients (67% men and 33% women) with CKD, 784 of whom also had 7-day food records. Cause-specific hazard ratios (HRs) and 95% confidence intervals for the competing risks of DPI-associated end-stage renal disease (ESRD) or death were estimated in 1412 patients with baseline glomerular filtration rate ≥15 ml/min per 1...
January 2018: KI Reports
https://www.readbyqxmd.com/read/29315697/fractional-excretion-of-urea-a-simple-tool-for-the-differential-diagnosis-of-acute-kidney-injury-in-cirrhosis
#4
Kavish R Patidar, Le Kang, Jasmohan S Bajaj, Daniel Carl, Arun J Sanyal
Current approaches to determine the cause of acute kidney injury (AKI) in patients with cirrhosis are suboptimal. The aim of this study was to determine the utility of fractional excretion of urea (FEUrea) for the differential diagnosis of AKI in cirrhotic patients. A retrospective analysis was performed in patients (n=50) with cirrhosis and ascites admitted with AKI. Using adjudicated etiology assessment as the reference standard, receiver operating curves (ROC) and optimal cutoff, sensitivity (Sn) and specificity (Sp) for the diagnosis of prerenal azotemia (PRA), type 1 hepatorenal syndrome (HRS) and acute tubular necrosis (ATN) was derived...
January 8, 2018: Hepatology: Official Journal of the American Association for the Study of Liver Diseases
https://www.readbyqxmd.com/read/29315212/higher-protein-intake-is-not-associated-with-decreased-kidney-function-in-pre-diabetic-older-adults-following-a-one-year-intervention-a-preview-sub-study
#5
Grith Møller, Jens Rikardt Andersen, Christian Ritz, Marta P Silvestre, Santiago Navas-Carretero, Elli Jalo, Pia Christensen, Elizabeth Simpson, Moira Taylor, J Alfredo Martinez, Ian Macdonald, Nils Swindell, Kelly A Mackintosh, Gareth Stratton, Mikael Fogelholm, Thomas M Larsen, Sally D Poppitt, Lars O Dragsted, Anne Raben
Concerns about detrimental renal effects of a high-protein intake have been raised due to an induced glomerular hyperfiltration, since this may accelerate the progression of kidney disease. The aim of this sub-study was to assess the effect of a higher intake of protein on kidney function in pre-diabetic men and women, aged 55 years and older. Analyses were based on baseline and one-year data in a sub-group of 310 participants included in the PREVIEW project (PREVention of diabetes through lifestyle Intervention and population studies in Europe and around the World)...
January 9, 2018: Nutrients
https://www.readbyqxmd.com/read/29306350/effect-of-condensed-tannins-in-rations-of-lactating-dairy-cows-on-production-variables-and-nitrogen-use-efficiency
#6
K Gerlach, M Pries, E Tholen, A J Schmithausen, W Büscher, K-H Südekum
The objective of this study was to evaluate the effect of supplemented condensed tannins (CT) from the bark of the Black Wattle tree (Acacia mearnsii) on production variables and N use efficiency in high yielding dairy cows. A feeding trial with 96 lactating German Holstein cows was conducted for a total of 169 days, divided into four periods. The animals were allotted to two groups (control (CON) and experimental (EXP) group) according to milk yield in previous lactation, days in milk (98), number of lactations and BW...
January 8, 2018: Animal: An International Journal of Animal Bioscience
https://www.readbyqxmd.com/read/29278442/sevelamer-hydrochloride-suppresses-proliferation-of-parathyroid-cells-during-the-early-phase-of-chronic-renal-failure-in-rats
#7
Xiao Xiao, Yan Liu, Xiaoshi Zhong, Daoyuan Zhou, Xuan Xiong
AIM: We examined the effects of sevelamer on parathyroid cell proliferation and secondary hyperparathyroidism in rats following induction of early-phase early phase of chronic renal failure (CRF) by unilateral ureteral obstruction (UUO). METHODS: For 5 days, rats in the control group received normal food, rats in the sevelamer group (SH) received control food plus 5% sevelamer, and rats in the low protein group (LP) received low protein food. Five rats of each group were sacrificed at baseline (d0)...
