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https://www.readbyqxmd.com/read/28742491/the-canary-in-the-coalmine-bee-declines-as-an-indicator-of-environmental-health
#1
Dave Goulson, Elizabeth Nicholls
Bee declines have received much attention of late, but there is considerable debate and confusion as to the extent, significance and causes of declines. In part, this reflects conflation of data for domestic honeybees, numbers of which are largely driven by economic factors, with those for wild bees, many of which have undergone marked range contractions but for the majority of which we have no good data on population size. There is no doubt that bees are subject to numerous pressures in the modern world. The abundance and diversity of flowers has declined along with availability of suitable nest sites, bees are chronically exposed to cocktails of agrochemicals, and they are simultaneously exposed to novel parasites and pathogens accidentally spread by humans...
September 1, 2016: Science Progress
https://www.readbyqxmd.com/read/28742251/evolution-of-volatile-emission-in-rhus-coriaria-organs-during-different-stages-of-growth-and-evaluation-of-the-essential-oil-composition
#2
Rose Vanessa Bandeira Reidel, Pier Luigi Cioni, Luigi Majo, Luisa Pistelli
Rhus coriaria, also known as sumac, have been traditionally used in many countries as spice, condiment, dying agent and medicinal herb. The chemical composition of essential oils and the volatile emissions from different organs of this species collected in Sicily (Italy) were analyzed by GC-FID and GC-MS. Monoterpene and sesquiterpene hydrocarbons were the most abundant class in the volatile emissions with β-caryophyllene and α-pinene were the main constituents in the majority of the examined samples. The EO composition was characterized by high amount of monoterpene and sesquiterpene hydrocarbons together with diterpenes...
July 25, 2017: Chemistry & Biodiversity
https://www.readbyqxmd.com/read/28742230/allopatric-speciation-despite-historical-gene-flow-divergence-and-hybridization-in-carex-furva-and-c-lucennoiberica-cyperaceae-inferred-from-plastid-and-nuclear-rad-seq-data
#3
E Maguilla, M Escudero, A L Hipp, M Luceño
Gene flow among incipient species can act as a creative or destructive force in the speciation process, generating variation on which natural selection can act while, potentially, undermining population divergence. The flowering plant genus Carex exhibits a rapid and relatively recent radiation with many species limits still unclear. This is the case with the Iberian Peninsula (Spain and Portugal) endemic C. lucennoiberica, which lay unrecognized within Carex furva until its recent description as a new species...
July 25, 2017: Molecular Ecology
https://www.readbyqxmd.com/read/28742220/dissecting-functions-of-sepallata-like-mads-box-genes-in-patterning-of-the-pseudanthial-inflorescence-of-gerbera-hybrida
#4
Teng Zhang, Yafei Zhao, Inka Juntheikki, Katriina Mouhu, Suvi K Broholm, Anneke S Rijpkema, Lisa Kins, Tianying Lan, Victor A Albert, Teemu H Teeri, Paula Elomaa
The pseudanthial inflorescences of the sunflower family, Asteraceae, mimic a solitary flower but are composed of multiple flowers. Our studies in Gerbera hybrida indicate functional diversification for SEPALLATA (SEP)-like MADS box genes that often function redundantly in other core eudicots. We conducted phylogenetic and expression analysis for eight SEP-like GERBERA REGULATOR OF CAPITULUM DEVELOPMENT (GRCD) genes, including previously unstudied gene family members. Transgenic gerbera plants were used to infer gene functions...
July 25, 2017: New Phytologist
https://www.readbyqxmd.com/read/28741704/methylation-of-protein-phosphatase-2a-influence-of-regulators-and-environmental-stress-factors
#5
Maria T Creighton, Anna Kolton, Amr R A Kataya, Jodi Maple-Grødem, Irina O Averkina, Behzad Heidari, Cathrine Lillo
Protein phosphatase 2A catalytic subunit (PP2A-C) has a terminal leucine subjected to methylation, a regulatory mechanism conserved from yeast to mammals and plants. Two enzymes, LCMT1 and PME1, methylate and demethylate PP2A-C, respectively. The physiological importance of these posttranslational modifications is still enigmatic. We investigated these processes in Arabidopsis thaliana by mutant phenotyping, global expression analysis, and by monitoring methylation status of PP2A-C under different environmental conditions...
July 25, 2017: Plant, Cell & Environment
https://www.readbyqxmd.com/read/28741428/corrigendum
#6
(no author information available yet)
Frankis J, Goodall L, Clutterbuck D, Abubakari A-R and Flowers P. Regular STI testing amongst men who have sex with men and use social media is suboptimal - a cross-sectional study. International Journal of STD & AIDS 2017; 28: 573-583. DOI: 10.1177/0956462416636780. Razak Abubakari would like to change the presentation of his name in the online version of this article to Abdul-Razak Abubakari.