December 26, 2017: Nephrology
https://www.readbyqxmd.com/read/29274976/replacing-ground-corn-with-incremental-amounts-of-liquid-molasses-does-not-change-milk-enterolactone-but-decreases-production-in-dairy-cows-fed-flaxseed-meal
#8
C P Ghedini, D C Moura, R A V Santana, A S Oliveira, A F Brito
We investigated the effects of replacing ground corn (GRC) with incremental amounts of liquid molasses (LM) on milk enterolactone concentration, antioxidant enzymes activity in plasma, production, milk fatty acid (FA) profile, and nutrient utilization in Jersey cows fed flaxseed meal and low-starch diets. Sixteen multiparous organically certified Jersey cows averaging (mean ± standard deviation) 101 ± 45 d in milk, 462 ± 38 kg of body weight, and 19.8 ± 3.90 kg/d of milk in the beginning of the study were randomly assigned to treatment sequences in a replicated 4 × 4 Latin square design, with 14 d for diet adaptation and 7 d for data and sample collection...
December 20, 2017: Journal of Dairy Science
https://www.readbyqxmd.com/read/29239015/treating-hepatic-encephalopathy-in-cirrhotic-patients-admitted-to-icu-with-sodium-phenylbutyrate-a-preliminary-study
#9
Nicolas Weiss, Simona Tripon, Marion Lodey, Elsa Guiller, Helga Junot, Denis Monneret, Julien Mayaux, Hélène Brisson, Maxime Mallet, Marika Rudler, Françoise Imbert-Bismut, Dominique Thabut
Hepatic encephalopathy (HE) influences short and long-term prognosis. Recently, glycerol phenylbutyrate (PB), that lowers ammonia by providing an alternate pathway to urea for waste nitrogen excretion, has shown that it was effective in preventing the occurrence of HE in RCT. The aim was to assess the benefits of sodium PB in cirrhotic patients admitted in ICU for overt HE, in terms of ammonia levels decrease, neurological improvement and survival. Cirrhotic patients who presented with overt HE, ammonia levels >100 μmol/L, and did not display any contra-indication were included...
December 14, 2017: Fundamental & Clinical Pharmacology
https://www.readbyqxmd.com/read/29224883/utilization-of-protein-in-red-clover-and-alfalfa-silages-by-lactating-dairy-cows-and-growing-lambs
#10
Glen A Broderick
Feeding trials were conducted with lactating cows and growing lambs to quantify effects of replacing dietary alfalfa silage (AS) with red clover silage (RCS) on nutrient utilization. The lactation trial had a 2 × 4 arrangement of treatments: AS or RCS fed with no supplement, rumen-protected Met (RPM), rumen-protected Lys (RPL), or RPM plus RPL. Grass silage was fed at 13% of dry matter (DM) with AS to equalize dietary neutral detergent fiber (NDF) and crude protein contents. All diets contained (DM basis) 5% corn silage and 16% crude protein...
December 7, 2017: Journal of Dairy Science
https://www.readbyqxmd.com/read/29215154/analysis-of-factors-predicting-the-response-to-tolvaptan-in-patients-with-liver-cirrhosis-and-hepatic-edema
#11
Masanori Atsukawa, Akihito Tsubota, Keizo Kato, Hiroshi Abe, Noritomo Shimada, Toru Asano, Tadashi Ikegami, Mai Koeda, Tomomi Okubo, Taeang Arai, Ai Nakagawa-Iwashita, Yuji Yoshida, Korenobu Hayama, Norio Itokawa, Chisa Kondo, Yoshimichi Chuganji, Yasushi Matsuzaki, Katsuhiko Iwakiri
BACKGROUND AND AIM: This study aimed to clarify the factors predictive of treatment response to tolvaptan (V2-receptor antagonist) for cirrhotic patients with hepatic edema in a real-world setting. METHODS: In this retrospective, multicenter study, tolvaptan was orally administered at a dose of 7.5 mg once a day. Patients with a decrease in body weight of 1.5 kg or greater from baseline were characterized as responders at day 7. RESULTS: Of 229 patients, 210 were subjected to this analysis...
December 7, 2017: Journal of Gastroenterology and Hepatology
https://www.readbyqxmd.com/read/29211750/chow-fed-uc-davis-strain-female-lepr-fatty-zucker-rats-exhibit-mild-glucose-intolerance-hypertriglyceridemia-and-increased-urine-volume-all-reduced-by-a-brown-norway-strain-chromosome-1-congenic-donor-region
#12
Craig H Warden, Ahmed Bettaieb, Esther Min, Janis S Fisler, Fawaz G Haj, Judith S Stern
Our objective is to identify genes that influence the development of any phenotypes of type 2 diabetes (T2D) or kidney disease in obese animals. We use the reproductively isolated UC Davis fatty Zucker strain rat model in which the defective chromosome 4 leptin receptor (LeprfaSte/faSte) results in fatty obesity. We previously produced a congenic strain with the distal half of chromosome 1 from the Brown Norway strain (BN) on a Zucker (ZUC) background (BN.ZUC-D1Rat183-D1Rat90). Previously published studies in males showed that the BN congenic donor region protects from some phenotypes of renal dysfunction and T2D...
2017: PloS One
https://www.readbyqxmd.com/read/29207360/oridonin-protects-against-the-inflammatory-response-in-diabetic-nephropathy-by-inhibiting-the-tlr4-p38-mapk-and-tlr4-nf-%C3%AE%C2%BAb-signaling-pathways
#13
Jushuang Li, Liping Bao, Dongqing Zha, Lian Zhang, Ping Gao, Juan Zhang, Xiaoyan Wu
Inflammation plays a pivotal role in the development and progression of diabetic nephropathy (DN). Oridonin (Ori), a component isolated from Rabdosia rubescens, possesses remarkable anti-inflammatory, immunoregulatory and antitumor properties. However, the renoprotective effects of Ori and the underlying molecular mechanisms have not been explored in DN. In this study, we aimed to investigate the protective effects and potential mechanisms responsible for the anti-inflammatory effects of Ori in diabetes-induced renal injury in vivo and in vitro...
December 2, 2017: International Immunopharmacology
https://www.readbyqxmd.com/read/29204988/effects-of-dietary-fresh-fermented-soybean-meal-on-growth-performance-ammonia-and-particulate-matter-emissions-and-nitrogen-excretion-in-nursery-piglets
#14
Sai-Sai Cheng, Yuan Li, Shi-Jie Geng, Luan-Sha Hu, Xiong-Feng Fu, Xin-Yan Han
This study was conducted to investigate the effects of fresh fermented soybean meal (FSM) on the growth performance of nursery piglets, nitrogen excretion in feces, and the concentrations of ammonia (NH3) and particulate matter (PM) in the piggery. A total of 472 nursery piglets (Landrace×Yorkshire, (16.3±0.36) kg body weight) were randomly allocated into two treatments with 236 pigs in each treatment. The pigs were fed the basal diet without fresh FSM (control) or diet containing 10% (100 g/kg) fresh FSM (FSM group), and the crude protein content of the two groups was consistent...
2017: Journal of Zhejiang University. Science. B
https://www.readbyqxmd.com/read/29197231/uptake-and-effects-of-2-4-6-trinitrotoluene-tnt-in-juvenile-atlantic-salmon-salmo-salar
#15
Espen Mariussen, Siv Marie Stornes, Kari Oline Bøifot, Bjørn Olav Rosseland, Brit Salbu, Lene Sørlie Heier
Organ specific uptake and depuration, and biological effects in Atlantic salmon (Salmo salar) exposed to 2, 4, 6-trinitrotoluene (TNT) were studied. Two experiments were conducted, the first using radiolabeled TNT (14C-TNT, 0.16mg/L) to study uptake (48h) and depuration (48h), while the second experiment focused on physiological effects in fish exposed to increasing concentrations of unlabeled TNT (1μg-1mg/L) for 48h. The uptake of 14C-TNT in the gills and most of the organs increased rapidly during the first 6h of exposure (12h in the brain) followed by a rapid decrease even though the fish were still exposed to TNT in the water...
November 24, 2017: Aquatic Toxicology
https://www.readbyqxmd.com/read/29189935/the-physiology-of-the-tambaqui-colossoma-macropomum-at-ph-8-0
#16
Chris M Wood, R J Gonzalez, Márcio Soares Ferreira, Susana Braz-Mota, Adalberto Luis Val
The Tambaqui is a model neotropical teleost which is of great economic and cultural importance in artisanal fisheries and commercial aquaculture. It thrives in ion-poor, often acidic Amazonian waters and exhibits excellent regulation of physiology down to water pH 4.0. Curiously, however, it is reported to perform poorly in aquaculture at pH 8.0, an only slightly alkaline pH which would be benign for most freshwater fish. In initial experiments with Tambaqui of intermediate size (30-50 g), we found that ammonia excretion rate was unchanged at pH 4, 5, 6, and 7, but elevated after 20-24 h at pH 8, exactly opposite the pattern seen in most teleosts...