August 2017: International Journal of STD & AIDS
https://www.readbyqxmd.com/read/28740501/hac1-and-haf1-histone-acetyltransferases-have-different-roles-in-uv-b-responses-in-arabidopsis
#7
Julieta P Fina, Fiorella Masotti, Sebastián P Rius, Franco Crevacuore, Paula Casati
Arabidopsis has 12 histone acetyltransferases grouped in four families: the GNAT/HAG, the MYST/HAM, the p300/CBP/HAC and the TAFII250/HAF families. We previously showed that ham1 and ham2 mutants accumulated higher damaged DNA after UV-B exposure than WT plants. In contrast, hag3 RNA interference transgenic plants showed less DNA damage and lower inhibition of plant growth by UV-B, and increased levels of UV-B-absorbing compounds. These results demonstrated that HAM1, HAM2, and HAG3 participate in UV-B-induced DNA damage repair and signaling...
2017: Frontiers in Plant Science
https://www.readbyqxmd.com/read/28740500/dna-methylation-influences-chlorogenic-acid-biosynthesis-in-lonicera-japonica-by-mediating-ljbzip8-to-regulate-phenylalanine-ammonia-lyase-2-expression
#8
Liangping Zha, Shuang Liu, Juan Liu, Chao Jiang, Shulin Yu, Yuan Yuan, Jian Yang, Yaolong Wang, Luqi Huang
The content of active compounds differ in buds and flowers of Lonicera japonica (FLJ) and L. japonica var. chinensis (rFLJ). Chlorogenic acid (CGAs) were major active compounds of L. japonica and regarded as measurements for quality evaluation. However, little is known concerning the formation of active compounds at the molecular level. We quantified the major CGAs in FLJ and rFLJ, and found the concentrations of CGAs were higher in the buds of rFLJ than those of FLJ. Further analysis of CpG methylation of CGAs biosynthesis genes showed differences between FLJ and rFLJ in the 5'-UTR of phenylalanine ammonia-lyase 2 (PAL2)...
2017: Frontiers in Plant Science
https://www.readbyqxmd.com/read/28739629/charting-the-future-of-cancer-health-disparities-research-a-position-statement-from-the-american-association-for-cancer-research-the-american-cancer-society-the-american-society-of-clinical-oncology-and-the-national-cancer-institute
#9
Blase N Polite, Lucile L Adams-Campbell, Otis W Brawley, Nina Bickell, John M Carethers, Christopher R Flowers, Margaret Foti, Scarlett Lin Gomez, Jennifer J Griggs, Christopher S Lathan, Christopher I Li, J Leonard Lichtenfeld, Worta McCaskill-Stevens, Electra D Paskett
No abstract text is available yet for this article.
July 24, 2017: Cancer Research
https://www.readbyqxmd.com/read/28738442/charting-the-future-of-cancer-health-disparities-research-a-position-statement-from-the-american-association-for-cancer-research-the-american-cancer-society-the-american-society-of-clinical-oncology-and-the-national-cancer-institute
#10
Blase N Polite, Lucile L Adams-Campbell, Otis W Brawley, Nina Bickell, John M Carethers, Christopher R Flowers, Margaret Foti, Scarlett Lin Gomez, Jennifer J Griggs, Christopher S Lathan, Christopher I Li, J Leonard Lichtenfeld, Worta McCaskill-Stevens, Electra D Paskett
No abstract text is available yet for this article.
July 24, 2017: CA: a Cancer Journal for Clinicians
https://www.readbyqxmd.com/read/28738207/translocation-of-heavy-metals-from-soils-into-floral-organs-and-rewards-of-cucurbita-pepo-implications-for-plant-reproductive-fitness
#11
Erna Xun, Yanwen Zhang, Jimin Zhao, Jixun Guo
Metals and metalloids in soil could be transferred into reproductive organs and floral rewards of hyperaccumulator plants and influence their reproductive success, yet little is known whether non-hyperaccumulator plants can translocate heavy metals from soil into their floral organs and rewards (i.e., nectar and pollen) and, if so, whether plant reproduction will be affected. In our studies, summer squash (Cucurbita pepo L. cv. Golden Apple) was exposed to heavy-metal treatments during bud stage to investigate the translocation of soil-supplemented zinc, copper, nickel and lead into its floral organs (pistil, anther and nectary) and rewards (nectar and pollen) as well as floral metal accumulation effects on its reproduction...
July 21, 2017: Ecotoxicology and Environmental Safety
https://www.readbyqxmd.com/read/28737975/charting-the-future-of-cancer-health-disparities-research-a-position-statement-from-the-american-association-for-cancer-research-the-american-cancer-society-the-american-society-of-clinical-oncology-and-the-national-cancer-institute
#12
Blase N Polite, Lucile L Adams-Campbell, Otis W Brawley, Nina Bickell, John M Carethers, Christopher R Flowers, Margaret Foti, Scarlett Lin Gomez, Jennifer J Griggs, Christopher S Lathan, Christopher I Li, J Leonard Lichtenfeld, Worta McCaskill-Stevens, Electra D Paskett
No abstract text is available yet for this article.
July 24, 2017: Journal of Clinical Oncology: Official Journal of the American Society of Clinical Oncology
https://www.readbyqxmd.com/read/28737913/uplc-q-exactive-orbitrap-ms-based-lipidomics-approach-to-characterize-lipid-extracts-from-bee-pollen-and-their-in-vitro-anti-inflammatory-properties
#13
Qiangqiang Li, Xinwen Liang, Liang Zhao, Zhongyin Zhang, Xiaofeng Xue, Kai Wang, Liming Wu
Bee pollen (BP) is collected by honeybees from flower pollen mixed with nectar and its secretions, with extensive nutritional and therapeutic properties. Lipids are known to be critical contributors for the therapeutic effects of BP and vary depending on different plant sources; however, lipid profiles of BP are not available. Here, an UPLC-Q-Exactive Orbitrap/MS method was established for comprehensive lipidomics analysis of BP derived from three major nectar plants (Brassica campestris L., Camellia sinensis L...
July 24, 2017: Journal of Agricultural and Food Chemistry
https://www.readbyqxmd.com/read/28737900/accumulation-of-charantin-and-expression-of-triterpenoid-biosynthesis-genes-in-bitter-melon-momordica-charantia
#14
Do Manh Cuong, Jin Jeon, Abubaker M A Morgan, Changsoo Kim, Jae Kwang Kim, Sook Young Lee, Sang Un Park
Charantin, a natural cucurbitane type triterpenoid, has been reported to have beneficial pharmacological functions such as anticancer, antidiabetic, and antibacterial activities. However, accumulation of charantin in bitter melon has been little studied. Here, we performed a transcriptome analysis to identify genes involved in the triterpenoid biosynthesis pathway in bitter melon seedlings. Total of 88,703 transcripts with an average length of 898 bp were identified in bitter melon seedlings. Based on a functional annotation, we identified 15 candidate genes encoding enzymes related to triterpenoid biosynthesis and analyzed their expression in different organs of mature plants...
July 24, 2017: Journal of Agricultural and Food Chemistry
https://www.readbyqxmd.com/read/28737472/histone-deacetylase-hd2d-is-involved-in-regulating-plant-development-and-flowering-time-in-arabidopsis
#15
Gang Tian, Joshua Farhi, Hui Fang, Denis Maxwell, Tim Xing, Lining Tian
HD2D is one of the four plant specific HD2 family histone deacetylases (HDAC) identified in Arabidopsis and it is distantly related to the other HD2 members. At this time, little is known about the function of HD2D in plants. Here we provide evidence that HD2D is involved in the control of flowering time. Flowering was delayed in transgenic plants overexpressing HD2D and hd2d mutant plants flowered earlier compared to wild-type in both long day and short day conditions. Expression of several floral identity genes was altered in these plants...
July 24, 2017: Plant Signaling & Behavior
https://www.readbyqxmd.com/read/28737396/azacyclo-indoles-and-phenolics-from-the-flowers-of-juglans-regia
#16
Qian Li, An-Jun Deng, Li Li, Lian-Qiu Wu, Ming Ji, Hai-Jing Zhang, Zhi-Hong Li, Lin Ma, Zhi-Hui Zhang, Xiao-Guang Chen, Hai-Lin Qin
Seven new azacyclo-indoles and phenolics and four known alkaloids were isolated from the flowers of Juglans regia. Spectroscopic and chromatographic data revealed that the structures of the new compounds are 5,6,11,12-tetrahydropyrrolo[1',2':1,2]azepino[4,5-b]indole-3-carbaldehyde (1), (±)-5,6,7,11c-tetrahydro-1H-indolizino[7,8-b]indol-3(2H)-one (2), (±)-9-hydroxy-5-oxo-2,3,4,5-tetrahydro-1H-benzo[b]azepine-2-carboxamide (3), 5-(ethoxymethyl)-1-(4-hydroxyphenethyl)-1H-pyrrole-2-carbaldehyde (4), (±)-5,8-dihydroxy-4-(1H-indol-3-yl)-3,4-dihydronaphthalen-1(2H)-one (5), (±)-4-(6-amino-9H-purin-9-yl)-5,8-dihydroxy-3,4-dihydronaphthalen-1(2H)-one (6), and (±)-4-(6-amino-9H-purin-9-yl)-5-hydroxy-3,4-dihydronaphthalen-1(2H)-one (7)...