November 30, 2017: Journal of Comparative Physiology. B, Biochemical, Systemic, and Environmental Physiology
https://www.readbyqxmd.com/read/29152212/sevoflurane-and-renal-function-a-meta-analysis-of-randomized-trials
#17
Lady Christine L Ong Sio, Richard Glenn C Dela Cruz, Alexander F Bautista
Objective: This study aims to describe the overall cumulative effect of sevoflurane on kidney function in healthy patients in terms of mean plasma creatinine, blood urea nitrogen (BUN), creatinine clearance, urinary protein, and glucose excretion at 24 and 72 hours post-anesthesia. Data retrieval: A systematic literature search using MEDLINE and EMBASE as primary search engines was conducted. Articles, relevant abstracts, and citations dated January 1, 1995 to June 30, 2016 were retrieved...
July 2017: Medical Gas Research
https://www.readbyqxmd.com/read/29148979/role-of-caftaric-acid-in-lead-associated-nephrotoxicity-in-rats-via-antidiuretic-antioxidant-and-anti-apoptotic-activities
#18
Khaled M M Koriem, Mahmoud S Arbid
Background Lead is a toxic metal that is widely distributed in the environment where caftaric acid (CA) is the ester form of caffeic acid where CA is the major dietary polyphenol present in various foods and beverages. The aim of this study was to evaluate the effect of CA in lead acetate (LA)-associated nephrotoxicity through antidiuretic, antioxidant and anti-apoptotic activities. Methods Forty-eight male albino rats divided into six equal groups; group 1 control injected intraperitoneally (ip) with saline (1 mL/kg of bw) over two weeks period, group 2 injected ip with CA (80 mg/kg of bw) over two weeks period, groups 3, 4, 5 and 6 injected ip with 100 μmol/kg of bw LA over two weeks period where groups 4, 5 & 6 co-injected ip with 1-deamino-8-D-arginine vasopressin (dDAVP) drug (1 mg/kg of bw), CA (40 mg/kg of bw), and CA (80 mg/kg of bw), respectively...
November 17, 2017: Journal of Complementary & Integrative Medicine
https://www.readbyqxmd.com/read/29123839/relationship-between-nitrogen-loss-and-blood-urea-nitrogen-concentrations-in-patients-requiring-continuous-renal-replacement-therapy
#19
Takeaki Sato, Shigeki Kushimoto
Aim: It is well known that continuous renal replacement therapy (CRRT) produces some amount of nitrogen loss, but there are few tools that are easily applied to measure it. This study aimed to evaluate nitrogen loss using blood urea nitrogen (BUN) measurement in patients receiving CRRT. Methods: The subjects were 28 patients who received CRRT (except for liver failure) between 2010 and 2012. Nutrition data and nitrogen excretion in dialysate and urine were measured...
January 2017: Acute Medicine & Surgery
https://www.readbyqxmd.com/read/29108052/comparison-of-nitrogen-utilization-and-urea-kinetics-between-yaks-bos-grunniens-and-indigenous-cattle-bos-taurus
#20
J W Zhou, C L Zhong, H Liu, A A Degen, E C Titgemeyer, L M Ding, Z H Shang, X S Guo, Q Qiu, Z P Li, G Yang, R J Long
Under traditional management on the Qinghai-Tibetan Plateau, yaks () graze only on natural pasture without supplements and are forced to cope with sparse forage of low N content, especially in winter. In contrast, indigenous Tibetan yellow cattle () require supplements during the cold season. We hypothesized that, in response to harsh conditions, yaks cope with low N intakes better than cattle. To test this hypothesis, a study of whole-body N retention and urea kinetics was conducted in 2 concurrent 4 × 4 Latin squares, with 1 square using yaks and 1 square using cattle...
October 2017: Journal of Animal Science
keyword
keyword
82893
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"