July 24, 2017: Journal of Natural Products
https://www.readbyqxmd.com/read/28736638/cost-effectiveness-of-precision-medicine-in-gastrointestinal-stromal-tumor-and-gastric-adenocarcinoma
#17
REVIEW
Simon B Zeichner, Daniel A Goldstein, Christine Kohn, Christopher R Flowers
Over the past 20 years, with the incorporation of genetic sequencing and improved understanding regarding the mechanisms of cancer growth/metastasis, novel targets and their associated treatments have emerged in oncology and are now regularly incorporated into the clinical care of patients in the US. Novel, more tumor-specific, non-chemotherapy agents, including agents that are commonly used in the treatment of patients with gastric adenocarcinoma (GA) and gastrointestinal stromal tumor (GIST), fall under a broader treatment strategy, termed "precision medicine"...
June 2017: Journal of Gastrointestinal Oncology
https://www.readbyqxmd.com/read/28736494/josephson-arbitrary-waveform-synthesis-with-multilevel-pulse-biasing
#18
Justus A Brevik, Nathan E Flowers-Jacobs, Anna E Fox, Evan B Golden, Paul D Dresselhaus, Samuel P Benz
We describe the implementation of new commercial pulse-bias electronics that have enabled an improvement in the generation of quantum-accurate waveforms both with and without low-frequency compensation biases. We have used these electronics to apply a multilevel pulse bias to the Josephson arbitrary waveform synthesizer and have generated, for the first time, a quantum-accurate bipolar sinusoidal waveform without the use of a low-frequency compensation bias current. This uncompensated 1 kHz waveform was synthesized with an rms amplitude of 325 mV and maintained its quantum accuracy over a1...
April 2017: IEEE Transactions on Applied Superconductivity: a Publication of the IEEE Superconductivity Committee
https://www.readbyqxmd.com/read/28735729/protective-effects-of-flavonoids-isolated-from-korean-milk-thistle-cirsium-japonicum-var-maackii-maxim-matsum-on-tert-butyl-hydroperoxide-induced-hepatotoxicity-in-hepg2-cells
#19
Hyun Ah Jung, Qudeer Ahmed Abdul, Jeong Su Byun, Eun-Ji Joung, Wi-Gyeong Gwon, Min-Sup Lee, Hyeung Rak Kim, Jae Sue Choi
ETHNOPHARMACOLOGICAL RELEVANCE: Milk thistle leaves and flowers have been traditionally used as herbal remedy to alleviate liver diseases for decades. Korean milk thistle, Cirsium japonicum var. maackii (Maxim.) Matsum has been employed in traditional folk medicine as diuretic, antiphlogistic, hemostatic, and detoxifying agents. AIM OF THE STUDY: The aim of current investigation was to evaluate hepatoprotective properties of the MeOH extract of the roots, stems, leaves and flowers of Korean milk thistle as well as four isolated flavonoids, luteolin, luteolin 5-O-glucoside, apigenin and apigenin 7-O-glucuronide during t-BHP-induced oxidative stress in HepG2 cells...
July 20, 2017: Journal of Ethnopharmacology
https://www.readbyqxmd.com/read/28735537/a-versatile-tetrablock-copolymer-scaffold-for-hierarchical-colloidal-nanoparticle-assemblies-synthesis-characterization-and-molecular-dynamics-simulations
#20
Gema Marcelo, Fraser P Burns, Tânia Ribeiro, José M Gaspar Martinho, M Pilar Tarazona, Enrique Saiz, Matthew G Moffitt, Jose Paulo Sequeira Farinha
A unique combination of molecular dynamics simulations and detailed multi-angle light scattering size exclusion chromatography (SEC-MALS) analysis is used to provide important a priori insights into the solution self-assembly of a well-defined and symmetric tetrablock copolymer with two acrylic acid outer blocks, two polystyrene inner blocks and a trithiocarbonate (TTC) central group, prepared by reversible addition-fragmentation chain transfer (RAFT) polymerization. SEC-MALS experiments show that the copolymer forms aggregates in both tetrahydrofuran (THF) and N-dimethylformamide (DMF), even in the presence of different salts, but not in 1,4-dioxane (dioxane)...
July 22, 2017: Langmuir: the ACS Journal of Surfaces and Colloids
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